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There are 15544 results for: content related to: SIRT1 and SIRT2: emerging targets in neurodegeneration

  1. Sirtuin activators and inhibitors


    Volume 38, Issue 5, September/October 2012, Pages: 349–359, José M. Villalba and Francisco J. Alcaín

    Article first published online : 25 JUN 2012, DOI: 10.1002/biof.1032

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    Function of Sirtuins in Biological Tissues

    The Anatomical Record

    Volume 292, Issue 4, April 2009, Pages: 536–543, Balaji Shoba, Zin Mar Lwin, Lo Soo Ling, Boon-Huat Bay, George W. Yip and Srinivasan Dinesh Kumar

    Article first published online : 19 MAR 2009, DOI: 10.1002/ar.20875

  3. The Role of Sirtuins in the Control of Metabolic Homeostasis

    Annals of the New York Academy of Sciences

    Volume 1173, Issue s1, September 2009, Pages: E10–E19, Jiujiu Yu and Johan Auwerx

    Article first published online : 11 SEP 2009, DOI: 10.1111/j.1749-6632.2009.04952.x

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    SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling


    Volume 57, Issue 6, June 2013, Pages: 2287–2298, Juan Chen, Anthony W.H. Chan, Ka-Fai To, Weixian Chen, Zhenzhen Zhang, Jihua Ren, Chunli Song, Yue-Sun Cheung, Paul B.S. Lai, Suk-Hang Cheng, Margaret H.L. Ng, Ailong Huang and Ben C.B. Ko

    Article first published online : 26 APR 2013, DOI: 10.1002/hep.26278

  5. NAD+-dependent histone deacetylases (sirtuins) as novel therapeutic targets

    Medicinal Research Reviews

    Volume 30, Issue 6, November 2010, Pages: 861–889, Jörg Schemies, Urszula Uciechowska, Wolfgang Sippl and Manfred Jung

    Article first published online : 12 OCT 2009, DOI: 10.1002/med.20178

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    Identification of serum sirtuins as novel noninvasive protein markers for frailty

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 975–980, Rahul Kumar, Navinath Mohan, Ashish Datt Upadhyay, Amrendra Pratap Singh, Vishal Sahu, Sadanand Dwivedi, Aparajit B. Dey and Sharmistha Dey

    Article first published online : 7 AUG 2014, DOI: 10.1111/acel.12260

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    Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

    EMBO Molecular Medicine

    Volume 4, Issue 7, July 2012, Pages: 557–560, Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, Antonello Mai, Tiago F. Outeiro and Aleksey G. Kazanstev

    Article first published online : 18 MAY 2012, DOI: 10.1002/emmm.201201452

    Corrected by:

    Corrigendum: Corrigendum

    Vol. 4, Issue 8, 840, Article first published online: 3 AUG 2012

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    Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells

    Genes to Cells

    Volume 10, Issue 4, April 2005, Pages: 321–332, Nobuko Matsushita, Yasunari Takami, Masayo Kimura, Seiji Tachiiri, Masamichi Ishiai, Takeo Nakayama and Minoru Takata

    Article first published online : 1 MAR 2005, DOI: 10.1111/j.1365-2443.2005.00836.x

  9. Mitochondrial sirtuins – a new therapeutic target for repair and protection in multiple sclerosis

    European Journal of Neuroscience

    Volume 35, Issue 12, June 2012, Pages: 1887–1893, C. M. Rice, M. Sun, K. Kemp, E. Gray, A. Wilkins and N. J. Scolding

    Article first published online : 19 JUN 2012, DOI: 10.1111/j.1460-9568.2012.08150.x

  10. Sirtuin gene expression in human mononuclear cells is modulated by caloric restriction

    European Journal of Clinical Investigation

    Volume 38, Issue 9, September 2008, Pages: 672–678, A. B. Crujeiras, D. Parra, E. Goyenechea and J. A. Martínez

    Article first published online : 18 AUG 2008, DOI: 10.1111/j.1365-2362.2008.01998.x

  11. NAD-Dependent Deacetylases as Therapeutic Targets

    Epigenetic Targets in Drug Discovery, Volume 42

    Hongzhe Li, Julian Simon, Antonio Bedalov, Pages: 225–242, 2010

    Published Online : 25 FEB 2010, DOI: 10.1002/9783527627073.ch10

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    Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity

    FEBS Journal

    Laia Bosch-Presegué and Alejandro Vaquero

    Article first published online : 13 OCT 2014, DOI: 10.1111/febs.13053

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    The Discovery of a Highly Selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model


    Volume 10, Issue 1, January 2015, Pages: 69–82, Dr. Paolo Di Fruscia, Emmanouil Zacharioudakis, Chang Liu, Dr. Sébastien Moniot, Sasiwan Laohasinnarong, Mattaka Khongkow, Ian F. Harrison, Konstantina Koltsida, Dr. Christopher R. Reynolds, Karin Schmidtkunz, Prof. Dr. Manfred Jung, Dr. Kathryn L. Chapman, Prof. Dr. Clemens Steegborn, Prof. David T. Dexter, Prof. Michael J. E. Sternberg, Prof. Eric W.-F. Lam and Dr. Matthew J. Fuchter

    Article first published online : 13 NOV 2014, DOI: 10.1002/cmdc.201402431

  14. You have full text access to this OnlineOpen article
    Janus-faced role of SIRT1 in tumorigenesis

    Annals of the New York Academy of Sciences

    Volume 1271, Issue 1, October 2012, Pages: 10–19, Na-Young Song and Young-Joon Surh

    Article first published online : 10 OCT 2012, DOI: 10.1111/j.1749-6632.2012.06762.x

  15. The FoxO Transcription Factors and Sirtuins

    Metabolic Syndrome and Cardiovascular Disease, Second Edition

    T. Barry Levine, Arlene B. Levine, Pages: 64–95, 2012

    Published Online : 6 AUG 2012, DOI: 10.1002/9781118480045.ch4

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    A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53

    EMBO Molecular Medicine

    Volume 4, Issue 4, April 2012, Pages: 298–312, Qi Zhang, Shelya X. Zeng, Yu Zhang, Yiwei Zhang, Derong Ding, Qizhuang Ye, Samy O. Meroueh and Hua Lu

    Article first published online : 13 FEB 2012, DOI: 10.1002/emmm.201100211

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    The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing

    Diabetes, Obesity and Metabolism

    Volume 15, Issue s3, September 2013, Pages: 26–33, S. Imai and J. Yoshino

    Article first published online : 4 SEP 2013, DOI: 10.1111/dom.12171

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    The promise and perils of HDAC inhibitors in neurodegeneration

    Annals of Clinical and Translational Neurology

    Volume 2, Issue 1, January 2015, Pages: 79–101, Alessandro Didonna and Puneet Opal

    Article first published online : 3 DEC 2014, DOI: 10.1002/acn3.147

  19. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus

    Journal of Neuroscience Research

    Volume 91, Issue 5, May 2013, Pages: 642–659, Sumiti Saharan, Dhanisha J. Jhaveri and Perry F. Bartlett

    Article first published online : 13 FEB 2013, DOI: 10.1002/jnr.23199

  20. SIRT1 silencing confers neuroprotection through IGF-1 pathway activation

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1754–1761, Luigi Sansone, Valentina Reali, Laura Pellegrini, Lidia Villanova, Michele Aventaggiato, Gabriella Marfe, Roberta Rosa, Marcella Nebbioso, Marco Tafani, Massimo Fini, Matteo A. Russo and Bruna Pucci

    Article first published online : 18 APR 2013, DOI: 10.1002/jcp.24334