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There are 7266 results for: content related to: Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

  1. You have full text access to this OnlineOpen article
    Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

    EMBO Molecular Medicine

    Volume 1, Issue 6-7, September/October 2009, Pages: 338–351, Frédéric Varnat, Arnaud Duquet, Monica Malerba, Marie Zbinden, Christophe Mas, Pascal Gervaz and Ariel Ruiz i Altaba

    Version of Record online : 27 AUG 2009, DOI: 10.1002/emmm.200900039

  2. You have free access to this content
    Progenitors of Secondary Crest Myofibroblasts Are Developmentally Committed in Early Lung Mesoderm


    Volume 33, Issue 3, March 2015, Pages: 999–1012, Changgong Li, Min Li, Sha Li, Yiming Xing, Chang-Yo Yang, Aimin Li, Zea Borok, Stijn De Langhe and Parviz Minoo

    Version of Record online : 17 FEB 2015, DOI: 10.1002/stem.1911

  3. You have full text access to this OnlineOpen article
    A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

    The EMBO Journal

    Volume 28, Issue 6, March 18, 2009, Pages: 663–676, Barbara Stecca and Ariel Ruiz i Altaba

    Version of Record online : 12 FEB 2009, DOI: 10.1038/emboj.2009.16

  4. You have full text access to this OnlineOpen article
    GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 488–508, Hira Lal Goel, Bryan Pursell, Cheng Chang, Leslie M. Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W. Vander Kooi, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser and Arthur M. Mercurio

    Version of Record online : 21 FEB 2013, DOI: 10.1002/emmm.201202078

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    Hedgehog Signaling Regulates Brain Tumor-Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas


    Volume 26, Issue 12, December 2008, Pages: 3018–3026, Qijin Xu, Xiangpeng Yuan, Gentao Liu, Keith L. Black and John S. Yu

    Version of Record online : 11 SEP 2008, DOI: 10.1634/stemcells.2008-0459

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    Tumor suppressor protein VHL inhibits Hedgehog–Gli activation through suppression of Gli1 nuclear localization

    FEBS Letters

    Volume 587, Issue 7, April 02, 2013, Pages: 826–832, Hyun Kook Cho, So Young Kim, Kook Hwan Kim, Hyeong Hoe Kim and JaeHun Cheong

    Version of Record online : 8 FEB 2013, DOI: 10.1016/j.febslet.2013.01.050

  7. You have full text access to this OnlineOpen article
    Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

    EMBO Molecular Medicine

    Volume 4, Issue 3, March 2012, Pages: 218–233, Markus Eberl, Stefan Klingler, Doris Mangelberger, Andrea Loipetzberger, Helene Damhofer, Kerstin Zoidl, Harald Schnidar, Hendrik Hache, Hans-Christian Bauer, Flavio Solca, Cornelia Hauser-Kronberger, Alexandre N. Ermilov, Monique E. Verhaegen, Christopher K. Bichakjian, Andrzej A. Dlugosz, Wilfried Nietfeld, Maria Sibilia, Hans Lehrach, Christoph Wierling and Fritz Aberger

    Version of Record online : 1 FEB 2012, DOI: 10.1002/emmm.201100201

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    Gli1 Induces G2/M Arrest and Apoptosis in Hippocampal but Not Tumor-Derived Neural Stem Cells


    Volume 26, Issue 4, April 2008, Pages: 1027–1036, Katherine E. Galvin, Hong Ye, Derek J. Erstad, Rod Feddersen and Cynthia Wetmore

    Version of Record online : 14 FEB 2008, DOI: 10.1634/stemcells.2007-0879

  9. Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms


    Volume 73, Issue 8, October 2005, Pages: 397–405, Paul C. Barnfield, Xiaoyun Zhang, Vijitha Thanabalasingham, Minoru Yoshida and Chi-chung Hui

    Version of Record online : 9 OCT 2008, DOI: 10.1111/j.1432-0436.2005.00042.x

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    HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells


    Volume 30, Issue 9, September 2012, Pages: 1808–1818, Roberta Santini, Maria C. Vinci, Silvia Pandolfi, Junia Y. Penachioni, Valentina Montagnani, Biagio Olivito, Riccardo Gattai, Nicola Pimpinelli, Gianni Gerlini, Lorenzo Borgognoni and Barbara Stecca

    Version of Record online : 20 AUG 2012, DOI: 10.1002/stem.1160

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    Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 10, October 2015, Pages: 2385–2396, Yi-Lin Yang, Jian Ni, Ping-Chih Hsu, Jian-Hua Mao, David Hsieh, Angela Xu, Geraldine Chan, Alfred Au, Zhidong Xu, David M. Jablons and Liang You

    Version of Record online : 27 JUL 2015, DOI: 10.1111/jcmm.12620

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    Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors

    The EMBO Journal

    Volume 34, Issue 2, 14 January 2015, Pages: 200–217, Paola Infante, Mattia Mori, Romina Alfonsi, Francesca Ghirga, Federica Aiello, Sara Toscano, Cinzia Ingallina, Mariangela Siler, Danilo Cucchi, Agnese Po, Evelina Miele, Davide D'Amico, Gianluca Canettieri, Enrico De Smaele, Elisabetta Ferretti, Isabella Screpanti, Gloria Uccello Barretta, Maurizio Botta, Bruno Botta, Alberto Gulino and Lucia Di Marcotullio

    Version of Record online : 4 DEC 2014, DOI: 10.15252/embj.201489213

  13. Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells

    The Journal of Pathology

    Volume 225, Issue 4, December 2011, Pages: 525–534, David W Chan, Vincent WS Liu, Ling Yang Leung, Kwok Ming Yao, Karen KL Chan, Annie NY Cheung and Hextan YS Ngan

    Version of Record online : 10 JUN 2011, DOI: 10.1002/path.2901

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    A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells

    FEBS Letters

    Volume 587, Issue 6, March 18, 2013, Pages: 631–638, Jianchao Gao, Ammad Aslam Khan, Takashi Shimokawa, Jun Zhan, Staffan Strömblad, Weigang Fang and Hongquan Zhang

    Version of Record online : 18 JAN 2013, DOI: 10.1016/j.febslet.2012.12.028

  15. Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons

    Journal of Comparative Neurology

    Volume 519, Issue 15, 15 October 2011, Pages: 3001–3018, Lindsay Hayes, Zhiwei Zhang, Paul Albert, Mark Zervas and Sohyun Ahn

    Version of Record online : 10 AUG 2011, DOI: 10.1002/cne.22711

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    Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

    International Journal of Cancer

    Volume 124, Issue 1, 1 January 2009, Pages: 109–119, Joon Won Yoon, Richard Gilbertson, Stephen Iannaccone, Philip Iannaccone and David Walterhouse

    Version of Record online : 15 OCT 2008, DOI: 10.1002/ijc.23929

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    Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-gli1 in autoimmune encephalomyelitis and multiple sclerosis

    Annals of Neurology

    Volume 64, Issue 4, October 2008, Pages: 417–427, Yue Wang, Jaime Imitola, Stine Rasmussen, Kevin C. O'Connor and Samia J. Khoury

    Version of Record online : 7 NOV 2008, DOI: 10.1002/ana.21457

  18. β1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1

    Journal of Cellular Physiology

    Volume 224, Issue 1, July 2010, Pages: 210–217, Hira Lal Goel, Jean M. Underwood, Jeffrey A. Nickerson, Chung-Cheng Hsieh and Lucia R. Languino

    Version of Record online : 23 MAR 2010, DOI: 10.1002/jcp.22116

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    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo

    CNS Neuroscience & Therapeutics

    Volume 19, Issue 12, December 2013, Pages: 926–936, Wen-Zhong Du, Yan Feng, Xiao-Feng Wang, Xing-Yin Piao, Yu-Qiong Cui, Ling-Chao Chen, Xu-Hui Lei, Xu Sun, Xing Liu, Han-Bing Wang, Xian-Feng Li, Dong-Bo Yang, Ying Sun, Zhe-Feng Zhao, Tao Jiang, Yong-Li Li and Chuan-Lu Jiang

    Version of Record online : 25 OCT 2013, DOI: 10.1111/cns.12163

  20. Gli1 is not required for Pdgfrα expression during mouse embryonic development


    Volume 73, Issue 2-3, March 2005, Pages: 109–119, Xiao-Qun Zhang, Gijs B Afink, Xin-Rong Hu, Karin Forsberg-Nilsson and Monica Nistér

    Version of Record online : 1 APR 2005, DOI: 10.1111/j.1432-0436.2005.07302003.x