Search Results

There are 9801 results for: content related to: A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors

  1. Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma

    Journal of Surgical Oncology

    Volume 105, Issue 3, 1 March 2012, Pages: 235–243, Yin-He Wang, Xiao-Dong Han, Yong Qiu, Jin Xiong, Yang Yu, Bin Wang, Ze-Zhang Zhu, Bang-Ping Qian, Yi-Xin Chen, Shou-Feng Wang, Hong-Fei Shi and Xu Sun

    Article first published online : 22 AUG 2011, DOI: 10.1002/jso.22077

  2. Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression

    BJU International

    Volume 107, Issue 9, May 2011, Pages: 1488–1499, Benjamin W. Turney, Gareth D.H. Turner, Simon F. Brewster and Valentine M. Macaulay

    Article first published online : 14 SEP 2010, DOI: 10.1111/j.1464-410X.2010.09556.x

  3. You have full text access to this OnlineOpen article
    Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

    Cancer

    Volume 118, Issue 9, 1 May 2012, Pages: 2454–2465, Jin-Soo Kim, Edward S. Kim, Diane Liu, J. Jack Lee, Luisa Solis, Carmen Behrens, Scott M. Lippman, Waun Ki Hong, Ignacio I. Wistuba and Ho-Young Lee

    Article first published online : 22 SEP 2011, DOI: 10.1002/cncr.26492

  4. Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma

    British Journal of Surgery

    Volume 99, Issue 3, March 2012, Pages: 387–396, C. L. Donohoe, S. L. Doyle, S. McGarrigle, M. C. Cathcart, E. Daly, A. O'Grady, J. Lysaght, G. P. Pidgeon and J. V. Reynolds

    Article first published online : 12 JAN 2012, DOI: 10.1002/bjs.8658

  5. You have full text access to this OnlineOpen article
    Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma

    Cancer

    Volume 118, Issue 14, 15 July 2012, Pages: 3484–3493, Matias E. Valsecchi, Mary McDonald, Jonathan R. Brody, Terry Hyslop, Boris Freydin, Charles J. Yeo, Charalambos Solomides, Stephen C. Peiper and Agnieszka K. Witkiewicz

    Article first published online : 15 NOV 2011, DOI: 10.1002/cncr.26661

  6. R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts

    Pediatric Blood & Cancer

    Volume 55, Issue 1, 15 July 2010, Pages: 67–75, E. Anders Kolb, Davida Kamara, Wendong Zhang, Juan Lin, Pooja Hingorani, Laurence Baker, Peter Houghton and Richard Gorlick

    Article first published online : 27 MAR 2010, DOI: 10.1002/pbc.22479

  7. Differential localization of MT1-MMP in human prostate cancer tissue: Role of IGF-1R in MT1-MMP expression

    The Prostate

    Volume 68, Issue 5, 1 April 2008, Pages: 463–476, Isis C. Sroka, Kathy McDaniel, Raymond B. Nagle and G. Tim Bowden

    Article first published online : 14 JAN 2008, DOI: 10.1002/pros.20718

  8. The adverse events profile of anti-IGF-1R monoclonal antibodies in cancer therapy

    British Journal of Clinical Pharmacology

    Volume 77, Issue 6, June 2014, Pages: 917–928, Honghai Ma, Tiehong Zhang, Hongchang Shen, Hongxin Cao and Jiajun Du

    Article first published online : 22 MAY 2014, DOI: 10.1111/bcp.12228

  9. Unique expression pattern of the three insulin receptor family members in the rat mammary gland: dominance of IGF-1R and IRR over the IR, and cyclical IGF-1R expression

    Journal of Applied Toxicology

    Volume 31, Issue 4, May 2011, Pages: 312–328, Henning Hvid, Robert Klopfleisch, Sara Vienberg, Bo F. Hansen, Inger Thorup, Henrik E. Jensen and Martin B. Oleksiewicz

    Article first published online : 24 JAN 2011, DOI: 10.1002/jat.1627

  10. You have full text access to this OnlineOpen article
    Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus

    International Journal of Cancer

    Volume 127, Issue 8, 15 October 2010, Pages: 1931–1940, Tatyana Kalinina, Maximilian Bockhorn, Jussuf T. Kaifi, Sabrina Thieltges, Cenap Güngör, Katharina E. Effenberger, Andrea Strelow, Uta Reichelt, Guido Sauter, Klaus Pantel, Jakob R. Izbicki and Emre F. Yekebas

    Article first published online : 26 JAN 2010, DOI: 10.1002/ijc.25196

  11. Sex Steroids Upregulate the IGF-1R in Prostate Cancer Cells through a Nongenotropic Pathway

    Annals of the New York Academy of Sciences

    Volume 1155, Issue 1, February 2009, Pages: 263–267, Giuseppe Pandini, Marco Genua, Francesco Frasca, Riccardo Vigneri and Antonino Belfiore

    Article first published online : 26 FEB 2009, DOI: 10.1111/j.1749-6632.2009.04361.x

  12. Effects of epidermal growth factor receptor and insulin-like growth factor 1 receptor inhibition on proliferation and intracellular signaling in cutaneous SCCHN: Potential for dual inhibition as a therapeutic modality

    Head & Neck

    Volume 35, Issue 1, January 2013, Pages: 86–93, Daniel R. Clayburgh, Neil D. Gross, Charlotte Proby, Jade Koide and Melissa H. Wong

    Article first published online : 12 APR 2012, DOI: 10.1002/hed.22936

  13. You have full text access to this OnlineOpen article
    Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma

    Cancer

    Volume 117, Issue 21, 1 November 2011, Pages: 4966–4976, Scott C. Borinstein, Donald A. Barkauskas, Mark Krailo, Daniel Scher, Lauren Scher, Silke Schlottmann, Bhaskar Kallakury, Paul S. Dickman, Bruce R. Pawel, Daniel C. West, Richard B. Womer and Jeffrey A. Toretsky

    Article first published online : 8 APR 2011, DOI: 10.1002/cncr.26112

  14. You have full text access to this OnlineOpen article
    Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes

    Immunology

    Volume 107, Issue 4, December 2002, Pages: 461–471, Patrick T. Walsh, Loraine M. Smith and Rosemary O'Connor

    Article first published online : 9 DEC 2002, DOI: 10.1046/j.1365-2567.2002.01525.x

  15. Relationship between insulin-like growth factor-1 receptor and human papillomavirus in patients with oropharyngeal cancer

    Head & Neck

    Fumihiko Matsumoto, Mitsuhisa Fujimaki, Shinichi Ohba, Masataka Kojima, Junkichi Yokoyama and Katsuhisa Ikeda

    Article first published online : 27 JUN 2014, DOI: 10.1002/hed.23702

  16. You have full text access to this OnlineOpen article
    Insulin-like growth factor-1 receptor and phosphorylated AKT-serine 473 expression in 132 resected thymomas and thymic carcinomas

    Cancer

    Volume 116, Issue 20, 15 October 2010, Pages: 4686–4695, Paolo A. Zucali, Iacopo Petrini, Elena Lorenzi, Maria Merino, Liang Cao, Luca Di Tommaso, Hye Seung Lee, Matteo Incarbone, Beatriz A. Walter, Matteo Simonelli, Massimo Roncalli, Armando Santoro and Giuseppe Giaccone

    Article first published online : 1 JUL 2010, DOI: 10.1002/cncr.25367

  17. You have full text access to this OnlineOpen article
    Altered expression of type I insulin-like growth factor receptor in Crohn's disease

    Clinical & Experimental Immunology

    Volume 139, Issue 3, March 2005, Pages: 526–533, F. El Yafi, R. Winkler, P. Delvenne, N. Boussif, J. Belaiche and E. Louis

    Article first published online : 7 FEB 2005, DOI: 10.1111/j.1365-2249.2004.02724.x

  18. Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth

    Pigment Cell & Melanoma Research

    Volume 27, Issue 2, March 2014, Pages: 297–308, Makoto Yoshida, Senthamil Selvan, Peter A. McCue, Tiziana DeAngelis, Renato Baserga, Ami Fujii, Hallgeir Rui, Michael J. Mastrangelo and Takami Sato

    Article first published online : 6 JAN 2014, DOI: 10.1111/pcmr.12206

  19. You have full text access to this OnlineOpen article
    Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors

    Cancer

    Volume 118, Issue 16, 15 August 2012, Pages: 3993–4003, Woo-Young Kim, Ludmila Prudkin, Lei Feng, Edward S. Kim, Bryan Hennessy, Ju-Seog Lee, J. Jack Lee, Bonnie Glisson, Scott M. Lippman, Ignacio I. Wistuba, Waun Ki Hong and Ho-Young Lee

    Article first published online : 22 FEB 2012, DOI: 10.1002/cncr.26656

    Corrected by:

    Erratum: Erratum

    Vol. 118, Issue 24, 6301, Article first published online: 17 MAY 2012

  20. SIRT1 silencing confers neuroprotection through IGF-1 pathway activation

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1754–1761, Luigi Sansone, Valentina Reali, Laura Pellegrini, Lidia Villanova, Michele Aventaggiato, Gabriella Marfe, Roberta Rosa, Marcella Nebbioso, Marco Tafani, Massimo Fini, Matteo A. Russo and Bruna Pucci

    Article first published online : 18 APR 2013, DOI: 10.1002/jcp.24334