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There are 16517 results for: content related to: Phase 2 trial of afatinib, an ErbB family blocker, in solid tumors genetically screened for target activation

  1. You have free access to this content
    Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer

    Cancer

    Volume 120, Issue 15, August 1, 2014, Pages: 2289–2298, Adrian G. Sacher, Pasi A. Jänne and Geoffrey R. Oxnard

    Version of Record online : 17 APR 2014, DOI: 10.1002/cncr.28723

  2. You have full text access to this OnlineOpen article
    A phase 2 trial of dacomitinib (PF-00299804), an oral, irreversible pan-HER (human epidermal growth factor receptor) inhibitor, in patients with advanced non–small cell lung cancer after failure of prior chemotherapy and erlotinib

    Cancer

    Volume 120, Issue 8, 15 April 2014, Pages: 1145–1154, Karen L. Reckamp, Giuseppe Giaccone, D. Ross Camidge, Shirish M. Gadgeel, Fadlo R. Khuri, Jeff A. Engelman, Marianna Koczywas, Arun Rajan, Alicyn K. Campbell, Diana Gernhardt, Ana Ruiz-Garcia, Stephen Letrent, Jane Liang, Ian Taylor, Joseph P. O'Connell and Pasi A. Jänne

    Version of Record online : 5 FEB 2014, DOI: 10.1002/cncr.28561

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    Association of epidermal growth factor receptor (EGFR) gene mutations with EGFR amplification in advanced non-small cell lung cancer

    Cancer Science

    Volume 99, Issue 12, December 2008, Pages: 2455–2460, Ryotaro Morinaga, Isamu Okamoto, Yoshihiko Fujita, Tokuzo Arao, Masaru Sekijima, Kazuto Nishio, Hiroyuki Ito, Masahiro Fukuoka, Jun-ichi Kadota and Kazuhiko Nakagawa

    Version of Record online : 16 OCT 2008, DOI: 10.1111/j.1349-7006.2008.00962.x

  4. The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target

    The Journal of Pathology

    Volume 223, Issue 3, February 2011, Pages: 336–346, Asem Shalaby, Nadège Presneau, Hongtao Ye, Dina Halai, Fitim Berisha, Bernadine Idowu, Andreas Leithner, Bernadette Liegl, Timothy RW Briggs, Krisztian Bacsi, Lars-Gunnar Kindblom, Nicholas Athanasou, Maria Fernanda Amary, Pancras CW Hogendoorn, Roberto Tirabosco and Adrienne M Flanagan

    Version of Record online : 10 DEC 2010, DOI: 10.1002/path.2818

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    Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer

    International Journal of Cancer

    Volume 121, Issue 5, 1 September 2007, Pages: 1162–1167, Junichi Soh, Shinichi Toyooka, Shuji Ichihara, Yoshiro Fujiwara, Katsuyuki Hotta, Hiroshi Suehisa, Naruyuki Kobayashi, Kouichi Ichimura, Keisuke Aoe, Motoi Aoe, Katsuyuki Kiura and Hiroshi Date

    Version of Record online : 8 MAY 2007, DOI: 10.1002/ijc.22818

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    Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: A prospective, single-institute study

    Cancer

    Volume 120, Issue 10, 15 May 2014, Pages: 1471–1481, Masakuni Serizawa, Yasuhiro Koh, Hirotsugu Kenmotsu, Mitsuhiro Isaka, Haruyasu Murakami, Hiroaki Akamatsu, Keita Mori, Masato Abe, Isamu Hayashi, Tetsuhiko Taira, Tomohiro Maniwa, Toshiaki Takahashi, Masahiro Endo, Takashi Nakajima, Yasuhisa Ohde and Nobuyuki Yamamoto

    Version of Record online : 3 APR 2014, DOI: 10.1002/cncr.28604

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    Pemetrexed versus erlotinib in pretreated patients with advanced non–small cell lung cancer: A Hellenic Oncology Research Group (HORG) randomized phase 3 study

    Cancer

    Volume 119, Issue 15, 1 August 2013, Pages: 2754–2764, Athanasios Karampeazis, Alexandra Voutsina, John Souglakos, Nikos Kentepozidis, Stelios Giassas, Charalambos Christofillakis, Athanasios Kotsakis, Pavlos Papakotoulas, Ageliki Rapti, Maria Agelidou, Sofia Agelaki, Lambros Vamvakas, George Samonis, Dimitris Mavroudis and Vassilis Georgoulias

    Version of Record online : 9 MAY 2013, DOI: 10.1002/cncr.28132

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    Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations

    Cancer

    Volume 120, Issue 14, 15 July 2014, Pages: 2090–2098, Youngjoo Lee, Geon Kook Lee, Yeon-Su Lee, Wenji Zhang, Jung-Ah Hwang, Byung-Ho Nam, Seok Hyun Kim, Joo-Hang Kim, Tak Yun, Ji-Youn Han, Heung Tae Kim and Jin Soo Lee

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28711

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    The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer

    Cancer

    Volume 121, Issue 8, April 15, 2015, Pages: E1–E6, Conor E. Steuer, Fadlo R. Khuri and Suresh S. Ramalingam

    Version of Record online : 17 DEC 2014, DOI: 10.1002/cncr.29139

  10. Impact of epidermal growth factor receptor protein and gene alteration on Taiwanese hepatocellular carcinomas

    Journal of Gastroenterology and Hepatology

    Volume 30, Issue 9, September 2015, Pages: 1397–1404, Yu-Hung Su, Kwai-Fong Ng, Ming-Chin Yu, Ting-Jung Wu, Ta-Sen Yeh, Wei-Chen Lee, Yong-Shiang Lin, Tsung-Han Hsieh, Chun-Yen Lin, Chau-Ting Yeh and Tse-Ching Chen

    Version of Record online : 27 JUL 2015, DOI: 10.1111/jgh.12944

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    Epidermal growth factor receptor exon 20 insertions in advanced lung adenocarcinomas: Clinical outcomes and response to erlotinib

    Cancer

    Volume 121, Issue 18, September 15, 2015, Pages: 3212–3220, Jarushka Naidoo, Camelia S. Sima, Katherine Rodriguez, Natalie Busby, Khedoudja Nafa, Marc Ladanyi, Gregory J. Riely, Mark G. Kris, Maria E. Arcila and Helena A. Yu

    Version of Record online : 10 JUN 2015, DOI: 10.1002/cncr.29493

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    EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis

    International Journal of Cancer

    Volume 121, Issue 8, 15 October 2007, Pages: 1729–1737, Zsuzsa Rákosy, Laura Vízkeleti, Szilvia Ecsedi, Zoltán Vokó, Ágnes Bégány, Márk Barok, Zsuzsa Krekk, Mónika Gallai, Zoltán Szentirmay, Róza Ádány and Margit Balázs

    Version of Record online : 26 JUN 2007, DOI: 10.1002/ijc.22928

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    The Bim deletion polymorphism clinical profile and its relation with tyrosine kinase inhibitor resistance in Chinese patients with non–small cell lung cancer

    Cancer

    Volume 120, Issue 15, August 1, 2014, Pages: 2299–2307, Mingchuan Zhao, Yishi Zhang, Weijing Cai, Jiayu Li, Fei Zhou, Ningning Cheng, Ruixin Ren, Chao Zhao, Xuefei Li, Shengxiang Ren, Caicun Zhou and Fred R. Hirsch

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28725

  14. HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status

    Histopathology

    Volume 63, Issue 3, September 2013, Pages: 378–392, Takafumi Nakano, Hidetaka Yamamoto, Kazuki Hashimoto, Sadafumi Tamiya, Hideki Shiratsuchi, Torahiko Nakashima, Ken-ichi Nishiyama, Yuichiro Higaki, Shizuo Komune and Yoshinao Oda

    Version of Record online : 16 JUL 2013, DOI: 10.1111/his.12183

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    Differences in driver genes between smoking-related and non–smoking-related lung cancer in the Chinese population

    Cancer

    Volume 121, Issue S17, September 1, 2015, Pages: 3069–3079, Lan-Ying Gou, Fei-Yu Niu, Yi-Long Wu and Wen-Zhao Zhong

    Version of Record online : 1 SEP 2015, DOI: 10.1002/cncr.29531

  16. EGFR expression and copy number changes in low T-stage oral squamous cell carcinomas

    Histopathology

    Volume 63, Issue 2, August 2013, Pages: 271–278, Matthias Rössle, Claudia S Weber, Lena Züllig, Nicole Graf, Wolfram Jochum, Sandro J Stöckli, Holger Moch and Gerhard F Huber

    Version of Record online : 13 JUN 2013, DOI: 10.1111/his.12175

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    Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

    Cancer Science

    Volume 98, Issue 12, December 2007, Pages: 1817–1824, Tetsuya Mitsudomi and Yasushi Yatabe

    Version of Record online : 20 SEP 2007, DOI: 10.1111/j.1349-7006.2007.00607.x

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    EGFR gene status in cytological samples of nonsmall cell lung carcinoma

    Cancer Cytopathology

    Volume 119, Issue 2, 25 April 2011, Pages: 80–91, Gilda da Cunha Santos, Mauro Ajaj Saieg, William Geddie and Natasha Leighl

    Version of Record online : 11 MAR 2011, DOI: 10.1002/cncy.20150

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    EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a second mutation or amplification

    Cancer Science

    Volume 97, Issue 8, August 2006, Pages: 753–759, Toshihiko Yokoyama, Masashi Kondo, Yasuhiro Goto, Takayuki Fukui, Hiromu Yoshioka, Kohei Yokoi, Hirotaka Osada, Kazuyoshi Imaizumi, Yoshinori Hasegawa, Kaoru Shimokata and Yoshitaka Sekido

    Version of Record online : 9 JUN 2006, DOI: 10.1111/j.1349-7006.2006.00233.x

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    Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium

    Cancer

    Volume 121, Issue 3, February 1, 2015, Pages: 448–456, Liza C. Villaruz, Mark A. Socinski, Shira Abberbock, Lynne D. Berry, Bruce E. Johnson, David J. Kwiatkowski, A. John Iafrate, Marileila Varella-Garcia, Wilbur A. Franklin, D. Ross Camidge, Lecia V. Sequist, Eric B. Haura, Mark Ladanyi, Brenda F. Kurland, Kelly Kugler, John D. Minna, Paul A. Bunn and Mark G. Kris

    Version of Record online : 1 OCT 2014, DOI: 10.1002/cncr.29042