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There are 3081 results for: content related to: Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

  1. You have full text access to this OnlineOpen article
    Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

    EMBO Molecular Medicine

    Volume 1, Issue 6-7, September/October 2009, Pages: 338–351, Frédéric Varnat, Arnaud Duquet, Monica Malerba, Marie Zbinden, Christophe Mas, Pascal Gervaz and Ariel Ruiz i Altaba

    Article first published online : 27 AUG 2009, DOI: 10.1002/emmm.200900039

  2. You have full text access to this OnlineOpen article
    A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

    The EMBO Journal

    Volume 28, Issue 6, March 18, 2009, Pages: 663–676, Barbara Stecca and Ariel Ruiz i Altaba

    Article first published online : 12 FEB 2009, DOI: 10.1038/emboj.2009.16

  3. You have free access to this content
    NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

    The EMBO Journal

    Volume 29, Issue 15, August 4, 2010, Pages: 2659–2674, Marie Zbinden, Arnaud Duquet, Aiala Lorente-Trigos, Sandra-Nadia Ngwabyt, Isabel Borges and Ariel Ruiz i Altaba

    Article first published online : 25 JUN 2010, DOI: 10.1038/emboj.2010.137

  4. You have full text access to this OnlineOpen article
    Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

    EMBO Molecular Medicine

    Volume 4, Issue 3, March 2012, Pages: 218–233, Markus Eberl, Stefan Klingler, Doris Mangelberger, Andrea Loipetzberger, Helene Damhofer, Kerstin Zoidl, Harald Schnidar, Hendrik Hache, Hans-Christian Bauer, Flavio Solca, Cornelia Hauser-Kronberger, Alexandre N. Ermilov, Monique E. Verhaegen, Christopher K. Bichakjian, Andrzej A. Dlugosz, Wilfried Nietfeld, Maria Sibilia, Hans Lehrach, Christoph Wierling and Fritz Aberger

    Article first published online : 1 FEB 2012, DOI: 10.1002/emmm.201100201

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    Gli1 Induces G2/M Arrest and Apoptosis in Hippocampal but Not Tumor-Derived Neural Stem Cells


    Volume 26, Issue 4, April 2008, Pages: 1027–1036, Katherine E. Galvin, Hong Ye, Derek J. Erstad, Rod Feddersen and Cynthia Wetmore

    Article first published online : 14 FEB 2008, DOI: 10.1634/stemcells.2007-0879

  6. Naturally Occurring Small-Molecule Inhibitors of Hedgehog/GLI-Mediated Transcription


    Volume 9, Issue 7, May 5, 2008, Pages: 1082–1092, Takahiro Hosoya, Midori A. Arai, Takashi Koyano, Thaworn Kowithayakorn and Masami Ishibashi

    Article first published online : 20 MAR 2008, DOI: 10.1002/cbic.200700511

  7. You have full text access to this OnlineOpen article
    Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors

    The EMBO Journal

    Volume 34, Issue 2, 14 January 2015, Pages: 200–217, Paola Infante, Mattia Mori, Romina Alfonsi, Francesca Ghirga, Federica Aiello, Sara Toscano, Cinzia Ingallina, Mariangela Siler, Danilo Cucchi, Agnese Po, Evelina Miele, Davide D'Amico, Gianluca Canettieri, Enrico De Smaele, Elisabetta Ferretti, Isabella Screpanti, Gloria Uccello Barretta, Maurizio Botta, Bruno Botta, Alberto Gulino and Lucia Di Marcotullio

    Article first published online : 4 DEC 2014, DOI: 10.15252/embj.201489213

  8. Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells

    Journal of Cellular Physiology

    Volume 226, Issue 4, April 2011, Pages: 1118–1127, Antony Hsieh, Ron Ellsworth and David Hsieh

    Article first published online : 25 JAN 2011, DOI: 10.1002/jcp.22433

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    HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells


    Volume 30, Issue 9, September 2012, Pages: 1808–1818, Roberta Santini, Maria C. Vinci, Silvia Pandolfi, Junia Y. Penachioni, Valentina Montagnani, Biagio Olivito, Riccardo Gattai, Nicola Pimpinelli, Gianni Gerlini, Lorenzo Borgognoni and Barbara Stecca

    Article first published online : 20 AUG 2012, DOI: 10.1002/stem.1160

  10. You have full text access to this OnlineOpen article
    Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma

    Journal of Cellular and Molecular Medicine

    Yi-Lin Yang, Jian Ni, Ping-Chih Hsu, Jian-Hua Mao, David Hsieh, Angela Xu, Geraldine Chan, Alfred Au, Zhidong Xu, David M. Jablons and Liang You

    Article first published online : 27 JUL 2015, DOI: 10.1111/jcmm.12620

  11. You have full text access to this OnlineOpen article
    GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 488–508, Hira Lal Goel, Bryan Pursell, Cheng Chang, Leslie M. Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W. Vander Kooi, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser and Arthur M. Mercurio

    Article first published online : 21 FEB 2013, DOI: 10.1002/emmm.201202078

  12. Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons

    Journal of Comparative Neurology

    Volume 519, Issue 15, 15 October 2011, Pages: 3001–3018, Lindsay Hayes, Zhiwei Zhang, Paul Albert, Mark Zervas and Sohyun Ahn

    Article first published online : 10 AUG 2011, DOI: 10.1002/cne.22711

  13. Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: A report from the Children's Oncology Group

    Pediatric Blood & Cancer

    Volume 57, Issue 6, 1 December 2011, Pages: 930–938, Joseph G. Pressey, James R. Anderson, David K. Crossman, James C. Lynch and Frederic G. Barr

    Article first published online : 25 MAY 2011, DOI: 10.1002/pbc.23174

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    Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

    International Journal of Cancer

    Volume 124, Issue 1, 1 January 2009, Pages: 109–119, Joon Won Yoon, Richard Gilbertson, Stephen Iannaccone, Philip Iannaccone and David Walterhouse

    Article first published online : 15 OCT 2008, DOI: 10.1002/ijc.23929

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    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo

    CNS Neuroscience & Therapeutics

    Volume 19, Issue 12, December 2013, Pages: 926–936, Wen-Zhong Du, Yan Feng, Xiao-Feng Wang, Xing-Yin Piao, Yu-Qiong Cui, Ling-Chao Chen, Xu-Hui Lei, Xu Sun, Xing Liu, Han-Bing Wang, Xian-Feng Li, Dong-Bo Yang, Ying Sun, Zhe-Feng Zhao, Tao Jiang, Yong-Li Li and Chuan-Lu Jiang

    Article first published online : 25 OCT 2013, DOI: 10.1111/cns.12163

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    Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer

    International Journal of Cancer

    Volume 129, Issue 2, 15 July 2011, Pages: 275–284, Lingyun Wei and Zhifei Xu

    Article first published online : 3 NOV 2010, DOI: 10.1002/ijc.25673

  17. Gli1 is not required for Pdgfrα expression during mouse embryonic development


    Volume 73, Issue 2-3, March 2005, Pages: 109–119, Xiao-Qun Zhang, Gijs B Afink, Xin-Rong Hu, Karin Forsberg-Nilsson and Monica Nistér

    Article first published online : 1 APR 2005, DOI: 10.1111/j.1432-0436.2005.07302003.x

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    Hedgehog Signaling Regulates Brain Tumor-Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas


    Volume 26, Issue 12, December 2008, Pages: 3018–3026, Qijin Xu, Xiangpeng Yuan, Gentao Liu, Keith L. Black and John S. Yu

    Article first published online : 11 SEP 2008, DOI: 10.1634/stemcells.2008-0459

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    In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

    International Journal of Cancer

    Volume 131, Issue 2, 15 July 2012, Pages: E33–E44, Pietro Ferruzzi, Federica Mennillo, Antonella De Rosa, Cinzia Giordano, Marco Rossi, Giovanni Benedetti, Roberta Magrini, Pericot Mohr, Vincenzo Miragliotta, Letizia Magnoni, Elisa Mori, Russell Thomas, Patrizia Tunici and Annette Bakker

    Article first published online : 31 JAN 2012, DOI: 10.1002/ijc.27349

  20. Hh-Gli signaling pathway activity in oral and oropharyngeal squamous cell carcinoma

    Head & Neck

    Volume 34, Issue 1, January 2012, Pages: 104–112, Dinko Leovic, Maja Sabol, Petar Ozretic, Vesna Musani, Diana Car, Ksenija Marjanovic, Vedran Zubcic, Ivan Sabol, Miroslav Sikora, Magdalena Grce, Ljubica Glavas-Obrovac and Sonja Levanat

    Article first published online : 11 APR 2011, DOI: 10.1002/hed.21696