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There are 2730 results for: content related to: Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy

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    Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 239–258, Monica Giannotta, Sara Benedetti, Francesco Saverio Tedesco, Monica Corada, Marianna Trani, Rocco D'Antuono, Queensta Millet, Fabrizio Orsenigo, Beatriz G Gálvez, Giulio Cossu and Elisabetta Dejana

    Article first published online : 30 DEC 2013, DOI: 10.1002/emmm.201302520

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    Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides

    EMBO Molecular Medicine

    Volume 8, Issue 4, April 2016, Pages: 328–345, Anthony J Hinrich, Francine M Jodelka, Jennifer L Chang, Daniella Brutman, Angela M Bruno, Clark A Briggs, Bryan D James, Grace E Stutzmann, David A Bennett, Steven A Miller, Frank Rigo, Robert A Marr and Michelle L Hastings

    Article first published online : 22 FEB 2016, DOI: 10.15252/emmm.201505846

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    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 519–538, Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg and Massimo Loda

    Article first published online : 4 FEB 2014, DOI: 10.1002/emmm.201302734

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    Corrigendum: A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

    Vol. 6, Issue 10, 1357, Article first published online: 1 SEP 2014

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    Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 259–277, Youssef Hibaoui, Iwona Grad, Audrey Letourneau, M Reza Sailani, Sophie Dahoun, Federico A Santoni, Stefania Gimelli, Michel Guipponi, Marie Françoise Pelte, Frédérique Béna, Stylianos E Antonarakis and Anis Feki

    Article first published online : 27 DEC 2013, DOI: 10.1002/emmm.201302848

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    Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

    EMBO Molecular Medicine

    Volume 7, Issue 6, June 2015, Pages: 695–713, Kevin White, Yu Lu, Sofia Annis, Andrew E Hale, B Nelson Chau, James E Dahlman, Craig Hemann, Alexander R Opotowsky, Sara O Vargas, Ivan Rosas, Mark A Perrella, Juan C Osorio, Kathleen J Haley, Brian B Graham, Rahul Kumar, Rajan Saggar, Rajeev Saggar, W Dean Wallace, David J Ross, Omar F Khan, Andrew Bader, Bernadette R Gochuico, Majed Matar, Kevin Polach, Nicolai M Johannessen, Haydn M Prosser, Daniel G Anderson, Robert Langer, Jay L Zweier, Laurence A Bindoff, David Systrom, Aaron B Waxman, Richard C Jin and Stephen Y Chan

    Article first published online : 30 MAR 2015, DOI: 10.15252/emmm.201404511

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    ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 278–294, Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M. McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch and Gail E Sonenshein

    Article first published online : 27 DEC 2013, DOI: 10.1002/emmm.201303373

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    The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

    EMBO Molecular Medicine

    Volume 7, Issue 11, November 2015, Pages: 1426–1449, Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis and Cheng Wang

    Article first published online : 28 SEP 2015, DOI: 10.15252/emmm.201404976

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    Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB

    EMBO Molecular Medicine

    Volume 6, Issue 9, September 2014, Pages: 1142–1160, Vinicia A Polito, Hongmei Li, Heidi Martini-Stoica, Baiping Wang, Li Yang, Yin Xu, Daniel B Swartzlander, Michela Palmieri, Alberto di Ronza, Virginia M-Y Lee, Marco Sardiello, Andrea Ballabio and Hui Zheng

    Article first published online : 28 JUL 2014, DOI: 10.15252/emmm.201303671

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    Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model

    EMBO Molecular Medicine

    Volume 6, Issue 3, March 2014, Pages: 398–413, Ana I Arroyo, Paola G Camoletto, Laura Morando, Marco Sassoe-Pognetto, Maurizio Giustetto, Paul P Van Veldhoven, Edward H Schuchman and Maria D Ledesma

    Article first published online : 21 JAN 2014, DOI: 10.1002/emmm.201302649

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    HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice

    EMBO Molecular Medicine

    Volume 7, Issue 1, January 2015, Pages: 78–101, Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa, Xigui Chen, Hidenori Homma, Toshikazu Sasabe, Jun Shimizu, Shigeomi Shimizu, Takuya Tamura, Shin-ichi Muramatsu and Hitoshi Okazawa

    Article first published online : 15 DEC 2014, DOI: 10.15252/emmm.201404392

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    The unfolded protein response affects readthrough of premature termination codons

    EMBO Molecular Medicine

    Volume 6, Issue 5, May 2014, Pages: 685–701, Yifat S Oren, Michelle L McClure, Steven M Rowe, Eric J Sorscher, Assaf C Bester, Miriam Manor, Eitan Kerem, Joseph Rivlin, Fouad Zahdeh, Matthias Mann, Tamar Geiger and Batsheva Kerem

    Article first published online : 4 APR 2014, DOI: 10.1002/emmm.201303347

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    Effective delivery of large genes to the retina by dual AAV vectors

    EMBO Molecular Medicine

    Volume 6, Issue 2, February 2014, Pages: 194–211, Ivana Trapani, Pasqualina Colella, Andrea Sommella, Carolina Iodice, Giulia Cesi, Sonia de Simone, Elena Marrocco, Settimio Rossi, Massimo Giunti, Arpad Palfi, Gwyneth J Farrar, Roman Polishchuk and Alberto Auricchio

    Article first published online : 16 DEC 2013, DOI: 10.1002/emmm.201302948

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    Monocyte-derived dendritic cells promote T follicular helper cell differentiation

    EMBO Molecular Medicine

    Volume 6, Issue 5, May 2014, Pages: 590–603, Svetoslav Chakarov and Nicolas Fazilleau

    Article first published online : 11 APR 2014, DOI: 10.1002/emmm.201403841

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    FGF23 regulates renal sodium handling and blood pressure

    EMBO Molecular Medicine

    Volume 6, Issue 6, June 2014, Pages: 744–759, Olena Andrukhova, Svetlana Slavic, Alina Smorodchenko, Ute Zeitz, Victoria Shalhoub, Beate Lanske, Elena E Pohl and Reinhold G Erben

    Article first published online : 5 MAY 2014, DOI: 10.1002/emmm.201303716

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    Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

    EMBO Molecular Medicine

    Volume 6, Issue 4, April 2014, Pages: 467–481, Stacey J Coleman, Athina-Myrto Chioni, Mohammed Ghallab, Rhys K Anderson, Nicholas R Lemoine, Hemant M Kocher and Richard P Grose

    Article first published online : 6 FEB 2014, DOI: 10.1002/emmm.201302698

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    Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis

    EMBO Molecular Medicine

    Volume 6, Issue 1, January 2014, Pages: 27–42, Jesmond Dalli, Lucy V Norling, Trinidad Montero-Melendez, Donata Federici Canova, Hazem Lashin, Anton M Pavlov, Gleb B Sukhorukov, Charles J Hinds and Mauro Perretti

    Article first published online : 16 DEC 2013, DOI: 10.1002/emmm.201303503

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    Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis

    EMBO Molecular Medicine

    Volume 7, Issue 10, October 2015, Pages: 1267–1284, Wan-Jen Yang, Junhao Hu, Akiyoshi Uemura, Fabian Tetzlaff, Hellmut G Augustin and Andreas Fischer

    Article first published online : 20 JUL 2015, DOI: 10.15252/emmm.201404922

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    A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases

    EMBO Molecular Medicine

    Jakob Körbelin, Godwin Dogbevia, Stefan Michelfelder, Dirk A Ridder, Agnes Hunger, Jan Wenzel, Henning Seismann, Melanie Lampe, Jacqueline Bannach, Manolis Pasparakis, Jürgen A Kleinschmidt, Markus Schwaninger and Martin Trepel

    Article first published online : 22 APR 2016, DOI: 10.15252/emmm.201506078

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    Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 339–356, Agnes Lau, Alex McDonald, Nathalie Daude, Charles E Mays, Eric D Walter, Robin Aglietti, Robert CC Mercer, Serene Wohlgemuth, Jacques van der Merwe, Jing Yang, Hristina Gapeshina, Chae Kim, Jennifer Grams, Beipei Shi, Holger Wille, Aru Balachandran, Gerold Schmitt-Ulms, Jiri G Safar, Glenn L Millhauser and David Westaway

    Article first published online : 6 FEB 2015, DOI: 10.15252/emmm.201404588

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    Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

    EMBO Molecular Medicine

    Volume 8, Issue 2, February 2016, Pages: 105–116, Ewelina Testoni, Natalie L Stephenson, Pedro Torres-Ayuso, Anna A Marusiak, Eleanor W Trotter, Andrew Hudson, Cassandra L Hodgkinson, Christopher J Morrow, Caroline Dive and John Brognard

    Article first published online : 12 JAN 2016, DOI: 10.15252/emmm.201505456