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There are 15707 results for: content related to: Clinical significance of azathioprine metabolites for the maintenance of remission in autoimmune hepatitis

  1. You have free access to this content
    Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

    British Journal of Clinical Pharmacology

    Volume 48, Issue 6, December 1999, Pages: 793–800, Dervieux, Médard, Baudouin, Maisin, Zhang, Broly, Loirat and Jacqz-Aigrain

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00087.x

  2. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice

    Internal Medicine Journal

    Volume 35, Issue 10, October 2005, Pages: 580–585, R. B. Gearry, 1,2 M. L. Barclay, 1,2,3 R. L. Roberts, 4 J. Harraway, 5 M. Zhang, 3,5 L. S. Pike, 5 P. M. George and 5 C. M. Florkowski 5

    Article first published online : 6 OCT 2005, DOI: 10.1111/j.1445-5994.2005.00904.x

  3. You have free access to this content
    High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment

    Alimentary Pharmacology & Therapeutics

    Volume 35, Issue 10, May 2012, Pages: 1181–1189, R. van Egmond, P. Chin, M. Zhang, C. W. Sies and M. L. Barclay

    Article first published online : 4 APR 2012, DOI: 10.1111/j.1365-2036.2012.05084.x

  4. 5-Aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprine

    Inflammatory Bowel Diseases

    Volume 12, Issue 4, April 2006, Pages: 251–257, Scott Hande, Noah Wilson-Rich, Athos Bousvaros, Anna Zholudev, Rie Maurer, Peter Banks, Frederick Makrauer, Sarathchandra Reddy, Robert Burakoff and Sonia Friedman

    Article first published online : 14 DEC 2006, DOI: 10.1097/01.MIB.0000206544.05661.9f

  5. You have free access to this content
    Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanine

    British Journal of Pharmacology

    Volume 163, Issue 4, June 2011, Pages: 722–731, B Jharap, NKH de Boer, RM Vos, K Smid, A Zwiers, GJ Peters, CJJ Mulder, AJ Wilhelm and AA van Bodegraven

    Article first published online : 26 MAY 2011, DOI: 10.1111/j.1476-5381.2011.01265.x

  6. Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 24, Issue 7, July 2009, Pages: 1258–1264, Noritaka Takatsu, Toshiyuki Matsui, Yuji Murakami, Hiroshi Ishihara, Takashi Hisabe, Takashi Nagahama, Shinichirou Maki, Takahiro Beppu, Yasuhiro Takaki, Fumihito Hirai and Kenshi Yao

    Article first published online : 29 JUL 2009, DOI: 10.1111/j.1440-1746.2009.05917.x

  7. You have free access to this content
    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  8. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Article first published online : 29 NOV 2014, DOI: 10.1111/bjh.13240

  9. You have free access to this content
    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Article first published online : 20 MAR 2014, DOI: 10.1111/bcp.12226

  10. Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity

    British Journal of Clinical Pharmacology

    Volume 80, Issue 1, July 2015, Pages: 86–100, Kayode Ogungbenro, Leon Aarons and the CRESim & Epi-CRESim Project Groups

    Article first published online : 1 JUN 2015, DOI: 10.1111/bcp.12588

  11. You have free access to this content
    Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy

    British Journal of Clinical Pharmacology

    Volume 71, Issue 4, April 2011, Pages: 575–584, Tiphaine Adam de Beaumais, May Fakhoury, Yves Medard, Said Azougagh, Daolun Zhang, Karima Yakouben and Evelyne Jacqz-Aigrain

    Article first published online : 11 MAR 2011, DOI: 10.1111/j.1365-2125.2010.03867.x

  12. You have free access to this content
    The impact of introducing thioguanine nucleotide monitoring into an inflammatory bowel disease clinic

    International Journal of Clinical Practice

    Volume 67, Issue 2, February 2013, Pages: 161–169, M. Smith, P. Blaker, C. Patel, A. Marinaki, M. Arenas, E. Escuredo, S. Anderson, P. Irving and J. Sanderson

    Article first published online : 17 DEC 2012, DOI: 10.1111/ijcp.12039

  13. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Article first published online : 5 MAY 2015, DOI: 10.1111/bjh.13469

  14. You have free access to this content
    Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 35, Issue 1, January 2012, Pages: 15–36, L. Chouchana, C. Narjoz, P. Beaune, M.-A. Loriot and X. Roblin

    Article first published online : 2 NOV 2011, DOI: 10.1111/j.1365-2036.2011.04905.x

  15. You have free access to this content
    Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy

    British Journal of Pharmacology

    Volume 160, Issue 5, July 2010, Pages: 1083–1091, P de Graaf, NKH de Boer, DR Wong, S Karner, B Jharap, PM Hooymans, AI Veldkamp, CJJ Mulder, AA van Bodegraven and M Schwab

    Article first published online : 5 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00731.x

  16. You have free access to this content
    Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 28, Issue 8, October 2008, Pages: 973–983, A. ANSARI, M. ARENAS, S. M. GREENFIELD, D. MORRIS, J. LINDSAY, K. GILSHENAN, M. SMITH, C. LEWIS, A. MARINAKI, J. DULEY and J. SANDERSON

    Article first published online : 4 JUL 2008, DOI: 10.1111/j.1365-2036.2008.03788.x

  17. You have free access to this content
    6-Tioguanine monitoring in steroid-dependent patients with inflammatory bowel diseases receiving azathioprine

    Alimentary Pharmacology & Therapeutics

    Volume 21, Issue 7, April 2005, Pages: 829–839, X. Roblin, F. Serre-Debeauvais, J.-M. Phelip, J.-L. Faucheron, G. Hardy, A. Chartier, F. Helluwaert, G. Bessard and B. Bonaz

    Article first published online : 24 MAR 2005, DOI: 10.1111/j.1365-2036.2005.02419.x

  18. Relationship between 6-mercaptopurine dose and 6-Thioguanine nucleotide levels in patients with inflammatory bowel disease

    Inflammatory Bowel Diseases

    Volume 13, Issue 4, April 2007, Pages: 380–385, Ahmed Morales, Sandhya Salguti, Chuan L. Miao and James D. Lewis

    Article first published online : 19 DEC 2006, DOI: 10.1002/ibd.20028

  19. You have free access to this content
    Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 43, Issue 8, April 2016, Pages: 863–883, W. Moon and E. V. Loftus Jr

    Article first published online : 14 FEB 2016, DOI: 10.1111/apt.13559

  20. You have free access to this content
    Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 20, Issue 8, August 2005, Pages: 1149–1157, RICHARD B GEARRY and MURRAY L BARCLAY

    Article first published online : 11 MAY 2005, DOI: 10.1111/j.1440-1746.2005.03832.x