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There are 15109 results for: content related to: Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults

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    Krüppel-Like Zinc Finger Protein Glis3 Promotes Osteoblast Differentiation by Regulating FGF18 Expression

    Journal of Bone and Mineral Research

    Volume 22, Issue 8, August 2007, Pages: 1234–1244, Ju Youn Beak, Hong Soon Kang, Yong-Sik Kim and Anton M Jetten

    Article first published online : 7 MAY 2007, DOI: 10.1359/jbmr.070503

  2. You have full text access to this OnlineOpen article
    Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines

    EMBO Molecular Medicine

    Volume 4, Issue 8, August 2012, Pages: 791–807, Kuo-Pao Lai, Shinichi Yamashita, Chiung-Kuei Huang, Shuyuan Yeh and Chawnshang Chang

    Article first published online : 29 JUN 2012, DOI: 10.1002/emmm.201101140

  3. You have full text access to this OnlineOpen article
    Lis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviour

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 591–607, Anamaria Sudarov, Frank Gooden, Debbie Tseng, Wen-Biao Gan and Margaret Elizabeth Ross

    Article first published online : 11 MAR 2013, DOI: 10.1002/emmm.201202106

  4. You have full text access to this OnlineOpen article
    p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

    EMBO Molecular Medicine

    Volume 2, Issue 11, November 2010, Pages: 472–486, Alicia M. Cole, Rachel A. Ridgway, Sahra E. Derkits, Lee Parry, Nick Barker, Hans Clevers, Alan R. Clarke and Owen J. Sansom

    Article first published online : 26 OCT 2010, DOI: 10.1002/emmm.201000101

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    Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

    EMBO Molecular Medicine

    Volume 4, Issue 8, August 2012, Pages: 705–718, Victoria L. Haley, David J. Barnes, Ionel Sandovici, Miguel Constancia, Christopher F. Graham, Francesco Pezzella, Claudia Bühnemann, Emma J. Carter and A. Bassim Hassan

    Article first published online : 6 JUN 2012, DOI: 10.1002/emmm.201101105

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    Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 259–274, Emmanuel Denou, Karine Lolmède, Lucile Garidou, Celine Pomie, Chantal Chabo, Trevor C Lau, Morgan D Fullerton, Giulia Nigro, Alexia Zakaroff-Girard, Elodie Luche, Céline Garret, Matteo Serino, Jacques Amar, Michael Courtney, Joseph F Cavallari, Brandyn D Henriksbo, Nicole G Barra, Kevin P Foley, Joseph B McPhee, Brittany M Duggan, Hayley M O'Neill, Amanda J Lee, Philippe Sansonetti, Ali A Ashkar, Waliul I Khan, Michael G Surette, Anne Bouloumié, Gregory R Steinberg, Rémy Burcelin and Jonathan D Schertzer

    Article first published online : 9 FEB 2015, DOI: 10.15252/emmm.201404169

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    PHD2 regulates arteriogenic macrophages through TIE2 signalling

    EMBO Molecular Medicine

    Volume 5, Issue 6, June 2013, Pages: 843–857, Alexander Hamm, Lorenzo Veschini, Yukiji Takeda, Sandra Costa, Estelle Delamarre, Mario Leonardo Squadrito, Anne-Theres Henze, Mathias Wenes, Jens Serneels, Ferdinando Pucci, Carmen Roncal, Andrey Anisimov, Kari Alitalo, Michele De Palma and Massimiliano Mazzone

    Article first published online : 25 APR 2013, DOI: 10.1002/emmm.201302695

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    A myelin gene causative of a catatonia-depression syndrome upon aging

    EMBO Molecular Medicine

    Volume 4, Issue 6, June 2012, Pages: 528–539, Nora Hagemeyer, Sandra Goebbels, Sergi Papiol, Anne Kästner, Sabine Hofer, Martin Begemann, Ulrike C. Gerwig, Susann Boretius, Georg L. Wieser, Anja Ronnenberg, Artem Gurvich, Stephan H. Heckers, Jens Frahm, Klaus-Armin Nave and Hannelore Ehrenreich

    Article first published online : 4 APR 2012, DOI: 10.1002/emmm.201200230

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    SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis

    EMBO Molecular Medicine

    Volume 4, Issue 8, August 2012, Pages: 776–790, Meiling Gao, Rachana Patel, Imran Ahmad, Janis Fleming, Joanne Edwards, Stuart McCracken, Kanagasabai Sahadevan, Morag Seywright, Jim Norman, Owen Sansom and Hing Y. Leung

    Article first published online : 31 MAY 2012, DOI: 10.1002/emmm.201100944

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    Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 43–56, Stephan Wueest, Rouven Mueller, Matthias Blüher, Flurin Item, Annie S H Chin, Michael S F Wiedemann, Hitoshi Takizawa, Larisa Kovtonyuk, Alexander V Chervonsky, Eugen J Schoenle, Markus G Manz and Daniel Konrad

    Article first published online : 6 NOV 2013, DOI: 10.1002/emmm.201302962

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    Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 633–646, Rongxue Wu, Eugene Wyatt, Kusum Chawla, Minh Tran, Mohsen Ghanefar, Markku Laakso, Conrad L. Epting and Hossein Ardehali

    Article first published online : 20 APR 2012, DOI: 10.1002/emmm.201200240

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    Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 660–673, Francesc X. Guix, Tina Wahle, Kristel Vennekens, An Snellinx, Lucía Chávez-Gutiérrez, Gerard Ill-Raga, Eva Ramos-Fernandez, Cristina Guardia-Laguarta, Alberto Lleó, Muriel Arimon, Oksana Berezovska, Francisco J. Muñoz, Carlos G. Dotti and Bart De Strooper

    Article first published online : 2 MAY 2012, DOI: 10.1002/emmm.201200243

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    The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 670–687, Marta Luna-Sánchez, Elena Díaz-Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla-García, Enrique Javier Cobos, Germaine Escames, Dario Acuña-Castroviejo, Catarina M Quinzii and Luis Carlos López

    Article first published online : 23 MAR 2015, DOI: 10.15252/emmm.201404632

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    A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1322–1334, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez-Zapico and Min Li

    Article first published online : 16 JUL 2013, DOI: 10.1002/emmm.201302507

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    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Article first published online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

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    Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 394–410, Harsha D Devalla, Verena Schwach, John W Ford, James T Milnes, Said El-Haou, Claire Jackson, Konstantinos Gkatzis, David A Elliott, Susana M Chuva de Sousa Lopes, Christine L Mummery, Arie O Verkerk and Robert Passier

    Article first published online : 19 FEB 2015, DOI: 10.15252/emmm.201404757

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    Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer

    EMBO Molecular Medicine

    Volume 3, Issue 8, August 2011, Pages: 451–464, Wendy WeiJia Soon, Lance David Miller, Michael A. Black, Cyril Dalmasso, Xiu Bin Chan, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Kartiki V. Desai and Edison T. Liu

    Article first published online : 8 JUN 2011, DOI: 10.1002/emmm.201100150

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    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Article first published online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

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    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Article first published online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

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    Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1072–1086, Larissa Cardilo-Reis, Sabrina Gruber, Sabine M. Schreier, Maik Drechsler, Nikolina Papac-Milicevic, Christian Weber, Oswald Wagner, Herbert Stangl, Oliver Soehnlein and Christoph J. Binder

    Article first published online : 2 OCT 2012, DOI: 10.1002/emmm.201201374