Search Results

There are 17649 results for: content related to: Follow-up actions from positive results of in vitro genetic toxicity testing

  1. You have free access to this content
    International regulatory requirements for genotoxicity testing for pharmaceuticals used in human medicine, and their impurities and metabolites

    Environmental and Molecular Mutagenesis

    Volume 58, Issue 5, June 2017, Pages: 296–324, Sheila M. Galloway

    Version of Record online : 16 MAR 2017, DOI: 10.1002/em.22077

  2. Genetic Toxicology Testing Guidelines and Regulations

    Cancer Risk Assessment

    Lutz Müller, Hans-Jörg Martus, Pages: 238–271, 2010

    Published Online : 5 AUG 2010, DOI: 10.1002/9780470622728.ch10

  3. In vivo Genotoxicity Assays

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Andreas Hartmann, Krista L. Dobo and Hans-Jörg Martus

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse075

  4. New and emerging technologies for genetic toxicity testing

    Environmental and Molecular Mutagenesis

    Volume 52, Issue 3, April 2011, Pages: 205–223, Anthony M. Lynch, Jennifer C. Sasaki, Rosalie Elespuru, David Jacobson-Kram, Véronique Thybaud, Marlies De Boeck, Marilyn J. Aardema, Jiri Aubrecht, R. Daniel Benz, Stephen D. Dertinger, George R. Douglas, Paul A. White, Patricia A. Escobar, Albert Fornace Jr., Masamitsu Honma, Russell T. Naven, James F. Rusling, Robert H. Schiestl, Richard M. Walmsley, Eiji Yamamura, Jan van Benthem and James H. Kim

    Version of Record online : 25 AUG 2010, DOI: 10.1002/em.20614

  5. In Vivo Genotoxicity Assays

    Cancer Risk Assessment

    Ching-Hung Hsu, Todd Stedeford, Pages: 289–359, 2010

    Published Online : 5 AUG 2010, DOI: 10.1002/9780470622728.ch12

  6. Human Genotoxic Metabolites: Identification and Risk Management

    Genotoxic Impurities

    Krista Dobo, Don Walker, Andrew Teasdale, Pages: 151–167, 2011

    Published Online : 3 JAN 2011, DOI: 10.1002/9780470929377.ch6

  7. Genotoxicity

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse133

  8. Mutagenesis

    Standard Article

    General, Applied and Systems Toxicology

    Anthony Lynch

    Published Online : 15 DEC 2009, DOI: 10.1002/9780470744307.gat074

  9. Abstracts from the Environmental Mutagenesis and Genomics Society 46th Annual Meeting; September 26-30, 2015, New Orleans, Louisiana

    Environmental and Molecular Mutagenesis

    Volume 56, Issue S1, August 2015, Pages: S1–S91,

    Version of Record online : 21 AUG 2015, DOI: 10.1002/em.21969

  10. You have free access to this content
    Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites

    Environmental and Molecular Mutagenesis

    Volume 58, Issue 5, June 2017, Pages: 325–344, Ewan D. Booth, Paul J. Rawlinson, Priscila Maria Fagundes and Kevin A. Leiner

    Version of Record online : 22 MAR 2017, DOI: 10.1002/em.22084

  11. You have full text access to this Open Access content
    Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment

    EFSA Journal

    Volume 9, Issue 9, September 2011, EFSA Scientific Committee

    Version of Record online : 30 SEP 2011, DOI: 10.2903/j.efsa.2011.2379

  12. Genetic Toxicology Testing and its Relevance to Human Risk and Safety Evaluation

    Standard Article

    General, Applied and Systems Toxicology

    Elisabeth Lorge

    Published Online : 15 DEC 2009, DOI: 10.1002/9780470744307.gat076

  13. Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes

    Environmental and Molecular Mutagenesis

    Volume 47, Issue 5, June 2006, Pages: 362–390, Michael C. Cimino

    Version of Record online : 28 APR 2006, DOI: 10.1002/em.20216

  14. Miniaturized flow cytometry-based in vitro primary human lymphocyte micronucleus assay—validation study

    Environmental and Molecular Mutagenesis

    Volume 53, Issue 4, May 2012, Pages: 260–270, Magdalena Lukamowicz-Rajska, Micheline Kirsch-Volders, Willi Suter, Hansjoerg Martus and Azeddine Elhajouji

    Version of Record online : 19 MAR 2012, DOI: 10.1002/em.21690

  15. Genotoxicity

    Drug Safety Evaluation

    Shayne Cox Gad, Pages: 234–303, 2011

    Published Online : 16 AUG 2011, DOI: 10.1002/9780470464151.ch7

  16. In Vivo Genotoxicity Assays

    Preclinical Development Handbook: Toxicology

    Andreas Hartmann, Krista L. Dobo, Hans-Jörg Martus, Pages: 169–211, 2007

    Published Online : 27 AUG 2007, DOI: 10.1002/9780470249055.ch7

  17. Preclinical Safety Testing

    The Textbook of Pharmaceutical Medicine, 7th Edition

    Lutz Müller, Elisabeth Husar, Pages: 42–81, 2013

    Published Online : 25 APR 2013, DOI: 10.1002/9781118532331.ch3

  18. You have free access to this content
    How accurate is in vitro prediction of carcinogenicity?

    British Journal of Pharmacology

    Volume 162, Issue 6, March 2011, Pages: 1250–1258, Richard Maurice Walmsley and Nicholas Billinton

    Version of Record online : 22 FEB 2011, DOI: 10.1111/j.1476-5381.2010.01131.x

  19. You have free access to this content
    Genotoxicity testing approaches for the safety assessment of substances used in food contact materials prior to their authorization in the European Union

    Environmental and Molecular Mutagenesis

    Volume 58, Issue 5, June 2017, Pages: 361–374, Claudia Bolognesi, Anna F. Castoldi, Riccardo Crebelli, Eric Barthélémy, Daniela Maurici, Detlef Wölfle, Katharina Volk and Laurence Castle

    Version of Record online : 28 MAY 2017, DOI: 10.1002/em.22094

  20. Overview of mutation assays in transgenic mice for routine testing

    Environmental and Molecular Mutagenesis

    Volume 25, Issue 3, 1995, Pages: 218–230, N. J. Gorelick

    Version of Record online : 14 JUL 2006, DOI: 10.1002/em.2850250309