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There are 15101 results for: content related to: A phase 1 study of weekly dosing of trastuzumab emtansine (T-DM1) in patients with advanced human epidermal growth factor 2–positive breast cancer

  1. Clinical Implications of Pathophysiological and Demographic Covariates on the Population Pharmacokinetics of Trastuzumab Emtansine, a HER2-Targeted Antibody-Drug Conjugate, in Patients With HER2-Positive Metastatic Breast Cancer

    The Journal of Clinical Pharmacology

    Volume 52, Issue 5, May 2012, Pages: 691–703, Dr Manish Gupta, Dr Patricia M. LoRusso, Ms Bei Wang, Ms Joo-Hee Yi, Dr Howard A. Burris III, Dr Muralidhar Beeram, Dr Shanu Modi, Dr Yu-Waye Chu, Dr Samuel Agresta, Dr Barbara Klencke, Dr Amita Joshi and Dr Sandhya Girish

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011403742

  2. Observation and modelling of main-sequence star chromospheres – XV. New constraints on the dynamo mechanisms for dM1 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 411, Issue 4, March 2011, Pages: 2259–2276, E. R. Houdebine

    Version of Record online : 14 JAN 2011, DOI: 10.1111/j.1365-2966.2010.17846.x

  3. You have free access to this content
    Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics

    Developmental Dynamics

    Volume 244, Issue 3, March 2015, Pages: 377–390, Anthony Chau and Auinash Kalsotra

    Version of Record online : 13 JAN 2015, DOI: 10.1002/dvdy.24240

  4. Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 4, October 2012, Pages: 520–527, V L Chudasama, F Schaedeli Stark, J M Harrold, J Tibbitts, S R Girish, M Gupta, N Frey and D E Mager

    Version of Record online : 12 SEP 2012, DOI: 10.1038/clpt.2012.153

  5. Prevalence of allergic symptoms among children with diabetes mellitus type 1 of different socioeconomic status

    Pediatric Diabetes

    Volume 9, Issue 4pt2, August 2008, Pages: 407–416, Kyriaki Karavanaki, Eleni Tsoka, Christina Karayianni, Vassilis Petrou, Eleni Pippidou, Maria Brisimitzi, Maria Mavrikiou, Kostas Kakleas, Ilias Konstantopoulos, Manolis Manoussakis and Catherine Dacou-Voutetakis

    Version of Record online : 29 JUL 2008, DOI: 10.1111/j.1399-5448.2008.00444.x

  6. Observation and modelling of main-sequence star chromospheres – XVIII. Observations of the Ca ii resonance lines and Hα line for dM4 stars and dK5 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 421, Issue 4, April 2012, Pages: 3189–3205, E. R. Houdebine

    Version of Record online : 13 MAR 2012, DOI: 10.1111/j.1365-2966.2012.20649.x

  7. Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes

    Neuropathology and Applied Neurobiology

    Volume 40, Issue 4, June 2014, Pages: 464–476, Massimo Santoro, Roberto Piacentini, Marcella Masciullo, Maria Laura Ester Bianchi, Anna Modoni, Maria Vittoria Podda, Enzo Ricci, Gabriella Silvestri and Claudio Grassi

    Version of Record online : 22 APR 2014, DOI: 10.1111/nan.12076

  8. Investigating the Nonclinical ADME and PK/PD of an Antibody–Drug Conjugate: A Case Study of Ado-Trastuzumab Emtansine (T-DM1)

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Jay Tibbitts

    Published Online : 30 DEC 2015, DOI: 10.1002/9780470571224.pse561

  9. Observation and modelling of main-sequence star chromospheres – XIV. Rotation of dM1 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 407, Issue 3, September 2010, Pages: 1657–1673, E. R. Houdebine

    Version of Record online : 25 AUG 2010, DOI: 10.1111/j.1365-2966.2010.16827.x

  10. You have free access to this content
    Fetal growth profiles of macrosomic and non-macrosomic infants of women with pregestational or gestational diabetes

    Ultrasound in Obstetrics & Gynecology

    Volume 41, Issue 4, April 2013, Pages: 390–397, N. M. Hammoud, G. H. A. Visser, S. A. E. Peters, E. M. Graatsma, L. Pistorius and H. W. de Valk

    Version of Record online : 10 MAR 2013, DOI: 10.1002/uog.11221

  11. Effects of Trastuzumab Emtansine (T-DM1) on QT Interval and Safety of Pertuzumab Plus T-DM1 in Patients With Previously Treated Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer

    Clinical Pharmacology in Drug Development

    Volume 2, Issue 1, January 2013, Pages: 11–24, Manish Gupta, Bei Wang, Timothy J. Carrothers, Patricia M. LoRusso, Yu-Waye Chu, Ted Shih, David Loecke, Amita Joshi, Ola Saad, Joo-Hee Yi and Sandhya Girish

    Version of Record online : 26 FEB 2013, DOI: 10.1002/cpdd.9

  12. Psychological characteristics of patients with myotonic dystrophy type 1

    Acta Neurologica Scandinavica

    Volume 132, Issue 1, July 2015, Pages: 49–58, J. A. Bertrand, S. Jean, L. Laberge, C. Gagnon, J. Mathieu, J. F. Gagnon and L. Richer

    Version of Record online : 11 DEC 2014, DOI: 10.1111/ane.12356

  13. Regional body composition and functional impairment in patients with myotonic dystrophy

    Muscle & Nerve

    Volume 44, Issue 4, October 2011, Pages: 503–508, Lelia Pruna, Jerome Chatelin, Veronique Pascal-Vigneron and Pierre Kaminsky

    Version of Record online : 8 AUG 2011, DOI: 10.1002/mus.22099

  14. Polyneuropathy in type 1 and type 2 diabetes: comparison of nerve conduction studies, thermal perception thresholds and intraepidermal nerve fibre densities

    Diabetes/Metabolism Research and Reviews

    Volume 26, Issue 2, February 2010, Pages: 100–106, Sissel Løseth, Svein I. Mellgren, Rolf Jorde, Sigurd Lindal and Erik Stålberg

    Version of Record online : 26 NOV 2009, DOI: 10.1002/dmrr.1049

  15. Sequential IL-23 and IL-17 and increased Mmp8 and Mmp14 expression characterize the progression of an experimental model of periodontal disease in type 1 diabetes

    Journal of Cellular Physiology

    Volume 227, Issue 6, June 2012, Pages: 2441–2450, Juliete A.F. Silva, Danilo L. Ferrucci, Luis A. Peroni, Patrícia G.S. Abrahão, Aline F. Salamene, Carlos Rossa-Junior, Hernandes F. Carvalho and Dagmar R. Stach-Machado

    Version of Record online : 24 FEB 2012, DOI: 10.1002/jcp.22979

  16. Dysphagia in duchenne muscular dystrophy versus myotonic dystrophy type 1

    Muscle & Nerve

    Volume 46, Issue 4, October 2012, Pages: 490–495, George Umemoto, Hirokazu Furuya, Akio Kitashima, Mitsuaki Sakai, Hajime Arahata and Toshihiro Kikuta

    Version of Record online : 13 SEP 2012, DOI: 10.1002/mus.23364

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    Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles

    Genes to Cells

    Volume 12, Issue 9, September 2007, Pages: 1035–1048, Ian Holt, Saloni Mittal, Denis Furling, Gillian S Butler-Browne, J. David Brook and Glenn E. Morris

    Version of Record online : 3 SEP 2007, DOI: 10.1111/j.1365-2443.2007.01112.x

  18. Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

    Annals of Neurology

    Volume 54, Issue 6, December 2003, Pages: 760–768, Ami Mankodi, Patana Teng-Umnuay, Matt Krym, Don Henderson, Maurice Swanson and Charles A. Thornton

    Version of Record online : 26 NOV 2003, DOI: 10.1002/ana.10763

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    Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2


    Volume 23, Issue 3, March 2015, Pages: 552–557, Spyridoula Maraka, Yogish C. Kudva, Todd A. Kellogg, Maria L. Collazo-Clavell and Manpreet S. Mundi

    Version of Record online : 22 JAN 2015, DOI: 10.1002/oby.20992

  20. Parent-reported multi-national study of the impact of congenital and childhood onset myotonic dystrophy

    Developmental Medicine & Child Neurology

    Nicholas E Johnson, Anne-Berit Ekstrom, Craig Campbell, Man Hung, Heather R Adams, Wei Chen, Elizabeth Luebbe, James Hilbert, Richard T Moxley III and Chad R Heatwole

    Version of Record online : 28 OCT 2015, DOI: 10.1111/dmcn.12948