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There are 24713 results for: content related to: The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice

  1. You have full text access to this OnlineOpen article
    Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer

    EMBO Molecular Medicine

    Volume 3, Issue 8, August 2011, Pages: 451–464, Wendy WeiJia Soon, Lance David Miller, Michael A. Black, Cyril Dalmasso, Xiu Bin Chan, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Kartiki V. Desai and Edison T. Liu

    Article first published online : 8 JUN 2011, DOI: 10.1002/emmm.201100150

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    The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

    EMBO Molecular Medicine

    Marta Luna-Sánchez, Elena Díaz-Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla-García, Enrique Javier Cobos, Germaine Escames, Dario Acuña-Castroviejo, Catarina M Quinzii and Luis Carlos López

    Article first published online : 23 MAR 2015, DOI: 10.15252/emmm.201404632

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    A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1322–1334, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez-Zapico and Min Li

    Article first published online : 16 JUL 2013, DOI: 10.1002/emmm.201302507

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    Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 4, April 2012, Pages: 344–352, Nobuto Kakuda, Mikio Shoji, Hiroyuki Arai, Katsutoshi Furukawa, Takeshi Ikeuchi, Kohei Akazawa, Mako Takami, Hiroyuki Hatsuta, Shigeo Murayama, Yasuhiro Hashimoto, Masakazu Miyajima, Hajime Arai, Yu Nagashima, Haruyasu Yamaguchi, Ryozo Kuwano, Kazuhiro Nagaike, Yasuo Ihara and the Japanese Alzheimer's Disease Neuroimaging Initiative

    Article first published online : 21 FEB 2012, DOI: 10.1002/emmm.201200214

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    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Article first published online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

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    Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 394–410, Harsha D Devalla, Verena Schwach, John W Ford, James T Milnes, Said El-Haou, Claire Jackson, Konstantinos Gkatzis, David A Elliott, Susana M Chuva de Sousa Lopes, Christine L Mummery, Arie O Verkerk and Robert Passier

    Article first published online : 19 FEB 2015, DOI: 10.15252/emmm.201404757

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    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Article first published online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

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    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Article first published online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

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    Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1072–1086, Larissa Cardilo-Reis, Sabrina Gruber, Sabine M. Schreier, Maik Drechsler, Nikolina Papac-Milicevic, Christian Weber, Oswald Wagner, Herbert Stangl, Oliver Soehnlein and Christoph J. Binder

    Article first published online : 2 OCT 2012, DOI: 10.1002/emmm.201201374

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    A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 438–449, Chuan Liu, Hongyu Ding, Xiaoxi Li, Christian P Pallasch, Liya Hong, Dianwu Guo, Yi Chen, Difei Wang, Wei Wang, Yajie Wang, Michael T Hemann and Hai Jiang

    Article first published online : 10 MAR 2015, DOI: 10.15252/emmm.201404580

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    Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

    EMBO Molecular Medicine

    Kevin White, Yu Lu, Sofia Annis, Andrew E Hale, B Nelson Chau, James E Dahlman, Craig Hemann, Alexander R Opotowsky, Sara O Vargas, Ivan Rosas, Mark A Perrella, Juan C Osorio, Kathleen J Haley, Brian B Graham, Rahul Kumar, Rajan Saggar, Rajeev Saggar, W Dean Wallace, David J Ross, Omar F Khan, Andrew Bader, Bernadette R Gochuico, Majed Matar, Kevin Polach, Nicolai M Johannessen, Haydn M Prosser, Daniel G Anderson, Robert Langer, Jay L Zweier, Laurence A Bindoff, David Systrom, Aaron B Waxman, Richard C Jin and Stephen Y Chan

    Article first published online : 30 MAR 2015, DOI: 10.15252/emmm.201404511

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    Towards a new combination therapy for tuberculosis with next generation benzothiazinones

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 372–383, Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van der Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson and Stewart T Cole

    Article first published online : 5 FEB 2014, DOI: 10.1002/emmm.201303575

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    Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53

    EMBO Molecular Medicine

    Volume 4, Issue 6, June 2012, Pages: 515–527, Chris T. Williamson, Eiji Kubota, Jeffrey D. Hamill, Alexander Klimowicz, Ruiqiong Ye, Huong Muzik, Michelle Dean, LiRen Tu, David Gilley, Anthony M. Magliocco, Bruce C. McKay, D. Gwyn Bebb and Susan P. Lees-Miller

    Article first published online : 13 MAR 2012, DOI: 10.1002/emmm.201200229

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    Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 149–166, Yan Liu, Oriana E. Hawkins, Yingjun Su, Anna E. Vilgelm, Tammy Sobolik, Yee-Mon Thu, Sara Kantrow, Ryan C. Splittgerber, Sarah Short, Katayoun I. Amiri, Jeffery A. Ecsedy, Jeffery A. Sosman, Mark C. Kelley and Ann Richmond

    Article first published online : 25 NOV 2012, DOI: 10.1002/emmm.201201378

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    Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine

    EMBO Molecular Medicine

    Joan Castellsagué, Bernat Gel, Juana Fernández-Rodríguez, Roger Llatjós, Ignacio Blanco, Yolanda Benavente, Diana Pérez-Sidelnikova, Javier García-del Muro, Joan Maria Viñals, August Vidal, Rafael Valdés-Mas, Ernest Terribas, Adriana López-Doriga, Miguel Angel Pujana, Gabriel Capellá, Xose S Puente, Eduard Serra, Alberto Villanueva and Conxi Lázaro

    Article first published online : 25 MAR 2015, DOI: 10.15252/emmm.201404430

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    Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 122–136, Verena Labi, Daniela Bertele, Claudia Woess, Denise Tischner, Florian J. Bock, Sven Schwemmers, Heike L. Pahl, Stephan Geley, Mirjam Kunze, Charlotte M. Niemeyer, Andreas Villunger and Miriam Erlacher

    Article first published online : 24 NOV 2012, DOI: 10.1002/emmm.201201235

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    A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis

    EMBO Molecular Medicine

    Volume 2, Issue 5, May 2010, Pages: 172–187, Eric Boilard, Ying Lai, Katherine Larabee, Barbara Balestrieri, Farideh Ghomashchi, Daisuke Fujioka, Reuben Gobezie, Jonathan S. Coblyn, Michael E. Weinblatt, Elena M. Massarotti, Thomas S. Thornhill, Maziar Divangahi, Heinz Remold, Gérard Lambeau, Michael H. Gelb, Jonathan P. Arm and David M. Lee

    Article first published online : 29 APR 2010, DOI: 10.1002/emmm.201000072

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    Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

    EMBO Molecular Medicine

    Volume 4, Issue 1, January 2012, Pages: 52–67, Yun-Yong Park, Kyounghyun Kim, Sang-Bae Kim, Bryan T. Hennessy, Soo Mi Kim, Eun Sung Park, Jae Yun Lim, Jane Li, Yiling Lu, Ana Maria Gonzalez-Angulo, Woojin Jeong, Gordon B. Mills, Stephen Safe and Ju-Seog Lee

    Article first published online : 15 DEC 2011, DOI: 10.1002/emmm.201100187

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    miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity

    EMBO Molecular Medicine

    Volume 4, Issue 9, September 2012, Pages: 882–895, Ryan M. Allen, Tyler J. Marquart, Carolyn J. Albert, Frederick J. Suchy, David Q.-H. Wang, Meenakshisundaram Ananthanarayanan, David A. Ford and Ángel Baldán

    Article first published online : 5 JUL 2012, DOI: 10.1002/emmm.201201228

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    ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 278–294, Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M. McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch and Gail E Sonenshein

    Article first published online : 27 DEC 2013, DOI: 10.1002/emmm.201303373