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There are 8574 results for: content related to: Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection

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    Hepatitis C virus – T-cell responses and viral escape mutations

    European Journal of Immunology

    Volume 42, Issue 1, January 2012, Pages: 17–26, Danijela Petrovic, Eugene Dempsey, Derek G. Doherty, Dermot Kelleher and Aideen Long

    Article first published online : 28 NOV 2011, DOI: 10.1002/eji.201141593

  2. You have full text access to this OnlineOpen article
    AASLD Abstracts

    Hepatology

    Volume 56, Issue S1, October 2012, Pages: 191A–1144A,

    Article first published online : 1 OCT 2012, DOI: 10.1002/hep.26040

  3. Mechanistic role of NS4A and substrate in the activation of HCV NS3 protease

    Proteins: Structure, Function, and Bioinformatics

    Volume 79, Issue 8, August 2011, Pages: 2428–2443, Haimei Zhu and James M. Briggs

    Article first published online : 1 JUN 2011, DOI: 10.1002/prot.23064

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    Positive selection of cytotoxic T lymphocyte escape variants during acute hepatitis C virus infection

    European Journal of Immunology

    Volume 35, Issue 9, September 2005, Pages: 2627–2637, Silvia Guglietta, Anna Rosa Garbuglia, Valentina Pacciani, Cristiano Scottà, Maria Paola Perrone, Luca Laurenti, Enea Spada, Alfonso Mele, Maria Rosaria Capobianchi, Gloria Taliani, Antonella Folgori, Alessandra Vitelli, Lionello Ruggeri, Alfredo Nicosia, Enza Piccolella and Paola Del Porto

    Article first published online : 22 AUG 2005, DOI: 10.1002/eji.200526067

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    Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy

    Hepatology

    Volume 49, Issue 4, April 2009, Pages: 1069–1082, Silvana Gaudieri, Andri Rauch, Katja Pfafferott, Eleanor Barnes, Wendy Cheng, Geoff McCaughan, Nick Shackel, Gary P. Jeffrey, Lindsay Mollison, Ross Baker, Hansjakob Furrer, Huldrych F. Günthard, Elizabeth Freitas, Isla Humphreys, Paul Klenerman, Simon Mallal, Ian James, Stuart Roberts, David Nolan and Michaela Lucas

    Article first published online : 8 DEC 2008, DOI: 10.1002/hep.22773

  6. Mechanisms of hepatitis C virus NS3 proteinase inhibitors

    Journal of Viral Hepatitis

    Volume 6, Issue s1, July 1999, Pages: 23–30, R. De Francesco, A. Pessi and C. Steinkühler

    Article first published online : 28 FEB 2002, DOI: 10.1046/j.1365-2893.1999.00002.x

  7. Genetic heterogeneity of the NS3 protease gene in hepatitis C virus genotype 1 from untreated infected patients

    Journal of Medical Virology

    Volume 75, Issue 4, April 2005, Pages: 528–537, Sophie Vallet, Stephanie Gouriou, Jean-Baptiste Nousbaum, Marie-Christine Legrand-Quillien, Alain Goudeau and Bertrand Picard

    Article first published online : 15 FEB 2005, DOI: 10.1002/jmv.20302

  8. The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy

    Journal of Viral Hepatitis

    Volume 6, Issue 3, May 1999, Pages: 165–181, R. Bartenschlager

    Article first published online : 28 FEB 2002, DOI: 10.1046/j.1365-2893.1999.00152.x

  9. Is hepatitis C virus NS3 protease quasispecies heterogeneity predictive of progression from cirrhosis to hepatocellular carcinoma?

    Journal of Viral Hepatitis

    Volume 14, Issue 2, February 2007, Pages: 96–106, S. Vallet, S. Gouriou, G. Nkontchou, H. Hotta, M. Vilerio, M. C. Legrand-Quillien, M. Beaugrand, J. C. Trinchet, J. B. Nousbaum, P. Dény, C. Gaudy, A. Goudeau, B. Picard and C. Payan

    Article first published online : 2 AUG 2006, DOI: 10.1111/j.1365-2893.2006.00773.x

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    Selection of RNA Aptamers that Bind Specifically to the NS3 Protease of Hepatitis C Virus

    European Journal of Biochemistry

    Volume 248, Issue 1, August 1997, Pages: 130–138, Petri T. Urvil, Nobuko Kakiuchi, De-Min Zhou, Kunitada Shimotohno, Penmetcha K. R. Kumar and Satoshi Nishikawa

    Article first published online : 16 JUL 2004, DOI: 10.1111/j.1432-1033.1997.t01-1-00130.x

  11. Genetic immunization and comprehensive screening approaches in HLA-A2 transgenic mice lead to the identification of three novel epitopes in hepatitis C virus NS3 antigen

    Journal of Medical Virology

    Volume 74, Issue 3, November 2004, Pages: 397–405, P. Martin, P. Parroche, L. Chatel, C. Barretto, A. Beck, C. Trépo, C. Bain, Y.C. Lone, G. Inchauspé and Anne Fournillier

    Article first published online : 14 SEP 2004, DOI: 10.1002/jmv.20189

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    DNA Helicase Activity of the Hepatitis C Virus Nonstructural Protein 3

    European Journal of Biochemistry

    Volume 250, Issue 1, November 1997, Pages: 47–54, Yousang Gwack, Dong Wook Kim, Jang H. Han and Joonho Choe

    Article first published online : 23 JUN 2004, DOI: 10.1111/j.1432-1033.1997.00047.x

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    Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

    Protein Science

    Volume 7, Issue 4, April 1998, Pages: 837–847, Youwei Yan, Ying Li, Sanjeev Munshi, Vinod Sardana, James L. Cole, Mohinder Sardana, Lawarence C. Kuo, Zhongguo Chen, Christian Steinkuehler, Licia Tomei and Raffaele De Francesco

    Article first published online : 31 DEC 2008, DOI: 10.1002/pro.5560070402

  14. Distinct quasispecies characteristics and positive selection within precore/core gene in hepatitis B virus HBV associated acute-on-chronic liver failure

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 6, June 2013, Pages: 1040–1046, Li Chen, Cai-Xia Zheng, Ming-hua Lin, Zu-Xiong Huang, Rong-hua Chen, Qin-guang Li, Qing Li and Pan Chen

    Article first published online : 22 MAY 2013, DOI: 10.1111/jgh.12109

  15. Homology modeling and molecular dynamics study of West Nile virus NS3 protease: A molecular basis for the catalytic activity increased by the NS2B cofactor

    Proteins: Structure, Function, and Bioinformatics

    Volume 65, Issue 3, 15 November 2006, Pages: 692–701, Hong Zhou, N. Jiten Singh and Kwang S. Kim

    Article first published online : 13 SEP 2006, DOI: 10.1002/prot.21129

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    Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

    Hepatology

    Volume 54, Issue 3, 2 September 2011, Pages: 781–788, Nobuhiko Hiraga, Michio Imamura, Hiromi Abe, C. Nelson Hayes, Tomohiko Kono, Mayu Onishi, Masataka Tsuge, Shoichi Takahashi, Hidenori Ochi, Eiji Iwao, Naohiro Kamiya, Ichimaro Yamada, Chise Tateno, Katsutoshi Yoshizato, Hirotaka Matsui, Akinori Kanai, Toshiya Inaba, Shinji Tanaka and Kazuaki Chayama

    Article first published online : 2 AUG 2011, DOI: 10.1002/hep.24460

  17. Failure of innate and adaptive immune responses in controlling hepatitis C virus infection

    FEMS Microbiology Reviews

    Volume 36, Issue 3, May 2012, Pages: 663–683, Robert Thimme, Marco Binder and Ralf Bartenschlager

    Article first published online : 4 JAN 2012, DOI: 10.1111/j.1574-6976.2011.00319.x

  18. Impact of highly active antiretroviral therapy on hepatitis C virus protease quasispecies diversity in HIV co-infected patients

    Journal of Medical Virology

    Volume 82, Issue 5, May 2010, Pages: 791–798, Mark A. Winters, Aarthi Chary, Robert Eison, David Asmuth and Mark Holodniy

    Article first published online : 24 MAR 2010, DOI: 10.1002/jmv.21679

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    The effect of prime-site occupancy on the hepatitis C virus NS3 protease structure

    Protein Science

    Volume 11, Issue 9, September 2002, Pages: 2102–2112, Annarita Casbarra, Fabrizio Dal Piaz, Paolo Ingallinella, Stefania Orrù, Piero Pucci, Antonello Pessi and Elisabetta Bianchi

    Article first published online : 13 APR 2009, DOI: 10.1110/ps.0206602

  20. Homology modeling and molecular dynamics simulations of Dengue virus NS2B/NS3 protease: insight into molecular interaction

    Journal of Molecular Recognition

    Volume 23, Issue 3, May/June 2010, Pages: 283–300, Kanin Wichapong, Somsak Pianwanit, Wolfgang Sippl and Sirirat Kokpol

    Article first published online : 19 AUG 2009, DOI: 10.1002/jmr.977