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There are 7721 results for: content related to: Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults

  1. You have full text access to this OnlineOpen article
    p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

    EMBO Molecular Medicine

    Volume 2, Issue 11, November 2010, Pages: 472–486, Alicia M. Cole, Rachel A. Ridgway, Sahra E. Derkits, Lee Parry, Nick Barker, Hans Clevers, Alan R. Clarke and Owen J. Sansom

    Version of Record online : 26 OCT 2010, DOI: 10.1002/emmm.201000101

  2. You have full text access to this OnlineOpen article
    Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia

    EMBO Molecular Medicine

    Volume 2, Issue 3, March 2010, Pages: 98–110, Andrea Hoelbl, Christian Schuster, Boris Kovacic, Bingmei Zhu, Mark Wickre, Maria A. Hoelzl, Sabine Fajmann, Florian Grebien, Wolfgang Warsch, Gabriele Stengl, Lothar Hennighausen, Valeria Poli, Hartmut Beug, Richard Moriggl and Veronika Sexl

    Version of Record online : 3 MAR 2010, DOI: 10.1002/emmm.201000062

  3. You have full text access to this OnlineOpen article
    HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

    EMBO Molecular Medicine

    Volume 9, Issue 2, February 2017, Pages: 181–197, Kevin B Myant, Patrizia Cammareri, Michael C Hodder, Jimi Wills, Alex Von Kriegsheim, Balázs Győrffy, Mamun Rashid, Simona Polo, Elena Maspero, Lynsey Vaughan, Basanta Gurung, Evan Barry, Angeliki Malliri, Fernando Camargo, David J Adams, Antonio Iavarone, Anna Lasorella and Owen J Sansom

    Version of Record online : 22 DEC 2016, DOI: 10.15252/emmm.201606684

  4. You have full text access to this OnlineOpen article
    A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases

    EMBO Molecular Medicine

    Volume 8, Issue 6, June 2016, Pages: 609–625, Jakob Körbelin, Godwin Dogbevia, Stefan Michelfelder, Dirk A Ridder, Agnes Hunger, Jan Wenzel, Henning Seismann, Melanie Lampe, Jacqueline Bannach, Manolis Pasparakis, Jürgen A Kleinschmidt, Markus Schwaninger and Martin Trepel

    Version of Record online : 22 APR 2016, DOI: 10.15252/emmm.201506078

  5. You have full text access to this OnlineOpen article
    SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis

    EMBO Molecular Medicine

    Volume 4, Issue 8, August 2012, Pages: 776–790, Meiling Gao, Rachana Patel, Imran Ahmad, Janis Fleming, Joanne Edwards, Stuart McCracken, Kanagasabai Sahadevan, Morag Seywright, Jim Norman, Owen Sansom and Hing Y. Leung

    Version of Record online : 31 MAY 2012, DOI: 10.1002/emmm.201100944

  6. You have full text access to this Open Access content
    Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 564–576, Ina Rohwedder, Eloi Montanez, Karsten Beckmann, Eva Bengtsson, Pontus Dunér, Jan Nilsson, Oliver Soehnlein and Reinhard Fässler

    Version of Record online : 19 APR 2012, DOI: 10.1002/emmm.201200237

  7. You have full text access to this OnlineOpen article
    Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice

    EMBO Molecular Medicine

    Volume 5, Issue 6, June 2013, Pages: 949–964, Joachim Albers, Michal Rajski, Désirée Schönenberger, Sabine Harlander, Peter Schraml, Adriana von Teichman, Strahil Georgiev, Peter J. Wild, Holger Moch, Wilhelm Krek and Ian J. Frew

    Version of Record online : 22 APR 2013, DOI: 10.1002/emmm.201202231

  8. You have full text access to this OnlineOpen article
    Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization

    EMBO Molecular Medicine

    Volume 8, Issue 6, June 2016, Pages: 670–678, Anika Lückoff, Albert Caramoy, Rebecca Scholz, Marco Prinz, Ulrich Kalinke and Thomas Langmann

    Version of Record online : 3 MAY 2016, DOI: 10.15252/emmm.201505994

  9. You have full text access to this OnlineOpen article
    Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1720–1739, Jeong-Hwan Yoon, Su Myung Jung, Seok Hee Park, Mitsuyasu Kato, Tadashi Yamashita, In-Kyu Lee, Katsuko Sudo, Susumu Nakae, Jin Soo Han, Ok-Hee Kim, Byung-Chul Oh, Takayuki Sumida, Masahiko Kuroda, Ji-Hyeon Ju, Kyeong Cheon Jung, Seong Hoe Park, Dae-Kee Kim and Mizuko Mamura

    Version of Record online : 11 OCT 2013, DOI: 10.1002/emmm.201302524

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    Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms

    EMBO Molecular Medicine

    Volume 8, Issue 3, March 2016, Pages: 208–231, Alexander G Marneros

    Version of Record online : 24 FEB 2016, DOI: 10.15252/emmm.201505613

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    KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

    EMBO Molecular Medicine

    Volume 8, Issue 1, January 2016, Pages: 6–24, Roberto Cuttano, Noemi Rudini, Luca Bravi, Monica Corada, Costanza Giampietro, Eleanna Papa, Marco Francesco Morini, Luigi Maddaluno, Nicolas Baeyens, Ralf H Adams, Mukesh K Jain, Gary K Owens, Martin Schwartz, Maria Grazia Lampugnani and Elisabetta Dejana

    Version of Record online : 26 NOV 2015, DOI: 10.15252/emmm.201505433

  12. You have full text access to this OnlineOpen article
    STIM1 and STIM2-mediated Ca2+ influx regulates antitumour immunity by CD8+ T cells

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1311–1321, Carl Weidinger, Patrick J. Shaw and Stefan Feske

    Version of Record online : 6 AUG 2013, DOI: 10.1002/emmm.201302989

  13. Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing

    The EMBO Journal

    Volume 35, Issue 23, 01 December 2016, Pages: 2536–2552, Christian Vogl, Iliana Panou, Gulnara Yamanbaeva, Carolin Wichmann, Sara J Mangosing, Fabio Vilardi, Artur A Indzhykulian, Tina Pangršič, Rosamaria Santarelli, Montserrat Rodriguez-Ballesteros, Thomas Weber, Sangyong Jung, Elena Cardenas, Xudong Wu, Sonja M Wojcik, Kelvin Y Kwan, Ignacio del Castillo, Blanche Schwappach, Nicola Strenzke, David P Corey, Shuh-Yow Lin and Tobias Moser

    Version of Record online : 25 JUL 2016, DOI: 10.15252/embj.201593565

  14. You have full text access to this OnlineOpen article
    Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 275–287, Christina Ising, Sybille Koehler, Sebastian Brähler, Carsten Merkwirth, Martin Höhne, Olivier R Baris, Henning Hagmann, Martin Kann, Francesca Fabretti, Claudia Dafinger, Wilhelm Bloch, Bernhard Schermer, Andreas Linkermann, Jens C Brüning, Christine E Kurschat, Roman-Ulrich Müller, Rudolf J Wiesner, Thomas Langer, Thomas Benzing and Paul Thomas Brinkkoetter

    Version of Record online : 2 FEB 2015, DOI: 10.15252/emmm.201404916

  15. You have full text access to this OnlineOpen article
    Epidermal p65/NF-κB signalling is essential for skin carcinogenesis

    EMBO Molecular Medicine

    Volume 6, Issue 7, July 2014, Pages: 970–983, Chun Kim and Manolis Pasparakis

    Version of Record online : 21 JUN 2014, DOI: 10.15252/emmm.201303541

  16. You have full text access to this OnlineOpen article
    Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease

    EMBO Molecular Medicine

    Volume 6, Issue 11, November 2014, Pages: 1423–1435, Daniel Bilbao, Luisa Luciani, Bjarki Johannesson, Agnieszka Piszczek and Nadia Rosenthal

    Version of Record online : 3 NOV 2014, DOI: 10.15252/emmm.201303376

  17. You have full text access to this OnlineOpen article
    Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

    EMBO Molecular Medicine

    Thomas Mathivet, Claire Bouleti, Matthias Van Woensel, Fabio Stanchi, Tina Verschuere, Li-Kun Phng, Joost Dejaegher, Marly Balcer, Ken Matsumoto, Petya B Georgieva, Jochen Belmans, Raf Sciot, Christian Stockmann, Massimiliano Mazzone, Steven De Vleeschouwer and Holger Gerhardt

    Version of Record online : 16 OCT 2017, DOI: 10.15252/emmm.201607445

  18. You have full text access to this OnlineOpen article
    Vezatin, an integral membrane protein of adherens junctions, is required for the sound resilience of cochlear hair cells

    EMBO Molecular Medicine

    Volume 1, Issue 2, May 2009, Pages: 125–138, Amel Bahloul, Marie-Christine Simmler, Vincent Michel, Michel Leibovici, Isabelle Perfettini, Isabelle Roux, Dominique Weil, Sylvie Nouaille, Jian Zuo, Cristina Zadro, Danilo Licastro, Paolo Gasparini, Paul Avan, Jean-Pierre Hardelin and Christine Petit

    Version of Record online : 8 MAY 2009, DOI: 10.1002/emmm.200900015

  19. You have full text access to this OnlineOpen article
    Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice

    EMBO Molecular Medicine

    Volume 9, Issue 7, July 2017, Pages: 890–905, Anja Feldner, M Gordian Adam, Fabian Tetzlaff, Iris Moll, Dorde Komljenovic, Felix Sahm, Tobias Bäuerle, Hiroshi Ishikawa, Horst Schroten, Thomas Korff, Ilse Hofmann, Hartwig Wolburg, Andreas von Deimling and Andreas Fischer

    Version of Record online : 12 MAY 2017, DOI: 10.15252/emmm.201606430

  20. You have full text access to this OnlineOpen article
    Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

    EMBO Molecular Medicine

    Volume 4, Issue 3, March 2012, Pages: 218–233, Markus Eberl, Stefan Klingler, Doris Mangelberger, Andrea Loipetzberger, Helene Damhofer, Kerstin Zoidl, Harald Schnidar, Hendrik Hache, Hans-Christian Bauer, Flavio Solca, Cornelia Hauser-Kronberger, Alexandre N. Ermilov, Monique E. Verhaegen, Christopher K. Bichakjian, Andrzej A. Dlugosz, Wilfried Nietfeld, Maria Sibilia, Hans Lehrach, Christoph Wierling and Fritz Aberger

    Version of Record online : 1 FEB 2012, DOI: 10.1002/emmm.201100201