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There are 8670 results for: content related to: Deleterious effects of neuronal accumulation of glycogen in flies and mice

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    HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice

    EMBO Molecular Medicine

    Volume 7, Issue 1, January 2015, Pages: 78–101, Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa, Xigui Chen, Hidenori Homma, Toshikazu Sasabe, Jun Shimizu, Shigeomi Shimizu, Takuya Tamura, Shin-ichi Muramatsu and Hitoshi Okazawa

    Version of Record online : 15 DEC 2014, DOI: 10.15252/emmm.201404392

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    WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer

    EMBO Molecular Medicine

    Volume 5, Issue 2, February 2013, Pages: 264–279, Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria Yesayan, Meghan Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya Ulasov, Maciej S. Lesniak, Rebecca Wolsky, Laurent A. Bentolila, Stephen G. Grant, David Elashoff, Stephan Lehr, Jean J. Latimer, Shikha Bose, Husain Sattar, Susan A. Krum and Gustavo A. Miranda-Carboni

    Version of Record online : 11 JAN 2013, DOI: 10.1002/emmm.201201320

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    Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 608–625, Nathalie Pierrot, Donatienne Tyteca, Ludovic D'auria, Ilse Dewachter, Philippe Gailly, Aurélie Hendrickx, Bernadette Tasiaux, Laetitia El Haylani, Nathalie Muls, Francisca N'Kuli, Annie Laquerrière, Jean-Baptiste Demoulin, Dominique Campion, Jean-Pierre Brion, Pierre J. Courtoy, Pascal Kienlen-Campard and Jean-Noël Octave

    Version of Record online : 2 APR 2013, DOI: 10.1002/emmm.201202215

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    Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease

    EMBO Molecular Medicine

    Felix Nitschke, Mitchell A Sullivan, Peixiang Wang, Xiaochu Zhao, Erin E Chown, Ami M Perri, Lori Israelian, Lucia Juana-López, Paola Bovolenta, Santiago Rodríguez de Córdoba, Martin Steup and Berge A Minassian

    Version of Record online : 23 MAY 2017, DOI: 10.15252/emmm.201707608

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    The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

    EMBO Molecular Medicine

    Volume 7, Issue 11, November 2015, Pages: 1426–1449, Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis and Cheng Wang

    Version of Record online : 28 SEP 2015, DOI: 10.15252/emmm.201404976

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    Modulation of mTOR signaling as a strategy for the treatment of Pompe disease

    EMBO Molecular Medicine

    Volume 9, Issue 3, March 2017, Pages: 353–370, Jeong-A Lim, Lishu Li, Orian S Shirihai, Kyle M Trudeau, Rosa Puertollano and Nina Raben

    Version of Record online : 27 JAN 2017, DOI: 10.15252/emmm.201606547

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    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 519–538, Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg and Massimo Loda

    Version of Record online : 4 FEB 2014, DOI: 10.1002/emmm.201302734

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    Corrigendum: A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    Vol. 6, Issue 10, 1357, Version of Record online: 1 SEP 2014

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    Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

    EMBO Molecular Medicine

    Volume 5, Issue 8, August 2013, Pages: 1165–1179, Yi-Cheng Chang, Yu-Hsiang Yu, Jin-Yuh Shew, Wei-Jei Lee, Juey-Jen Hwang, Yen-Hui Chen, Yet-Ran Chen, Pei-Chi Wei, Lee-Ming Chuang and Wen-Hwa Lee

    Version of Record online : 4 JUL 2013, DOI: 10.1002/emmm.201302679

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    Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 660–673, Francesc X. Guix, Tina Wahle, Kristel Vennekens, An Snellinx, Lucía Chávez-Gutiérrez, Gerard Ill-Raga, Eva Ramos-Fernandez, Cristina Guardia-Laguarta, Alberto Lleó, Muriel Arimon, Oksana Berezovska, Francisco J. Muñoz, Carlos G. Dotti and Bart De Strooper

    Version of Record online : 2 MAY 2012, DOI: 10.1002/emmm.201200243

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    The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 670–687, Marta Luna-Sánchez, Elena Díaz-Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla-García, Enrique Javier Cobos, Germaine Escames, Dario Acuña-Castroviejo, Catarina M Quinzii and Luis Carlos López

    Version of Record online : 23 MAR 2015, DOI: 10.15252/emmm.201404632

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    A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1322–1334, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez-Zapico and Min Li

    Version of Record online : 16 JUL 2013, DOI: 10.1002/emmm.201302507

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    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Version of Record online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

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    DOK7 gene therapy enhances motor activity and life span in ALS model mice

    EMBO Molecular Medicine

    Sadanori Miyoshi, Tohru Tezuka, Sumimasa Arimura, Taro Tomono, Takashi Okada and Yuji Yamanashi

    Version of Record online : 10 MAY 2017, DOI: 10.15252/emmm.201607298

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    SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias

    EMBO Molecular Medicine

    Volume 9, Issue 4, April 2017, Pages: 415–429, Shiraz Haron-Khun, David Weisbrod, Hanna Bueno, Dor Yadin, Joachim Behar, Asher Peretz, Ofer Binah, Edith Hochhauser, Michael Eldar, Yael Yaniv, Michael Arad and Bernard Attali

    Version of Record online : 20 FEB 2017, DOI: 10.15252/emmm.201606937

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    Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 394–410, Harsha D Devalla, Verena Schwach, John W Ford, James T Milnes, Said El-Haou, Claire Jackson, Konstantinos Gkatzis, David A Elliott, Susana M Chuva de Sousa Lopes, Christine L Mummery, Arie O Verkerk and Robert Passier

    Version of Record online : 19 FEB 2015, DOI: 10.15252/emmm.201404757

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    Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer

    EMBO Molecular Medicine

    Volume 3, Issue 8, August 2011, Pages: 451–464, Wendy WeiJia Soon, Lance David Miller, Michael A. Black, Cyril Dalmasso, Xiu Bin Chan, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Kartiki V. Desai and Edison T. Liu

    Version of Record online : 8 JUN 2011, DOI: 10.1002/emmm.201100150

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    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Version of Record online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

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    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Version of Record online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

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    Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1072–1086, Larissa Cardilo-Reis, Sabrina Gruber, Sabine M. Schreier, Maik Drechsler, Nikolina Papac-Milicevic, Christian Weber, Oswald Wagner, Herbert Stangl, Oliver Soehnlein and Christoph J. Binder

    Version of Record online : 2 OCT 2012, DOI: 10.1002/emmm.201201374

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    N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

    EMBO Molecular Medicine

    Volume 4, Issue 2, February 2012, Pages: 93–108, Wen Liu, Fei Xing, Megumi Iiizumi-Gairani, Hiroshi Okuda, Misako Watabe, Sudha K. Pai, Puspa R. Pandey, Shigeru Hirota, Aya Kobayashi, Yin-Yuan Mo, Koji Fukuda, Yi Li and Kounosuke Watabe

    Version of Record online : 13 JAN 2012, DOI: 10.1002/emmm.201100190