Search Results

There are 17510 results for: content related to: Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice

  1. You have full text access to this OnlineOpen article
    FADD is a key regulator of lipid metabolism

    EMBO Molecular Medicine

    Hongqin Zhuang, Xueshi Wang, Daolong Zha, Ziyi Gan, Fangfang Cai, Pan Du, Yunwen Yang, Bingya Yang, Xiangyu Zhang, Chun Yao, Yuqiang Zhou, Chizhou Jiang, Shengwen Guan, Xuerui Zhang, Jing Zhang, Wenhui Jiang, Qingang Hu and Zi-Chun Hua

    Version of Record online : 29 JUN 2016, DOI: 10.15252/emmm.201505924

  2. You have full text access to this OnlineOpen article
    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Version of Record online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

  3. NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells

    The EMBO Journal

    Zhenhui Huang, Yarong Gao, Yuhui Sun, Chao Zhang, Yue Yin, Yasushi Shimoda, Kazutada Watanabe and Yaobo Liu

    Version of Record online : 18 MAY 2016, DOI: 10.15252/embj.201593460

  4. You have full text access to this OnlineOpen article
    IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

    EMBO Molecular Medicine

    Volume 3, Issue 6, June 2011, Pages: 348–361, Ourania Koltsida, Michael Hausding, Athanasios Stavropoulos, Sonja Koch, George Tzelepis, Caroline Übel, Sergei V. Kotenko, Paschalis Sideras, Hans A. Lehr, Marcus Tepe, Kevin M. Klucher, Sean E. Doyle, Markus F. Neurath, Susetta Finotto and Evangelos Andreakos

    Version of Record online : 3 MAY 2011, DOI: 10.1002/emmm.201100142

  5. You have full text access to this OnlineOpen article
    A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 526–546, Lavinia Palamiuc, Anna Schlagowski, Shyuan T Ngo, Aurelia Vernay, Sylvie Dirrig-Grosch, Alexandre Henriques, Anne-Laurence Boutillier, Joffrey Zoll, Andoni Echaniz-Laguna, Jean-Philippe Loeffler and Frédérique René

    Version of Record online : 27 MAR 2015, DOI: 10.15252/emmm.201404433

  6. You have full text access to this OnlineOpen article
    Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response

    EMBO Molecular Medicine

    Volume 7, Issue 1, January 2015, Pages: 24–41, Zhisheng Her, Terk-Shin Teng, Jeslin JL Tan, Teck-Hui Teo, Yiu-Wing Kam, Fok-Moon Lum, Wendy WL Lee, Christelle Gabriel, Rossella Melchiotti, Anand K Andiappan, Valeria Lulla, Aleksei Lulla, Mar K Win, Angela Chow, Subhra K Biswas, Yee-Sin Leo, Marc Lecuit, Andres Merits, Laurent Rénia and Lisa FP Ng

    Version of Record online : 1 DEC 2014, DOI: 10.15252/emmm.201404459

  7. Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

    The EMBO Journal

    Volume 35, Issue 9, 2 May 2016, Pages: 924–941, Christian Lange, Miguel Turrero Garcia, Ilaria Decimo, Francesco Bifari, Guy Eelen, Annelies Quaegebeur, Ruben Boon, Hui Zhao, Bram Boeckx, Junlei Chang, Christine Wu, Ferdinand Le Noble, Diether Lambrechts, Mieke Dewerchin, Calvin J Kuo, Wieland B Huttner and Peter Carmeliet

    Version of Record online : 8 FEB 2016, DOI: 10.15252/embj.201592372

  8. You have full text access to this OnlineOpen article
    The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

    The EMBO Journal

    Christopher P Webster, Emma F Smith, Claudia S Bauer, Annekathrin Moller, Guillaume M Hautbergue, Laura Ferraiuolo, Monika A Myszczynska, Adrian Higginbottom, Matthew J Walsh, Alexander J Whitworth, Brian K Kaspar, Kathrin Meyer, Pamela J Shaw, Andrew J Grierson and Kurt J De Vos

    Version of Record online : 22 JUN 2016, DOI: 10.15252/embj.201694401

  9. You have full text access to this OnlineOpen article
    Src is activated by the nuclear receptor peroxisome proliferator-activated receptor β/δ in ultraviolet radiation-induced skin cancer

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 80–98, Alexandra Montagner, Maria B Delgado, Corinne Tallichet-Blanc, Jeremy S K Chan, Ming K Sng, Hélène Mottaz, Gwendoline Degueurce, Yannick Lippi, Catherine Moret, Michael Baruchet, Maria Antsiferova, Sabine Werner, Daniel Hohl, Talal Al Saati, Pierre J Farmer, Nguan S Tan, Liliane Michalik and Walter Wahli

    Version of Record online : 6 NOV 2013, DOI: 10.1002/emmm.201302666

  10. You have full text access to this OnlineOpen article
    Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 92–104, Yisheng Yang, Benny Hung-Junn Chang and Lawrence Chan

    Version of Record online : 29 NOV 2012, DOI: 10.1002/emmm.201201398

  11. You have full text access to this OnlineOpen article
    Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK

    The EMBO Journal

    Volume 34, Issue 3, 03 February 2015, Pages: 275–293, Siyuan Dai, Zijian Tang, Junyue Cao, Wei Zhou, Huawen Li, Stephen Sampson and Chengkai Dai

    Version of Record online : 25 NOV 2014, DOI: 10.15252/embj.201489062

  12. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs

    EMBO reports

    Hiroaki Kajiho, Yuko Kajiho, Emanuela Frittoli, Stefano Confalonieri, Giovanni Bertalot, Giuseppe Viale, Pier Paolo Di Fiore, Amanda Oldani, Massimiliano Garre, Galina V Beznoussenko, Andrea Palamidessi, Manuela Vecchi, Philippe Chavrier, Frank Perez and Giorgio Scita

    Version of Record online : 2 JUN 2016, DOI: 10.15252/embr.201642032

  13. You have free access to this content
    BIG3 inhibits insulin granule biogenesis and insulin secretion

    EMBO reports

    Volume 15, Issue 6, June 2014, Pages: 714–722, Hongyu Li, Shunhui Wei, Kenneth Cheng, Natalia V Gounko, Russell E Ericksen, Aimin Xu, Wanjin Hong and Weiping Han

    Version of Record online : 7 APR 2014, DOI: 10.1002/embr.201338181

  14. You have full text access to this OnlineOpen article
    Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus

    EMBO Molecular Medicine

    Volume 4, Issue 12, December 2012, Pages: 1244–1260, Nathan W. Bartlett, Louise Slater, Nicholas Glanville, Jennifer J. Haas, Gaetano Caramori, Paolo Casolari, Deborah L. Clarke, Simon D. Message, Julia Aniscenko, Tatiana Kebadze, Jie Zhu, Patrick Mallia, Joseph P. Mizgerd, Maria Belvisi, Alberto Papi, Sergei V. Kotenko, Sebastian L. Johnston and Michael R. Edwards

    Version of Record online : 14 NOV 2012, DOI: 10.1002/emmm.201201650

  15. You have full text access to this OnlineOpen article
    SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development

    The EMBO Journal

    Madalina Raducu, Ella Fung, Sébastien Serres, Paola Infante, Alessandro Barberis, Roman Fischer, Claire Bristow, Marie-Laëtitia Thézénas, Csaba Finta, John C Christianson, Francesca M Buffa, Benedikt M Kessler, Nicola R Sibson, Lucia Di Marcotullio, Rune Toftgård and Vincenzo D'Angiolella

    Version of Record online : 27 MAY 2016, DOI: 10.15252/embj.201593374

  16. SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

    EMBO reports

    Volume 17, Issue 6, June 2016, Pages: 811–822, Lisha Zhou, Fang Wang, Renqiang Sun, Xiufei Chen, Mengli Zhang, Qi Xu, Yi Wang, Shiwen Wang, Yue Xiong, Kun-Liang Guan, Pengyuan Yang, Hongxiu Yu and Dan Ye

    Version of Record online : 9 APR 2016, DOI: 10.15252/embr.201541643

  17. You have full text access to this OnlineOpen article
    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 519–538, Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg and Massimo Loda

    Version of Record online : 4 FEB 2014, DOI: 10.1002/emmm.201302734

    Corrected by:

    Corrigendum: A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    Vol. 6, Issue 10, 1357, Version of Record online: 1 SEP 2014

  18. You have full text access to this OnlineOpen article
    Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 259–277, Youssef Hibaoui, Iwona Grad, Audrey Letourneau, M Reza Sailani, Sophie Dahoun, Federico A Santoni, Stefania Gimelli, Michel Guipponi, Marie Françoise Pelte, Frédérique Béna, Stylianos E Antonarakis and Anis Feki

    Version of Record online : 27 DEC 2013, DOI: 10.1002/emmm.201302848

  19. You have full text access to this OnlineOpen article
    Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer

    EMBO Molecular Medicine

    Volume 8, Issue 4, April 2016, Pages: 388–406, Yukie Takabatake, Claus Oxvig, Chandandeep Nagi, Kerin Adelson, Shabnam Jaffer, Hank Schmidt, Patricia J Keely, Kevin W Eliceiri, John Mandeli and Doris Germain

    Version of Record online : 8 MAR 2016, DOI: 10.15252/emmm.201606273

  20. You have full text access to this OnlineOpen article
    Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

    EMBO Molecular Medicine

    Volume 4, Issue 12, December 2012, Pages: 1276–1293, Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chun Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen and Yu-Sun Chang

    Version of Record online : 15 OCT 2012, DOI: 10.1002/emmm.201201569