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There are 9910 results for: content related to: Actin filament dynamics impacts keratinocyte stem cell maintenance

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    A single epidermal stem cell strategy for safe ex vivo gene therapy

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 380–393, Stéphanie Droz-Georget Lathion, Ariane Rochat, Graham Knott, Alessandra Recchia, Danielle Martinet, Sara Benmohammed, Nicolas Grasset, Andrea Zaffalon, Nathalie Besuchet Schmutz, Emmanuelle Savioz-Dayer, Jacques Samuel Beckmann, Jacques Rougemont, Fulvio Mavilio and Yann Barrandon

    Version of Record online : 27 FEB 2015, DOI: 10.15252/emmm.201404353

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    The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

    EMBO Molecular Medicine

    Volume 7, Issue 11, November 2015, Pages: 1426–1449, Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis and Cheng Wang

    Version of Record online : 28 SEP 2015, DOI: 10.15252/emmm.201404976

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    The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 670–687, Marta Luna-Sánchez, Elena Díaz-Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla-García, Enrique Javier Cobos, Germaine Escames, Dario Acuña-Castroviejo, Catarina M Quinzii and Luis Carlos López

    Version of Record online : 23 MAR 2015, DOI: 10.15252/emmm.201404632

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    A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1322–1334, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez-Zapico and Min Li

    Version of Record online : 16 JUL 2013, DOI: 10.1002/emmm.201302507

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    Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid

    EMBO Molecular Medicine

    Volume 5, Issue 9, September 2013, Pages: 1443–1457, Cathal McCarthy, Nora T. Lieggi, Denis Barry, Declan Mooney, Monica de Gaetano, William G. James, Sarah McClelland, Mary C. Barry, Laure Escoubet-Lozach, Andrew C. Li, Christopher K Glass, Desmond J. Fitzgerald and Orina Belton

    Version of Record online : 21 AUG 2013, DOI: 10.1002/emmm.201302587

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    Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

    EMBO Molecular Medicine

    Volume 7, Issue 4, April 2015, Pages: 394–410, Harsha D Devalla, Verena Schwach, John W Ford, James T Milnes, Said El-Haou, Claire Jackson, Konstantinos Gkatzis, David A Elliott, Susana M Chuva de Sousa Lopes, Christine L Mummery, Arie O Verkerk and Robert Passier

    Version of Record online : 19 FEB 2015, DOI: 10.15252/emmm.201404757

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    Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer

    EMBO Molecular Medicine

    Volume 3, Issue 8, August 2011, Pages: 451–464, Wendy WeiJia Soon, Lance David Miller, Michael A. Black, Cyril Dalmasso, Xiu Bin Chan, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Kartiki V. Desai and Edison T. Liu

    Version of Record online : 8 JUN 2011, DOI: 10.1002/emmm.201100150

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    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Version of Record online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

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    Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

    EMBO Molecular Medicine

    Volume 7, Issue 2, February 2015, Pages: 140–157, Cao Dan, Bian Jinjun, Hua Zi-Chun, Ma Lin, Chen Wei, Zhang Xu, Zhou Ri, Cheng Shun, Sun Wen-Zhu, Jiao Qing-Cai and Yin Wu

    Version of Record online : 22 DEC 2014, DOI: 10.15252/emmm.201404797

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    SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

    EMBO Molecular Medicine

    Volume 8, Issue 9, September 2016, Pages: 1019–1038, Alexandre Janer, Julien Prudent, Vincent Paupe, Somayyeh Fahiminiya, Jacek Majewski, Nicolas Sgarioto, Christine Des Rosiers, Anik Forest, Zhen-Yuan Lin, Anne-Claude Gingras, Grant Mitchell, Heidi M McBride and Eric A Shoubridge

    Version of Record online : 7 JUL 2016, DOI: 10.15252/emmm.201506159

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    mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue

    EMBO Molecular Medicine

    Volume 8, Issue 3, March 2016, Pages: 232–246, Verena Albert, Kristoffer Svensson, Mitsugu Shimobayashi, Marco Colombi, Sergio Muñoz, Veronica Jimenez, Christoph Handschin, Fatima Bosch and Michael N Hall

    Version of Record online : 15 JAN 2016, DOI: 10.15252/emmm.201505610

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    Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

    EMBO Molecular Medicine

    Volume 7, Issue 6, June 2015, Pages: 695–713, Kevin White, Yu Lu, Sofia Annis, Andrew E Hale, B Nelson Chau, James E Dahlman, Craig Hemann, Alexander R Opotowsky, Sara O Vargas, Ivan Rosas, Mark A Perrella, Juan C Osorio, Kathleen J Haley, Brian B Graham, Rahul Kumar, Rajan Saggar, Rajeev Saggar, W Dean Wallace, David J Ross, Omar F Khan, Andrew Bader, Bernadette R Gochuico, Majed Matar, Kevin Polach, Nicolai M Johannessen, Haydn M Prosser, Daniel G Anderson, Robert Langer, Jay L Zweier, Laurence A Bindoff, David Systrom, Aaron B Waxman, Richard C Jin and Stephen Y Chan

    Version of Record online : 30 MAR 2015, DOI: 10.15252/emmm.201404511

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    The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice

    EMBO Molecular Medicine

    Volume 4, Issue 10, October 2012, Pages: 1126–1143, Sayan Chowdhury, Tulika Mukherjee, Rupkatha Mukhopadhyay, Budhaditya Mukherjee, Souvik Sengupta, Sharmila Chattopadhyay, Parasuraman Jaisankar, Syamal Roy and Hemanta K. Majumder

    Version of Record online : 2 OCT 2012, DOI: 10.1002/emmm.201201316

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    Towards a new combination therapy for tuberculosis with next generation benzothiazinones

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 372–383, Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van der Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson and Stewart T Cole

    Version of Record online : 5 FEB 2014, DOI: 10.1002/emmm.201303575

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    Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases

    EMBO Molecular Medicine

    Volume 8, Issue 11, November 2016, Pages: 1265–1288, Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Chui Ming Gemmy Cheung, Sai Bo Bo Tun, Yeo Sia Wey, Daiju Iwata, Miroslav Dostalek, Jörg Moelleken, Kay G Stubenrauch, Everson Nogoceke, Gabriella Widmer, Pamela Strassburger, Michael J Koss, Christian Klein, David T Shima and Guido Hartmann

    Version of Record online : 14 OCT 2016, DOI: 10.15252/emmm.201505889

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    A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases

    EMBO Molecular Medicine

    Volume 8, Issue 6, June 2016, Pages: 609–625, Jakob Körbelin, Godwin Dogbevia, Stefan Michelfelder, Dirk A Ridder, Agnes Hunger, Jan Wenzel, Henning Seismann, Melanie Lampe, Jacqueline Bannach, Manolis Pasparakis, Jürgen A Kleinschmidt, Markus Schwaninger and Martin Trepel

    Version of Record online : 22 APR 2016, DOI: 10.15252/emmm.201506078

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    Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence

    EMBO Molecular Medicine

    Volume 5, Issue 1, January 2013, Pages: 149–166, Yan Liu, Oriana E. Hawkins, Yingjun Su, Anna E. Vilgelm, Tammy Sobolik, Yee-Mon Thu, Sara Kantrow, Ryan C. Splittgerber, Sarah Short, Katayoun I. Amiri, Jeffery A. Ecsedy, Jeffery A. Sosman, Mark C. Kelley and Ann Richmond

    Version of Record online : 25 NOV 2012, DOI: 10.1002/emmm.201201378

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    Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine

    EMBO Molecular Medicine

    Volume 7, Issue 5, May 2015, Pages: 608–627, Joan Castellsagué, Bernat Gel, Juana Fernández-Rodríguez, Roger Llatjós, Ignacio Blanco, Yolanda Benavente, Diana Pérez-Sidelnikova, Javier García-del Muro, Joan Maria Viñals, August Vidal, Rafael Valdés-Mas, Ernest Terribas, Adriana López-Doriga, Miguel Angel Pujana, Gabriel Capellá, Xose S Puente, Eduard Serra, Alberto Villanueva and Conxi Lázaro

    Version of Record online : 25 MAR 2015, DOI: 10.15252/emmm.201404430

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    Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

    EMBO Molecular Medicine

    Volume 7, Issue 9, September 2015, Pages: 1229–1243, Megan V Cannon, Herman HW Silljé, Jürgen WA Sijbesma, Inge Vreeswijk-Baudoin, Jolita Ciapaite, Bart van der Sluis, Jan van Deursen, Gustavo JJ Silva, Leon J de Windt, Jan-Åke Gustafsson, Pim van der Harst, Wiek H van Gilst and Rudolf A de Boer

    Version of Record online : 14 JUL 2015, DOI: 10.15252/emmm.201404669

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    ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 278–294, Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M. McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch and Gail E Sonenshein

    Version of Record online : 27 DEC 2013, DOI: 10.1002/emmm.201303373