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There are 6035 results for: content related to: Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution

  1. You have free access to this content
    Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations

    Hepatology

    Volume 54, Issue 4, October 2011, Pages: 1157–1166, Christoph Neumann-Haefelin, Cesar Oniangue-Ndza, Thomas Kuntzen, Julia Schmidt, Katja Nitschke, John Sidney, Célia Caillet-Saguy, Marco Binder, Nadine Kersting, Michael W. Kemper, Karen A. Power, Susan Ingber, Laura L. Reyor, Kelsey Hills-Evans, Arthur Y. Kim, Georg M. Lauer, Volker Lohmann, Alessandro Sette, Matthew R. Henn, Stéphane Bressanelli, Robert Thimme and Todd M. Allen

    Version of Record online : 6 SEP 2011, DOI: 10.1002/hep.24541

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    Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

    Hepatology

    Volume 51, Issue 1, January 2010, Pages: 54–62, Christoph Neumann-Haefelin, Jörg Timm, Julia Schmidt, Nadine Kersting, Karen Fitzmaurice, Cesar Oniangue-Ndza, Michael N. Kemper, Isla Humphreys, Susan McKiernan, Dermot Kelleher, Volker Lohmann, Paul Bowness, Daniela Huzly, Hugo R. Rosen, Arthur Y. Kim, Georg M. Lauer, Todd M. Allen, Eleanor Barnes, Michael Roggendorf, Hubert E. Blum and Robert Thimme

    Version of Record online : 9 SEP 2009, DOI: 10.1002/hep.23275

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    C-Src is required for complex formation between the hepatitis C virus–encoded proteins NS5A and NS5B: A prerequisite for replication

    Hepatology

    Volume 53, Issue 4, April 2011, Pages: 1127–1136, Andreas Pfannkuche, Katrin Büther, Juliane Karthe, Marion Poenisch, Ralf Bartenschlager, Mirko Trilling, Hartmut Hengel, Dieter Willbold, Dieter Häussinger and Johannes Georg Bode

    Version of Record online : 7 APR 2011, DOI: 10.1002/hep.24214

  4. Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors

    ChemMedChem

    Volume 7, Issue 5, May 2012, Pages: 850–860, Dr. Ravindra Ramesh Deore, Prof. Grace Shiahuy Chen, Dr. Pei-Teh Chang, Ting-Rong Chern, Dr. Shin-Yu Lai, Ming-Hsieh Chuang, Prof. Jung-Hsin Lin, Prof. Fan-Lu Kung, Prof. Chien-Shu Chen, Dr. Chun-Tang Chiou and Prof. Ji-Wang Chern

    Version of Record online : 1 MAR 2012, DOI: 10.1002/cmdc.201200058

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    Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy

    Hepatology

    Volume 49, Issue 4, April 2009, Pages: 1069–1082, Silvana Gaudieri, Andri Rauch, Katja Pfafferott, Eleanor Barnes, Wendy Cheng, Geoff McCaughan, Nick Shackel, Gary P. Jeffrey, Lindsay Mollison, Ross Baker, Hansjakob Furrer, Huldrych F. Günthard, Elizabeth Freitas, Isla Humphreys, Paul Klenerman, Simon Mallal, Ian James, Stuart Roberts, David Nolan and Michaela Lucas

    Version of Record online : 8 DEC 2008, DOI: 10.1002/hep.22773

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    Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B

    FEBS Letters

    Volume 582, Issue 15, June 25, 2008, Pages: 2155–2160, Xiaoyun Wu, You Zhou, Ke Zhang, Qingzhen Liu and Deyin Guo

    Version of Record online : 2 JUN 2008, DOI: 10.1016/j.febslet.2008.05.033

  7. Monoclonal antibody recognizing N-terminal epitope of hepatitis C virus nonstructural 5B inhibits viral RNA replication

    Journal of Viral Hepatitis

    Volume 15, Issue 4, April 2008, Pages: 305–313, S. M. Kang, S. H. Choi, C. Y. Park, M. H. Kim, T. K. Kim, J. M. Park, M. S. Koh, H. J. Kang and S. B. Hwang

    Version of Record online : 12 DEC 2007, DOI: 10.1111/j.1365-2893.2007.00945.x

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    Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen–restricted immune pressure

    Hepatology

    Volume 50, Issue 4, October 2009, Pages: 1017–1029, Andri Rauch, Ian James, Katja Pfafferott, David Nolan, Paul Klenerman, Wendy Cheng, Lindsay Mollison, Geoff McCaughan, Nick Shackel, Gary P. Jeffrey, Ross Baker, Elizabeth Freitas, Isla Humphreys, Hansjakob Furrer, Huldrych F. Günthard, Bernard Hirschel, Simon Mallal, Mina John, Michaela Lucas, Eleanor Barnes and Silvana Gaudieri

    Version of Record online : 29 MAY 2009, DOI: 10.1002/hep.23101

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    Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by cis-acting RNA elements and trans-acting viral factors

    The FEBS Journal

    Volume 275, Issue 16, August 2008, Pages: 4179–4197, Sofia Lourenço, Fleur Costa, Béatrice Débarges, Thibault Andrieu and Annie Cahour

    Version of Record online : 11 JUL 2008, DOI: 10.1111/j.1742-4658.2008.06566.x

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    Direct interaction between α-actinin and hepatitis C virus NS5B

    FEBS Letters

    Volume 554, Issue 3, November 20, 2003, Pages: 289–294, Shuiyun Lan, Hua Wang, Hong Jiang, Hongxia Mao, Xiaoying Liu, Xiaonan Zhang, Yunwen Hu, Li Xiang and Zhenghong Yuan

    Version of Record online : 21 OCT 2003, DOI: 10.1016/S0014-5793(03)01163-3

  11. Site-specific cleavage of HCV genomic RNA and its cloned core and NS5B genes by DNAzyme

    Journal of Gastroenterology and Hepatology

    Volume 24, Issue 5, May 2009, Pages: 872–878, Deepak Kumar, Indrajit Chaudhury, Premashis Kar and Rakha H Das

    Version of Record online : 9 FEB 2009, DOI: 10.1111/j.1440-1746.2008.05717.x

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    Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1727–1737, Yasuhiro Itsui, Naoya Sakamoto, Sei Kakinuma, Mina Nakagawa, Yuko Sekine-Osajima, Megumi Tasaka-Fujita, Yuki Nishimura-Sakurai, Gouki Suda, Yuko Karakama, Kako Mishima, Machi Yamamoto, Takako Watanabe, Mayumi Ueyama, Yusuke Funaoka, Seishin Azuma and Mamoru Watanabe

    Version of Record online : 5 AUG 2009, DOI: 10.1002/hep.23195

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    Specific interaction between the classical swine fever virus NS5B protein and the viral genome

    European Journal of Biochemistry

    Volume 271, Issue 19, October 2004, Pages: 3888–3896, Ming Xiao, Jufang Gao, Wei Wang, Yujing Wang, Jun Chen, Jiakuan Chen and Bo Li

    Version of Record online : 6 SEP 2004, DOI: 10.1111/j.1432-1033.2004.04325.x

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    Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A

    Hepatology

    Volume 50, Issue 1, July 2009, Pages: 25–33, Zhe Liu, John M. Robida, Sreedhar Chinnaswamy, Guanghui Yi, Jason M. Robotham, Heather B. Nelson, Andre Irsigler, C. Cheng Kao and Hengli Tang

    Version of Record online : 6 APR 2009, DOI: 10.1002/hep.22987

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    Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B

    Hepatology

    Volume 46, Issue 4, October 2007, Pages: 1026–1033, Fiona Fernandes, Daniel S. Poole, Spencer Hoover, Rannveig Middleton, Adin-Cristian Andrei, Justin Gerstner and Rob Striker

    Version of Record online : 28 JUN 2007, DOI: 10.1002/hep.21809

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    Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA

    The FEBS Journal

    Volume 272, Issue 15, August 2005, Pages: 3872–3886, Thérèse Astier-Gin, Pantxika Bellecave, Simon Litvak and Michel Ventura

    Version of Record online : 19 JUL 2005, DOI: 10.1111/j.1742-4658.2005.04804.x

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    De novo RNA synthesis by a recombinant classical swine fever virus RNA-dependent RNA polymerase

    European Journal of Biochemistry

    Volume 270, Issue 24, December 2003, Pages: 4952–4961, Guang-Hui Yi, Chu-Yu Zhang, Sheng Cao, Hai-Xiang Wu and Yi Wang

    Version of Record online : 2 DEC 2003, DOI: 10.1046/j.1432-1033.2003.03897.x

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    Genetic and catalytic efficiency structure of an HCV protease quasispecies

    Hepatology

    Volume 45, Issue 4, April 2007, Pages: 899–910, Sandra Franco, Mariona Parera, Ester Aparicio, Bonaventura Clotet and Miguel Angel Martinez

    Version of Record online : 28 MAR 2007, DOI: 10.1002/hep.21623

  19. Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1b infection

    Hepatology Research

    Jun Ito, Goki Suda, Yoshiya Yamamoto, Atsushi Nagasaka, Ken Furuya, Kenichi Kumagai, Hideaki Kikuchi, Takuto Miyagishima, Tomoe Kobayashi, Megumi Kimura, Kazushi Yamasaki, Machiko Umemura, Takaaki Izumi, Seiji Tsunematsu, Fumiyuki Sato, Yoko Tsukuda, Katsumi Terashita, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto and for the NORTE Study Group

    Version of Record online : 8 APR 2016, DOI: 10.1111/hepr.12685

  20. Combined 3D-QSAR, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation Studies on the 5-Hydroxy-2H-Pyridazin-3-One Derivatives as HCV NS5B Polymerase Inhibitors

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 89–105, Haijing Yu, Yu Fang, Xia Lu, Yongjuan Liu and Huabei Zhang

    Version of Record online : 4 OCT 2013, DOI: 10.1111/cbdd.12203