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There are 6649 results for: content related to: Occurrence, fate, and persistence of gemfibrozil in water and soil

  1. Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas)

    Environmental Toxicology and Chemistry

    Volume 31, Issue 11, November 2012, Pages: 2615–2624, Sarah Y. Skolness, Elizabeth J. Durhan, Kathleen M. Jensen, Michael D. Kahl, Elizabeth A. Makynen, Daniel L. Villeneuve and Gerald T. Ankley

    Article first published online : 19 SEP 2012, DOI: 10.1002/etc.1989

  2. You have free access to this content
    The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies

    British Journal of Pharmacology

    Volume 172, Issue 9, May 2015, Pages: 2316–2329, I G Sharina, M Sobolevsky, A Papakyriakou, N Rukoyatkina, G A Spyroulias, S Gambaryan and E Martin

    Article first published online : 10 FEB 2015, DOI: 10.1111/bph.13055

  3. Gemfibrozil Is a Strong Inactivator of CYP2C8 in Very Small Multiple Doses

    Clinical Pharmacology & Therapeutics

    Volume 91, Issue 5, May 2012, Pages: 846–855, J Honkalammi, M Niemi, P J Neuvonen and J T Backman

    Article first published online : 4 APR 2012, DOI: 10.1038/clpt.2011.313

  4. Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers

    The Journal of Clinical Pharmacology

    Volume 50, Issue 9, September 2010, Pages: 1039–1049, Dr Ebba Bergman, Mrs Elin M. Matsson, Dr Mikael Hedeland, Dr Ulf Bondesson, Dr Lars Knutson and Dr Hans Lennernäs

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009357432

  5. Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib

    The Journal of Clinical Pharmacology

    Volume 55, Issue 4, April 2015, Pages: 392–400, A. Benjamin Suttle, Kenneth F. Grossmann, Daniele Ouellet, Lauren E. Richards-Peterson, Gursel Aktan, Michael S. Gordon, Patricia M. LoRusso, Jeffrey R. Infante, Sunil Sharma, Kari Kendra, Manish Patel, Shubham Pant, Hendrik-Tobias Arkenau, Mark R. Middleton, Samuel C. Blackman, Jeff Botbyl and Stanley W. Carson

    Article first published online : 30 DEC 2014, DOI: 10.1002/jcph.437

  6. The Effect of Gemfibrozil on Repaglinide Pharmacokinetics Persists for at Least 12 h After the Dose: Evidence for Mechanism-based Inhibition of CYP2C8 In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 84, Issue 3, September 2008, Pages: 403–411, A Tornio, M Niemi, M Neuvonen, J Laitila, A Kalliokoski, PJ Neuvonen and JT Backman

    Article first published online : 26 MAR 2008, DOI: 10.1038/clpt.2008.34

  7. Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans

    Clinical Pharmacology & Therapeutics

    Volume 89, Issue 4, April 2011, Pages: 579–586, J Honkalammi, M Niemi, PJ Neuvonen and JT Backman

    Article first published online : 2 MAR 2011, DOI: 10.1038/clpt.2010.358

  8. Effect of Gemfibrozil and Fenofibrate on the Pharmacokinetics of Atorvastatin

    The Journal of Clinical Pharmacology

    Volume 51, Issue 3, March 2011, Pages: 378–388, Dr Lloyd R. Whitfield, Dr Anthony R. Porcari, Ms Christine Alvey, Dr Robert Abel, Mr William Bullen and Dr Daniel Hartman

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010366446

  9. Effects of Gemfibrozil, Itraconazole, and Their Combination on the Pharmacokinetics of Pioglitazone

    Clinical Pharmacology & Therapeutics

    Volume 77, Issue 5, May 2005, Pages: 404–414, Tiina Jaakkola, Janne T. Backman, Mikko Neuvonen and Pertti J. Neuvonen

    Article first published online : 16 MAY 2005, DOI: 10.1016/j.clpt.2004.12.266

  10. The Helsinki Heart Study: an 8.5-year safety and mortality follow-up

    Journal of Internal Medicine

    Volume 235, Issue 1, January 1994, Pages: 31–39, Professor Jussi K. Huttunen, O. P. Heinonen, V. Manninen, P. Koskinen, T. Hakulinen, L. Teppo, M. Mänttäri and M. H. Frick

    Article first published online : 3 AUG 2009, DOI: 10.1111/j.1365-2796.1994.tb01029.x

  11. The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

    Clinical Pharmacology & Therapeutics

    Volume 75, Issue 5, May 2004, Pages: 455–463, Dennis W. Schneck, Bruce K. Birmingham, Julie A. Zalikowski, Patrick D. Mitchell, Yi Wang, Paul D. Martin, Kenneth C. Lasseter, Colin D. A. Brown, Amy S. Windass and Ali Raza

    Article first published online : 6 MAY 2004, DOI: 10.1016/j.clpt.2003.12.014

  12. Effect of gemfibrozil on peripheral atherosclerosis and platelet activation in a pig model of hyperlipidemia

    European Journal of Clinical Investigation

    Volume 30, Issue 10, October 2000, Pages: 843–852, T. Royo, J. Alfón, M. Berrozpe and L. Badimon

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1365-2362.2000.00711.x

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    Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide

    British Journal of Clinical Pharmacology

    Volume 60, Issue 2, August 2005, Pages: 208–217, Mikko Niemi, Janne T. Backman, Laura Juntti-Patinen, Mikko Neuvonen and Pertti J. Neuvonen

    Article first published online : 30 MAR 2005, DOI: 10.1111/j.1365-2125.2005.02385.x

  14. You have free access to this content
    Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism

    British Journal of Clinical Pharmacology

    Volume 70, Issue 6, December 2010, Pages: 870–880, Jinping Gan, Weiqi Chen, Hong Shen, Ling Gao, Yang Hong, Yuan Tian, Wenying Li, Yueping Zhang, Yuwei Tang, Hongjian Zhang, William Griffith Humphreys and A. David Rodrigues

    Article first published online : 11 NOV 2010, DOI: 10.1111/j.1365-2125.2010.03772.x

  15. Gemfibrozil Markedly Increases the Plasma Concentrations of Montelukast: A Previously Unrecognized Role for CYP2C8 in the Metabolism of Montelukast

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 2, August 2010, Pages: 223–230, T Karonen, A Filppula, J Laitila, M Niemi, P J Neuvonen and J T Backman

    Article first published online : 30 JUN 2010, DOI: 10.1038/clpt.2010.73

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    Impact of the CYP2C8 *3 polymorphism on the drug–drug interaction between gemfibrozil and pioglitazone

    British Journal of Clinical Pharmacology

    Volume 75, Issue 1, January 2013, Pages: 217–226, Christina L. Aquilante, Lisa A. Kosmiski, David W. A. Bourne, Lane R. Bushman, Elizabeth B. Daily, Kyle P. Hammond, Charles W. Hopley, Rajendra S. Kadam, Alexander T. Kanack, Uday B. Kompella, Merry Le, Julie A. Predhomme, Joseph E. Rower and Maha S. Sidhom

    Article first published online : 14 DEC 2012, DOI: 10.1111/j.1365-2125.2012.04343.x

  17. Gemfibrozil Impairs Imatinib Absorption and Inhibits the CYP2C8-Mediated Formation of Its Main Metabolite

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 3, September 2013, Pages: 383–393, A M Filppula, A Tornio, M Niemi, P J Neuvonen and J T Backman

    Article first published online : 8 MAY 2013, DOI: 10.1038/clpt.2013.92

  18. Study on the Supramolecular Interaction of β-Cyclodextrin with Gemfibrozil by Spectrofluorimetry and Its Analytical Application

    Chinese Journal of Chemistry

    Volume 25, Issue 3, March, 2007, Pages: 337–342, Hui Huang, Fang Liu, Bao-Xiu Jia, Ke-Hua Xu, Zhen-Zhen Chen and Bo Tang

    Article first published online : 5 MAR 2007, DOI: 10.1002/cjoc.200790065

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    Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 59, Issue 4, April 2005, Pages: 433–439, Jari J. Lilja, Janne T. Backman and Pertti J. Neuvonen

    Article first published online : 22 DEC 2004, DOI: 10.1111/j.1365-2125.2004.02323.x

  20. Apparent Reduced Absorption of Gemfibrozil When Given with Colestipol

    The Journal of Clinical Pharmacology

    Volume 30, Issue 1, January 1990, Pages: 29–32, S. C. Forland, Y. Feng and R. E. Cutler

    Article first published online : 8 MAR 2013, DOI: 10.1002/j.1552-4604.1990.tb03434.x