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There are 7115 results for: content related to: A needle in a haystack: Identifying biomarkers to personalize systemic therapy in patients with hepatocellular carcinoma

  1. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 12, December 2013, Pages: 1834–1841, Daisuke Miyaki, Hiroshi Aikata, Hiromi Kan, Hatsue Fujino, Ayako Urabe, Keiichi Masaki, Takayuki Fukuhara, Tomoki Kobayashi, Noriaki Naeshiro, Takashi Nakahara, Tomokazu Kawaoka, Akira Hiramatsu, Shoichi Takahashi, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama

    Version of Record online : 22 NOV 2013, DOI: 10.1111/jgh.12311

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    Effects of Antitumor Drug Sorafenib on Chick Embryo Development

    The Anatomical Record

    Volume 298, Issue 7, July 2015, Pages: 1271–1281, Yi-Sen Cheng, Xiao-Yu Wang, Guang Wang, Yan Li, Yue-Lei Chen, Man-li Chuai, Kenneth Ka Ho Lee, Xiao-Yan Ding and Xue-song Yang

    Version of Record online : 17 APR 2015, DOI: 10.1002/ar.23155

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    Incidence and Risk of Sorafenib-Induced Hypertension: A Systematic Review and Meta-Analysis

    The Journal of Clinical Hypertension

    Volume 16, Issue 3, March 2014, Pages: 177–185, Yan Li, Shun Li, Yaofeng Zhu, Xinyue Liang, Hui Meng, Jun Chen, Dongqing Zhang, Hu Guo and Benkang Shi

    Version of Record online : 12 MAR 2014, DOI: 10.1111/jch.12273

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    Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal-regulated kinase counteraction

    The FEBS Journal

    Volume 278, Issue 18, September 2011, Pages: 3494–3507, Irena Manov, Yulia Pollak, Rinata Broneshter and Theodore C. Iancu

    Version of Record online : 5 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08271.x

  5. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Version of Record online : 11 JUN 2013, DOI: 10.1002/jcb.24530

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    Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

    Hepatology

    Volume 62, Issue 2, August 2015, Pages: 534–545, Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Version of Record online : 3 JUN 2015, DOI: 10.1002/hep.27859

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Version of Record online : 30 APR 2012, DOI: 10.1002/ijc.27604

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    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Version of Record online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x

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    Sorafenib rechallenge in patients with metastatic renal cell carcinoma

    BJU International

    Volume 110, Issue 6b, September 2012, Pages: E228–E234, Masahiro Nozawa, Yutaka Yamamoto, Takafumi Minami, Nobutaka Shimizu, Yuji Hatanaka, Hidenori Tsuji and Hirotsugu Uemura

    Version of Record online : 14 FEB 2012, DOI: 10.1111/j.1464-410X.2011.10905.x

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    Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

    International Journal of Cancer

    Volume 136, Issue 6, 15 March 2015, Pages: 1434–1444, Floris H. Groenendijk, Wouter W. Mellema, Eline van der Burg, Eva Schut, Michael Hauptmann, Hugo M. Horlings, Stefan M. Willems, Michel M. van den Heuvel, Jos Jonkers, Egbert F. Smit and René Bernards

    Version of Record online : 8 AUG 2014, DOI: 10.1002/ijc.29113

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    A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

    BJU International

    Volume 107, Issue 8, April 2011, Pages: 1190–1199, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders and Camillo Porta

    Version of Record online : 15 NOV 2010, DOI: 10.1111/j.1464-410X.2010.09829.x

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    ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21(CIP1/WAF1) in human cancer cells

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3182–3195, Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu and Wenhua Li

    Version of Record online : 10 JUN 2014, DOI: 10.1111/bph.12659

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    FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per Stål and Jenny Flygare

    Version of Record online : 19 AUG 2015, DOI: 10.1002/prp2.171

  14. Clinical features associated with radiological response to sorafenib in unresectable hepatocellular carcinoma: a large multicenter study in Japan

    Liver International

    Volume 35, Issue 5, May 2015, Pages: 1581–1589, Haruhiko Takeda, Hiroki Nishikawa, Yukio Osaki, Kaoru Tsuchiya, Kouji Joko, Chikara Ogawa, Hiroyoshi Taniguchi, Etsuro Orito, Yasushi Uchida, Namiki Izumi and Japanese Red Cross Liver Study Group

    Version of Record online : 9 JUN 2014, DOI: 10.1111/liv.12591

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib

    Hepatology

    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Version of Record online : 27 AUG 2012, DOI: 10.1002/hep.25872

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    Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice

    Hepatology

    Volume 59, Issue 4, April 2014, Pages: 1435–1447, Yunching Chen, Yuhui Huang, Thomas Reiberger, Annique M. Duyverman, Peigen Huang, Rekha Samuel, Lotte Hiddingh, Sylvie Roberge, Christina Koppel, Gregory Y. Lauwers, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

    Version of Record online : 18 FEB 2014, DOI: 10.1002/hep.26790

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    Sorafenib relieves cell-intrinsic and cell-extrinsic inhibitions of effector T cells in tumor microenvironment to augment antitumor immunity

    International Journal of Cancer

    Volume 134, Issue 2, 15 January 2014, Pages: 319–331, Mei-Ling Chen, Bo-Shiun Yan, Wan-Chih Lu, Mei-Huei Chen, Sung-Liang Yu, Pan-Chyr Yang and Ann-Lii Cheng

    Version of Record online : 30 JUL 2013, DOI: 10.1002/ijc.28362

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Version of Record online : 5 AUG 2009, DOI: 10.1002/hep.23214

  19. Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update

    Hepatology Research

    Volume 42, Issue 6, June 2012, Pages: 523–542, Shuichi Kaneko, Junji Furuse, Masatoshi Kudo, Kenji Ikeda, Masao Honda, Yasunari Nakamoto, Morikazu Onchi, Goshi Shiota, Osamu Yokosuka, Isao Sakaida, Tetsuo Takehara, Yoshiyuki Ueno, Kazumasa Hiroishi, Shuhei Nishiguchi, Hisataka Moriwaki, Kazuhide Yamamoto, Michio Sata, Shuntaro Obi, Shiro Miyayama and Yukinori Imai

    Version of Record online : 8 MAY 2012, DOI: 10.1111/j.1872-034X.2012.00981.x

  20. Effect of treatment with branched-chain amino acids during sorafenib therapy for unresectable hepatocellular carcinoma

    Hepatology Research

    Volume 44, Issue 3, March 2014, Pages: 302–312, Haruhiko Takeda, Hiroki Nishikawa, Eriko Iguchi, Yoshiaki Ohara, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Ryuichi Kita, Toru Kimura and Yukio Osaki

    Version of Record online : 29 APR 2013, DOI: 10.1111/hepr.12125