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There are 14688 results for: content related to: Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies

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    Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1502–1522, Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El-Ashry and Joyce M. Slingerland

    Version of Record online : 27 AUG 2013, DOI: 10.1002/emmm.201302558

  2. You have full text access to this OnlineOpen article
    CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1775–1793, Florian Sennlaub, Constance Auvynet, Bertrand Calippe, Sophie Lavalette, Lucie Poupel, Shulong J. Hu, Elisa Dominguez, Serge Camelo, Olivier Levy, Elodie Guyon, Noah Saederup, Israel F. Charo, Nico Van Rooijen, Emeline Nandrot, Jean-Louis Bourges, Francine Behar-Cohen, José-Alain Sahel, Xavier Guillonneau, William Raoul and Christophe Combadiere

    Version of Record online : 21 OCT 2013, DOI: 10.1002/emmm.201302692

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    Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1720–1739, Jeong-Hwan Yoon, Su Myung Jung, Seok Hee Park, Mitsuyasu Kato, Tadashi Yamashita, In-Kyu Lee, Katsuko Sudo, Susumu Nakae, Jin Soo Han, Ok-Hee Kim, Byung-Chul Oh, Takayuki Sumida, Masahiko Kuroda, Ji-Hyeon Ju, Kyeong Cheon Jung, Seong Hoe Park, Dae-Kee Kim and Mizuko Mamura

    Version of Record online : 11 OCT 2013, DOI: 10.1002/emmm.201302524

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    Antimicrobial peptides and gut microbiota in homeostasis and pathology

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1465–1483, Maureen J. Ostaff, Eduard Friedrich Stange and Jan Wehkamp

    Version of Record online : 23 AUG 2013, DOI: 10.1002/emmm.201201773

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    Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II

    EMBO Molecular Medicine

    Volume 5, Issue 12, December 2013, Pages: 1871–1886, Katrin Kollmann, Jan Malte Pestka, Sonja Christin Kühn, Elisabeth Schöne, Michaela Schweizer, Kathrin Karkmann, Takanobu Otomo, Philip Catala-Lehnen, Antonio Virgilio Failla, Robert Percy Marshall, Matthias Krause, Rene Santer, Michael Amling, Thomas Braulke and Thorsten Schinke

    Version of Record online : 15 OCT 2013, DOI: 10.1002/emmm.201302979

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    The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1523–1536, Rossella Lucá, Michele Averna, Francesca Zalfa, Manuela Vecchi, Fabrizio Bianchi, Giorgio La Fata, Franca Del Nonno, Roberta Nardacci, Marco Bianchi, Paolo Nuciforo, Sebastian Munck, Paola Parrella, Rute Moura, Emanuela Signori, Robert Alston, Anna Kuchnio, Maria Giulia Farace, Vito Michele Fazio, Mauro Piacentini, Bart De Strooper, Tilmann Achsel, Giovanni Neri, Patrick Neven, D. Gareth Evans, Peter Carmeliet, Massimiliano Mazzone and Claudia Bagni

    Version of Record online : 16 SEP 2013, DOI: 10.1002/emmm.201302847

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    Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination

    EMBO Molecular Medicine

    Volume 5, Issue 12, December 2013, Pages: 1918–1934, Yasir A. Syed, Alexandra Baer, Matthias P. Hofer, Ginez A. González, Jon Rundle, Szymon Myrta, Jeffrey K. Huang, Chao Zhao, Moritz J. Rossner, Matthew W. B. Trotter, Gert Lubec, Robin J. M. Franklin and Mark R. Kotter

    Version of Record online : 21 OCT 2013, DOI: 10.1002/emmm.201303123

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    A major role for RCAN1 in atherosclerosis progression

    EMBO Molecular Medicine

    Volume 5, Issue 12, December 2013, Pages: 1901–1917, Nerea Méndez-Barbero, Vanesa Esteban, Silvia Villahoz, Amelia Escolano, Katia Urso, Arantzazu Alfranca, Cristina Rodríguez, Susana A. Sánchez, Tsuyoshi Osawa, Vicente Andrés, José Martínez-González, Takashi Minami, Juan Miguel Redondo and Miguel R. Campanero

    Version of Record online : 15 OCT 2013, DOI: 10.1002/emmm.201302842

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    Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1759–1774, Lorena Pereira, Ana Igea, Begoña Canovas, Ignacio Dolado and Angel R. Nebreda

    Version of Record online : 24 SEP 2013, DOI: 10.1002/emmm.201302732

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    An essential role for decorin in bladder cancer invasiveness

    EMBO Molecular Medicine

    Volume 5, Issue 12, December 2013, Pages: 1835–1851, Mohamed El Behi, Sophie Krumeich, Catalina Lodillinsky, Aurélie Kamoun, Lorenzo Tibaldi, Gaël Sugano, Aurélien De Reynies, Elodie Chapeaublanc, Agnès Laplanche, Thierry Lebret, Yves Allory, François Radvanyi, Olivier Lantz, Ana María Eiján, Isabelle Bernard-Pierrot and Clotilde Théry

    Version of Record online : 20 OCT 2013, DOI: 10.1002/emmm.201302655

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    Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1484–1501, Norbert Odolczyk, Janine Fritsch, Caroline Norez, Nathalie Servel, Melanie Faria da Cunha, Sara Bitam, Anna Kupniewska, Ludovic Wiszniewski, Julien Colas, Krzysztof Tarnowski, Danielle Tondelier, Ariel Roldan, Emilie L. Saussereau, Patricia Melin-Heschel, Grzegorz Wieczorek, Gergely L. Lukacs, Michal Dadlez, Grazyna Faure, Harald Herrmann, Mario Ollero, Frédéric Becq, Piotr Zielenkiewicz and Aleksander Edelman

    Version of Record online : 27 AUG 2013, DOI: 10.1002/emmm.201302699

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    Pathological impact of SMN2 mis-splicing in adult SMA mice

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1586–1601, Kentaro Sahashi, Karen K. Y. Ling, Yimin Hua, John Erby Wilkinson, Tomoki Nomakuchi, Frank Rigo, Gene Hung, David Xu, Ya-Ping Jiang, Richard Z. Lin, Chien-Ping Ko, C. Frank Bennett and Adrian R. Krainer

    Version of Record online : 9 SEP 2013, DOI: 10.1002/emmm.201302567

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    Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

    EMBO Molecular Medicine

    Volume 5, Issue 7, July 2013, Pages: 1000–1016, Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Filip Van Hauwermeiren, Sofie Lodens, Riet De Rycke, Elien Van Wonterghem, An Staes, Kris Gevaert, Carlos López-Otin and Claude Libert

    Version of Record online : 30 MAY 2013, DOI: 10.1002/emmm.201202100

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    Gene therapy on the move

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1642–1661, Kerstin B. Kaufmann, Hildegard Büning, Anne Galy, Axel Schambach and Manuel Grez

    Version of Record online : 17 SEP 2013, DOI: 10.1002/emmm.201202287

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    Role of stress-inducible protein-1 in recruitment of bone marrow derived cells into the ischemic brains

    EMBO Molecular Medicine

    Volume 5, Issue 8, August 2013, Pages: 1227–1246, Shin-Da Lee, Ted Weita Lai, Shinn-Zong Lin, Chen-Huan Lin, Yung-Hsiang Hsu, Chi-Yuan Li, Hsiao-Jung Wang, Wei Lee, Ching-Yuan Su, Yung-Luen Yu and Woei-Cherng Shyu

    Version of Record online : 8 JUL 2013, DOI: 10.1002/emmm.201202258

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    Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance

    EMBO Molecular Medicine

    Volume 5, Issue 8, August 2013, Pages: 1247–1262, Irina Lonskaya, Michaeline L. Hebron, Nicole M. Desforges, Alexander Franjie and Charbel E.-H. Moussa

    Version of Record online : 4 JUL 2013, DOI: 10.1002/emmm.201302771

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    The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

    EMBO Molecular Medicine

    Volume 5, Issue 8, August 2013, Pages: 1196–1212, Florian A. Siebzehnrubl, Daniel J. Silver, Bugra Tugertimur, Loic P. Deleyrolle, Dorit Siebzehnrubl, Matthew R. Sarkisian, Kelly G. Devers, Antony T. Yachnis, Marius D. Kupper, Daniel Neal, Nancy H. Nabilsi, Michael P. Kladde, Oleg Suslov, Simone Brabletz, Thomas Brabletz, Brent A. Reynolds and Dennis A. Steindler

    Version of Record online : 1 JUL 2013, DOI: 10.1002/emmm.201302827

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    VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

    EMBO Molecular Medicine

    Volume 5, Issue 10, October 2013, Pages: 1569–1585, Christopher R. Heier, Jesse M. Damsker, Qing Yu, Blythe C. Dillingham, Tony Huynh, Jack H. Van der Meulen, Arpana Sali, Brittany K. Miller, Aditi Phadke, Luana Scheffer, James Quinn, Kathleen Tatem, Sarah Jordan, Sherry Dadgar, Olga C. Rodriguez, Chris Albanese, Michael Calhoun, Heather Gordish-Dressman, Jyoti K. Jaiswal, Edward M. Connor, John M. McCall, Eric P. Hoffman, Erica K. M. Reeves and Kanneboyina Nagaraju

    Version of Record online : 9 SEP 2013, DOI: 10.1002/emmm.201302621

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    Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model

    EMBO Molecular Medicine

    Volume 5, Issue 12, December 2013, Pages: 1804–1820, Nina Cabezas-Wallscheid, Victoria Eichwald, Jos de Graaf, Martin Löwer, Hans-Anton Lehr, Andreas Kreft, Leonid Eshkind, Andreas Hildebrandt, Yasmin Abassi, Rosario Heck, Anna Katharina Dehof, Svetlana Ohngemach, Rolf Sprengel, Simone Wörtge, Steffen Schmitt, Johannes Lotz, Claudius Meyer, Thomas Kindler, Dong-Er Zhang, Bernd Kaina, John C. Castle, Andreas Trumpp, Ugur Sahin and Ernesto Bockamp

    Version of Record online : 4 OCT 2013, DOI: 10.1002/emmm.201302661

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    Genome-wide identification and functional analyses of microRNA signatures associated with cancer pain

    EMBO Molecular Medicine

    Volume 5, Issue 11, November 2013, Pages: 1740–1758, Kiran Kumar Bali, Deepitha Selvaraj, Venkata P. Satagopam, Jianning Lu, Reinhard Schneider and Rohini Kuner

    Version of Record online : 18 OCT 2013, DOI: 10.1002/emmm.201302797