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There are 8781 results for: content related to: Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

  1. You have free access to this content
    Spinal Muscular Atrophy: From Gene Discovery to Clinical Trials

    Annals of Human Genetics

    Volume 77, Issue 5, September 2013, Pages: 435–463, Dian K. Nurputra, Poh San Lai, Nur Imma F. Harahap, Satoru Morikawa, Tomoto Yamamoto, Noriyuki Nishimura, Yuji Kubo, Atsuko Takeuchi, Toshio Saito, Yasuhiro Takeshima, Yumi Tohyama, Stacey KH Tay, Poh Sim Low, Kayoko Saito and Hisahide Nishio

    Version of Record online : 23 JUL 2013, DOI: 10.1111/ahg.12031

  2. You have full text access to this OnlineOpen article
    Pathological impact of SMN2 mis-splicing in adult SMA mice

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1586–1601, Kentaro Sahashi, Karen K. Y. Ling, Yimin Hua, John Erby Wilkinson, Tomoki Nomakuchi, Frank Rigo, Gene Hung, David Xu, Ya-Ping Jiang, Richard Z. Lin, Chien-Ping Ko, C. Frank Bennett and Adrian R. Krainer

    Version of Record online : 9 SEP 2013, DOI: 10.1002/emmm.201302567

  3. QNQKE targeting motif for the SMN-Gemin multiprotein complexin neurons

    Journal of Neuroscience Research

    Volume 85, Issue 12, September 2007, Pages: 2657–2667, Honglai Zhang, Lei Xing, Robert H. Singer and Gary J. Bassell

    Version of Record online : 23 APR 2007, DOI: 10.1002/jnr.21308

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    Smn deficiency causes neuritogenesis and neurogenesis defects in the retinal neurons of a mouse model of spinal muscular atrophy

    Developmental Neurobiology

    Volume 71, Issue 2, February 2011, Pages: 153–169, Hong Liu, Ariane Beauvais, Adam N. Baker, Catherine Tsilfidis and Rashmi Kothary

    Version of Record online : 7 JAN 2011, DOI: 10.1002/dneu.20840

  5. Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy

    Journal of Neuroscience Research

    Volume 88, Issue 1, January 2010, Pages: 111–122, Hong Liu, Dina Shafey, Justin N. Moores and Rashmi Kothary

    Version of Record online : 29 JUL 2009, DOI: 10.1002/jnr.22189

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    Identification and characterization of the porcine (Sus scrofa) survival motor neuron (SMN1) gene: An animal model for therapeutic studies

    Developmental Dynamics

    Volume 237, Issue 8, August 2008, Pages: 2268–2278, Monique A. Lorson, Lee D. Spate, Randall S. Prather and Christian L. Lorson

    Version of Record online : 23 JUL 2008, DOI: 10.1002/dvdy.21642

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    Spinal muscular atrophy pathogenic mutations impair the axonogenic properties of axonal-survival of motor neuron

    Journal of Neurochemistry

    Volume 121, Issue 3, May 2012, Pages: 465–474, Denise Locatelli, Paolo d’Errico, Silvia Capra, Adele Finardi, Francesca Colciaghi, Veronica Setola, Mineko Terao, Enrico Garattini and Giorgio Battaglia

    Version of Record online : 14 MAR 2012, DOI: 10.1111/j.1471-4159.2012.07689.x

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    Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons

    Developmental Neurobiology

    Volume 74, Issue 3, March 2014, Pages: 319–332, Claudia Fallini, Jeremy P. Rouanet, Paul G. Donlin-Asp, Peng Guo, Honglai Zhang, Robert H. Singer, Wilfried Rossoll and Gary J. Bassell

    Version of Record online : 4 OCT 2013, DOI: 10.1002/dneu.22111

  9. Invertebrate models of spinal muscular atrophy: Insights into mechanisms and potential therapeutics

    BioEssays

    Volume 33, Issue 12, December 2011, Pages: 956–965, Stuart J. Grice, James N. Sleigh, Ji-Long Liu and David B. Sattelle

    Version of Record online : 18 OCT 2011, DOI: 10.1002/bies.201100082

  10. Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated

    European Journal of Neuroscience

    Volume 10, Issue 9, September 1998, Pages: 2913–2923, Vincenzo La Bella, Claire Cisterni, Danièle Salaün and Brigitte Pettmann

    Version of Record online : 15 DEC 2003, DOI: 10.1111/j.1460-9568.1998.00298.x

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    Modulation of alternative splicing by expression of small nuclear ribonucleoprotein polypeptide N

    The FEBS Journal

    Volume 281, Issue 23, December 2014, Pages: 5194–5207, Moon-Sing Lee, Yu-Shan Lin, Yi-Fang Deng, Wan-Ting Hsu, Chiung-Chun Shen, Yi-Hsin Cheng, Yao-Ting Huang and Chin Li

    Version of Record online : 13 OCT 2014, DOI: 10.1111/febs.13059

  12. A large animal model of spinal muscular atrophy and correction of phenotype

    Annals of Neurology

    Volume 77, Issue 3, March 2015, Pages: 399–414, Sandra I. Duque, W. David Arnold, Philipp Odermatt, Xiaohui Li, Paul N. Porensky, Leah Schmelzer, Kathrin Meyer, Stephen J. Kolb, Daniel Schümperli, Brian K. Kaspar and Arthur H. M. Burghes

    Version of Record online : 9 FEB 2015, DOI: 10.1002/ana.24332

  13. SMN and Gemins: ‘We are family’ … or are we?

    BioEssays

    Volume 32, Issue 12, December 2010, Pages: 1077–1089, Ruben J. Cauchi

    Version of Record online : 15 OCT 2010, DOI: 10.1002/bies.201000088

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    Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice

    British Journal of Pharmacology

    Volume 166, Issue 3, June 2012, Pages: 1114–1126, Ya-Yun Hsu, Yuh-Jyh Jong, Hsin-Hung Tsai, Yu-Ting Tseng, Li-Mei An and Yi-Ching Lo

    Version of Record online : 8 MAY 2012, DOI: 10.1111/j.1476-5381.2012.01829.x

  15. Developing therapies for spinal muscular atrophy

    Annals of the New York Academy of Sciences

    Volume 1366, Issue 1, February 2016, Pages: 5–19, Mary H. Wertz and Mustafa Sahin

    Version of Record online : 14 JUL 2015, DOI: 10.1111/nyas.12813

  16. Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells

    Annals of Neurology

    Volume 58, Issue 2, August 2005, Pages: 194–202, Susanna M. Grzeschik, Madhuri Ganta, Thomas W. Prior, William D. Heavlin and Ching H. Wang

    Version of Record online : 14 APR 2010, DOI: 10.1002/ana.20548

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    Solving the puzzle of spinal muscular atrophy: What are the missing pieces?

    American Journal of Medical Genetics Part A

    Volume 161, Issue 11, November 2013, Pages: 2836–2845, Francesco Danilo Tiziano, Judith Melki and Louise R. Simard

    Version of Record online : 3 OCT 2013, DOI: 10.1002/ajmg.a.36251

  18. SMN in spinal muscular atrophy and snRNP biogenesis

    Wiley Interdisciplinary Reviews: RNA

    Volume 2, Issue 4, July/August 2011, Pages: 546–564, Tristan H. Coady and Christian L. Lorson

    Version of Record online : 17 FEB 2011, DOI: 10.1002/wrna.76

  19. You have full text access to this OnlineOpen article
    The SMN Protein is a Key Regulator of Nuclear Architecture in Differentiating Neuroblastoma Cells

    Traffic

    Volume 10, Issue 11, November 2009, Pages: 1585–1598, Allyson K. Clelland, Nicholas P. Kinnear, Lisa Oram, Julie Burza and Judith E. Sleeman

    Version of Record online : 4 AUG 2009, DOI: 10.1111/j.1600-0854.2009.00972.x

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    In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy

    Journal of Neurochemistry

    Volume 98, Issue 1, July 2006, Pages: 193–202, Eric Hahnen, Ilker Y. Eyüpoglu, Lars Brichta, Kirsten Haastert, Christian Tränkle, Florian A. Siebzehnrübl, Markus Riessland, Irmgard Hölker, Peter Claus, Johann Romstöck, Rolf Buslei, Brunhilde Wirth and Ingmar Blümcke

    Version of Record online : 18 MAY 2006, DOI: 10.1111/j.1471-4159.2006.03868.x