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There are 22849 results for: content related to: Germline copy number variations in BRCA1 -associated ovarian cancer patients

  1. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2

    Human Mutation

    Volume 33, Issue 6, June 2012, Pages: 998–1009, Kevin Cheeseman, Etienne Rouleau, Anne Vannier, Aurélie Thomas, Adrien Briaux, Cedrick Lefol, Pierre Walrafen, Aaron Bensimon, Rosette Lidereau, Emmanuel Conseiller and Maurizio Ceppi

    Version of Record online : 4 APR 2012, DOI: 10.1002/humu.22060

  2. You have full text access to this OnlineOpen article
    Novel BRCA1 and BRCA2 Tumor Test as Basis for Treatment Decisions and Referral for Genetic Counselling of Patients with Ovarian Carcinomas

    Human Mutation

    Volume 38, Issue 2, February 2017, Pages: 226–235, Robbert D.A. Weren, Arjen R. Mensenkamp, Michiel Simons, Astrid Eijkelenboom, Aisha S. Sie, Hicham Ouchene, Monique van Asseldonk, Encarna B. Gomez-Garcia, Marinus J. Blok, Joanne A. de Hullu, Marcel R. Nelen, Alexander Hoischen, Johan Bulten, Bastiaan B.J. Tops, Nicoline Hoogerbrugge and Marjolijn J.L. Ligtenberg

    Version of Record online : 9 NOV 2016, DOI: 10.1002/humu.23137

  3. You have free access to this content
    ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

    The EMBO Journal

    Volume 25, Issue 10, May 17, 2006, Pages: 2167–2177, Liu Cao, Sangsoo Kim, Cuiying Xiao, Rui-Hong Wang, Xavier Coumoul, Xiaoyan Wang, Wen Mei Li, Xiao Ling Xu, Joseph A De Soto, Hiroyuki Takai, Sabine Mai, Stephen J Elledge, Noboru Motoyama and Chu-Xia Deng

    Version of Record online : 4 MAY 2006, DOI: 10.1038/sj.emboj.7601115

  4. Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

    Human Mutation

    Volume 33, Issue 12, December 2012, Pages: 1665–1675, Brooke L. Brewster, Francesca Rossiello, Juliet D. French, Stacey L. Edwards, Ming Wong, Ania Wronski, Phillip Whiley, Nic Waddell, Xiaowei Chen, Betsy Bove, kConFab, John L. Hopper, Esther M. John, Irene Andrulis, Mary Daly, Sara Volorio, Loris Bernard, Bernard Peissel, Siranoush Manoukian, Monica Barile, Sara Pizzamiglio, Paolo Verderio, Amanda B. Spurdle, Paolo Radice, Andrew K. Godwin, Melissa C Southey, Melissa A. Brown and Paolo Peterlongo

    Version of Record online : 2 AUG 2012, DOI: 10.1002/humu.22159

  5. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

    The Journal of Pathology

    Volume 227, Issue 1, May 2012, Pages: 29–41, Rachael Natrajan, Alan Mackay, Maryou B Lambros, Britta Weigelt, Paul M Wilkerson, Elodie Manie, Anita Grigoriadis, Roger A'Hern, Petra van der Groep, Iwanka Kozarewa, Tatiana Popova, Odette Mariani, Samra Turajlic, Simon J Furney, Richard Marais, Daniel-Nava Rodruigues, Adriana C Flora, Patty Wai, Vidya Pawar, Simon McDade, Jason Carroll, Dominique Stoppa-Lyonnet, Andrew R Green, Ian O Ellis, Charles Swanton, Paul van Diest, Olivier Delattre, Christopher J Lord, William D Foulkes, Anne Vincent-Salomon, Alan Ashworth, Marc Henri Stern and Jorge S Reis-Filho

    Version of Record online : 23 FEB 2012, DOI: 10.1002/path.4003

  6. BRCA1-2 diagnostic workflow from next-generation sequencing technologies to variant identification and final report

    Genes, Chromosomes and Cancer

    Volume 55, Issue 10, October 2016, Pages: 803–813, Brunella Pilato, Rosamaria Pinto, Simona De Summa, Daniela Petriella, Rosanna Lacalamita, Katia Danza, Angelo Paradiso and Stefania Tommasi

    Version of Record online : 4 JUL 2016, DOI: 10.1002/gcc.22383

  7. You have full text access to this Open Access content
    The Contribution of BRCA1 and BRCA2 to Ovarian Cancer

    Molecular Oncology

    Volume 3, Issue 2, April 2009, Pages: 138–150, Susan J. Ramus, Simon A. Gayther

    Version of Record online : 10 FEB 2009, DOI: 10.1016/j.molonc.2009.02.001

  8. You have full text access to this Open Access content
    Proper genomic profiling of (BRCA1-mutated) basal-like breast carcinomas requires prior removal of tumor infiltrating lymphocytes

    Molecular Oncology

    Volume 9, Issue 4, April 2015, Pages: 877–888, Maarten P.G. Massink, Irsan E. Kooi, Saskia E. van Mil, Ekaterina S. Jordanova, Najim Ameziane, Josephine C. Dorsman, Daphne M. van Beek, J. Patrick van der Voorn, Daoud Sie, Bauke Ylstra, Carolien H.M. van Deurzen, John W. Martens, Marcel Smid, Anieta M. Sieuwerts, Vanja de Weerd, John A. Foekens, Ans M.W. van den Ouweland, Ewald van Dyk, Petra M. Nederlof, Quinten Waisfisz, Hanne Meijers-Heijboer

    Version of Record online : 13 JAN 2015, DOI: 10.1016/j.molonc.2014.12.012

  9. BRCA1 alterations with additional defects in DNA damage response genes may confer chemoresistance to BRCA-like breast cancers treated with neoadjuvant chemotherapy

    Genes, Chromosomes and Cancer

    Volume 56, Issue 5, May 2017, Pages: 405–420, Mamoru Takada, Shigenori Nagai, Masayuki Haruta, Ryuichi P. Sugino, Katsunori Tozuka, Hiroyuki Takei, Fumie Ohkubo, Kenichi Inoue, Masafumi Kurosumi, Masaru Miyazaki, Aiko Sato-Otsubo, Yusuke Sato, Seishi Ogawa and Yasuhiko Kaneko

    Version of Record online : 7 MAR 2017, DOI: 10.1002/gcc.22445

  10. Genomic alterations as mediators of miRNA dysregulation in ovarian cancer

    Genes, Chromosomes and Cancer

    Volume 54, Issue 1, January 2015, Pages: 1–19, Casina W. S. Kan, Viive M. Howell, Michael A. Hahn and Deborah J. Marsh

    Version of Record online : 3 OCT 2014, DOI: 10.1002/gcc.22221

  11. BRCA1-Mediated Inflammation and Growth Activated & Inhibited Transition Mechanisms Between No-Tumor Hepatitis/Cirrhotic Tissues and HCC

    Journal of Cellular Biochemistry

    Volume 115, Issue 4, April 2014, Pages: 641–650, Haizhen Diao, Lin Wang, Juxiang Huang, Minghu Jiang, Huilei Zhou, Xiaohe Li, Qingchun Chen, Zhenfu Jiang and Haitao Feng

    Version of Record online : 23 JAN 2014, DOI: 10.1002/jcb.24699

  12. You have full text access to this OnlineOpen article
    Gene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication

    Clinical Genetics

    L.M. Pelttari, H. Shimelis, H. Toiminen, A. Kvist, T. Törngren, Å. Borg, C. Blomqvist, R. Bützow, F. Couch, K. Aittomäki and H. Nevanlinna

    Version of Record online : 12 JAN 2018, DOI: 10.1111/cge.13123

  13. BRCA1, a Potential Predictive Biomarker in the Treatment of Breast Cancer

    The Oncologist

    Volume 12, Issue 2, February 2007, Pages: 142–150, Colin R. James, Jennifer E. Quinn, Paul B. Mullan, Patrick G. Johnston and D. Paul Harkin

    Version of Record online : 1 FEB 2007, DOI: 10.1634/theoncologist.12-2-142

  14. Genomic alterations in histopathologically normal breast tissue from BRCA1 mutation carriers may be caused by BRCA1 haploinsufficiency

    Genes, Chromosomes and Cancer

    Volume 49, Issue 1, January 2010, Pages: 78–90, Karin Rennstam, Anita Ringberg, Heather E. Cunliffe, Håkan Olsson, Göran Landberg and Ingrid Hedenfalk

    Version of Record online : 16 OCT 2009, DOI: 10.1002/gcc.20723

  15. PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer

    The Journal of Pathology

    Volume 224, Issue 4, August 2011, Pages: 564–574, Ian Paul, Kienan I Savage, Jaine K Blayney, Elisabeth Lamers, Kathy Gately, Keith Kerr, Michael Sheaff, Kenneth Arthur, Derek J Richard, Peter W Hamilton, Jacqueline A James, Kenneth J O'Byrne, D Paul Harkin, Jennifer E Quinn and Dean A Fennell

    Version of Record online : 27 JUN 2011, DOI: 10.1002/path.2925

  16. Multiple copies of mutant BRCA1 and BRCA2 alleles in breast tumors from germ-line mutation carriers

    Genes, Chromosomes and Cancer

    Volume 28, Issue 4, August 2000, Pages: 432–442, Synnöve Staff, Nina N. Nupponen, Åke Borg, Jorma J. Isola and Minna M. Tanner

    Version of Record online : 14 JUN 2000, DOI: 10.1002/1098-2264(200008)28:4<432::AID-GCC9>3.0.CO;2-J

  17. Identification of BRCA1-deficient ovarian cancers

    Acta Obstetricia et Gynecologica Scandinavica

    Volume 90, Issue 6, June 2011, Pages: 593–599, ANNE-BINE SKYTTE, MARIANNE WALDSTRØM, ANDERS AAMANN RASMUSSEN, DORTHE CRÜGER, EMMA R. WOODWARD and STEEN KØLVRAA

    Version of Record online : 15 APR 2011, DOI: 10.1111/j.1600-0412.2011.01121.x

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    The molecular pathogenesis of hereditary ovarian carcinoma

    Cancer

    Volume 116, Issue 22, 15 November 2010, Pages: 5261–5271, Barbara M. Norquist, Rochelle L. Garcia, Kimberly H. Allison, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi, Bethany J. Barrow, Barbara A. Goff and Elizabeth M. Swisher

    Version of Record online : 3 NOV 2010, DOI: 10.1002/cncr.25439

  19. Insights into the targeted elimination of BRCA1-defective cancer stem cells

    Medicinal Research Reviews

    Volume 32, Issue 5, September 2012, Pages: 948–967, Veena Somasundaram and Priya Srinivas

    Version of Record online : 2 SEP 2010, DOI: 10.1002/med.20229

  20. You have free access to this content
    BRCA1-like profile predicts benefit of tandem high dose epirubicin-cyclophospamide-thiotepa in high risk breast cancer patients randomized in the WSG-AM01 trial

    International Journal of Cancer

    Volume 139, Issue 4, 15 August 2016, Pages: 882–889, Philip C. Schouten, Oleg Gluz, Nadia Harbeck, Svjetlana Mohrmann, Raihana Diallo-Danebrock, Enrico Pelz, Janneke Kruizinga, Arno Velds, Marja Nieuwland, Ron M. Kerkhoven, Cornelia Liedtke, Markus Frick, Ronald Kates, Sabine C. Linn, Ulrike Nitz and Frederik Marme

    Version of Record online : 5 MAY 2016, DOI: 10.1002/ijc.30078