Search Results

There are 12438 results for: content related to: The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

  1. You have full text access to this OnlineOpen article
    Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

    EMBO Molecular Medicine

    Volume 2, Issue 9, September 2010, Pages: 349–370, Stephen J. McConoughey, Manuela Basso, Zoya V. Niatsetskaya, Sama F. Sleiman, Natalia A. Smirnova, Brett C. Langley, Lata Mahishi, Arthur J. L. Cooper, Marc A. Antonyak, Rick A. Cerione, Bo Li, Anatoly Starkov, Rajnish Kumar Chaturvedi, M. Flint Beal, Giovanni Coppola, Daniel H. Geschwind, Hoon Ryu, Li Xia, Siiri E. Iismaa, Judit Pallos, Ralf Pasternack, Martin Hils, Jing Fan, Lynn A. Raymond, J. Lawrence Marsh, Leslie M. Thompson and Rajiv R. Ratan

    Article first published online : 1 SEP 2010, DOI: 10.1002/emmm.201000084

  2. You have full text access to this OnlineOpen article
    Déjà vu with a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's disease

    EMBO Molecular Medicine

    Volume 2, Issue 9, September 2010, Pages: 335–337, Parsa Kazemi-Esfarjani and Albert R. La Spada

    Article first published online : 20 AUG 2010, DOI: 10.1002/emmm.201000092

  3. You have full text access to this OnlineOpen article
    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 519–538, Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg and Massimo Loda

    Article first published online : 4 FEB 2014, DOI: 10.1002/emmm.201302734

  4. You have free access to this content
    Differential vulnerability of neurons in Huntington’s disease: the role of cell type-specific features

    Journal of Neurochemistry

    Volume 113, Issue 5, June 2010, Pages: 1073–1091, Ina Han, YiMei You, Jeffrey H. Kordower, Scott T. Brady and Gerardo A. Morfini

    Article first published online : 17 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06672.x

  5. You have full text access to this OnlineOpen article
    Towards a new combination therapy for tuberculosis with next generation benzothiazinones

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 372–383, Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van der Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson and Stewart T Cole

    Article first published online : 5 FEB 2014, DOI: 10.1002/emmm.201303575

  6. You have full text access to this OnlineOpen article
    ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 278–294, Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M. McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch and Gail E Sonenshein

    Article first published online : 27 DEC 2013, DOI: 10.1002/emmm.201303373

  7. You have full text access to this OnlineOpen article
    Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 120–140, Ju Cao, Dongsheng Wang, Fang Xu, Yi Gong, Hong Wang, Zixin Song, Dageng Li, Hua Zhang, Dairong Li, Liping Zhang, Yun Xia, Huajian Xu, Xaiofei Lai, Shihui Lin, Xuemei Zhang, Guosheng Ren, Yubing Dai and Yibing Yin

    Article first published online : 29 OCT 2013, DOI: 10.1002/emmm.201302890

  8. You have full text access to this OnlineOpen article
    The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy

    EMBO Molecular Medicine

    Conor McCloskey, Cara Rada, Elizabeth Bailey, Samantha McCavera, Hugo A van den Berg, Jolene Atia, David A Rand, Anatoly Shmygol, Yi-Wah Chan, Siobhan Quenby, Jan J Brosens, Manu Vatish, Jie Zhang, Jerod S Denton, Michael J Taggart, Catherine Kettleborough, David Tickle, Jeff Jerman, Paul Wright, Timothy Dale, Srinivasan Kanumilli, Derek J Trezise, Steve Thornton, Pamela Brown, Roberto Catalano, Nan Lin, Sarah K England and Andrew M Blanks

    Article first published online : 23 JUL 2014, DOI: 10.15252/emmm.201403944

  9. You have full text access to this OnlineOpen article
    SIL1, a causative cochaperone gene of Marinesco-Sjögren syndrome, plays an essential role in establishing the architecture of the developing cerebral cortex

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 414–429, Yutaka Inaguma, Nanako Hamada, Hidenori Tabata, Ikuko Iwamoto, Makoto Mizuno, Yoshiaki V Nishimura, Hidenori Ito, Rika Morishita, Motomasa Suzuki, Kinji Ohno, Toshiyuki Kumagai and Koh-ichi Nagata

    Article first published online : 29 JAN 2014, DOI: 10.1002/emmm.201303069

  10. You have full text access to this OnlineOpen article
    Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 239–258, Monica Giannotta, Sara Benedetti, Francesco Saverio Tedesco, Monica Corada, Marianna Trani, Rocco D'Antuono, Queensta Millet, Fabrizio Orsenigo, Beatriz G Gálvez, Giulio Cossu and Elisabetta Dejana

    Article first published online : 30 DEC 2013, DOI: 10.1002/emmm.201302520

  11. You have full text access to this OnlineOpen article
    Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction

    EMBO Molecular Medicine

    Volume 6, Issue 6, June 2014, Pages: 760–777, Konstantinos Malliaras, Ahmed Ibrahim, Eleni Tseliou, Weixin Liu, Baiming Sun, Ryan C Middleton, Jeffrey Seinfeld, Lai Wang, Behrooz G Sharifi and Eduardo Marbán

    Article first published online : 5 MAY 2014, DOI: 10.1002/emmm.201303626

  12. You have full text access to this OnlineOpen article
    The unfolded protein response affects readthrough of premature termination codons

    EMBO Molecular Medicine

    Volume 6, Issue 5, May 2014, Pages: 685–701, Yifat S Oren, Michelle L McClure, Steven M Rowe, Eric J Sorscher, Assaf C Bester, Miriam Manor, Eitan Kerem, Joseph Rivlin, Fouad Zahdeh, Matthias Mann, Tamar Geiger and Batsheva Kerem

    Article first published online : 4 APR 2014, DOI: 10.1002/emmm.201303347

  13. You have full text access to this OnlineOpen article
    A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

    EMBO Molecular Medicine

    Volume 6, Issue 7, July 2014, Pages: 882–901, Arnaud Duquet, Alice Melotti, Sonakshi Mishra, Monica Malerba, Chandan Seth, Arwen Conod and Ariel Ruiz i Altaba

    Article first published online : 11 JUN 2014, DOI: 10.15252/emmm.201303799

  14. You have full text access to this OnlineOpen article
    R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5

    EMBO Molecular Medicine

    Volume 5, Issue 5, May 2013, Pages: 776–794, Mariangela Cavarelli, Chiara Foglieni, Maria Rescigno and Gabriella Scarlatti

    Article first published online : 22 APR 2013, DOI: 10.1002/emmm.201202232

  15. You have full text access to this OnlineOpen article
    Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 43–56, Stephan Wueest, Rouven Mueller, Matthias Blüher, Flurin Item, Annie S H Chin, Michael S F Wiedemann, Hitoshi Takizawa, Larisa Kovtonyuk, Alexander V Chervonsky, Eugen J Schoenle, Markus G Manz and Daniel Konrad

    Article first published online : 6 NOV 2013, DOI: 10.1002/emmm.201302962

  16. You have full text access to this OnlineOpen article
    Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 384–397, Sabyasachi Bhattacharya, Kanstantsin V Katlinski, Maximilian Reichert, Shigetsugu Takano, Angela Brice, Bin Zhao, Qiujing Yu, Hui Zheng, Christopher J Carbone, Yuliya V Katlinskaya, N Adrian Leu, Kelly A McCorkell, Satish Srinivasan, Melanie Girondo, Hallgeir Rui, Michael J May, Narayan G Avadhani, Anil K Rustgi and Serge Y Fuchs

    Article first published online : 31 JAN 2014, DOI: 10.1002/emmm.201303236

  17. You have full text access to this OnlineOpen article
    Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 482–495, Jason A Magida and Leslie A Leinwand

    Article first published online : 24 FEB 2014, DOI: 10.1002/emmm.201302852

  18. You have full text access to this OnlineOpen article
    Effective delivery of large genes to the retina by dual AAV vectors

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 194–211, Ivana Trapani, Pasqualina Colella, Andrea Sommella, Carolina Iodice, Giulia Cesi, Sonia de Simone, Elena Marrocco, Settimio Rossi, Massimo Giunti, Arpad Palfi, Gwyneth J Farrar, Roman Polishchuk and Alberto Auricchio

    Article first published online : 16 DEC 2013, DOI: 10.1002/emmm.201302948

  19. You have full text access to this OnlineOpen article
    FGF23 regulates renal sodium handling and blood pressure

    EMBO Molecular Medicine

    Volume 6, Issue 6, June 2014, Pages: 744–759, Olena Andrukhova, Svetlana Slavic, Alina Smorodchenko, Ute Zeitz, Victoria Shalhoub, Beate Lanske, Elena E Pohl and Reinhold G Erben

    Article first published online : 5 MAY 2014, DOI: 10.1002/emmm.201303716

  20. You have full text access to this OnlineOpen article
    Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 467–481, Stacey J Coleman, Athina-Myrto Chioni, Mohammed Ghallab, Rhys K Anderson, Nicholas R Lemoine, Hemant M Kocher and Richard P Grose

    Article first published online : 6 FEB 2014, DOI: 10.1002/emmm.201302698