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There are 32755 results for: content related to: Kupffer cells promote hepatic steatosis via interleukin-1β–dependent suppression of peroxisome proliferator-activated receptor α activity

  1. Nuclear Hormone Receptor Medicinal Chemistry

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Peter T.W. Cheng, Ellen Kick and Ranjan Mukherjee

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc191

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    PPARα Regulates Endothelial Progenitor Cell Maturation and Myeloid Lineage Differentiation Through a NADPH Oxidase-Dependent Mechanism in Mice


    Volume 33, Issue 4, April 2015, Pages: 1292–1303, Luisa Vergori, Emilie Lauret, Abderahim Gaceb, Céline Beauvillain, Ramaroson Andriantsitohaina and M. Carmen Martinez

    Version of Record online : 24 MAR 2015, DOI: 10.1002/stem.1924

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    A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats

    British Journal of Pharmacology

    Volume 171, Issue 6, March 2014, Pages: 1462–1471, B N Okine, K Rea, W M Olango, J Price, S Herdman, M K Madasu, M Roche and D P Finn

    Version of Record online : 4 MAR 2014, DOI: 10.1111/bph.12540

  4. Molecular mechanism of allosteric communication in the human PPARα-RXRα heterodimer

    Proteins: Structure, Function, and Bioinformatics

    Volume 78, Issue 4, March 2010, Pages: 873–887, Tuomas Venäläinen, Ferdinand Molnár, Chris Oostenbrink, Carsten Carlberg and Mikael Peräkylä

    Version of Record online : 17 SEP 2009, DOI: 10.1002/prot.22613

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    Ligand-dependent nucleo-cytoplasmic shuttling of peroxisome proliferator-activated receptors, PPARα and PPARγ

    Genes to Cells

    Volume 17, Issue 7, July 2012, Pages: 576–596, Tomoe Umemoto and Yukio Fujiki

    Version of Record online : 31 MAY 2012, DOI: 10.1111/j.1365-2443.2012.01607.x

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    Regulation of peroxisome proliferator-activated receptors (PPAR) α and -γ of rat brain astrocytes in the course of activation by toll-like receptor agonists

    Journal of Neurochemistry

    Volume 134, Issue 1, July 2015, Pages: 113–124, Dmitry V. Chistyakov, Stepan E. Aleshin, Alina A. Astakhova, Marina G. Sergeeva and Georg Reiser

    Version of Record online : 16 APR 2015, DOI: 10.1111/jnc.13101

  7. Modulation of nutrient sensing nuclear hormone receptors promotes weight loss through appetite suppression in mice

    Diabetes, Obesity and Metabolism

    Volume 12, Issue 3, March 2010, Pages: 234–245, M. Perreault, S. Will, D. Panza, T. Gareski, K. Harding, D. Kubasiak, M. Jalenak, K. Gartrell, S. Wang, G. Bollag, D. R. Artis, P. N. Ibrahim, P. Womack, J. J. Lin, E. Saiah, T. S. Mansour, G. P. Vlasuk, D. V. Erbe and J. F. Tobin

    Version of Record online : 22 SEP 2009, DOI: 10.1111/j.1463-1326.2009.01157.x

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    Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet

    British Journal of Pharmacology

    Volume 165, Issue 8, April 2012, Pages: 2692–2706, Xin-Hui Kou, Mei-Feng Zhu, Dai Chen, Yi Lu, Hui-Zhu Song, Jian-Lin Ye and Lin-Feng Yue

    Version of Record online : 23 MAR 2012, DOI: 10.1111/j.1476-5381.2011.01727.x

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    The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice


    Volume 60, Issue 5, November 2014, Pages: 1593–1606, Michal Pawlak, Eric Baugé, William Bourguet, Karolien De Bosscher, Fanny Lalloyer, Anne Tailleux, Corinna Lebherz, Philippe Lefebvre and Bart Staels

    Version of Record online : 1 OCT 2014, DOI: 10.1002/hep.27297

  10. PPARα modulates the TSH β-subunit mRNA expression in thyrotrope TαT1 cells and in a mouse model

    Molecular Nutrition & Food Research

    Volume 57, Issue 3, March 2013, Pages: 376–389, Nicole Wege, Alexandra Schutkowski, Bettina König, Corinna Brandsch, Matthias Weiwad and Gabriele I. Stangl

    Version of Record online : 18 DEC 2012, DOI: 10.1002/mnfr.201200409

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    A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα

    The EMBO Journal

    Volume 17, Issue 23, December 1, 1998, Pages: 6972–6978, Lisa M. Meertens, Kenji S. Miyata, Jonathan D. Cechetto, Richard A. Rachubinski and John P. Capone

    Version of Record online : 1 DEC 1998, DOI: 10.1093/emboj/17.23.6972

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    Characterization of the Hepatic and Splenic Immune Status and Immunoglobulin Synthesis in Aged Male Mice Lacking the Peroxisome Proliferator-Activated Receptor-Alpha (PPARα)

    Scandinavian Journal of Immunology

    Volume 73, Issue 3, March 2011, Pages: 198–207, M. R. Qazi, M. R. Abedi, B. D. Nelson, J. W. DePierre and M. Abedi-Valugerdi

    Version of Record online : 8 FEB 2011, DOI: 10.1111/j.1365-3083.2010.02495.x

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    The dual PPARα/γ agonist aleglitazar increases the number and function of endothelial progenitor cells: implications for vascular function and atherogenesis

    British Journal of Pharmacology

    Volume 171, Issue 10, May 2014, Pages: 2685–2703, C M Werner, S H Schirmer, C Gensch, V Pavlickova, J Pöss, M B Wright, M Böhm and U Laufs

    Version of Record online : 28 APR 2014, DOI: 10.1111/bph.12608

  14. Peroxisome proliferator-activated receptors and inflammation: take it to heart

    Acta Physiologica

    Volume 191, Issue 3, November 2007, Pages: 171–188, P. J. H. Smeets, A. Planavila, G. J. Van Der Vusse and M. Van Bilsen

    Version of Record online : 24 AUG 2007, DOI: 10.1111/j.1748-1716.2007.01752.x

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    PPARα and PPARγ effectively protect against HIV-induced inflammatory responses in brain endothelial cells

    Journal of Neurochemistry

    Volume 107, Issue 2, October 2008, Pages: 497–509, Wen Huang, Geun Bae Rha, Min-Joon Han, Sung Yong Eum, Ibolya E. András, Yu Zhong, Bernhard Hennig and Michal Toborek

    Version of Record online : 14 AUG 2008, DOI: 10.1111/j.1471-4159.2008.05626.x

  16. Activation of the nuclear receptor PPARα regulates lipid metabolism in foetal liver from diabetic rats: implications in diabetes-induced foetal overgrowth

    Diabetes/Metabolism Research and Reviews

    Volume 27, Issue 1, January 2011, Pages: 35–46, Nora Martínez, Verónica White, Melisa Kurtz, Romina Higa, Evangelina Capobianco and Alicia Jawerbaum

    Version of Record online : 11 NOV 2010, DOI: 10.1002/dmrr.1151

  17. Leptin induces hypertrophy through activating the peroxisome proliferator-activated receptor α pathway in cultured neonatal rat cardiomyocytes

    Clinical and Experimental Pharmacology and Physiology

    Volume 37, Issue 11, November 2010, Pages: 1087–1095, Ning Hou, Miao-Shan Luo, Shi-Ming Liu, Hai-Ning Zhang, Qing Xiao, Pu Sun, Gen-Shui Zhang, Jian-Dong Luo and Min-Sheng Chen

    Version of Record online : 26 OCT 2010, DOI: 10.1111/j.1440-1681.2010.05442.x

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    Inhibition of the Actions of Peroxisome Proliferator-activated Receptor α on Obesity by Estrogen


    Volume 15, Issue 6, June 2007, Pages: 1430–1440, Sunhyo Jeong and Michung Yoon

    Version of Record online : 6 SEP 2012, DOI: 10.1038/oby.2007.171

  19. Mode of Action Analysis and Human Relevance of Liver Tumors Induced by PPARα Activation

    Cancer Risk Assessment

    Ching-Hung Hsu, Todd Stedeford, Pages: 439–481, 2010

    Published Online : 5 AUG 2010, DOI: 10.1002/9780470622728.ch17

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    PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure

    British Journal of Pharmacology

    Volume 163, Issue 3, June 2011, Pages: 609–623, Barbara Rinaldi, Maria Donniacuo, Emanuela Esposito, Annalisa Capuano, Loredana Sodano, Emanuela Mazzon, Donatella Di Palma, Irene Paterniti, Salvatore Cuzzocrea and Francesco Rossi

    Version of Record online : 11 MAY 2011, DOI: 10.1111/j.1476-5381.2011.01248.x