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  1. Valproate (VPA) Metabolites in Various Clinical Conditions of Probable VPA-Associated Hepatotoxicity

    Epilepsia

    Volume 34, Issue 2, March 1993, Pages: 332–346, Hartmut Siemes, H. Nau, K. Schultze, W. Wittfoht, E. Drews, J. Penzien and U. Seidel

    Article first published online : 28 OCT 2005, DOI: 10.1111/j.1528-1157.1993.tb02419.x

  2. Comparative Pharmacodynamics and Brain Distribution of E-δ2-Valproate and Valproate in Rats

    Epilepsia

    Volume 32, Issue 2, April 1991, Pages: 232–241, R. L. O. Semmes and D. D. Shen

    Article first published online : 5 NOV 2007, DOI: 10.1111/j.1528-1157.1991.tb05250.x

  3. Valproic Acid Plasma Concentration Decreases in a Dose-Independent Manner Following Administration of Meropenem: A Retrospective Study

    The Journal of Clinical Pharmacology

    Volume 49, Issue 11, November 2009, Pages: 1363–1369, Mr Simon Haroutiunian, Ms Yael Ratz, Ms Bella Rabinovich, Ms Miriam Adam and Dr Amnon Hoffman

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009334377

  4. Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion

    The Prostate

    Volume 72, Issue 16, 1 December 2012, Pages: 1719–1735, Lukasz Hudak, Patrick Tezeeh, Steffen Wedel, Jasmina Makarević, Eva Juengel, Igor Tsaur, Georg Bartsch, Christoph Wiesner, Axel Haferkamp and Roman A. Blaheta

    Article first published online : 2 APR 2012, DOI: 10.1002/pros.22525

  5. Concentration of Metabolites of Valproic Acid in Plasma of Epileptic Patients

    Epilepsia

    Volume 22, Issue 2, April 1981, Pages: 169–178, W. Löscher

    Article first published online : 5 NOV 2007, DOI: 10.1111/j.1528-1157.1981.tb04098.x

  6. Associations Between Risk Factors for Valproate Hepatotoxicity and Altered Valproate Metabolism

    Epilepsia

    Volume 33, Issue 1, January 1992, Pages: 172–177, Tsuyoshi Kondo, Sunao Kaneko, Koichi Otani, Masayuki Ishida, Takayuki Hirano, Yutaka Fukushima, Hideki Muranaka, Nobuo Koide and Masaru Yokoyama

    Article first published online : 12 AUG 2005, DOI: 10.1111/j.1528-1157.1992.tb02302.x

  7. Valproic acid attenuates blood–spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

    Journal of Neurochemistry

    Volume 121, Issue 5, June 2012, Pages: 818–829, Jee Y. Lee, Hwang S. Kim, Hye Y. Choi, Tae H. Oh, Bong G. Ju and Tae Y. Yune

    Article first published online : 2 APR 2012, DOI: 10.1111/j.1471-4159.2012.07731.x

  8. Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia

    Journal of Neuroscience Research

    Volume 91, Issue 5, May 2013, Pages: 694–705, Wen-Hsin Lu, Chih-Yen Wang, Po-See Chen, Jing-Wen Wang, De-Maw Chuang, Chung-Shi Yang and Shun-Fen Tzeng

    Article first published online : 13 FEB 2013, DOI: 10.1002/jnr.23200

  9. Effect of Valproate Dose on Formation of Hepatotoxic Metabolites

    Epilepsia

    Volume 33, Issue 4, July 1992, Pages: 736–742, Gail D. Anderson, Andrew A. Acheampong, Alan J. Wilensky and René H. Levy

    Article first published online : 12 AUG 2005, DOI: 10.1111/j.1528-1157.1992.tb02355.x

  10. Valproic acid: Growth inhibition of head and neck cancer by induction of terminal differentiation and senescence

    Head & Neck

    Volume 34, Issue 3, March 2012, Pages: 344–353, Chai Phei Gan, Sharifah Hamid, Seen Yii Hor, Rosnah Binti Zain, Siti Mazlipah Ismail, Wan Mahadzir Wan Mustafa, Soo Hwang Teo, Nicholas Saunders and Sok Ching Cheong

    Article first published online : 24 MAR 2011, DOI: 10.1002/hed.21734

  11. You have free access to this content
    Sunday, December 3, 2006 Poster Session II 7:30 a.m.–4:30 p.m.

    Epilepsia

    Volume 47, Issue s4, October 2006, Pages: 119–204,

    Article first published online : 30 OCT 2006, DOI: 10.1111/j.1528-1167.2006.00001_6.x

  12. Identification of Metabolites of Valproic Acid in Serum of Humans, Dog, Rat, and Mouse

    Epilepsia

    Volume 19, Issue 6, December 1978, Pages: 591–602, Cornells Jakobs and Wolfgang Loscher

    Article first published online : 5 NOV 2007, DOI: 10.1111/j.1528-1157.1978.tb05039.x

  13. Alterations in the Renal Excretion of Valproate and Its Metabolites After Chronic Treatment

    Epilepsia

    Volume 32, Issue 1, February 1991, Pages: 146–150, J. Edward Fisher, Heinz Nau and Wolfgang Löscher

    Article first published online : 5 NOV 2007, DOI: 10.1111/j.1528-1157.1991.tb05627.x

  14. Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life?

    Bipolar Disorders

    Volume 11, Issue 3, May 2009, Pages: 256–269, Peixiong Yuan, Giacomo Salvadore, Xiaoxia Li, Lei Zhang, Jing Du, Guang Chen and Husseini K Manji

    Article first published online : 14 APR 2009, DOI: 10.1111/j.1399-5618.2009.00675.x

  15. Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cells

    Pediatric Blood & Cancer

    Volume 59, Issue 7, 15 December 2012, Pages: 1245–1251, Chengzhi Xie, Holly Edwards, Salvatore B. LoGrasso, Steven A. Buck, Larry H. Matherly, Jeffrey W. Taub and Yubin Ge

    Article first published online : 5 APR 2012, DOI: 10.1002/pbc.24152

  16. Characterization of valproic acid-initiated homologous recombination

    Birth Defects Research Part B: Developmental and Reproductive Toxicology

    Volume 89, Issue 2, April 2010, Pages: 124–132, Kevin Sha and Louise M. Winn

    Article first published online : 31 MAR 2010, DOI: 10.1002/bdrb.20236

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    Antiepileptic Drugs: Adult

    Epilepsia

    Volume 46, Issue s8, October 2005, Pages: 167–192,

    Article first published online : 19 OCT 2005, DOI: 10.1111/j.1528-1167.2005.460801_17.x

  18. Fatal Liver Failure in 16 Children with Valproate Therapy

    Epilepsia

    Volume 29, Issue 5, October 1988, Pages: 530–542, D. Scheffner, St. Konig, I. Rauterberg-Ruland, W. Kochen, W. J. Hofmann and St. Unkelbach

    Article first published online : 5 NOV 2007, DOI: 10.1111/j.1528-1157.1988.tb03757.x

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    Topiramate increases the risk of valproic acid–induced encephalopathy

    Epilepsia

    Volume 54, Issue 1, January 2013, Pages: e1–e4, Young Noh, Dong Wook Kim, Kon Chu, Soon-Tae Lee, Keun-Hwa Jung, Hye-Jin Moon and Sang Kun Lee

    Article first published online : 12 JUN 2012, DOI: 10.1111/j.1528-1167.2012.03532.x

  20. Severe Hepatotoxicity During Valproate Therapy: An Update and Report of Eight New Fatalities

    Epilepsia

    Volume 35, Issue 5, September 1994, Pages: 1005–1015, A. St. König, H. Siemes, F. Bläker, E. Boenigk, G. Groß-Selbeck, F. Hanefeld, N. Haas, B. Köhler, W. Koelfen, R. Korinthenberg, E. Kurek, H-G. Lenard, H. Penin, J.M. Penzien, W. Schünke, C. Schultze, U. Stephani, M. Stute, M. Traus, H.-M. Weinmann and W. Scheffner

    Article first published online : 28 OCT 2005, DOI: 10.1111/j.1528-1157.1994.tb02546.x

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