Search Results

There are 12338 results for: content related to: Next generation analytic tools for large scale genetic epidemiology studies of complex diseases

  1. Using Maximal Segmental Score in Genome-Wide Association Studies

    Genetic Epidemiology

    Volume 36, Issue 6, September 2012, Pages: 594–601, Ying-Chao Lin, Ching-Lin Hsiao, Ai-Ru Hsieh, Ie-Bin Lian and Cathy S.J. Fann

    Article first published online : 16 JUL 2012, DOI: 10.1002/gepi.21652

  2. Dravet syndrome—From epileptic encephalopathy to channelopathy

    Epilepsia

    Volume 55, Issue 7, July 2014, Pages: 979–984, Andreas Brunklaus and Sameer M. Zuberi

    Article first published online : 16 MAY 2014, DOI: 10.1111/epi.12652

  3. Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking

    Genetic Epidemiology

    Volume 37, Issue 8, December 2013, Pages: 846–859, Sarah H. Stephens, Sarah M. Hartz, Nicole R. Hoft, Nancy L. Saccone, Robin C. Corley, John K. Hewitt, Christian J. Hopfer, Naomi Breslau, Hilary Coon, Xiangning Chen, Francesca Ducci, Nicole Dueker, Nora Franceschini, Josef Frank, Younghun Han, Nadia N. Hansel, Chenhui Jiang, Tellervo Korhonen, Penelope A. Lind, Jason Liu, Leo-Pekka Lyytikäinen, Martha Michel, John R. Shaffer, Susan E. Short, Juzhong Sun, Alexander Teumer, John R. Thompson, Nicole Vogelzangs, Jacqueline M. Vink, Angela Wenzlaff, William Wheeler, Bao-Zhu Yang, Steven H. Aggen, Anthony J. Balmforth, Sebastian E. Baumeister, Terri H. Beaty, Daniel J. Benjamin, Andrew W. Bergen, Ulla Broms, David Cesarini, Nilanjan Chatterjee, Jingchun Chen, Yu-Ching Cheng, Sven Cichon, David Couper, Francesco Cucca, Danielle Dick, Tatiana Foroud, Helena Furberg, Ina Giegling, Nathan A. Gillespie, Fangyi Gu, Alistair S. Hall, Jenni Hällfors, Shizhong Han, Annette M. Hartmann, Kauko Heikkilä, Ian B. Hickie, Jouke Jan Hottenga, Pekka Jousilahti, Marika Kaakinen, Mika Kähönen, Philipp D. Koellinger, Stephen Kittner, Bettina Konte, Maria-Teresa Landi, Tiina Laatikainen, Mark Leppert, Steven M. Levy, Rasika A. Mathias, Daniel W. McNeil, Sarah E. Medland, Grant W. Montgomery, Tanda Murray, Matthias Nauck, Kari E. North, Peter D. Paré, Michele Pergadia, Ingo Ruczinski, Veikko Salomaa, Jorma Viikari, Gonneke Willemsen, Kathleen C. Barnes, Eric Boerwinkle, Dorret I. Boomsma, Neil Caporaso, Howard J. Edenberg, Clyde Francks, Joel Gelernter, Hans Jörgen Grabe, Hyman Hops, Marjo-Riitta Jarvelin, Magnus Johannesson, Kenneth S. Kendler, Terho Lehtimäki, Patrik K.E. Magnusson, Mary L. Marazita, Jonathan Marchini, Braxton D. Mitchell, Markus M. Nöthen, Brenda W. Penninx, Olli Raitakari, Marcella Rietschel, Dan Rujescu, Nilesh J. Samani, Ann G. Schwartz, Sanjay Shete, Margaret Spitz, Gary E. Swan, Henry Völzke, Juha Veijola, Qingyi Wei, Chris Amos, Dale S. Cannon, Richard Grucza, Dorothy Hatsukami, Andrew Heath, Eric O. Johnson, Jaakko Kaprio, Pamela Madden, Nicholas G. Martin, Victoria L. Stevens, Robert B. Weiss, Peter Kraft, Laura J. Bierut and Marissa A. Ehringer

    Article first published online : 1 NOV 2013, DOI: 10.1002/gepi.21760

  4. You have full text access to this OnlineOpen article
    Identification of New Genetic Susceptibility Loci for Breast Cancer Through Consideration of Gene-Environment Interactions

    Genetic Epidemiology

    Volume 38, Issue 1, January 2014, Pages: 84–93, Anja Schoeps, Anja Rudolph, Petra Seibold, Alison M. Dunning, Roger L. Milne, Stig E. Bojesen, Anthony Swerdlow, Irene Andrulis, Hermann Brenner, Sabine Behrens, Nicholas Orr, Michael Jones, Alan Ashworth, Jingmei Li, Helen Cramp, Dan Connley, Kamila Czene, Hatef Darabi, Stephen J. Chanock, Jolanta Lissowska, Jonine D. Figueroa, Julia Knight, Gord Glendon, Anna M. Mulligan, Martine Dumont, Gianluca Severi, Laura Baglietto, Janet Olson, Celine Vachon, Kristen Purrington, Matthieu Moisse, Patrick Neven, Hans Wildiers, Amanda Spurdle, Veli-Matti Kosma, Vesa Kataja, Jaana M. Hartikainen, Ute Hamann, Yon-Dschun Ko, Aida K. Dieffenbach, Volker Arndt, Christa Stegmaier, Núria Malats, José I. Arias Perez, Javier Benítez, Henrik Flyger, Børge G. Nordestgaard, Thérèse Truong, Emilie Cordina-Duverger, Florence Menegaux, Isabel dos Santos Silva, Olivia Fletcher, Nichola Johnson, Lothar Häberle, Matthias W. Beckmann, Arif B. Ekici, Linde Braaf, Femke Atsma, Alexandra J. van den Broek, Enes Makalic, Daniel F. Schmidt, Melissa C. Southey, Angela Cox, Jacques Simard, Graham G. Giles, Diether Lambrechts, Arto Mannermaa, Hiltrud Brauch, Pascal Guénel, Julian Peto, Peter A. Fasching, John Hopper, Dieter Flesch-Janys, Fergus Couch, Georgia Chenevix-Trench, Paul D. P. Pharoah, Montserrat Garcia-Closas, Marjanka K. Schmidt, Per Hall, Douglas F. Easton and Jenny Chang-Claude

    Article first published online : 18 NOV 2013, DOI: 10.1002/gepi.21771

  5. Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies

    Genetic Epidemiology

    Volume 36, Issue 1, January 2012, Pages: 3–16, Daniel J. Schaid, Jason P. Sinnwell, Gregory D. Jenkins, Shannon K. McDonnell, James N. Ingle, Michiaki Kubo, Paul E. Goss, Joseph P. Costantino, D. Lawrence Wickerham and Richard M. Weinshilboum

    Article first published online : 7 DEC 2011, DOI: 10.1002/gepi.20632

  6. Estimating the Contributions of Rare and Common Genetic Variations and Clinical Measures to a Model Trait: Adiponectin

    Genetic Epidemiology

    Volume 37, Issue 1, January 2013, Pages: 13–24, S. Sandy An, Nicholette D. Palmer, Anthony J. G. Hanley, Julie T. Ziegler, W. Mark Brown, Steven M. Haffner, Jill M. Norris, Jerome I. Rotter, Xiuqing Guo, Y.-D. Ida Chen, Lynne E. Wagenknecht, Carl D. Langefeld and Donald W. Bowden

    Article first published online : 2 OCT 2012, DOI: 10.1002/gepi.21685

  7. Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry—A Meta-Analysis of Chromosome 15q25

    Genetic Epidemiology

    Volume 36, Issue 4, May 2012, Pages: 340–351, Li-Shiun Chen, Nancy L. Saccone, Robert C. Culverhouse, Paige M. Bracci, Chien-Hsiun Chen, Nicole Dueker, Younghun Han, Hongyan Huang, Guangfu Jin, Takashi Kohno, Jennie Z. Ma, Thomas R. Przybeck, Alan R. Sanders, Jennifer A. Smith, Yun Ju Sung, Angie S. Wenzlaff, Chen Wu, Dankyu Yoon, Ying-Ting Chen, Yu-Ching Cheng, Yoon Shin Cho, Sean P. David, Jubao Duan, Charles B. Eaton, Helena Furberg, Alison M. Goate, Dongfeng Gu, Helen M. Hansen, Sarah Hartz, Zhibin Hu, Young Jin Kim, Steven J. Kittner, Douglas F. Levinson, Thomas H. Mosley, Thomas J. Payne, D. C. Rao, John P. Rice, Treva K. Rice, Tae-Hwi Schwantes-An, Sanjay S. Shete, Jianxin Shi, Margaret R. Spitz, Yan V. Sun, Fuu-Jen Tsai, Jen C. Wang, Margaret R. Wrensch, Hong Xian, Pablo V. Gejman, Jiang He, Steven C. Hunt, Sharon L. Kardia, Ming D. Li, Dongxin Lin, Braxton D. Mitchell, Taesung Park, Ann G. Schwartz, Hongbing Shen, John K. Wiencke, Jer-Yuarn Wu, Jun Yokota, Christopher I. Amos and Laura J. Bierut

    Article first published online : 26 APR 2012, DOI: 10.1002/gepi.21627

  8. Informed Genome-Wide Association Analysis With Family History As a Secondary Phenotype Identifies Novel Loci of Lung Cancer

    Genetic Epidemiology

    Volume 39, Issue 3, March 2015, Pages: 197–206, Julia G. Poirier, Paul Brennan, James D. McKay, Margaret R. Spitz, Heike Bickeböller, Angela Risch, Geoffrey Liu, Loic Le Marchand, Shelley Tworoger, John McLaughlin, Albert Rosenberger, Joachim Heinrich, Irene Brüske, Thomas Muley, Brian E. Henderson, Lynne R. Wilkens, Xuchen Zong, Yafang Li, Ke Hao, Wim Timens, Yohan Bossé, Don D. Sin, Ma'en Obeidat, Christopher I. Amos and Rayjean J. Hung

    Article first published online : 19 JAN 2015, DOI: 10.1002/gepi.21882

  9. A Variational Bayes Discrete Mixture Test for Rare Variant Association

    Genetic Epidemiology

    Volume 38, Issue 1, January 2014, Pages: 21–30, Benjamin A. Logsdon, James Y. Dai, Paul L. Auer, Jill M. Johnsen, Santhi K. Ganesh, Nicholas L. Smith, James G. Wilson, Russell P. Tracy, Leslie A. Lange, Shuo Jiao, Stephen S. Rich, Guillaume Lettre, Christopher S. Carlson, Rebecca D. Jackson, Christopher J. O'Donnell, Mark M. Wurfel, Deborah A. Nickerson, Hua Tang, Alexander P. Reiner, Charles Kooperberg and on behalf of the NHLBI GO Exome Sequencing Project

    Article first published online : 25 NOV 2013, DOI: 10.1002/gepi.21772

  10. Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

    Genetic Epidemiology

    Volume 39, Issue 3, March 2015, Pages: 207–216, Henriët Springelkamp, Aniket Mishra, Pirro G. Hysi, Puya Gharahkhani, René Höhn, Chiea-Chuen Khor, Jessica N. Cooke Bailey, Xiaoyan Luo, Wishal D. Ramdas, Eranga Vithana, Victor Koh, Seyhan Yazar, Liang Xu, Hannah Forward, Lisa S. Kearns, Najaf Amin, Adriana I. Iglesias, Kar-Seng Sim, Elisabeth M. van Leeuwen, Ayse Demirkan, Sven van der Lee, Seng-Chee Loon, Fernando Rivadeneira, Abhishek Nag, Paul G. Sanfilippo, Arne Schillert, Paulus T. V. M. de Jong, Ben A. Oostra, André G. Uitterlinden, Albert Hofman, NEIGHBORHOOD Consortium, Tiger Zhou, Kathryn P. Burdon, Timothy D. Spector, Karl J. Lackner, Seang-Mei Saw, Johannes R. Vingerling, Yik-Ying Teo, Louis R. Pasquale, Roger C. W. Wolfs, Hans G. Lemij, E-Shyong Tai, Jost B. Jonas, Ching-Yu Cheng, Tin Aung, Nomdo M. Jansonius, Caroline C. W. Klaver, Jamie E. Craig, Terri L. Young, Jonathan L. Haines, Stuart MacGregor, David A. Mackey, Norbert Pfeiffer, Tien-Yin Wong, Janey L. Wiggs, Alex W. Hewitt, Cornelia M. van Duijn and Christopher J. Hammond

    Article first published online : 28 JAN 2015, DOI: 10.1002/gepi.21886

  11. Adjusted Sequence Kernel Association Test for Rare Variants Controlling for Cryptic and Family Relatedness

    Genetic Epidemiology

    Volume 37, Issue 4, May 2013, Pages: 366–376, Karim Oualkacha, Zari Dastani, Rui Li, Pablo E. Cingolani, Timothy D. Spector, Christopher J. Hammond, J. Brent Richards, Antonio Ciampi and Celia M. T. Greenwood

    Article first published online : 25 MAR 2013, DOI: 10.1002/gepi.21725

  12. Analysis of 60 Reported Glioma Risk SNPs Replicates Published GWAS Findings but Fails to Replicate Associations From Published Candidate-Gene Studies

    Genetic Epidemiology

    Volume 37, Issue 2, February 2013, Pages: 222–228, Kyle M. Walsh, Erik Anderson, Helen M. Hansen, Paul A. Decker, Matt L. Kosel, Thomas Kollmeyer, Terri Rice, Shichun Zheng, Yuanyuan Xiao, Jeffrey S. Chang, Lucie S. McCoy, Paige M. Bracci, Joe L. Wiemels, Alexander R. Pico, Ivan Smirnov, Daniel H. Lachance, Hugues Sicotte, Jeanette E. Eckel-Passow, John K. Wiencke, Robert B. Jenkins and Margaret R. Wrensch

    Article first published online : 31 DEC 2012, DOI: 10.1002/gepi.21707

  13. You have free access to this content
    Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases

    Genetic Epidemiology

    Volume 39, Issue 1, January 2015, Pages: 11–19, Huann-Sheng Chen, Carolyn M. Hutter, Leah E. Mechanic, Christopher I. Amos, Vineet Bafna, Elizabeth R. Hauser, Ryan D. Hernandez, Chun Li, David A. Liberles, Kimberly McAllister, Jason H. Moore, Dina N. Paltoo, George J. Papanicolaou, Bo Peng, Marylyn D. Ritchie, Gabriel Rosenfeld, John S. Witte, Elizabeth M. Gillanders and Eric J. Feuer

    Article first published online : 4 NOV 2014, DOI: 10.1002/gepi.21870

  14. Methods for Association Analysis and Meta-Analysis of Rare Variants in Families

    Genetic Epidemiology

    Shuang Feng, Giorgio Pistis, He Zhang, Matthew Zawistowski, Antonella Mulas, Magdalena Zoledziewska, Oddgeir L. Holmen, Fabio Busonero, Serena Sanna, Kristian Hveem, Cristen Willer, Francesco Cucca, Dajiang J. Liu and Gonçalo R. Abecasis

    Article first published online : 4 MAR 2015, DOI: 10.1002/gepi.21892

  15. A Genome-Wide Association Study for Venous Thromboembolism: The Extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

    Genetic Epidemiology

    Volume 37, Issue 5, July 2013, Pages: 512–521, Weihong Tang, Martina Teichert, Daniel I. Chasman, John A. Heit, Pierre-Emmanuel Morange, Guo Li, Nathan Pankratz, Frank W. Leebeek, Guillaume Paré, Mariza de Andrade, Christophe Tzourio, Bruce M. Psaty, Saonli Basu, Rikje Ruiter, Lynda Rose, Sebastian M. Armasu, Thomas Lumley, Susan R. Heckbert, André G. Uitterlinden, Mark Lathrop, Kenneth M. Rice, Mary Cushman, Albert Hofman, Jean-Charles Lambert, Nicole L. Glazer, James S. Pankow, Jacqueline C. Witteman, Philippe Amouyel, Joshua C. Bis, Edwin G. Bovill, Xiaoxiao Kong, Russell P. Tracy, Eric Boerwinkle, Jerome I. Rotter, David-Alexandre Trégouët, Daan W. Loth, Bruno H. Ch. Stricker, Paul M. Ridker, Aaron R. Folsom and Nicholas L. Smith

    Article first published online : 5 MAY 2013, DOI: 10.1002/gepi.21731

  16. Evidence for an increase in trisomy 21 (Down syndrome) in Europe after the Chernobyl reactor accident

    Genetic Epidemiology

    Volume 36, Issue 1, January 2012, Pages: 48–55, Karl Sperling, Heidemarie Neitzel and Hagen Scherb

    Article first published online : 7 DEC 2011, DOI: 10.1002/gepi.20662

  17. African Ancestry is a Risk Factor for Asthma and High Total IgE Levels in African Admixed Populations

    Genetic Epidemiology

    Volume 37, Issue 4, May 2013, Pages: 393–401, Candelaria Vergara, Tanda Murray, Nicholas Rafaels, Rachel Lewis, Monica Campbell, Cassandra Foster, Li Gao, Mezbah Faruque, Ricardo Riccio Oliveira, Edgar Carvalho, Maria Ilma Araujo, Alvaro A. Cruz, Harold Watson, Dilia Mercado, Jennifer Knight-Madden, Ingo Ruczinski, Georgia Dunston, Jean Ford, Luis Caraballo, Terri H. Beaty, Rasika A. Mathias and Kathleen C. Barnes

    Article first published online : 2 APR 2013, DOI: 10.1002/gepi.21702

  18. The Case-Only Test for Gene–Environment Interaction is Not Uniformly Powerful: An Empirical Example

    Genetic Epidemiology

    Volume 37, Issue 4, May 2013, Pages: 402–407, Chen Wu, Jiang Chang, Baoshan Ma, Xiaoping Miao, Yifeng Zhou, Yu Liu, Yun Li, Tangchun Wu, Zhibin Hu, Hongbing Shen, Weihua Jia, Yixin Zeng, Dongxin Lin and Peter Kraft

    Article first published online : 13 MAR 2013, DOI: 10.1002/gepi.21713

  19. Whole Genome Prediction of Bladder Cancer Risk With the Bayesian LASSO

    Genetic Epidemiology

    Volume 38, Issue 5, July 2014, Pages: 467–476, Evangelina López de Maturana, Stephen J. Chanok, Antoni C. Picornell, Nathaniel Rothman, Jesús Herranz, M. Luz Calle, Montserrat García-Closas, Gaëlle Marenne, Angela Brand, Adonina Tardón, Alfredo Carrato, Debra T. Silverman, Manolis Kogevinas, Daniel Gianola, Francisco X. Real and Núria Malats

    Article first published online : 5 MAY 2014, DOI: 10.1002/gepi.21809

  20. SBERIA: Set-Based Gene-Environment Interaction Test for Rare and Common Variants in Complex Diseases

    Genetic Epidemiology

    Volume 37, Issue 5, July 2013, Pages: 452–464, Shuo Jiao, Li Hsu, Stéphane Bézieau, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Loic Le Marchand, Mathieu Lemire, Polly A. Newcomb, Martha L. Slattery and Ulrike Peters

    Article first published online : 29 MAY 2013, DOI: 10.1002/gepi.21735