Search Results

There are 3600 results for: content related to: Activation of rapid oestrogen signalling in aggressive human breast cancers

  1. You have full text access to this OnlineOpen article
    The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

    EMBO Molecular Medicine

    Volume 7, Issue 11, November 2015, Pages: 1426–1449, Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis and Cheng Wang

    Article first published online : 28 SEP 2015, DOI: 10.15252/emmm.201404976

  2. You have full text access to this OnlineOpen article
    Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

    EMBO Molecular Medicine

    Volume 7, Issue 7, July 2015, Pages: 950–972, Floriana Centritto, Gabriela Paroni, Marco Bolis, Silvio Ken Garattini, Mami Kurosaki, Maria Monica Barzago, Adriana Zanetti, James Neil Fisher, Mark Francis Scott, Linda Pattini, Monica Lupi, Paolo Ubezio, Francesca Piccotti, Alberto Zambelli, Paola Rizzo, Maurizio Gianni', Maddalena Fratelli, Mineko Terao and Enrico Garattini

    Article first published online : 17 APR 2015, DOI: 10.15252/emmm.201404670

  3. You have full text access to this OnlineOpen article
    The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 670–687, Marta Luna-Sánchez, Elena Díaz-Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla-García, Enrique Javier Cobos, Germaine Escames, Dario Acuña-Castroviejo, Catarina M Quinzii and Luis Carlos López

    Article first published online : 23 MAR 2015, DOI: 10.15252/emmm.201404632

  4. You have full text access to this OnlineOpen article
    A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1322–1334, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez-Zapico and Min Li

    Article first published online : 16 JUL 2013, DOI: 10.1002/emmm.201302507

  5. You have full text access to this OnlineOpen article
    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Article first published online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

  6. You have full text access to this OnlineOpen article
    Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 394–410, Harsha D Devalla, Verena Schwach, John W Ford, James T Milnes, Said El-Haou, Claire Jackson, Konstantinos Gkatzis, David A Elliott, Susana M Chuva de Sousa Lopes, Christine L Mummery, Arie O Verkerk and Robert Passier

    Article first published online : 19 FEB 2015, DOI: 10.15252/emmm.201404757

  7. You have full text access to this OnlineOpen article
    Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer

    EMBO Molecular Medicine

    Volume 3, Issue 8, August 2011, Pages: 451–464, Wendy WeiJia Soon, Lance David Miller, Michael A. Black, Cyril Dalmasso, Xiu Bin Chan, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Kartiki V. Desai and Edison T. Liu

    Article first published online : 8 JUN 2011, DOI: 10.1002/emmm.201100150

  8. You have full text access to this OnlineOpen article
    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Article first published online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

  9. You have full text access to this OnlineOpen article
    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Article first published online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

  10. You have full text access to this OnlineOpen article
    Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1072–1086, Larissa Cardilo-Reis, Sabrina Gruber, Sabine M. Schreier, Maik Drechsler, Nikolina Papac-Milicevic, Christian Weber, Oswald Wagner, Herbert Stangl, Oliver Soehnlein and Christoph J. Binder

    Article first published online : 2 OCT 2012, DOI: 10.1002/emmm.201201374

  11. You have full text access to this OnlineOpen article
    mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue

    EMBO Molecular Medicine

    Verena Albert, Kristoffer Svensson, Mitsugu Shimobayashi, Marco Colombi, Sergio Muñoz, Veronica Jimenez, Christoph Handschin, Fatima Bosch and Michael N Hall

    Article first published online : 15 JAN 2016, DOI: 10.15252/emmm.201505610

  12. You have full text access to this OnlineOpen article
    Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

    EMBO Molecular Medicine

    Volume 7, Issue 6, June 2015, Pages: 695–713, Kevin White, Yu Lu, Sofia Annis, Andrew E Hale, B Nelson Chau, James E Dahlman, Craig Hemann, Alexander R Opotowsky, Sara O Vargas, Ivan Rosas, Mark A Perrella, Juan C Osorio, Kathleen J Haley, Brian B Graham, Rahul Kumar, Rajan Saggar, Rajeev Saggar, W Dean Wallace, David J Ross, Omar F Khan, Andrew Bader, Bernadette R Gochuico, Majed Matar, Kevin Polach, Nicolai M Johannessen, Haydn M Prosser, Daniel G Anderson, Robert Langer, Jay L Zweier, Laurence A Bindoff, David Systrom, Aaron B Waxman, Richard C Jin and Stephen Y Chan

    Article first published online : 30 MAR 2015, DOI: 10.15252/emmm.201404511

  13. You have full text access to this OnlineOpen article
    The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1126–1143, Sayan Chowdhury, Tulika Mukherjee, Rupkatha Mukhopadhyay, Budhaditya Mukherjee, Souvik Sengupta, Sharmila Chattopadhyay, Parasuraman Jaisankar, Syamal Roy and Hemanta K. Majumder

    Article first published online : 2 OCT 2012, DOI: 10.1002/emmm.201201316

  14. You have full text access to this OnlineOpen article
    Towards a new combination therapy for tuberculosis with next generation benzothiazinones

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 372–383, Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van der Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson and Stewart T Cole

    Article first published online : 5 FEB 2014, DOI: 10.1002/emmm.201303575

  15. You have full text access to this OnlineOpen article
    Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 149–166, Yan Liu, Oriana E. Hawkins, Yingjun Su, Anna E. Vilgelm, Tammy Sobolik, Yee-Mon Thu, Sara Kantrow, Ryan C. Splittgerber, Sarah Short, Katayoun I. Amiri, Jeffery A. Ecsedy, Jeffery A. Sosman, Mark C. Kelley and Ann Richmond

    Article first published online : 25 NOV 2012, DOI: 10.1002/emmm.201201378

  16. You have full text access to this OnlineOpen article
    Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 608–627, Joan Castellsagué, Bernat Gel, Juana Fernández-Rodríguez, Roger Llatjós, Ignacio Blanco, Yolanda Benavente, Diana Pérez-Sidelnikova, Javier García-del Muro, Joan Maria Viñals, August Vidal, Rafael Valdés-Mas, Ernest Terribas, Adriana López-Doriga, Miguel Angel Pujana, Gabriel Capellá, Xose S Puente, Eduard Serra, Alberto Villanueva and Conxi Lázaro

    Article first published online : 25 MAR 2015, DOI: 10.15252/emmm.201404430

  17. You have full text access to this OnlineOpen article
    Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

    EMBO Molecular Medicine

    Volume 7, Issue 9, September 2015, Pages: 1229–1243, Megan V Cannon, Herman HW Silljé, Jürgen WA Sijbesma, Inge Vreeswijk-Baudoin, Jolita Ciapaite, Bart van der Sluis, Jan van Deursen, Gustavo JJ Silva, Leon J de Windt, Jan-Åke Gustafsson, Pim van der Harst, Wiek H van Gilst and Rudolf A de Boer

    Article first published online : 14 JUL 2015, DOI: 10.15252/emmm.201404669

  18. You have full text access to this OnlineOpen article
    ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 278–294, Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M. McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch and Gail E Sonenshein

    Article first published online : 27 DEC 2013, DOI: 10.1002/emmm.201303373

  19. You have full text access to this OnlineOpen article
    A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

    EMBO Molecular Medicine

    Volume 4, Issue 11, November 2012, Pages: 1156–1175, Serena Marchiò, Marco Soster, Sabrina Cardaci, Andrea Muratore, Alice Bartolini, Vanessa Barone, Dario Ribero, Maria Monti, Paola Bovino, Jessica Sun, Raffaella Giavazzi, Sofia Asioli, Paola Cassoni, Lorenzo Capussotti, Piero Pucci, Antonella Bugatti, Marco Rusnati, Renata Pasqualini, Wadih Arap and Federico Bussolino

    Article first published online : 16 OCT 2012, DOI: 10.1002/emmm.201101164

  20. You have full text access to this OnlineOpen article
    Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 339–356, Agnes Lau, Alex McDonald, Nathalie Daude, Charles E Mays, Eric D Walter, Robin Aglietti, Robert CC Mercer, Serene Wohlgemuth, Jacques van der Merwe, Jing Yang, Hristina Gapeshina, Chae Kim, Jennifer Grams, Beipei Shi, Holger Wille, Aru Balachandran, Gerold Schmitt-Ulms, Jiri G Safar, Glenn L Millhauser and David Westaway

    Article first published online : 6 FEB 2015, DOI: 10.15252/emmm.201404588