Search Results

There are 15101 results for: content related to: A phase 1 study of weekly dosing of trastuzumab emtansine (T-DM1) in patients with advanced human epidermal growth factor 2–positive breast cancer

  1. Clinical Implications of Pathophysiological and Demographic Covariates on the Population Pharmacokinetics of Trastuzumab Emtansine, a HER2-Targeted Antibody-Drug Conjugate, in Patients With HER2-Positive Metastatic Breast Cancer

    The Journal of Clinical Pharmacology

    Volume 52, Issue 5, May 2012, Pages: 691–703, Dr Manish Gupta, Dr Patricia M. LoRusso, Ms Bei Wang, Ms Joo-Hee Yi, Dr Howard A. Burris III, Dr Muralidhar Beeram, Dr Shanu Modi, Dr Yu-Waye Chu, Dr Samuel Agresta, Dr Barbara Klencke, Dr Amita Joshi and Dr Sandhya Girish

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011403742

  2. Observation and modelling of main-sequence star chromospheres – XV. New constraints on the dynamo mechanisms for dM1 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 411, Issue 4, March 2011, Pages: 2259–2276, E. R. Houdebine

    Version of Record online : 14 JAN 2011, DOI: 10.1111/j.1365-2966.2010.17846.x

  3. You have free access to this content
    Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics

    Developmental Dynamics

    Volume 244, Issue 3, March 2015, Pages: 377–390, Anthony Chau and Auinash Kalsotra

    Version of Record online : 13 JAN 2015, DOI: 10.1002/dvdy.24240

  4. Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 4, October 2012, Pages: 520–527, V L Chudasama, F Schaedeli Stark, J M Harrold, J Tibbitts, S R Girish, M Gupta, N Frey and D E Mager

    Version of Record online : 12 SEP 2012, DOI: 10.1038/clpt.2012.153

  5. Prevalence of allergic symptoms among children with diabetes mellitus type 1 of different socioeconomic status

    Pediatric Diabetes

    Volume 9, Issue 4pt2, August 2008, Pages: 407–416, Kyriaki Karavanaki, Eleni Tsoka, Christina Karayianni, Vassilis Petrou, Eleni Pippidou, Maria Brisimitzi, Maria Mavrikiou, Kostas Kakleas, Ilias Konstantopoulos, Manolis Manoussakis and Catherine Dacou-Voutetakis

    Version of Record online : 29 JUL 2008, DOI: 10.1111/j.1399-5448.2008.00444.x

  6. Observation and modelling of main-sequence star chromospheres – XVIII. Observations of the Ca ii resonance lines and Hα line for dM4 stars and dK5 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 421, Issue 4, April 2012, Pages: 3189–3205, E. R. Houdebine

    Version of Record online : 13 MAR 2012, DOI: 10.1111/j.1365-2966.2012.20649.x

  7. Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes

    Neuropathology and Applied Neurobiology

    Volume 40, Issue 4, June 2014, Pages: 464–476, Massimo Santoro, Roberto Piacentini, Marcella Masciullo, Maria Laura Ester Bianchi, Anna Modoni, Maria Vittoria Podda, Enzo Ricci, Gabriella Silvestri and Claudio Grassi

    Version of Record online : 22 APR 2014, DOI: 10.1111/nan.12076

  8. Investigating the Nonclinical ADME and PK/PD of an Antibody–Drug Conjugate: A Case Study of Ado-Trastuzumab Emtansine (T-DM1)

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Jay Tibbitts

    Published Online : 30 DEC 2015, DOI: 10.1002/9780470571224.pse561

  9. Observation and modelling of main-sequence star chromospheres – XIV. Rotation of dM1 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 407, Issue 3, September 2010, Pages: 1657–1673, E. R. Houdebine

    Version of Record online : 25 AUG 2010, DOI: 10.1111/j.1365-2966.2010.16827.x

  10. You have free access to this content
    Fetal growth profiles of macrosomic and non-macrosomic infants of women with pregestational or gestational diabetes

    Ultrasound in Obstetrics & Gynecology

    Volume 41, Issue 4, April 2013, Pages: 390–397, N. M. Hammoud, G. H. A. Visser, S. A. E. Peters, E. M. Graatsma, L. Pistorius and H. W. de Valk

    Version of Record online : 10 MAR 2013, DOI: 10.1002/uog.11221

  11. Effects of Trastuzumab Emtansine (T-DM1) on QT Interval and Safety of Pertuzumab Plus T-DM1 in Patients With Previously Treated Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer

    Clinical Pharmacology in Drug Development

    Volume 2, Issue 1, January 2013, Pages: 11–24, Manish Gupta, Bei Wang, Timothy J. Carrothers, Patricia M. LoRusso, Yu-Waye Chu, Ted Shih, David Loecke, Amita Joshi, Ola Saad, Joo-Hee Yi and Sandhya Girish

    Version of Record online : 26 FEB 2013, DOI: 10.1002/cpdd.9

  12. Psychological characteristics of patients with myotonic dystrophy type 1

    Acta Neurologica Scandinavica

    Volume 132, Issue 1, July 2015, Pages: 49–58, J. A. Bertrand, S. Jean, L. Laberge, C. Gagnon, J. Mathieu, J. F. Gagnon and L. Richer

    Version of Record online : 11 DEC 2014, DOI: 10.1111/ane.12356

  13. Regional body composition and functional impairment in patients with myotonic dystrophy

    Muscle & Nerve

    Volume 44, Issue 4, October 2011, Pages: 503–508, Lelia Pruna, Jerome Chatelin, Veronique Pascal-Vigneron and Pierre Kaminsky

    Version of Record online : 8 AUG 2011, DOI: 10.1002/mus.22099

  14. Polyneuropathy in type 1 and type 2 diabetes: comparison of nerve conduction studies, thermal perception thresholds and intraepidermal nerve fibre densities

    Diabetes/Metabolism Research and Reviews

    Volume 26, Issue 2, February 2010, Pages: 100–106, Sissel Løseth, Svein I. Mellgren, Rolf Jorde, Sigurd Lindal and Erik Stålberg

    Version of Record online : 26 NOV 2009, DOI: 10.1002/dmrr.1049

  15. Sequential IL-23 and IL-17 and increased Mmp8 and Mmp14 expression characterize the progression of an experimental model of periodontal disease in type 1 diabetes

    Journal of Cellular Physiology

    Volume 227, Issue 6, June 2012, Pages: 2441–2450, Juliete A.F. Silva, Danilo L. Ferrucci, Luis A. Peroni, Patrícia G.S. Abrahão, Aline F. Salamene, Carlos Rossa-Junior, Hernandes F. Carvalho and Dagmar R. Stach-Machado

    Version of Record online : 24 FEB 2012, DOI: 10.1002/jcp.22979

  16. Dysphagia in duchenne muscular dystrophy versus myotonic dystrophy type 1

    Muscle & Nerve

    Volume 46, Issue 4, October 2012, Pages: 490–495, George Umemoto, Hirokazu Furuya, Akio Kitashima, Mitsuaki Sakai, Hajime Arahata and Toshihiro Kikuta

    Version of Record online : 13 SEP 2012, DOI: 10.1002/mus.23364

  17. You have free access to this content
    Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles

    Genes to Cells

    Volume 12, Issue 9, September 2007, Pages: 1035–1048, Ian Holt, Saloni Mittal, Denis Furling, Gillian S Butler-Browne, J. David Brook and Glenn E. Morris

    Version of Record online : 3 SEP 2007, DOI: 10.1111/j.1365-2443.2007.01112.x

  18. Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

    Annals of Neurology

    Volume 54, Issue 6, December 2003, Pages: 760–768, Ami Mankodi, Patana Teng-Umnuay, Matt Krym, Don Henderson, Maurice Swanson and Charles A. Thornton

    Version of Record online : 26 NOV 2003, DOI: 10.1002/ana.10763

  19. You have free access to this content
    Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2

    Obesity

    Volume 23, Issue 3, March 2015, Pages: 552–557, Spyridoula Maraka, Yogish C. Kudva, Todd A. Kellogg, Maria L. Collazo-Clavell and Manpreet S. Mundi

    Version of Record online : 22 JAN 2015, DOI: 10.1002/oby.20992

  20. Parent-reported multi-national study of the impact of congenital and childhood onset myotonic dystrophy

    Developmental Medicine & Child Neurology

    Nicholas E Johnson, Anne-Berit Ekstrom, Craig Campbell, Man Hung, Heather R Adams, Wei Chen, Elizabeth Luebbe, James Hilbert, Richard T Moxley III and Chad R Heatwole

    Version of Record online : 28 OCT 2015, DOI: 10.1111/dmcn.12948