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There are 8849 results for: content related to: Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

  1. You have full text access to this OnlineOpen article
    Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

    EMBO Molecular Medicine

    Volume 2, Issue 11, November 2010, Pages: 440–457, Frédéric Varnat, Irene Siegl-Cachedenier, Monica Malerba, Pascal Gervaz and Ariel Ruiz i Altaba

    Version of Record online : 13 OCT 2010, DOI: 10.1002/emmm.201000098

  2. You have full text access to this OnlineOpen article
    Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

    EMBO Molecular Medicine

    Volume 4, Issue 3, March 2012, Pages: 218–233, Markus Eberl, Stefan Klingler, Doris Mangelberger, Andrea Loipetzberger, Helene Damhofer, Kerstin Zoidl, Harald Schnidar, Hendrik Hache, Hans-Christian Bauer, Flavio Solca, Cornelia Hauser-Kronberger, Alexandre N. Ermilov, Monique E. Verhaegen, Christopher K. Bichakjian, Andrzej A. Dlugosz, Wilfried Nietfeld, Maria Sibilia, Hans Lehrach, Christoph Wierling and Fritz Aberger

    Version of Record online : 1 FEB 2012, DOI: 10.1002/emmm.201100201

  3. You have full text access to this OnlineOpen article
    GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 488–508, Hira Lal Goel, Bryan Pursell, Cheng Chang, Leslie M. Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W. Vander Kooi, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser and Arthur M. Mercurio

    Version of Record online : 21 FEB 2013, DOI: 10.1002/emmm.201202078

  4. You have full text access to this OnlineOpen article
    A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

    The EMBO Journal

    Volume 28, Issue 6, March 18, 2009, Pages: 663–676, Barbara Stecca and Ariel Ruiz i Altaba

    Version of Record online : 12 FEB 2009, DOI: 10.1038/emboj.2009.16

  5. You have free access to this content
    HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells

    STEM CELLS

    Volume 30, Issue 9, September 2012, Pages: 1808–1818, Roberta Santini, Maria C. Vinci, Silvia Pandolfi, Junia Y. Penachioni, Valentina Montagnani, Biagio Olivito, Riccardo Gattai, Nicola Pimpinelli, Gianni Gerlini, Lorenzo Borgognoni and Barbara Stecca

    Version of Record online : 20 AUG 2012, DOI: 10.1002/stem.1160

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    Brain as a paradigm of organ growth: Hedgehog–Gli signaling in neural stem cells and brain tumors

    Journal of Neurobiology

    Volume 64, Issue 4, 15 September 2005, Pages: 476–490, Barbara Stecca and Ariel Ruiz i Altaba

    Version of Record online : 22 JUL 2005, DOI: 10.1002/neu.20160

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    A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells

    FEBS Letters

    Volume 587, Issue 6, March 18, 2013, Pages: 631–638, Jianchao Gao, Ammad Aslam Khan, Takashi Shimokawa, Jun Zhan, Staffan Strömblad, Weigang Fang and Hongquan Zhang

    Version of Record online : 18 JAN 2013, DOI: 10.1016/j.febslet.2012.12.028

  8. You have free access to this content
    Hedgehog Signaling Regulates Brain Tumor-Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas

    STEM CELLS

    Volume 26, Issue 12, December 2008, Pages: 3018–3026, Qijin Xu, Xiangpeng Yuan, Gentao Liu, Keith L. Black and John S. Yu

    Version of Record online : 11 SEP 2008, DOI: 10.1634/stemcells.2008-0459

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    Tumor suppressor protein VHL inhibits Hedgehog–Gli activation through suppression of Gli1 nuclear localization

    FEBS Letters

    Volume 587, Issue 7, April 02, 2013, Pages: 826–832, Hyun Kook Cho, So Young Kim, Kook Hwan Kim, Hyeong Hoe Kim and JaeHun Cheong

    Version of Record online : 8 FEB 2013, DOI: 10.1016/j.febslet.2013.01.050

  10. You have full text access to this Open Access content
    Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

    Cancer Science

    Volume 99, Issue 7, July 2008, Pages: 1377–1384, Shuntaro Nagai, Masafumi Nakamura, Kosuke Yanai, Junji Wada, Takashi Akiyoshi, Hiroshi Nakashima, Kenoki Ohuchida, Norihiro Sato, Masao Tanaka and Mitsuo Katano

    Version of Record online : 11 APR 2008, DOI: 10.1111/j.1349-7006.2008.00822.x

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    NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

    The EMBO Journal

    Volume 29, Issue 15, August 4, 2010, Pages: 2659–2674, Marie Zbinden, Arnaud Duquet, Aiala Lorente-Trigos, Sandra-Nadia Ngwabyt, Isabel Borges and Ariel Ruiz i Altaba

    Version of Record online : 25 JUN 2010, DOI: 10.1038/emboj.2010.137

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    In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

    International Journal of Cancer

    Volume 131, Issue 2, 15 July 2012, Pages: E33–E44, Pietro Ferruzzi, Federica Mennillo, Antonella De Rosa, Cinzia Giordano, Marco Rossi, Giovanni Benedetti, Roberta Magrini, Gal.la Pericot Mohr, Vincenzo Miragliotta, Letizia Magnoni, Elisa Mori, Russell Thomas, Patrizia Tunici and Annette Bakker

    Version of Record online : 31 JAN 2012, DOI: 10.1002/ijc.27349

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    Sonic Hedgehog signaling in the mammalian brain

    Journal of Neurochemistry

    Volume 113, Issue 3, May 2010, Pages: 576–590, Elisabeth Traiffort, Elodie Angot and Martial Ruat

    Version of Record online : 10 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06642.x

  14. The hedgehog signaling network

    American Journal of Medical Genetics Part A

    Volume 123A, Issue 1, November 15, 2003, Pages: 5–28, M. Michael Cohen, Jr.

    Version of Record online : 19 SEP 2003, DOI: 10.1002/ajmg.a.20495

  15. You have full text access to this OnlineOpen article
    Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors

    The EMBO Journal

    Volume 34, Issue 2, 14 January 2015, Pages: 200–217, Paola Infante, Mattia Mori, Romina Alfonsi, Francesca Ghirga, Federica Aiello, Sara Toscano, Cinzia Ingallina, Mariangela Siler, Danilo Cucchi, Agnese Po, Evelina Miele, Davide D'Amico, Gianluca Canettieri, Enrico De Smaele, Elisabetta Ferretti, Isabella Screpanti, Gloria Uccello Barretta, Maurizio Botta, Bruno Botta, Alberto Gulino and Lucia Di Marcotullio

    Version of Record online : 4 DEC 2014, DOI: 10.15252/embj.201489213

  16. Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells

    The Journal of Pathology

    Volume 225, Issue 4, December 2011, Pages: 525–534, David W Chan, Vincent WS Liu, Ling Yang Leung, Kwok Ming Yao, Karen KL Chan, Annie NY Cheung and Hextan YS Ngan

    Version of Record online : 10 JUN 2011, DOI: 10.1002/path.2901

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    Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus

    International Journal of Cancer

    Volume 125, Issue 5, 1 September 2009, Pages: 1212–1221, Noriyuki Isohata, Kazuhiko Aoyagi, Tomoko Mabuchi, Hiroyuki Daiko, Masahide Fukaya, Hiroyuki Ohta, Kenji Ogawa, Teruhiko Yoshida and Hiroki Sasaki

    Version of Record online : 27 FEB 2009, DOI: 10.1002/ijc.24400

  18. You have full text access to this OnlineOpen article
    Crosstalk between TGF-β and hedgehog signaling in cancer

    FEBS Letters

    Volume 586, Issue 14, July 04, 2012, Pages: 2016–2025, Delphine Javelaud, Marie-Jeanne Pierrat and Alain Mauviel

    Version of Record online : 15 MAY 2012, DOI: 10.1016/j.febslet.2012.05.011

  19. Hedgehog signaling pathway is a possible therapeutic target for gastric cancer

    Journal of Surgical Oncology

    Volume 95, Issue 1, 1 January 2007, Pages: 55–62, Kosuke Yanai, Shuntaro Nagai, Junji Wada, Naoki Yamanaka, Masafumi Nakamura, Nobuhiro Torata, Hirokazu Noshiro, Masazumi Tsuneyoshi, Masao Tanaka and Mitsuo Katano

    Version of Record online : 27 DEC 2006, DOI: 10.1002/jso.20606

  20. β1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1

    Journal of Cellular Physiology

    Volume 224, Issue 1, July 2010, Pages: 210–217, Hira Lal Goel, Jean M. Underwood, Jeffrey A. Nickerson, Chung-Cheng Hsieh and Lucia R. Languino

    Version of Record online : 23 MAR 2010, DOI: 10.1002/jcp.22116