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There are 1003 results for: content related to: The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice

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    The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders


    Volume 50, Issue 3, September 2009, Pages: 861–870, Verena Keitel, Kenko Cupisti, Christoph Ullmer, Wolfram T. Knoefel, Ralf Kubitz and Dieter Häussinger

    Article first published online : 17 APR 2009, DOI: 10.1002/hep.23032

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    Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis


    Volume 57, Issue 2, February 2013, Pages: 656–666, Wei-Dong Chen, Donna Yu, Barry M. Forman, Wendong Huang and Yan-Dong Wang

    Article first published online : 5 FEB 2013, DOI: 10.1002/hep.26019

  3. The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain


    Volume 58, Issue 15, 15 November 2010, Pages: 1794–1805, Verena Keitel, Boris Görg, Hans J. Bidmon, Irina Zemtsova, Lina Spomer, Karl Zilles and Dieter Häussinger

    Article first published online : 21 JUL 2010, DOI: 10.1002/glia.21049

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    The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice


    Volume 58, Issue 4, October 2013, Pages: 1451–1460, Noémie Péan, Isabelle Doignon, Isabelle Garcin, Aurore Besnard, Boris Julien, Bingkaï Liu, Sophie Branchereau, Anne Spraul, Catherine Guettier, Lydie Humbert, Kristina Schoonjans, Dominique Rainteau and Thierry Tordjmann

    Article first published online : 19 AUG 2013, DOI: 10.1002/hep.26463

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    Neuro-humoral signalling by bile acids and the TGR5 receptor in the gastrointestinal tract

    The Journal of Physiology

    Volume 592, Issue 14, 15 July 2014, Pages: 2943–2950, Nigel W. Bunnett

    Article first published online : 14 APR 2014, DOI: 10.1113/jphysiol.2014.271155

  6. TGR5 signaling reduces neuroinflammation during hepatic encephalopathy

    Journal of Neurochemistry

    Volume 135, Issue 3, November 2015, Pages: 565–576, Matthew McMillin, Gabriel Frampton, Richard Tobin, Giuseppina Dusio, Jenny Smith, Hope Shin, Karen Newell-Rogers, Stephanie Grant and Sharon DeMorrow

    Article first published online : 10 SEP 2015, DOI: 10.1111/jnc.13243

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    Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway


    Volume 136, Issue 2, June 2012, Pages: 153–162, Riko Ichikawa, Tetsuro Takayama, Kazuaki Yoneno, Nobuhiko Kamada, Mina T. Kitazume, Hajime Higuchi, Katsuyoshi Matsuoka, Mitsuhiro Watanabe, Hiroshi Itoh, Takanori Kanai, Tadakazu Hisamatsu and Toshifumi Hibi

    Article first published online : 23 APR 2012, DOI: 10.1111/j.1365-2567.2012.03554.x

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    Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice


    Volume 60, Issue 3, September 2014, Pages: 1054–1065, Marine Baptissart, Aurélie Vega, Emmanuelle Martinot, Aurélien J. Pommier, Sander M. Houten, Geoffroy Marceau, Angélique de Haze, Silvère Baron, Kristina Schoonjans, Jean-Marc A. Lobaccaro and David H. Volle

    Article first published online : 25 AUG 2014, DOI: 10.1002/hep.27204

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    The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells


    Volume 45, Issue 3, March 2007, Pages: 695–704, Verena Keitel, Roland Reinehr, Petros Gatsios, Claudia Rupprecht, Boris Görg, Oliver Selbach, Dieter Häussinger and Ralf Kubitz

    Article first published online : 26 FEB 2007, DOI: 10.1002/hep.21458

  10. Aberrant DNA methylation of G-protein-coupled bile acid receptor Gpbar1 predicts prognosis of acute-on-chronic hepatitis B liver failure

    Journal of Viral Hepatitis

    Volume 22, Issue 2, February 2015, Pages: 112–119, S. Gao, X.-F. Ji, F. Li, F.-K. Sun, J. Zhao, Y.-C. Fan and K. Wang

    Article first published online : 4 JUL 2014, DOI: 10.1111/jvh.12277

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    TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease


    Volume 139, Issue 1, May 2013, Pages: 19–29, Kazuaki Yoneno, Tadakazu Hisamatsu, Katsuyoshi Shimamura, Nobuhiko Kamada, Riko Ichikawa, Mina T. Kitazume, Maiko Mori, Michihide Uo, Yuka Namikawa, Katsuyoshi Matsuoka, Toshiro Sato, Kazutaka Koganei, Akira Sugita, Takanori Kanai and Toshifumi Hibi

    Article first published online : 8 APR 2013, DOI: 10.1111/imm.12045

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    Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2−/− (Abcb4−/−) mouse cholangiopathy model by promoting biliary HCOmath image output


    Volume 54, Issue 4, October 2011, Pages: 1303–1312, Anna Baghdasaryan, Thierry Claudel, Judith Gumhold, Dagmar Silbert, Luciano Adorini, Aldo Roda, Stefania Vecchiotti, Frank J. Gonzalez, Kristina Schoonjans, Mario Strazzabosco, Peter Fickert and Michael Trauner

    Article first published online : 27 SEP 2011, DOI: 10.1002/hep.24537

  13. Therapeutic potential of Takeda-G-protein-receptor-5 (TGR5) agonists. Hope or hype?

    Diabetes, Obesity and Metabolism

    Volume 18, Issue 5, May 2016, Pages: 439–443, R. J. Hodge and D. J. Nunez

    Article first published online : 17 MAR 2016, DOI: 10.1111/dom.12636

  14. Bile Acid Metabolism and Signaling

    Standard Article

    Comprehensive Physiology

    John Y. L. Chiang

    Published Online : 1 JUL 2013, DOI: 10.1002/cphy.c120023

  15. Design, Synthesis, and Structure–Activity Relationships of 3,4,5-Trisubstituted 4,5-Dihydro-1,2,4-oxadiazoles as TGR5 Agonists


    Volume 8, Issue 7, July 2013, Pages: 1210–1223, Junjie Zhu, Yangliang Ye, Mengmeng Ning, Attila Mándi, Ying Feng, Qingan Zou, Dr. Tibor Kurtán, Prof. Dr. Ying Leng and Prof. Dr. Jianhua Shen

    Article first published online : 11 JUN 2013, DOI: 10.1002/cmdc.201300144

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    The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon

    Neurogastroenterology & Motility

    Volume 25, Issue 8, August 2013, Pages: 708–711, J. B. J. Ward, M. S. Mroz and S. J. Keely

    Article first published online : 1 MAY 2013, DOI: 10.1111/nmo.12148

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    Bile acids reach out to the spinal cord: New insights to the pathogenesis of itch and analgesia in cholestatic liver disease


    Volume 59, Issue 4, April 2014, Pages: 1638–1641, Paul A. Dawson and Saul J. Karpen

    Article first published online : 14 FEB 2014, DOI: 10.1002/hep.26786

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    Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders

    Neurogastroenterology & Motility

    Volume 23, Issue 11, November 2011, Pages: 995–e458, M. Camilleri, M. I. Vazquez-Roque, P. Carlson, D. Burton, B. S. Wong and A. R. Zinsmeister

    Article first published online : 24 AUG 2011, DOI: 10.1111/j.1365-2982.2011.01772.x

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    Poster Session 2: Donor and Allocation Issues: Living Donor and Split Liver Transplantation and Hepatobiliary Surgery; Experimental Steatohepatitis


    Volume 62, Issue S1, October 2015, Pages: 624A–690A,

    Article first published online : 7 OCT 2015, DOI: 10.1002/hep.28219

  20. You have full text access to this OnlineOpen article
    Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum


    Volume 63, Issue 4, April 2016, Pages: 1287–1298, Shadi Abu-Hayyeh, Caroline Ovadia, TinaMarie Lieu, Dane D. Jensen, Jenny Chambers, Peter H. Dixon, Anita Lövgren-Sandblom, Ruth Bolier, Dagmar Tolenaars, Andreas E. Kremer, Argyro Syngelaki, Muna Noori, David Williams, Jose J.G. Marin, Maria J. Monte, Kypros H. Nicolaides, Ulrich Beuers, Ronald Oude-Elferink, Paul T. Seed, Lucy Chappell, Hanns-Ulrich Marschall, Nigel W. Bunnett and Catherine Williamson

    Article first published online : 28 DEC 2015, DOI: 10.1002/hep.28265