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There are 4119 results for: content related to: Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1

  1. Nuclear Hormone Receptor Medicinal Chemistry

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    Burger's Medicinal Chemistry and Drug Discovery

    Peter T.W. Cheng, Ellen Kick and Ranjan Mukherjee

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc191

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    Nuclear receptors as therapeutic targets in cholestatic liver diseases

    British Journal of Pharmacology

    Volume 156, Issue 1, January 2009, Pages: 7–27, Gernot Zollner and Michael Trauner

    Version of Record online : 24 DEC 2008, DOI: 10.1111/j.1476-5381.2008.00030.x

  3. Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 3, Issue 5, September/October 2011, Pages: 562–587, Michele Vacca, Chiara Degirolamo, Renato Mariani-Costantini, Giuseppe Palasciano and Antonio Moschetta

    Version of Record online : 16 FEB 2011, DOI: 10.1002/wsbm.137

  4. Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal

    Liver International

    Volume 35, Issue 4, April 2015, Pages: 1133–1144, Johannes Schmitt, Bo Kong, Bruno Stieger, Oliver Tschopp, Simon M. Schultze, Monika Rau, Achim Weber, Beat Müllhaupt, Grace L. Guo and Andreas Geier

    Version of Record online : 7 FEB 2014, DOI: 10.1111/liv.12456

  5. Nuclear Receptor Control of Enterohepatic Circulation

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    Comprehensive Physiology

    Frank J. Gonzalez

    Published Online : 1 OCT 2012, DOI: 10.1002/cphy.c120007

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    Organic anion–transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice

    Hepatology

    Volume 53, Issue 1, January 2011, Pages: 272–281, Iván L. Csanaky, Hong Lu, Youcai Zhang, Kenichiro Ogura, Supratim Choudhuri and Curtis D. Klaassen

    Version of Record online : 14 OCT 2010, DOI: 10.1002/hep.23984

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    Activation of LXRs prevents bile acid toxicity and cholestasis in female mice

    Hepatology

    Volume 45, Issue 2, February 2007, Pages: 422–432, Hirdesh Uppal, Simrat P.S. Saini, Antonio Moschetta, Ying Mu, Jie Zhou, Haibiao Gong, Yonggong Zhai, Songrong Ren, George K. Michalopoulos, David J. Mangelsdorf and Wen Xie

    Version of Record online : 26 JAN 2007, DOI: 10.1002/hep.21494

  8. Dietary modification of metabolic pathways via nuclear hormone receptors

    Cell Biochemistry and Function

    Volume 30, Issue 7, October 2012, Pages: 531–551, Gianella Caiozzi, Brian S. Wong and Marie-Louise Ricketts

    Version of Record online : 2 JUL 2012, DOI: 10.1002/cbf.2842

  9. Solute Carrier (SLC) Family Transporters

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    Encyclopedia of Drug Metabolism and Interactions

    Jasminder Sahi, Yurong Lai and Caroline Lee

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm026

  10. Utility of Genetically Modified Animal Models for Drug Metabolism and Drug Transporters

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    Encyclopedia of Drug Metabolism and Interactions

    Andrew Bessire, Kuresh Youdim, Susan Hurst and Caroline A. Lee

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm069

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    Nuclear localization of liver X receptor α and β is differentially regulated

    Journal of Cellular Biochemistry

    Volume 100, Issue 1, 1 January 2007, Pages: 69–85, Kirsten Prüfer and Jeanne Boudreaux

    Version of Record online : 3 AUG 2006, DOI: 10.1002/jcb.21006

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    Liver X Receptors (LXR) as Therapeutic Targets in Dyslipidemia

    Cardiovascular Therapeutics

    Volume 26, Issue 4, Winter 2008, Pages: 297–316, Jerzy Bełtowski

    Version of Record online : 11 NOV 2008, DOI: 10.1111/j.1755-5922.2008.00062.x

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    The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice

    Hepatology

    Volume 44, Issue 2, August 2006, Pages: 368–378, Mélanie Verreault, Kathy Senekeo-Effenberger, Jocelyn Trottier, Jessica A. Bonzo, Julie Bélanger, Jenny Kaeding, Bart Staels, Patrick Caron, Robert H. Tukey and Olivier Barbier

    Version of Record online : 26 JUL 2006, DOI: 10.1002/hep.21259

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    The G protein–coupled receptor G2A: Involvement in hepatic lipid metabolism and gallstone formation in mice

    Hepatology

    Volume 48, Issue 4, October 2008, Pages: 1138–1148, Laura E. Johnson, Marc S. Elias, David T. Bolick, Marcus D. Skaflen, Richard M. Green and Catherine C. Hedrick

    Version of Record online : 27 MAY 2008, DOI: 10.1002/hep.22433

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    FXRE can function as an LXRE in the promoter of human ileal bile acid-binding protein (I-BABP) gene

    FEBS Letters

    Volume 553, Issue 3, October 23, 2003, Pages: 299–303, Jean-François Landrier, Jacques Grober, Julia Demydchuk and Philippe Besnard

    Version of Record online : 25 SEP 2003, DOI: 10.1016/S0014-5793(03)01033-0

  16. CAV1 Prevents Gallbladder Cholesterol Crystallization by Regulating Biosynthesis and Transport of Bile Salts

    Journal of Cellular Biochemistry

    Volume 117, Issue 9, September 2016, Pages: 2118–2127, Guoqiang Xu, Yiqiao Li, Xin Jiang and Hongtan Chen

    Version of Record online : 29 FEB 2016, DOI: 10.1002/jcb.25518

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    A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

    The EMBO Journal

    Volume 34, Issue 2, 14 January 2015, Pages: 184–199, Dong-Hyun Kim, Zhen Xiao, Sanghoon Kwon, Xiaoxiao Sun, Daniel Ryerson, David Tkac, Ping Ma, Shwu-Yuan Wu, Cheng-Ming Chiang, Edward Zhou, H Eric Xu, Jorma J Palvimo, Lin-Feng Chen, Byron Kemper and Jongsook Kim Kemper

    Version of Record online : 25 NOV 2014, DOI: 10.15252/embj.201489527

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    A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR–/– mice

    British Journal of Pharmacology

    Volume 162, Issue 8, April 2011, Pages: 1792–1804, Dacheng Peng, Richard A. Hiipakka, Jing-Tian Xie, Qing Dai, John M. Kokontis, Catherine A. Reardon, Godfrey S. Getz and Shutsung Liao

    Version of Record online : 22 MAR 2011, DOI: 10.1111/j.1476-5381.2011.01202.x

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    Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization

    Hepatology

    Volume 47, Issue 4, April 2008, Pages: 1331–1342, Hirdesh Uppal, Yonggong Zhai, Archana Gangopadhyay, Shaheen Khadem, Songrong Ren, James A. Moser and Wen Xie

    Version of Record online : 19 DEC 2007, DOI: 10.1002/hep.22175

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    An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 9, September 2013, Pages: 3037–3057 , Kyunghee Yang, Kathleen Köck, Alexander Sedykh, Alexander Tropsha and Kim L. R. Brouwer

    Version of Record online : 7 MAY 2013, DOI: 10.1002/jps.23584