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There are 12697 results for: content related to: The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

  1. You have free access to this content
    Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263

    International Journal of Cancer

    Volume 136, Issue 3, 1 February 2015, Pages: 688–698, Gernot Polier, Marco Giaisi, Rebecca Köhler, Wolfgang W. Müller, Christoph Lutz, Eike C. Buss, Peter H. Krammer and Min Li-Weber

    Version of Record online : 13 JUN 2014, DOI: 10.1002/ijc.29009

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    Identification of predictive factors of response to the BH3-mimetic molecule ABT-737: An ex vivo experiment in human serous ovarian carcinoma

    International Journal of Cancer

    Volume 136, Issue 5, 1 March 2015, Pages: E340–E350, Stéphanie Lheureux, Monique N'Diaye, Cécile Blanc-Fournier, Audrey Emmanuelle Dugué, Bénédicte Clarisse, Soizic Dutoit, Florence Giffard, Edwige Abeilard, Mélanie Briand, Alexandre Labiche, Jean-Michel Grellard, Hubert Crouet, Sandrine Martin, Florence Joly and Laurent Poulain

    Version of Record online : 8 AUG 2014, DOI: 10.1002/ijc.29104

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    ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21(CIP1/WAF1) in human cancer cells

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3182–3195, Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu and Wenhua Li

    Version of Record online : 10 JUN 2014, DOI: 10.1111/bph.12659

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    Attacking cancer's Achilles heel: antagonism of anti-apoptotic BCL-2 family members

    The FEBS Journal

    Volume 283, Issue 14, July 2016, Pages: 2661–2675, Joseph T. Opferman

    Version of Record online : 15 SEP 2015, DOI: 10.1111/febs.13472

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    Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding

    British Journal of Pharmacology

    Volume 173, Issue 3, February 2016, Pages: 471–483, Ting Song, Gaobo Chai, Yubo Liu, Xiaoyan Yu, Ziqian Wang and Zhichao Zhang

    Version of Record online : 16 JAN 2016, DOI: 10.1111/bph.13370

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    Resistance to BH3 mimetic S1 in SCLC cells that up-regulate and phosphorylate Bcl-2 through ERK1/2

    British Journal of Pharmacology

    Volume 169, Issue 7, August 2013, Pages: 1612–1623, Yubo Liu, Zhichao Zhang, Ting Song, Furong Liang, Mingzhou Xie and Hongkun Sheng

    Version of Record online : 12 JUL 2013, DOI: 10.1111/bph.12243

  7. Through a glass less darkly: apoptosis and the germinal center response to antigen

    Immunological Reviews

    Volume 247, Issue 1, May 2012, Pages: 93–106, Victor Peperzak, Ingela B. Vikstrom and David M. Tarlinton

    Version of Record online : 13 APR 2012, DOI: 10.1111/j.1600-065X.2012.01123.x

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    Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA

    Pigment Cell & Melanoma Research

    Volume 23, Issue 3, June 2010, Pages: 430–440, Angela M. Keuling, Susan E. Andrew and Victor A. Tron

    Version of Record online : 22 MAR 2010, DOI: 10.1111/j.1755-148X.2010.00698.x

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    Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant small cell lung cancer cell lines

    International Journal of Cancer

    Volume 132, Issue 4, 15 February 2013, Pages: 978–987, Abid R. Mattoo and David J. Fitzgerald

    Version of Record online : 16 AUG 2012, DOI: 10.1002/ijc.27732

  10. Molecular dynamics study of small molecule inhibitors of the Bcl-2 family

    Proteins: Structure, Function, and Bioinformatics

    Volume 79, Issue 9, September 2011, Pages: 2624–2636, Stéphane Acoca, Qizhi Cui, Gordon C. Shore and Enrico O. Purisima

    Version of Record online : 30 JUN 2011, DOI: 10.1002/prot.23083

  11. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1

    ChemMedChem

    Volume 8, Issue 12, December 2013, Pages: 1986–2014, Dr. Xiao Ding, Dr. Yan Li, Li Lv, Mi Zhou, Dr. Li Han, Zhengxi Zhang, Dr. Qian Ba, Dr. Jingquan Li, Prof. Hui Wang, Prof. Hong Liu and Prof. Renxiao Wang

    Version of Record online : 9 OCT 2013, DOI: 10.1002/cmdc.201300316

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    Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1973–1987, M J Roy, A Vom, P E Czabotar and G Lessene

    Version of Record online : 28 MAR 2014, DOI: 10.1111/bph.12431

  13. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1

    Pigment Cell & Melanoma Research

    Volume 28, Issue 2, March 2015, Pages: 161–170, Yubo Liu, Mingzhou Xie, Ting Song, Hongkun Sheng, Xiaoyan Yu and Zhichao Zhang

    Version of Record online : 18 DEC 2014, DOI: 10.1111/pcmr.12325

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    Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737

    Cancer

    Volume 118, Issue 4, 15 February 2012, Pages: 1023–1031, Kensuke Kojima, Seshagiri Duvvuri, Vivian Ruvolo, Felipe Samaniego, Anas Younes and Michael Andreeff

    Version of Record online : 14 JUL 2011, DOI: 10.1002/cncr.26360

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    ABT-737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug-resistance mechanisms

    British Journal of Haematology

    Volume 140, Issue 2, January 2008, Pages: 181–190, Junya Kuroda, Shinya Kimura, Michael Andreeff, Eishi Ashihara, Yuri Kamitsuji, Asumi Yokota, Eri Kawata, Miki Takeuchi, Ruriko Tanaka, Yoshihide Murotani, Yosuke Matsumoto, Hideo Tanaka, Andreas Strasser, Masafumi Taniwaki and Taira Maekawa

    Version of Record online : 20 NOV 2007, DOI: 10.1111/j.1365-2141.2007.06899.x

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    That which does not kill me makes me stronger; combining ERK1/2 pathway inhibitors and BH3 mimetics to kill tumour cells and prevent acquired resistance

    British Journal of Pharmacology

    Volume 169, Issue 8, August 2013, Pages: 1708–1722, Matthew J Sale and Simon J Cook

    Version of Record online : 26 JUL 2013, DOI: 10.1111/bph.12220

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    Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy

    Pigment Cell & Melanoma Research

    Volume 27, Issue 4, July 2014, Pages: 525–539, Nethia Mohana-Kumaran, David S. Hill, John D. Allen and Nikolas K. Haass

    Version of Record online : 9 APR 2014, DOI: 10.1111/pcmr.12242

  18. You have full text access to this OnlineOpen article
    Dimethyl celecoxib sensitizes gastric cancer cells to ABT-737 via AIF nuclear translocation

    Journal of Cellular and Molecular Medicine

    Volume 20, Issue 11, November 2016, Pages: 2148–2159, Bo Zhang, Youyou Yan, Yangling Li, Dan Zhang, Jianmei Zeng, Linling Wang, Mimi Wang and Nengming Lin

    Version of Record online : 4 JUL 2016, DOI: 10.1111/jcmm.12913

  19. Development of 3-Phenyl-N-(2-(3-phenylureido)ethyl)-thiophene-2-sulfonamide Compounds as Inhibitors of Antiapoptotic Bcl-2 Family Proteins

    ChemMedChem

    Volume 9, Issue 7, July 2014, Pages: 1436–1452, Dr. Chengwen Yang, Sha Chen, Mi Zhou, Dr. Yan Li, Yangfeng Li, Zhengxi Zhang, Dr. Zhen Liu, Dr. Qian Ba, Dr. Jingquan Li, Prof. Hui Wang, Prof. Xiaomei Yan, Prof. Dawei Ma and Prof. Renxiao Wang

    Version of Record online : 29 APR 2014, DOI: 10.1002/cmdc.201400058

  20. You have full text access to this OnlineOpen article
    PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cells

    Journal of Cellular and Molecular Medicine

    Volume 17, Issue 3, March 2013, Pages: 377–385, Shudong Zhu, Matthew B. Cohen, Jeffrey D. Bjorge, James W. Mier and Daniel C. Cho

    Version of Record online : 7 FEB 2013, DOI: 10.1111/jcmm.12019

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    Corrigendum: Corrigendum

    Vol. 18, Issue 7, 1490, Version of Record online: 30 JUL 2014