Search Results

There are 7866 results for: content related to: Fc-fusion proteins: new developments and future perspectives

  1. Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 6, June 2015, Pages: 1866–1884, Liming Liu

    Version of Record online : 14 APR 2015, DOI: 10.1002/jps.24444

  2. Pharmacokinetics of Peptide–Fc Fusion Proteins

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 1, January 2014, Pages: 53–64, Benjamin Wu and Yu-Nien Sun

    Version of Record online : 27 NOV 2013, DOI: 10.1002/jps.23783

  3. Monomeric Fc Fusion Technology: An Approach to Create Long-Lasting Clotting Factors

    Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives

    Jennifer A. Dumont, Xiaomei Jin, Robert T. Peters, Alvin Luk, Glenn F. Pierce, Alan J. Bitonti, Pages: 189–206, 2012

    Published Online : 6 FEB 2012, DOI: 10.1002/9783527644827.ch10

  4. Half-Life Extension by Fusion to the Fc Region

    Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives

    Jalal A. Jazayeri, Graeme J. Carroll, Pages: 157–188, 2012

    Published Online : 6 FEB 2012, DOI: 10.1002/9783527644827.ch9

  5. Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model

    Journal of Thrombosis and Haemostasis

    Volume 15, Issue 4, April 2017, Pages: 721–734, D. Levin, H. A. D. Lagassé, E. Burch, S. Strome, S. Tan, H. Jiang, Z. E. Sauna and B. Golding

    Version of Record online : 2 MAR 2017, DOI: 10.1111/jth.13649

  6. Resolution of disulfide heterogeneity in Nogo receptor 1 fusion proteins by molecular engineering

    Biotechnology and Applied Biochemistry

    Volume 57, Issue 1, September 2010, Pages: 31–45, Paul H. Weinreb, Dingyi Wen, Fang Qian, Craig P. Wildes, Ellen A. Garber, Lee Walus, Mi-young Jung, Joy Wang, Jane K. Relton, Joseph Amatucci, Ruizhong Wang, Frank Porreca, Laura Silvian, Werner Meier, R. Blake Pepinsky and Daniel H. S. Lee

    Version of Record online : 23 DEC 2010, DOI: 10.1042/BA20100061

  7. Placental Transfer of Fc-Containing Biopharmaceuticals across Species, an Industry Survey Analysis

    Birth Defects Research Part B: Developmental and Reproductive Toxicology

    Volume 98, Issue 6, December 2013, Pages: 459–485, Christopher J. Bowman, William J. Breslin, Anu V. Connor, Pauline L. Martin, Graeme J. Moffat, Lakshmi Sivaraman, M. Belen Tornesi and Simon Chivers

    Version of Record online : 3 JAN 2014, DOI: 10.1002/bdrb.21089

  8. You have full text access to this Open Access content
    Engineered therapeutic antibodies with improved effector functions

    Cancer Science

    Volume 100, Issue 9, September 2009, Pages: 1566–1572, Tsuguo Kubota, Rinpei Niwa, Mitsuo Satoh, Shiro Akinaga, Kenya Shitara and Nobuo Hanai

    Version of Record online : 18 MAY 2009, DOI: 10.1111/j.1349-7006.2009.01222.x

  9. Application of a kosmotrope-based solubility assay to multiple protein therapeutic classes indicates broad use as a high-throughput screen for protein therapeutic aggregation propensity

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 8, August 2013, Pages: 2424–2439, Aaron P. Yamniuk, Noah Ditto, Mehul Patel, Jun Dai, Preeti Sejwal, Paul Stetsko and Michael L. Doyle

    Version of Record online : 27 MAY 2013, DOI: 10.1002/jps.23618

  10. Testing for the erythropoiesis-stimulating agent Sotatercept/ACE-011 (ActRIIA-Fc) in serum by means of Western blotting and LC-HRMS

    Drug Testing and Analysis

    Volume 8, Issue 11-12, November-December 2016, Pages: 1152–1161, Katja Walpurgis, Andreas Thomas, Matthias Vogel, Christian Reichel, Hans Geyer, Wilhelm Schänzer and Mario Thevis

    Version of Record online : 13 OCT 2016, DOI: 10.1002/dta.2093

  11. Co-opting biology to deliver drugs

    Biotechnology and Bioengineering

    Volume 111, Issue 9, September 2014, Pages: 1699–1716, Parisa Yousefpour and Ashutosh Chilkoti

    Version of Record online : 21 JUL 2014, DOI: 10.1002/bit.25307

  12. Detection and localization of Cripto-1 binding in mouse mammary epithelial cells and in the mouse mammary gland using an immunoglobulin–cripto-1 fusion protein

    Journal of Cellular Physiology

    Volume 190, Issue 1, January 2002, Pages: 74–82, Caterina Bianco, Nicola Normanno, Antonella De Luca, Monica Rosaria Maiello, Christian Wechselberger, Youping Sun, Nadia Khan, Heather Adkins, Michele Sanicola, Barbara Vonderhaar, Bruce Cohen, Masaharu Seno and David Salomon

    Version of Record online : 2 NOV 2001, DOI: 10.1002/jcp.10037

  13. You have full text access to this OnlineOpen article
    The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein

    Journal of Thrombosis and Haemostasis

    Volume 15, Issue 6, June 2017, Pages: 1167–1179, N. C. Leksa, P.-L. Chiu, G. M. Bou-Assaf, C. Quan, Z. Liu, A. B. Goodman, M. G. Chambers, S. E. Tsutakawa, M. Hammel, R. T. Peters, T. Walz and J. D. Kulman

    Version of Record online : 3 MAY 2017, DOI: 10.1111/jth.13700

  14. You have free access to this content
    T-shaped arrangement of the recombinant agrin G3 – IgG Fc protein

    Protein Science

    Volume 20, Issue 6, June 2011, Pages: 931–940, Trushar R. Patel, Markus Meier, Jianhua Li, Gordon Morris, Arthur J. Rowe and Jörg Stetefeld

    Version of Record online : 26 APR 2011, DOI: 10.1002/pro.628

  15. You have free access to this content
    Longer-acting clotting factor concentrates for hemophilia

    Journal of Thrombosis and Haemostasis

    Volume 13, Issue S1, June 2015, Pages: S167–S175, J. S. Powell

    Version of Record online : 19 JUN 2015, DOI: 10.1111/jth.12912

  16. You have full text access to this OnlineOpen article
    Biochemical and functional characterization of a recombinant monomeric factor VIII–Fc fusion protein

    Journal of Thrombosis and Haemostasis

    Volume 11, Issue 1, January 2013, Pages: 132–141, R. T. PETERS, G. TOBY, Q. LU, T. LIU, J. D. KULMAN, S. C. LOW, A. J. BITONTI and G. F. PIERCE

    Version of Record online : 27 JAN 2013, DOI: 10.1111/jth.12076

  17. Enhancing the Production of Fc Fusion Protein in Fed-Batch Fermentation of Pichia pastoris by Design of Experiments

    Biotechnology Progress

    Volume 23, Issue 3, 2007, Pages: 621–625, Henry Lin, Tina Kim, Fei Xiong and Xiaoming Yang

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp0603199

  18. Expression and characterization of human growth hormone–Fc fusion proteins for transcytosis induction

    Biotechnology and Applied Biochemistry

    Volume 46, Issue 4, April 2007, Pages: 211–217, Chang Hoon Lee, Jung Hee Woo, Kwang Keun Cho, Seung Ha Kang, Sang Kee Kang and Yun Jaie Choi

    Version of Record online : 23 DEC 2010, DOI: 10.1042/BA20060083

  19. ANTIBODIES AND DERIVATIVES

    Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs

    Rodney J. Y. Ho, Milo Gibaldi, Pages: 139–210, 2013

    Published Online : 25 OCT 2013, DOI: 10.1002/9781118660485.ch9

  20. You have free access to this content
    Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein

    Diabetes/Metabolism Research and Reviews

    Volume 26, Issue 4, May 2010, Pages: 287–296, Wolfgang Glaesner, Andrew Mark Vick, Rohn Millican, Bernice Ellis, Sheng-Hung Tschang, Yu Tian, Krister Bokvist, Martin Brenner, Anja Koester, Niels Porksen, Garret Etgen and Tom Bumol

    Version of Record online : 30 APR 2010, DOI: 10.1002/dmrr.1080