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There are 11883 results for: content related to: Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor β signaling, promoting cirrhosis and hepatocellular carcinoma

  1. You have free access to this content
    Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

    Hepatology

    Volume 49, Issue 4, April 2009, Pages: 1203–1217, Miki Murata, Koichi Matsuzaki, Katsunori Yoshida, Go Sekimoto, Yoshiya Tahashi, Shigeo Mori, Yoshiko Uemura, Noriko Sakaida, Junichi Fujisawa, Toshihito Seki, Kazuki Kobayashi, Koutaro Yokote, Kazuhiko Koike and Kazuichi Okazaki

    Version of Record online : 30 DEC 2008, DOI: 10.1002/hep.22765

  2. Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis

    Inflammatory Bowel Diseases

    Volume 17, Issue 3, March 2011, Pages: 683–695, Seiji Kawamata, Koichi Matsuzaki, Miki Murata, Toshihito Seki, Katsuyoshi Matsuoka, Yasushi Iwao, Toshifumi Hibi and Kazuichi Okazaki

    Version of Record online : 2 JUL 2010, DOI: 10.1002/ibd.21395

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    Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma

    Hepatology

    Volume 49, Issue 6, June 2009, Pages: 1944–1953, Hiromitsu Nagata, Etsuro Hatano, Masaharu Tada, Miki Murata, Koji Kitamura, Hiroyuki Asechi, Masato Narita, Atsuko Yanagida, Nobuyuki Tamaki, Shintaro Yagi, Iwao Ikai, Koichi Matsuzaki and Shinji Uemoto

    Version of Record online : 2 FEB 2009, DOI: 10.1002/hep.22860

  4. You have free access to this content
    Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection

    Clinical & Experimental Immunology

    Volume 176, Issue 1, April 2014, Pages: 102–111, Y.-R. Deng, K. Yoshida, Q. L. Jin, M. Murata, T. Yamaguchi, K. Tsuneyama, Y. Moritoki, J. Q. Niu, K. Matsuzaki and Z.-X. Lian

    Version of Record online : 6 MAR 2014, DOI: 10.1111/cei.12259

  5. Phosphorylated Smad2 and Smad3 signaling: Shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C

    Hepatology Research

    Volume 43, Issue 12, December 2013, Pages: 1327–1342, Takashi Yamaguchi, Koichi Matsuzaki, Ryosuke Inokuchi, Rinako Kawamura, Katsunori Yoshida, Miki Murata, Junichi Fujisawa, Nobuyoshi Fukushima, Michio Sata, Masayoshi Kage, Osamu Nakashima, Akihiro Tamori, Norifumi Kawada, Koichi Tsuneyama, Steven Dooley, Toshihito Seki and Kazuichi Okazaki

    Version of Record online : 4 MAR 2013, DOI: 10.1111/hepr.12082

  6. Compound Astragalus and Salvia miltiorrhiza extracts suppress hepatocarcinogenesis by modulating transforming growth factor-β/Smad signaling

    Journal of Gastroenterology and Hepatology

    Volume 29, Issue 6, June 2014, Pages: 1284–1291, Xiangpeng Hu, Wenjuan Rui, Chao Wu, Shufang He, Jiemei Jiang, Xiaoxiang Zhang and Yan Yang

    Version of Record online : 15 MAY 2014, DOI: 10.1111/jgh.12490

  7. Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway

    British Journal of Dermatology

    Volume 166, Issue 3, March 2012, Pages: 564–574, S. He, Y. Yang, X. Liu, W. Huang, X. Zhang, S. Yang and X. Zhang

    Version of Record online : 5 DEC 2011, DOI: 10.1111/j.1365-2133.2011.10674.x

  8. The Purα/Purβ Single-Strand DNA-Binding Proteins Attenuate Smooth-Muscle Actin Gene Transactivation in Myofibroblasts

    Journal of Cellular Physiology

    Volume 229, Issue 9, September 2014, Pages: 1256–1271, Seethalakshmi Hariharan, Robert J. Kelm Jr. and Arthur Roger Strauch

    Version of Record online : 23 MAY 2014, DOI: 10.1002/jcp.24564

  9. Deregulated E2F5/p38/SMAD3 Circuitry Reinforces the Pro-Tumorigenic Switch of TGFβ Signaling in Prostate Cancer

    Journal of Cellular Physiology

    Volume 231, Issue 11, November 2016, Pages: 2482–2492, Subhadipa Majumder, Ankur Bhowal, Sanmitra Basu, Pritha Mukherjee, Urmi Chatterji and Sanghamitra Sengupta

    Version of Record online : 14 MAR 2016, DOI: 10.1002/jcp.25361

  10. Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-β/Smad in HepG2 cell

    Journal of Gastroenterology and Hepatology

    Volume 25, Issue 2, February 2010, Pages: 420–426, Xin Liu, Yan Yang, Xiaoxiang Zhang, Shengxin Xu, Shufang He, Weijuan Huang and Michael S Roberts

    Version of Record online : 27 SEP 2009, DOI: 10.1111/j.1440-1746.2009.05981.x

  11. Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition

    Pigment Cell & Melanoma Research

    Volume 24, Issue 3, June 2011, Pages: 512–524, Karine A. Cohen-Solal, Kim T. Merrigan, Joseph L.-K. Chan, James S. Goydos, Wenjin Chen, David J. Foran, Fang Liu, Ahmed Lasfar and Michael Reiss

    Version of Record online : 28 APR 2011, DOI: 10.1111/j.1755-148X.2011.00858.x

  12. Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis

    The Journal of Pathology

    Volume 224, Issue 4, August 2011, Pages: 461–472, Carlos Medina, Maria Jose Santos-Martinez, Alfredo Santana, Maria Cristina Paz-Cabrera, Michael J Johnston, Marisabel Mourelle, Antonio Salas and Francisco Guarner

    Version of Record online : 4 APR 2011, DOI: 10.1002/path.2870

  13. Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma

    Head & Neck

    Volume 35, Issue 1, January 2013, Pages: 76–85, Wen Xie, Seena Aisner, Soly Baredes, Gangadhar Sreepada, Rasesh Shah and Michael Reiss

    Version of Record online : 24 JAN 2012, DOI: 10.1002/hed.22924

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    Pivotal role of Smad3 in a mouse model of T cell–mediated hepatitis

    Hepatology

    Volume 47, Issue 1, January 2008, Pages: 113–126, Michael Kremer, Ashley W. Perry, Richard J. Milton, Richard A. Rippe, Michael D. Wheeler and Ian N. Hines

    Version of Record online : 19 NOV 2007, DOI: 10.1002/hep.21956

  15. You have free access to this content
    SKI knockdown inhibits human melanoma tumor growth in vivo

    Pigment Cell & Melanoma Research

    Volume 22, Issue 6, December 2009, Pages: 761–772, Dahu Chen, Qiushi Lin, Neil Box, Dennis Roop, Shunsuke Ishii, Koichi Matsuzaki, Tao Fan, Thomas J. Hornyak, Jon A Reed, Ed Stavnezer, Nikolai A. Timchenko and Estela E. Medrano

    Version of Record online : 27 JUL 2009, DOI: 10.1111/j.1755-148X.2009.00603.x

  16. Mechanisms of transforming growth factor β1/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts

    British Journal of Dermatology

    Volume 162, Issue 3, March 2010, Pages: 538–546, S. He, X. Liu, Y. Yang, W. Huang, S. Xu, S. Yang, X. Zhang and M.S. Roberts

    Version of Record online : 22 SEP 2009, DOI: 10.1111/j.1365-2133.2009.09511.x

  17. You have free access to this content
    Ursodeoxycholyl lysophosphatidylethanolamide attenuates hepatofibrogenesis by impairment of TGF-β1/Smad2/3 signalling

    British Journal of Pharmacology

    Volume 171, Issue 22, November 2014, Pages: 5113–5126, Anita Pathil, Jan Mueller, Johannes M Ludwig, Jiliang Wang, Arne Warth, Walee Chamulitrat and Wolfgang Stremmel

    Version of Record online : 5 SEP 2014, DOI: 10.1111/bph.12837

  18. Phosphorylation of Smad2/3 at the specific linker threonine residue indicates slow-cycling esophageal stem-like cells before re-entry to the cell cycle

    Diseases of the Esophagus

    Volume 29, Issue 2, February/March 2016, Pages: 107–115, Y. Takahashi, T. Fukui, M. Kishimoto, R. Suzuki, T. Mitsuyama, K. Sumimoto, T. Okazaki, M. Sakao, Y. Sakaguchi, K. Yoshida, K. Uchida, A. Nishio, K. Matsuzaki and K. Okazaki

    Version of Record online : 29 AUG 2014, DOI: 10.1111/dote.12277

  19. You have free access to this content
    Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β

    The EMBO Journal

    Volume 18, Issue 5, March 1, 1999, Pages: 1280–1291, Xiao Yang, John J. Letterio, Robert J. Lechleider, Lin Chen, Russ Hayman, Hua Gu, Anita B. Roberts and Chuxia Deng

    Version of Record online : 1 MAR 1999, DOI: 10.1093/emboj/18.5.1280

  20. Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid–induced colorectal fibrosis

    European Journal of Clinical Investigation

    Volume 39, Issue 2, February 2009, Pages: 145–156, G. Latella, A. Vetuschi, R. Sferra, G. Zanninelli, A. D’Angelo, V. Catitti, R. Caprilli, K. C. Flanders and E. Gaudio

    Version of Record online : 20 JAN 2009, DOI: 10.1111/j.1365-2362.2008.02076.x