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There are 17400 results for: content related to: Microglia and inflammatory mechanisms in the clearance of amyloid β peptide

  1. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

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    A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis

    Aging Cell

    Volume 11, Issue 3, June 2012, Pages: 530–541, Honoree Mazargui, Christian Lévêque, Dirk Bartnik, Jacques Fantini, Tiphany Gouget, Mariarosa A. B. Melone, Susanne A. Funke, Dieter Willbold and Lorena Perrone

    Version of Record online : 9 APR 2012, DOI: 10.1111/j.1474-9726.2012.00814.x

  3. Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

    Proteins: Structure, Function, and Bioinformatics

    Volume 72, Issue 1, July 2008, Pages: 1–24, Eva Y. Chi, Canay Ege, Amy Winans, Jaroslaw Majewski, Guohui Wu, Kristian Kjaer and Ka Yee C. Lee

    Version of Record online : 10 JAN 2008, DOI: 10.1002/prot.21887

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    Soluble Aβ oligomer production and toxicity

    Journal of Neurochemistry

    Volume 120, Issue s1, January 2012, Pages: 125–139, Megan E. Larson and Sylvain E. Lesné

    Version of Record online : 28 NOV 2011, DOI: 10.1111/j.1471-4159.2011.07478.x

  5. A Strategy for Designing a Peptide Probe for Detection of β-Amyloid Oligomers

    ChemBioChem

    Volume 11, Issue 17, November 22, 2010, Pages: 2409–2418, Yang Hu, Baihao Su, Dr. Chung-Sei Kim, Michael Hernandez, Prof. Agueda Rostagno, Prof. Jorge Ghiso and Prof. Jin Ryoun Kim

    Version of Record online : 28 OCT 2010, DOI: 10.1002/cbic.201000435

  6. The immune system, amyloid-β peptide, and Alzheimer's disease

    Immunological Reviews

    Volume 205, Issue 1, June 2005, Pages: 244–256, Marc E. Weksler, Gunnar Gouras, Norman R. Relkin and Paul Szabo

    Version of Record online : 9 MAY 2005, DOI: 10.1111/j.0105-2896.2005.00264.x

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    A case for a non-transgenic animal model of Alzheimer's disease

    Genes, Brain and Behavior

    Volume 4, Issue 3, April 2005, Pages: 157–172, A. Stéphan and A. G. Phillips

    Version of Record online : 28 JAN 2005, DOI: 10.1111/j.1601-183X.2004.00113.x

  8. Amyloid-β Aggregation with Gold Nanoparticles on Brain Lipid Bilayer

    Small

    Volume 10, Issue 9, May 14, 2014, Pages: 1779–1789, Hyojin Lee, Yuna Kim, Anna Park and Jwa-Min Nam

    Version of Record online : 24 MAR 2014, DOI: 10.1002/smll.201303242

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    Structurally distinct toxicity inhibitors bind at common loci on β-amyloid fibril

    Protein Science

    Volume 19, Issue 12, December 2010, Pages: 2291–2304, Ben Keshet, Jeffrey J. Gray and Theresa A. Good

    Version of Record online : 18 NOV 2010, DOI: 10.1002/pro.509

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    Antibody-based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools

    Journal of Neurochemistry

    Volume 104, Issue 4, February 2008, Pages: 859–874, Peter Lichtlen and M. Hasan Mohajeri

    Version of Record online : 18 AUG 2008, DOI: 10.1111/j.1471-4159.2007.05064.x

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    Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach

    Journal of Neurochemistry

    Volume 85, Issue 6, June 2003, Pages: 1581–1591, Nicolas Sergeant, Stepanie Bombois, Antoine Ghestem, Hervé Drobecq, Vesna Kostanjevecki, Carla Missiaen, Annick Wattez, Jean-Phillipe David, Eugeen Vanmechelen, Christian Sergheraert and André Delacourte

    Version of Record online : 22 MAY 2003, DOI: 10.1046/j.1471-4159.2003.01818.x

  12. Biophysical Studies of the Amyloid β-Peptide: Interactions with Metal Ions and Small Molecules

    ChemBioChem

    Volume 14, Issue 14, September 23, 2013, Pages: 1692–1704, Dr. Sebastian Wärmländer, Dr. Ann Tiiman, Axel Abelein, Jinghui Luo, Dr. Jyri Jarvet, Dr. Kajsa L. Söderberg, Dr. Jens Danielsson and Prof. Astrid Gräslund

    Version of Record online : 26 AUG 2013, DOI: 10.1002/cbic.201300262

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    Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation

    Journal of Neurochemistry

    Volume 81, Issue 3, May 2002, Pages: 481–496, J. Wiltfang, H. Esselmann, M. Bibl, A. Smirnov, M. Otto, S. Paul, B. Schmidt, H.-W. Klafki, M. Maler, T. Dyrks, M. Bienert, M. Beyermann, E. Rüther and J. Kornhuber

    Version of Record online : 29 APR 2002, DOI: 10.1046/j.1471-4159.2002.00818.x

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    Sensitive ELISA detection of amyloid-β protofibrils in biological samples

    Journal of Neurochemistry

    Volume 103, Issue 1, October 2007, Pages: 334–345, Hillevi Englund, Dag Sehlin, Ann-Sofi Johansson, Lars N. G. Nilsson, Pär Gellerfors, Staffan Paulie, Lars Lannfelt and Frida Ekholm Pettersson

    Version of Record online : 9 JUN 2007, DOI: 10.1111/j.1471-4159.2007.04759.x

  15. The use of mass spectrometry to study amyloid-β peptides

    Mass Spectrometry Reviews

    Volume 30, Issue 3, May/June 2011, Pages: 347–365, Giuseppe Grasso

    Version of Record online : 22 NOV 2010, DOI: 10.1002/mas.20281

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    A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease

    Annals of Neurology

    Volume 76, Issue 2, August 2014, Pages: 185–205, Eric Karran and John Hardy

    Version of Record online : 2 JUL 2014, DOI: 10.1002/ana.24188

  17. Oligomeric Aβ in Alzheimer's Disease: Relationship to Plaque and Tangle Pathology, APOE Genotype and Cerebral Amyloid Angiopathy

    Brain Pathology

    Volume 20, Issue 2, March 2010, Pages: 468–480, Zoë Van Helmond, James S. Miners, Patrick G. Kehoe and Seth Love

    Version of Record online : 16 JUL 2009, DOI: 10.1111/j.1750-3639.2009.00321.x

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    Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

    The EMBO Journal

    Volume 30, Issue 11, June 1, 2011, Pages: 2255–2265, Sathish Kumar, Nasrollah Rezaei-Ghaleh, Dick Terwel, Dietmar R Thal, Mélisande Richard, Michael Hoch, Jessica M Mc Donald, Ullrich Wüllner, Konstantin Glebov, Michael T Heneka, Dominic M Walsh, Markus Zweckstetter and Jochen Walter

    Version of Record online : 28 APR 2011, DOI: 10.1038/emboj.2011.138

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    Copper-dependent inhibition of cytochrome c oxidase by Aβ1−42 requires reduced methionine at residue 35 of the Aβ peptide

    Journal of Neurochemistry

    Volume 99, Issue 1, October 2006, Pages: 226–236, Peter J. Crouch, Kevin J. Barnham, James A. Duce, Rachel E. Blake, Colin L. Masters and Ian A. Trounce

    Version of Record online : 20 JUL 2006, DOI: 10.1111/j.1471-4159.2006.04050.x

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    Restored degradation of the Alzheimer’s amyloid-β peptide by targeting amyloid formation

    Journal of Neurochemistry

    Volume 108, Issue 5, March 2009, Pages: 1198–1207, Peter J. Crouch, Deborah J. Tew, Tai Du, Diem Ngoc Nguyen, Aphrodite Caragounis, Gulay Filiz, Rachel E. Blake, Ian A. Trounce, Cynthia P. W. Soon, Katrina Laughton, Keyla A. Perez, Qiao-Xin Li, Robert A. Cherny, Colin L. Masters, Kevin J. Barnham and Anthony R. White

    Version of Record online : 7 JAN 2009, DOI: 10.1111/j.1471-4159.2009.05870.x