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There are 329035 results for: content related to: Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies

  1. Two-Stage Designs for Gene–Disease Association Studies with Sample Size Constraints

    Biometrics

    Volume 60, Issue 3, September 2004, Pages: 589–597, Jaya M. Satagopan, E. S. Venkatraman and Colin B. Begg

    Version of Record online : 27 AUG 2004, DOI: 10.1111/j.0006-341X.2004.00207.x

  2. Perspectives on genome-wide multi-stage family-based association studies

    Statistics in Medicine

    Volume 30, Issue 18, 15 August 2011, Pages: 2201–2221, K. Van Steen

    Version of Record online : 17 MAY 2011, DOI: 10.1002/sim.4259

  3. Simple Sequential Boundaries for Treatment Selection in Multi-Armed Randomized Clinical Trials with a Control

    Biometrics

    Volume 64, Issue 3, September 2008, Pages: 940–949, Ying Kuen Cheung

    Version of Record online : 26 OCT 2007, DOI: 10.1111/j.1541-0420.2007.00929.x

  4. Two-Phase Designs to Follow-Up Genome-Wide Association Signals With DNA Resequencing Studies

    Genetic Epidemiology

    Volume 37, Issue 3, April 2013, Pages: 229–238, Daniel J. Schaid, Gregory D. Jenkins, James N. Ingle and Richard M. Weinshilboum

    Version of Record online : 24 JAN 2013, DOI: 10.1002/gepi.21708

  5. Optimization of Two-Stage Genetic Designs Where Data Are Combined Using an Accurate and Efficient Approximation for Pearson's Statistic

    Biometrics

    Volume 62, Issue 4, December 2006, Pages: 1132–1137, József Bukszár and Edwin J. C. G. van den Oord

    Version of Record online : 2 JUN 2006, DOI: 10.1111/j.1541-0420.2006.00583.x

  6. Two-stage design for dose-finding that accounts for both efficacy and safety

    Statistics in Medicine

    Volume 27, Issue 25, 10 November 2008, Pages: 5156–5176, Vladimir Dragalin, Valerii V. Fedorov and Yuehui Wu

    Version of Record online : 4 AUG 2008, DOI: 10.1002/sim.3356

  7. Randomized phase II trials with a prospective control

    Statistics in Medicine

    Volume 27, Issue 4, 20 February 2008, Pages: 568–583, Sin-Ho Jung

    Version of Record online : 15 JUN 2007, DOI: 10.1002/sim.2961

  8. Rare genetic variants and treatment response: sample size and analysis issues

    Statistics in Medicine

    Volume 31, Issue 25, 10 November 2012, Pages: 3041–3050, John S. Witte

    Version of Record online : 27 JUN 2012, DOI: 10.1002/sim.5428

  9. Two-stage designs for Phase 2 dose-finding trials

    Statistics in Medicine

    Volume 31, Issue 24, 30 October 2012, Pages: 2872–2881, Anastasia Ivanova, Changfu Xiao and Yevgen Tymofyeyev

    Version of Record online : 1 AUG 2012, DOI: 10.1002/sim.5365

  10. Endogenous Adaptation: The Effects of Technology Position and Planning Mode on IT-Enabled Change

    Decision Sciences

    Volume 37, Issue 3, August 2006, Pages: 325–355, Victoria L. Mitchell and Robert W. Zmud

    Version of Record online : 9 OCT 2006, DOI: 10.1111/j.1540-5414.2006.00130.x

  11. Curtailed two-stage designs with two dependent binary endpoints

    Pharmaceutical Statistics

    Volume 11, Issue 1, January/February 2012, Pages: 57–62, Chia-Min Chen and Yunchan Chi

    Version of Record online : 8 DEC 2011, DOI: 10.1002/pst.496

  12. A flexible multi-stage design for phase II oncology trials

    Pharmaceutical Statistics

    Volume 10, Issue 4, July/August 2011, Pages: 369–373, Ming T. Tan and Xiaoping Xiong

    Version of Record online : 8 DEC 2010, DOI: 10.1002/pst.478

  13. An evaluation of phase I clinical trial designs in the continuous dose–response setting

    Statistics in Medicine

    Volume 20, Issue 16, 30 August 2001, Pages: 2399–2408, Barry E. Storer

    Version of Record online : 10 AUG 2001, DOI: 10.1002/sim.903

  14. Optimal Design for the Precise Estimation of an Interaction Threshold: The Impact of Exposure to a Mixture of 18 Polyhalogenated Aromatic Hydrocarbons

    Risk Analysis

    Volume 32, Issue 10, October 2012, Pages: 1784–1797, Sharon D. Yeatts, Chris Gennings and Kevin M. Crofton

    Version of Record online : 28 MAY 2012, DOI: 10.1111/j.1539-6924.2012.01834.x

  15. Two-Stage Designs for Gene–Disease Association Studies

    Biometrics

    Volume 58, Issue 1, March 2002, Pages: 163–170, Jaya M. Satagopan, David A. Verbel, E. S. Venkatraman, Kenneth E. Offit and Colin B. Begg

    Version of Record online : 21 MAY 2004, DOI: 10.1111/j.0006-341X.2002.00163.x

  16. Optimized multi-stage designs controlling the false discovery or the family-wise error rate

    Statistics in Medicine

    Volume 27, Issue 21, 20 September 2008, Pages: 4145–4160, Sonja Zehetmayer, Peter Bauer and Martin Posch

    Version of Record online : 28 APR 2008, DOI: 10.1002/sim.3300

  17. Efficient logistic regression designs under an imperfect population identifier

    Biometrics

    Volume 70, Issue 1, March 2014, Pages: 175–184, Paul S. Albert, Aiyi Liu and Tonja Nansel

    Version of Record online : 21 NOV 2013, DOI: 10.1111/biom.12106

  18. Oncology Adaptive Trial Design

    Classical and Adaptive Clinical Trial Designs using Expdesign Studio

    Mark Chang, Pages: 123–148, 2008

    Published Online : 11 JUL 2008, DOI: 10.1002/9780470368718.ch7

  19. Detecting Rare Variant Effects Using Extreme Phenotype Sampling in Sequencing Association Studies

    Genetic Epidemiology

    Volume 37, Issue 2, February 2013, Pages: 142–151, Ian J. Barnett, Seunggeun Lee and Xihong Lin

    Version of Record online : 26 NOV 2012, DOI: 10.1002/gepi.21699

  20. Sequential methods and group sequential designs for comparative clinical trials

    Fundamental & Clinical Pharmacology

    Volume 17, Issue 5, October 2003, Pages: 505–516, Véronique Sébille and Eric Bellissant

    Version of Record online : 18 SEP 2003, DOI: 10.1046/j.1472-8206.2003.00192.x