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There are 131379 results for: content related to: Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

  1. Predictive Tumor Biomarkers for EGFR Inhibitors

    Lung Cancer, Fourth Edition

    Lucia Kim, Geoffrey Liu, Ming-Sound Tsao, Pages: 435–453, 2014

    Published Online : 4 APR 2014, DOI: 10.1002/9781118468791.ch28

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    Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations

    Cancer

    Volume 120, Issue 14, 15 July 2014, Pages: 2090–2098, Youngjoo Lee, Geon Kook Lee, Yeon-Su Lee, Wenji Zhang, Jung-Ah Hwang, Byung-Ho Nam, Seok Hyun Kim, Joo-Hang Kim, Tak Yun, Ji-Youn Han, Heung Tae Kim and Jin Soo Lee

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28711

  3. You have full text access to this OnlineOpen article
    Clinical outcome of epidermal growth factor receptor-tyrosine kinase inhibitors therapy for patients with overlapping kirsten rat sarcoma 2 viral oncogene homolog and epidermal growth factor receptor gene mutations

    Thoracic Cancer

    Volume 7, Issue 1, January 2016, Pages: 24–31, Hong Zhang, Hua Bai, Xiaodan Yang, Jia Zhong, Tongtong An, Jun Zhao and Jie Wang

    Version of Record online : 11 JUN 2015, DOI: 10.1111/1759-7714.12266

  4. You have full text access to this OnlineOpen article
    A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis

    EMBO Molecular Medicine

    Volume 4, Issue 3, March 2012, Pages: 206–217, Olga Grechukhina, Rafaella Petracco, Shota Popkhadze, Efi Massasa, Trupti Paranjape, Elcie Chan, Idhaliz Flores, Joanne B. Weidhaas and Hugh S. Taylor

    Version of Record online : 3 FEB 2012, DOI: 10.1002/emmm.201100200

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    Gene signature driving invasive mucinous adenocarcinoma of the lung

    EMBO Molecular Medicine

    Volume 9, Issue 4, April 2017, Pages: 462–481, Minzhe Guo, Koichi Tomoshige, Michael Meister, Thomas Muley, Takuya Fukazawa, Tomoshi Tsuchiya, Rebekah Karns, Arne Warth, Iris M Fink-Baldauf, Takeshi Nagayasu, Yoshio Naomoto, Yan Xu, Marcus A Mall and Yutaka Maeda

    Version of Record online : 2 MAR 2017, DOI: 10.15252/emmm.201606711

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    Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer

    Cancer

    Volume 120, Issue 15, August 1, 2014, Pages: 2289–2298, Adrian G. Sacher, Pasi A. Jänne and Geoffrey R. Oxnard

    Version of Record online : 17 APR 2014, DOI: 10.1002/cncr.28723

  7. Detection of low-level EGFR T790M mutation in lung cancer tissues

    APMIS

    Volume 119, Issue 7, July 2011, Pages: 403–411, JI EUN OH, CHANG HYEOK AN, NAM JIN YOO and SUG HYUNG LEE

    Version of Record online : 13 MAY 2011, DOI: 10.1111/j.1600-0463.2011.02738.x

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    Not just gRASping at flaws: Finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers

    Cancer Science

    Volume 105, Issue 5, May 2014, Pages: 499–505, Hiromichi Ebi, Anthony C. Faber, Jeffrey A. Engelman and Seiji Yano

    Version of Record online : 26 MAR 2014, DOI: 10.1111/cas.12383

  9. Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways

    Journal of Cellular Physiology

    Volume 226, Issue 11, November 2011, Pages: 2762–2781, James A. McCubrey, Linda S. Steelman, C. Ruth Kempf, William H. Chappell, Stephen L. Abrams, Franca Stivala, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Jörg Bäsecke, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Giuseppe Montalto, Melchiorre Cervello, Lucio Cocco and Alberto M. Martelli

    Version of Record online : 24 AUG 2011, DOI: 10.1002/jcp.22647

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    Epidermal growth factor receptor mutation-guided treatment for lung cancers: Where are we now?

    Thoracic Cancer

    Volume 2, Issue 1, February 2011, Pages: 1–6, Zengliu Su

    Version of Record online : 1 FEB 2011, DOI: 10.1111/j.1759-7714.2010.00035.x

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    Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas

    Cancer

    Volume 119, Issue 2, 15 January 2013, Pages: 356–362, Melissa L. Johnson, Camelia S. Sima, Jamie Chaft, Paul K. Paik, William Pao, Mark G. Kris, Marc Ladanyi and Gregory J. Riely

    Version of Record online : 18 JUL 2012, DOI: 10.1002/cncr.27730

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    OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination

    EMBO Molecular Medicine

    Volume 8, Issue 3, March 2016, Pages: 288–303, Maria Francesca Baietti, Michal Simicek, Layka Abbasi Asbagh, Enrico Radaelli, Sam Lievens, Jonathan Crowther, Mikhail Steklov, Vasily N Aushev, David Martínez García, Jan Tavernier and Anna A Sablina

    Version of Record online : 8 FEB 2016, DOI: 10.15252/emmm.201505972

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    The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer

    Cancer

    Volume 121, Issue 8, April 15, 2015, Pages: E1–E6, Conor E. Steuer, Fadlo R. Khuri and Suresh S. Ramalingam

    Version of Record online : 17 DEC 2014, DOI: 10.1002/cncr.29139

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    Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

    Cancer Science

    Volume 98, Issue 12, December 2007, Pages: 1817–1824, Tetsuya Mitsudomi and Yasushi Yatabe

    Version of Record online : 20 SEP 2007, DOI: 10.1111/j.1349-7006.2007.00607.x

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    ALK-positive non–small cell lung cancer: Mechanisms of resistance and emerging treatment options

    Cancer

    Volume 120, Issue 16, August 15, 2014, Pages: 2392–2402, Conor E. Steuer and Suresh S. Ramalingam

    Version of Record online : 22 MAY 2014, DOI: 10.1002/cncr.28597

  16. You have full text access to this OnlineOpen article
    Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

    Clinical Pharmacology & Therapeutics

    Volume 93, Issue 3, March 2013, Pages: 252–259, D Gonzalez de Castro, P A Clarke, B Al-Lazikani and P Workman

    Version of Record online : 7 DEC 2012, DOI: 10.1038/clpt.2012.237

  17. Mechanisms of Resistance to Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer

    Lung Cancer, Fourth Edition

    Jack A. Roth, Waun Ki Hong, Ritsuko U. Komaki, Anne S. Tsao, Joe Y. Chang, Shanda H. Blackmon, Pages: 421–434, 2014

    Published Online : 4 APR 2014, DOI: 10.1002/9781118468791.ch27

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    Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer

    Molecular Oncology

    Volume 6, Issue 1, February 2012, Pages: 15–26, Rodrigo Dienstmann, Sara De Dosso, Enriqueta Felip, Josep Tabernero

    Version of Record online : 6 DEC 2011, DOI: 10.1016/j.molonc.2011.11.009

  19. Pharmacogenetic tests in cancer chemotherapy: what physicians should know for clinical application

    The Journal of Pathology

    Volume 223, Issue 1, January 2011, Pages: 15–27, Soo-Youn Lee and Howard L McLeod

    Version of Record online : 3 SEP 2010, DOI: 10.1002/path.2766

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    Genetically informed lung cancer medicine

    The Journal of Pathology

    Volume 223, Issue 2, January 2011, Pages: 231–241, William Pao, A John Iafrate and Zengliu Su

    Version of Record online : 25 OCT 2010, DOI: 10.1002/path.2788