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There are 11990 results for: content related to: Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction

  1. Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line

    Journal of Gastroenterology and Hepatology

    Volume 29, Issue 6, June 2014, Pages: 1299–1307, Sun Jae Lee, Ji Won Hwang, Hyungshin Yim, Hyung Joon Yim, Sang Uk Woo, Sang Jun Suh, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Ji Hoon Kim, Yeon Seok Seo, Jong Eun Yeon, Sang Woo Lee, Kwan Soo Byun and Soon Ho Um

    Version of Record online : 15 MAY 2014, DOI: 10.1111/jgh.12503

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    Role of Simvastatin on fracture healing and osteoporosis: a systematic review on in vivo investigations

    Clinical and Experimental Pharmacology and Physiology

    Volume 43, Issue 7, July 2016, Pages: 659–684, Ali Moshiri, Ali Mohammad Sharifi and Ahmad Oryan

    Version of Record online : 22 JUN 2016, DOI: 10.1111/1440-1681.12577

  3. The essential role of transient receptor potential vanilloid 1 in simvastatin-induced activation of endothelial nitric oxide synthase and angiogenesis

    Acta Physiologica

    Volume 212, Issue 3, November 2014, Pages: 191–204, K.-H. Su, S.-J. Lin, J. Wei, K.-I. Lee, J.-F. Zhao, S.-K. Shyue and T.-S. Lee

    Version of Record online : 20 SEP 2014, DOI: 10.1111/apha.12378

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    Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents

    The Journal of Physiology

    Volume 590, Issue 24, December 2012, Pages: 6389–6402, Joanne E. Mallinson, Dumitru Constantin-Teodosiu, Philip D. Glaves, Elizabeth A. Martin, Wendy J. Davies, F. Russell Westwood, James E. Sidaway and Paul L. Greenhaff

    Version of Record online : 16 NOV 2012, DOI: 10.1113/jphysiol.2012.238022

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    Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice

    International Journal of Cancer

    Volume 123, Issue 4, 15 August 2008, Pages: 951–957, Soo-Jeong Cho, Joo Sung Kim, Jung Mogg Kim, Jong Yeul Lee, Hyun Chae Jung and In Sung Song

    Version of Record online : 2 JUN 2008, DOI: 10.1002/ijc.23593

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    Simvastatin Suppresses Self-Renewal of Mouse Embryonic Stem Cells by Inhibiting RhoA Geranylgeranylation


    Volume 25, Issue 7, July 2007, Pages: 1654–1663, Mi-Hee Lee, Yee Sook Cho and Yong-Mahn Han

    Version of Record online : 26 APR 2007, DOI: 10.1634/stemcells.2006-0753

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    Simvastatin mitigates increases in risk factors for and the occurrence of cardiac disease following 10 Gy total body irradiation

    Pharmacology Research & Perspectives

    Volume 3, Issue 3, June 2015, Marek Lenarczyk, Jidong Su, Steven T. Haworth, Richard Komorowski, Brian L. Fish, Raymond Q. Migrino, Leanne Harmann, John W. Hopewell, Amy Kronenberg, Shailendra Patel, John E. Moulder and John E. Baker

    Version of Record online : 1 JUN 2015, DOI: 10.1002/prp2.145

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    Addition of simvastatin to cold storage solution prevents endothelial dysfunction in explanted rat livers


    Volume 55, Issue 3, March 2012, Pages: 921–930, Lucia Russo, Jorge Gracia-Sancho, Héctor García-Calderó, Giusi Marrone, Juan Carlos García-Pagán, Guillermo García-Cardeña and Jaime Bosch

    Version of Record online : 13 JAN 2012, DOI: 10.1002/hep.24755

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    Simvastatin induces a central hypotensive effect via Ras-mediated signalling to cause eNOS up-regulation

    British Journal of Pharmacology

    Volume 170, Issue 4, October 2013, Pages: 847–858, Wen-Han Cheng, Wen-Yu Ho, Chien-Feng Chang, Pei-Jung Lu, Pei-Wen Cheng, Tung-Chen Yeh, Ling-Zong Hong, Gwo-Ching Sun, Michael Hsiao and Ching-Jiunn Tseng

    Version of Record online : 1 OCT 2013, DOI: 10.1111/bph.12317

  10. Simvastatin effects on portal-systemic collaterals of portal hypertensive rats

    Journal of Gastroenterology and Hepatology

    Volume 25, Issue 8, August 2010, Pages: 1401–1409, Hui-Chun Huang, Sun-Sang Wang, Jing-Yi Lee, Yi-Chou Chen, Fa-Yauh Lee, Han-Chieh Lin, Ching-Chih Chang and Shou-Dong Lee

    Version of Record online : 29 OCT 2009, DOI: 10.1111/j.1440-1746.2009.06159.x

  11. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin

    Clinical Pharmacology & Therapeutics

    Volume 68, Issue 4, October 2000, Pages: 384–390, Jari J. Lilja, Kari T. Kivistö and Pertti J. Neuvonen

    Version of Record online : 29 OCT 2000, DOI: 10.1067/mcp.2000.110216

  12. Coadministration of Dalcetrapib With Pravastatin, Rosuvastatin, or Simvastatin: No Clinically Relevant Drug-Drug Interactions

    The Journal of Clinical Pharmacology

    Volume 50, Issue 10, October 2010, Pages: 1188–1201, Michael Derks, Markus Abt, Mary Phelan, Lynn Turnbull, Georgina Meneses-Lorente, Nuria Bech, Anne-Marie White and Graeme Parr

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009358709

  13. Effects of simvastatin, atorvastatin, ezetimibe, and ezetimibe + simvastatin combination on the inflammatory process and on the liver metabolic changes of arthritic rats

    Fundamental & Clinical Pharmacology

    Volume 26, Issue 6, December 2012, Pages: 722–734, Lívia Bracht, Carmem Patrícia Barbosa, Silvana Martins Caparroz-Assef, Roberto Kenji Nakamura Cuman, Emy Luiza Ishii-Iwamoto, Adelar Bracht and Ciomar Aparecida Bersani-Amado

    Version of Record online : 31 JUL 2011, DOI: 10.1111/j.1472-8206.2011.00976.x

  14. Simvastatin Does Not Have a Clinically Significant Pharmacokinetic Interaction With Fenofibrate in Humans

    The Journal of Clinical Pharmacology

    Volume 44, Issue 9, September 2004, Pages: 1054–1062, Dr Arthur J. Bergman, Dr Gail Murphy, Ms Joanne Burke, Dr Jamie J. Zhao, Mr Robert Valesky, Ms Lida Liu, Dr Kenneth C. Lasseter, Dr Weili He, Dr Thomayant Prueksaritanont, Mr Yue Qiu, Dr Alan Hartford, Dr Jose M. Vega and Dr John F. Paolini

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270004268044

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    Characterization of endothelial factors involved in the vasodilatory effect of simvastatin in aorta and small mesenteric artery of the rat

    British Journal of Pharmacology

    Volume 131, Issue 6, November 2000, Pages: 1179–1187, Maria Álvarez De Sotomayor, Maria Dolores Herrera, Elisa Marhuenda and Ramaroson Andriantsitohaina

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0703668

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    Autocrine secretion of 15d-PGJ2 mediates simvastatin-induced apoptotic burst in human metastatic melanoma cells

    British Journal of Pharmacology

    Volume 171, Issue 24, December 2014, Pages: 5708–5727, Christine Wasinger, Martin Künzl, Christoph Minichsdorfer, Christoph Höller, Maria Zellner and Martin Hohenegger

    Version of Record online : 1 DEC 2014, DOI: 10.1111/bph.12871

  17. Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts

    Wound Repair and Regeneration

    Volume 22, Issue 1, January-February 2014, Pages: 125–133, Je-Ho Mun, Young-Mi Kim, Byung-Soo Kim, Jae-Ho Kim, Moon-Bum Kim and Hyun-Chang Ko

    Version of Record online : 13 DEC 2013, DOI: 10.1111/wrr.12136

  18. The Effect of Simvastatin on Infection-Induced Inflammatory Response of Human Fetal Membranes

    American Journal of Reproductive Immunology

    Volume 74, Issue 1, July 2015, Pages: 54–61, Sanmaan K. Basraon, Maged M. Costantine, George Saade and Ramkumar Menon

    Version of Record online : 21 FEB 2015, DOI: 10.1111/aji.12372

  19. Grapefruit juice—simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

    Clinical Pharmacology & Therapeutics

    Volume 64, Issue 5, November 1998, Pages: 477–483, Jari J. Lilja, Kari T. Kivistö and Pertti J. Neuvonen

    Version of Record online : 22 NOV 1998, DOI: 10.1016/S0009-9236(98)90130-8

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    Cytostatic Effect of Repeated Exposure to Simvastatin: A Mechanism for Chronic Myotoxicity Revealed by the Use of Mesodermal Progenitors Derived from Human Pluripotent Stem Cells


    Volume 33, Issue 10, October 2015, Pages: 2936–2948, Delphine Peric, Isabel Barragan, Karine Giraud-Triboult, Anne-Laure Egesipe, Laurène Meyniel-Schicklin, Christelle Cousin, Vincent Lotteau, Vincent Petit, Jawida Touhami, Jean-Luc Battini, Marc Sitbon, Christian Pinset, Magnus Ingelman-Sundberg, Delphine Laustriat and Marc Peschanski

    Version of Record online : 6 AUG 2015, DOI: 10.1002/stem.2107