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There are 489 results for: content related to: Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

  1. You have full text access to this OnlineOpen article
    Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency

    EMBO Molecular Medicine

    Volume 5, Issue 3, March 2013, Pages: 397–412, Nunzia Pastore, Keith Blomenkamp, Fabio Annunziata, Pasquale Piccolo, Pratibha Mithbaokar, Rosa Maria Sepe, Francesco Vetrini, Donna Palmer, Philip Ng, Elena Polishchuk, Simona Iacobacci, Roman Polishchuk, Jeffrey Teckman, Andrea Ballabio and Nicola Brunetti-Pierri

    Article first published online : 4 FEB 2013, DOI: 10.1002/emmm.201202046

  2. TDP-43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 121–142, Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying and Guanghui Wang

    Article first published online : 23 DEC 2015, DOI: 10.15252/embj.201591998

  3. TFEB and TFE3 are novel components of the integrated stress response

    The EMBO Journal

    José A Martina, Heba I Diab, Owen A Brady and Rosa Puertollano

    Article first published online : 26 JAN 2016, DOI: 10.15252/embj.201593428

  4. You have full text access to this OnlineOpen article
    Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB

    EMBO Molecular Medicine

    Volume 6, Issue 9, September 2014, Pages: 1142–1160, Vinicia A Polito, Hongmei Li, Heidi Martini-Stoica, Baiping Wang, Li Yang, Yin Xu, Daniel B Swartzlander, Michela Palmieri, Alberto di Ronza, Virginia M-Y Lee, Marco Sardiello, Andrea Ballabio and Hui Zheng

    Article first published online : 28 JUL 2014, DOI: 10.15252/emmm.201303671

  5. You have full text access to this OnlineOpen article
    A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

    The EMBO Journal

    Volume 31, Issue 5, March 7, 2012, Pages: 1095–1108, Carmine Settembre, Roberto Zoncu, Diego L Medina, Francesco Vetrini, Serkan Erdin, SerpilUckac Erdin, Tuong Huynh, Mathieu Ferron, Gerard Karsenty, Michel C Vellard, Valeria Facchinetti, David M Sabatini and Andrea Ballabio

    Article first published online : 17 FEB 2012, DOI: 10.1038/emboj.2012.32

  6. You have full text access to this OnlineOpen article
    Regulation of TFEB and V-ATPases by mTORC1

    The EMBO Journal

    Volume 30, Issue 16, August 17, 2011, Pages: 3242–3258, Samuel Peña-Llopis, Silvia Vega-Rubin-de-Celis, Jacob C Schwartz, Nicholas C Wolff, Tram Anh T Tran, Lihua Zou, Xian-Jin Xie, David R Corey and James Brugarolas

    Article first published online : 29 JUL 2011, DOI: 10.1038/emboj.2011.257

  7. The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway

    Journal of Cellular Physiology

    Erika Yoneshima, Kuniaki Okamoto, Eiko Sakai, Kazuhisa Nishishita, Noriaki Yoshida and Takayuki Tsukuba

    Article first published online : 20 NOV 2015, DOI: 10.1002/jcp.25235

  8. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

    Journal of Neurochemistry

    Volume 136, Issue 2, January 2016, Pages: 388–402, Davor Ivankovic, Kai-Yin Chau, Anthony H. V. Schapira and Matthew E. Gegg

    Article first published online : 24 NOV 2015, DOI: 10.1111/jnc.13412

  9. You have free access to this content
    Transcription factor EB: A central regulator of both the autophagosome and lysosome


    Volume 55, Issue 5, May 2012, Pages: 1632–1634, Enpeng Zhao and Mark J. Czaja

    Article first published online : 19 APR 2012, DOI: 10.1002/hep.25619

  10. You have free access to this content
    Cervical Transforaminal Epidural Block Using Low-Dose Local Anesthetic: A Prospective, Randomized, Double-Blind Study

    Pain Medicine

    Volume 16, Issue 1, January 2015, Pages: 61–67, Jae Hee Woo and Hahck Soo Park

    Article first published online : 7 OCT 2014, DOI: 10.1111/pme.12582

  11. Characterization of t(6;11)(p21;q12) in a renal-cell carcinoma of an adult patient

    Genes, Chromosomes and Cancer

    Volume 46, Issue 5, May 2007, Pages: 419–426, Lorenza Pecciarini, M. Giulia Cangi, Crocifissa Lo Cunsolo, Ettore Macri', Elena Dal Cin, Guido Martignoni and Claudio Doglioni

    Article first published online : 6 FEB 2007, DOI: 10.1002/gcc.20422

  12. You have full text access to this OnlineOpen article
    Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

    Aging Cell

    Volume 14, Issue 2, April 2015, Pages: 249–264, Jaime L. Schneider, Joan Villarroya, Antonio Diaz-Carretero, Bindi Patel, Aleksandra M. Urbanska, Mia M. Thi, Francesc Villarroya, Laura Santambrogio and Ana Maria Cuervo

    Article first published online : 23 JAN 2015, DOI: 10.1111/acel.12310

  13. Transcription factors and cognate signalling cascades in the regulation of autophagy

    Biological Reviews

    Vemika Chandra, Ella Bhagyaraj, Raman Parkesh and Pawan Gupta

    Article first published online : 4 FEB 2015, DOI: 10.1111/brv.12177

  14. You have free access to this content
    Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec

    Developmental Dynamics

    Volume 240, Issue 11, November 2011, Pages: 2529–2538, James A. Lister, Brandon M. Lane, Anhthu Nguyen and Katherine Lunney

    Article first published online : 19 SEP 2011, DOI: 10.1002/dvdy.22743

  15. You have full text access to this OnlineOpen article
    The awesome lysosome

    EMBO Molecular Medicine

    Volume 8, Issue 2, February 2016, Pages: 73–76, Andrea Ballabio

    Article first published online : 19 JAN 2016, DOI: 10.15252/emmm.201505966

  16. Renal carcinoma with (6;11)(p21;q12) translocation: Report of an adult case

    Pathology International

    Volume 61, Issue 9, September 2011, Pages: 539–545, Akira Ishihara, Yasuhiro Yamashita, Hiroki Takamori and Naoto Kuroda

    Article first published online : 7 AUG 2011, DOI: 10.1111/j.1440-1827.2011.02711.x

  17. Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB

    Alcoholism: Clinical and Experimental Research

    Volume 39, Issue 12, December 2015, Pages: 2354–2363, Paul G. Thomes, Casey S. Trambly, Howard S. Fox, Dean J. Tuma and Terrence M. Donohue Jr.

    Article first published online : 11 NOV 2015, DOI: 10.1111/acer.12904

  18. Time-Dependent Effects of Hydrophobic Amine-Containing Drugs on Lysosome Structure and Biogenesis in Cultured Human Fibroblasts

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 10, October 2014, Pages: 3287–3296, Randall Logan, Alex C. Kong and Jeffrey P. Krise

    Article first published online : 16 JUL 2014, DOI: 10.1002/jps.24087

  19. The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation

    EMBO reports

    Koji Yamano, Noriyuki Matsuda and Keiji Tanaka

    Article first published online : 8 FEB 2016, DOI: 10.15252/embr.201541486

  20. You have free access to this content
    TFEBulous control of traffic by mTOR

    The EMBO Journal

    Volume 30, Issue 16, August 17, 2011, Pages: 3215–3216, Estela Jacinto

    Article first published online : 17 AUG 2011, DOI: 10.1038/emboj.2011.258