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There are 12923 results for: content related to: Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

  1. You have free access to this content
    Farnesylation of Ras is important for the interaction with phosphoinositide 3-kinase γ

    European Journal of Biochemistry

    Volume 266, Issue 1, November (II) 1999, Pages: 70–82, Ignacio Rubio, Ute Wittig, Claudia Meyer, Regina Heinze, Dieter Kadereit, Herbert Waldmann, Julian Downward and Reinhard Wetzker

    Version of Record online : 25 DEC 2001, DOI: 10.1046/j.1432-1327.1999.00815.x

  2. Dynamics of GFP-Fusion p110α and p110β Isoforms of PI3K Signaling Pathway in Normal and Cancer Cells

    Journal of Cellular Biochemistry

    Volume 117, Issue 12, December 2016, Pages: 2864–2874, Paramjeet Singh, Mohd Saleem Dar, Gurjinder Singh, Gayatri Jamwal, Parduman Raj Sharma, Muzamil Ahmad and Mohd Jamal Dar

    Version of Record online : 3 JUN 2016, DOI: 10.1002/jcb.25598

  3. Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts

    Journal of Bone and Mineral Research

    Volume 31, Issue 8, August 2016, Pages: 1617–1630, Beatriz Gámez, Edgardo Rodríguez-Carballo, Mariona Graupera, José Luis Rosa and Francesc Ventura

    Version of Record online : 15 MAR 2016, DOI: 10.1002/jbmr.2819

  4. You have free access to this content
    Engineering of an isolated p110α subunit of PI3Kα permits crystallization and provides a platform for structure-based drug design

    Protein Science

    Volume 23, Issue 10, October 2014, Pages: 1332–1340, Ping Chen, Ya-Li Deng, Simon Bergqvist, Matthew D. Falk, Wei Liu, Sergei Timofeevski and Alexei Brooun

    Version of Record online : 7 AUG 2014, DOI: 10.1002/pro.2517

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    p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?

    FEBS Letters

    Volume 590, Issue 18, September 2016, Pages: 3071–3082, Paramjeet Singh, Mohd Saleem Dar and Mohd Jamal Dar

    Version of Record online : 12 SEP 2016, DOI: 10.1002/1873-3468.12377

  6. You have free access to this content
    Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

    The EMBO Journal

    Volume 18, Issue 5, March 1, 1999, Pages: 1292–1302, Bart Vanhaesebroeck, Kyochiro Higashi, Catherine Raven, Melanie Welham, Simon Anderson, Paul Brennan, Stephen G. Ward and Michael D. Waterfield

    Version of Record online : 1 MAR 1999, DOI: 10.1093/emboj/18.5.1292

  7. You have free access to this content
    PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

    International Journal of Cancer

    Volume 130, Issue 11, 1 June 2012, Pages: 2505–2513, Francesco Dituri, Antonio Mazzocca, Luigi Lupo, Charlotte E. Edling, Amalia Azzariti, Salvatore Antonaci, Marco Falasca and Gianluigi Giannelli

    Version of Record online : 24 JAN 2012, DOI: 10.1002/ijc.26319

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    Evading inhibitory constraints – destabilizing p110α/p85α interactions

    The FEBS Journal

    Volume 282, Issue 18, September 2015, Pages: 3525–3527, Clare Sheridan

    Version of Record online : 25 AUG 2015, DOI: 10.1111/febs.13392

  9. You have free access to this content
    Emerging common themes in regulation of PIKKs and PI3Ks

    The EMBO Journal

    Volume 28, Issue 20, October 21, 2009, Pages: 3067–3073, Harri Lempiäinen and Thanos D Halazonetis

    Version of Record online : 24 SEP 2009, DOI: 10.1038/emboj.2009.281

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    Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α

    The FEBS Journal

    Volume 282, Issue 18, September 2015, Pages: 3528–3542, Ignacia Echeverria, Yunlong Liu, Sandra B. Gabelli and L. Mario Amzel

    Version of Record online : 24 JUL 2015, DOI: 10.1111/febs.13365

  11. Phosphatidylinositol-3,4,5-trisphosphate: Tool of choice for class I PI 3-kinases


    Volume 35, Issue 7, July 2013, Pages: 602–611, Rachel Schnur Salamon and Jonathan M. Backer

    Version of Record online : 13 JUN 2013, DOI: 10.1002/bies.201200176

  12. The phosphoinositide 3′-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle

    Journal of Cellular Physiology

    Volume 227, Issue 8, August 2012, Pages: 3044–3052, Qi Ge, Lyn M. Moir, Thomas Trian, Kyoko Niimi, Maree Poniris, Peter R. Shepherd, Judith L. Black, Brian G. Oliver and Janette K. Burgess

    Version of Record online : 23 APR 2012, DOI: 10.1002/jcp.23046

  13. Both p110α and p110β Isoforms of Phosphatidylinositol 3-OH-Kinase are Required for Insulin Signalling in the Hypothalamus

    Journal of Neuroendocrinology

    Volume 22, Issue 6, June 2010, Pages: 534–542, A. Tups, G. M. Anderson, M. Rizwan, R. A. Augustine, C. Chaussade, P. R. Shepherd and D. R. Grattan

    Version of Record online : 2 MAR 2010, DOI: 10.1111/j.1365-2826.2010.01975.x

  14. Regulation of angiogenesis and tumor growth by p110 Alpha and AKT1 via VEGF expression

    Journal of Cellular Physiology

    Volume 209, Issue 1, October 2006, Pages: 56–66, Chang Xia, Qiao Meng, Zongxian Cao, Xianglin Shi and Bing-Hua Jiang

    Version of Record online : 14 JUN 2006, DOI: 10.1002/jcp.20707

  15. Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt

    Journal of Cellular Biochemistry

    Volume 95, Issue 5, 1 August 2005, Pages: 979–989, Wolfgang Link, Aranzazu Rosado, Jesus Fominaya, James E. Thomas and Amancio Carnero

    Version of Record online : 18 APR 2005, DOI: 10.1002/jcb.20479

  16. Galanin-Like Peptide (GALP) Neurone-Specific Phosphoinositide 3-Kinase Signalling Regulates GALP mRNA Levels in the Hypothalamus of Males and Luteinising Hormone Levels in Both Sexes

    Journal of Neuroendocrinology

    Volume 26, Issue 7, July 2014, Pages: 426–438, R. Aziz, M. Beymer, A. L. Negrón, A. Newshan, G. Yu, B. Rosati, D. McKinnon, M. Fukuda, R. Z. Lin, C. Mayer, U. Boehm and M. Acosta-Martínez

    Version of Record online : 23 JUN 2014, DOI: 10.1111/jne.12163

  17. Rules of engagement: distinct functions for the four class I PI3K catalytic isoforms in immunity

    Annals of the New York Academy of Sciences

    Volume 1280, Issue 1, March 2013, Pages: 24–26, Klaus Okkenhaug

    Version of Record online : 28 MAR 2013, DOI: 10.1111/nyas.12027

  18. You have full text access to this OnlineOpen article
    Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors

    Cancer Science

    Volume 106, Issue 2, February 2015, Pages: 208–215, Ken Saijo, Jin Imamura, Koichi Narita, Akifumi Oda, Hideki Shimodaira, Tadashi Katoh and Chikashi Ishioka

    Version of Record online : 28 JAN 2015, DOI: 10.1111/cas.12585

  19. Fine tuning the immune response with PI3K

    Immunological Reviews

    Volume 228, Issue 1, March 2009, Pages: 253–272, David A. Fruman and Georges Bismuth

    Version of Record online : 6 MAR 2009, DOI: 10.1111/j.1600-065X.2008.00750.x

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    Induction of apoptosis by p110C requires mitochondrial translocation of the proapoptotic BCL-2 family member BAD

    FEBS Letters

    Volume 580, Issue 3, February 06, 2006, Pages: 813–821, Chen Chen, Jun Yan, Qing Sun, Luyang Yao, Yongzhi Jian, Jieqiong Lu and Jianxin Gu

    Version of Record online : 10 JAN 2006, DOI: 10.1016/j.febslet.2005.12.097