Search Results

There are 5076 results for: content related to: PINK1 function in health and disease

  1. You have full text access to this OnlineOpen article
    Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

    EMBO Molecular Medicine

    Volume 1, Issue 2, May 2009, Pages: 99–111, Vanessa A. Morais, Patrik Verstreken, Anne Roethig, Joél Smet, An Snellinx, Mieke Vanbrabant, Dominik Haddad, Christian Frezza, Wim Mandemakers, Daniela Vogt-Weisenhorn, Rudy Van Coster, Wolfgang Wurst, Luca Scorrano and Bart De Strooper

    Article first published online : 21 APR 2009, DOI: 10.1002/emmm.200900006

  2. Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1)

    Human Mutation

    Volume 33, Issue 10, October 2012, Pages: 1408–1422, Chou Hung Sim, Kipros Gabriel, Ryan D. Mills, Janetta G. Culvenor and Heung-Chin Cheng

    Article first published online : 5 JUL 2012, DOI: 10.1002/humu.22127

  3. You have free access to this content
    Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

    The EMBO Journal

    Volume 31, Issue 14, July 18, 2012, Pages: 3038–3062, Nicole Exner, Anne Kathrin Lutz, Christian Haass and Konstanze F Winklhofer

    Article first published online : 26 JUN 2012, DOI: 10.1038/emboj.2012.170

  4. You have full text access to this OnlineOpen article
    In a flurry of PINK, mitochondrial bioenergetics takes a leading role in Parkinson's disease

    EMBO Molecular Medicine

    Volume 1, Issue 2, May 2009, Pages: 81–84, Anne N. Murphy

    Article first published online : 8 MAY 2009, DOI: 10.1002/emmm.200900020

  5. You have free access to this content
    Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)

    Journal of Neurochemistry

    Volume 105, Issue 1, April 2008, Pages: 18–33, Ryan D. Mills, Chou Hung Sim, Su San Mok, Terrence D. Mulhern, Janetta G. Culvenor and Heung-Chin Cheng

    Article first published online : 22 JAN 2008, DOI: 10.1111/j.1471-4159.2008.05249.x

  6. You have free access to this content
    Phylogenetic and in silico structural analysis of the Parkinson disease-related kinase PINK1

    Human Mutation

    Volume 32, Issue 4, April 2011, Pages: 369–378, Fernando Cardona, Jose Vicente Sánchez-Mut, Hernán Dopazo and Jordi Pérez-Tur

    Article first published online : 15 MAR 2011, DOI: 10.1002/humu.21444

  7. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A

    Journal of Neurochemistry

    Volume 128, Issue 6, March 2014, Pages: 864–877, Ruben K. Dagda, Irene Pien, Ruth Wang, Jianhui Zhu, Kent Z. Q. Wang, Jason Callio, Tania Das Banerjee, Raul Y. Dagda and Charleen T. Chu

    Article first published online : 13 NOV 2013, DOI: 10.1111/jnc.12494

  8. You have free access to this content
    Balance is the challenge – The impact of mitochondrial dynamics in Parkinson’s disease

    European Journal of Clinical Investigation

    Volume 40, Issue 11, November 2010, Pages: 1048–1060, Lena F. Burbulla, Guido Krebiehl and Rejko Krüger

    Article first published online : 3 AUG 2010, DOI: 10.1111/j.1365-2362.2010.02354.x

  9. You have full text access to this OnlineOpen article
    PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease

    FEBS Journal

    Agne Kazlauskaite and Miratul M. K. Muqit

    Article first published online : 20 NOV 2014, DOI: 10.1111/febs.13127

  10. You have free access to this content
    The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

    Journal of Neurochemistry

    Volume 117, Issue 5, June 2011, Pages: 856–867, Cathrin Meissner, Holger Lorenz, Andreas Weihofen, Dennis J. Selkoe and Marius K. Lemberg

    Article first published online : 13 APR 2011, DOI: 10.1111/j.1471-4159.2011.07253.x

  11. You have free access to this content
    Characterization of PINK1 processing, stability, and subcellular localization

    Journal of Neurochemistry

    Volume 106, Issue 1, July 2008, Pages: 464–474, William Lin and Un Jung Kang

    Article first published online : 5 APR 2008, DOI: 10.1111/j.1471-4159.2008.05398.x

  12. You have full text access to this OnlineOpen article
    Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

    The EMBO Journal

    Volume 33, Issue 4, 18 February 2014, Pages: 341–355, Pontus Klein, Anne Kathrin Müller-Rischart, Elisa Motori, Cornelia Schönbauer, Frank Schnorrer, Konstanze F Winklhofer and Rüdiger Klein

    Article first published online : 29 JAN 2014, DOI: 10.1002/embj.201284290

    Corrected by:

    Corrigendum: Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

    Vol. 33, Issue 7, 779, Article first published online: 1 APR 2014

  13. You have free access to this content
    Poster Presentations

    Movement Disorders

    Volume 27, Issue S1, June 2012, Pages: S1–S523,

    Article first published online : 19 JUN 2012, DOI: 10.1002/mds.25051

  14. You have free access to this content
    Regulation of PINK1 by NR2B-containing NMDA receptors in ischemic neuronal injury

    Journal of Neurochemistry

    Volume 111, Issue 5, December 2009, Pages: 1149–1160, Yuexin Shan, Baosong Liu, Lijun Li, Ning Chang, Lei Li, Hanbin Wang, Dianshi Wang, Hua Feng, Carol Cheung, Mingxia Liao, Tianyuan Cui, Shuzo Sugita and Qi Wan

    Article first published online : 23 SEP 2009, DOI: 10.1111/j.1471-4159.2009.06398.x

  15. You have free access to this content
    The Parkinson's disease-associated gene PINK1 protects neurons from ischemic damage by decreasing mitochondrial translocation of the fission promoter Drp1

    Journal of Neurochemistry

    Volume 127, Issue 5, December 2013, Pages: 711–722, Yanxin Zhao, Fangzhe Chen, Shufen Chen, Xueyuan Liu, Mei Cui and Qiang Dong

    Article first published online : 30 JUN 2013, DOI: 10.1111/jnc.12340

  16. Therapeutic strategies in Parkinson's disease: what we have learned from animal models

    Annals of the New York Academy of Sciences

    Jorge S. Valadas, Melissa Vos and Patrik Verstreken

    Article first published online : 16 DEC 2014, DOI: 10.1111/nyas.12577

  17. You have full text access to this OnlineOpen article
    Unravelling mitochondrial pathways to Parkinson's disease

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1943–1957, I Celardo, L M Martins and S Gandhi

    Article first published online : 28 MAR 2014, DOI: 10.1111/bph.12433

  18. You have free access to this content
    Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

    Journal of Neurochemistry

    Volume 98, Issue 1, July 2006, Pages: 156–169, Miratul M. K. Muqit, Patrick M. Abou-Sleiman, Adrian T. Saurin, Kirsten Harvey, Sonia Gandhi, Emma Deas, Simon Eaton, Martin D. Payne Smith, Kerrie Venner, Antoni Matilla, Daniel G. Healy, William P. Gilks, Andrew J. Lees, Janice Holton, Tamas Revesz, Peter J. Parker, Robert J. Harvey, Nicholas W. Wood and David S. Latchman

    Article first published online : 18 MAY 2006, DOI: 10.1111/j.1471-4159.2006.03845.x

  19. Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function

    European Journal of Neuroscience

    Volume 31, Issue 4, February 2010, Pages: 623–633, Yanwei Xi, Joel Ryan, Sandra Noble, Man Yu, Ayse E. Yilbas and Marc Ekker

    Article first published online : 5 FEB 2010, DOI: 10.1111/j.1460-9568.2010.07091.x

  20. You have free access to this content
    Zebrafish Parla- and Parlb-deficiency affects dopaminergic neuron patterning and embryonic survival

    Journal of Neurochemistry

    Volume 122, Issue 1, July 2012, Pages: 196–207, Sandra Noble, Abid Ismail, Rafael Godoy, Yanwei Xi and Marc Ekker

    Article first published online : 9 MAY 2012, DOI: 10.1111/j.1471-4159.2012.07758.x