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There are 6701 results for: content related to: Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma

  1. Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

    Hepatology

    Volume 62, Issue 2, August 2015, Pages: 534–545, Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Article first published online : 3 JUN 2015, DOI: 10.1002/hep.27859

  2. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 12, December 2013, Pages: 1834–1841, Daisuke Miyaki, Hiroshi Aikata, Hiromi Kan, Hatsue Fujino, Ayako Urabe, Keiichi Masaki, Takayuki Fukuhara, Tomoki Kobayashi, Noriaki Naeshiro, Takashi Nakahara, Tomokazu Kawaoka, Akira Hiramatsu, Shoichi Takahashi, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama

    Article first published online : 22 NOV 2013, DOI: 10.1111/jgh.12311

  3. You have full text access to this OnlineOpen article
    Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

    International Journal of Cancer

    Volume 136, Issue 6, 15 March 2015, Pages: 1434–1444, Floris H. Groenendijk, Wouter W. Mellema, Eline van der Burg, Eva Schut, Michael Hauptmann, Hugo M. Horlings, Stefan M. Willems, Michel M. van den Heuvel, Jos Jonkers, Egbert F. Smit and René Bernards

    Article first published online : 8 AUG 2014, DOI: 10.1002/ijc.29113

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    A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

    BJU International

    Volume 107, Issue 8, April 2011, Pages: 1190–1199, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders and Camillo Porta

    Article first published online : 15 NOV 2010, DOI: 10.1111/j.1464-410X.2010.09829.x

  5. You have full text access to this OnlineOpen article
    FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per Stål and Jenny Flygare

    Article first published online : 19 AUG 2015, DOI: 10.1002/prp2.171

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib

    Hepatology

    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Article first published online : 27 AUG 2012, DOI: 10.1002/hep.25872

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    Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice

    Hepatology

    Volume 59, Issue 4, April 2014, Pages: 1435–1447, Yunching Chen, Yuhui Huang, Thomas Reiberger, Annique M. Duyverman, Peigen Huang, Rekha Samuel, Lotte Hiddingh, Sylvie Roberge, Christina Koppel, Gregory Y. Lauwers, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

    Article first published online : 18 FEB 2014, DOI: 10.1002/hep.26790

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    Incidence and Risk of Sorafenib-Induced Hypertension: A Systematic Review and Meta-Analysis

    The Journal of Clinical Hypertension

    Volume 16, Issue 3, March 2014, Pages: 177–185, Yan Li, Shun Li, Yaofeng Zhu, Xinyue Liang, Hui Meng, Jun Chen, Dongqing Zhang, Hu Guo and Benkang Shi

    Article first published online : 12 MAR 2014, DOI: 10.1111/jch.12273

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Article first published online : 5 AUG 2009, DOI: 10.1002/hep.23214

  10. Effect of treatment with branched-chain amino acids during sorafenib therapy for unresectable hepatocellular carcinoma

    Hepatology Research

    Volume 44, Issue 3, March 2014, Pages: 302–312, Haruhiko Takeda, Hiroki Nishikawa, Eriko Iguchi, Yoshiaki Ohara, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Ryuichi Kita, Toru Kimura and Yukio Osaki

    Article first published online : 29 APR 2013, DOI: 10.1111/hepr.12125

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    Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal-regulated kinase counteraction

    The FEBS Journal

    Volume 278, Issue 18, September 2011, Pages: 3494–3507, Irena Manov, Yulia Pollak, Rinata Broneshter and Theodore C. Iancu

    Article first published online : 5 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08271.x

  12. Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma

    Molecular Carcinogenesis

    Volume 52, Issue 1, January 2013, Pages: 39–48, Rit Vatsyayan, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi and Sharad S. Singhal

    Article first published online : 17 OCT 2011, DOI: 10.1002/mc.20875

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    Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

    International Journal of Cancer

    Volume 131, Issue 3, 1 August 2012, Pages: 548–557, Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita, Takahiro Kodama, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Naonobu Fujita, Tamotsu Yoshimori and Norio Hayashi

    Article first published online : 12 SEP 2011, DOI: 10.1002/ijc.26374

  14. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Article first published online : 11 JUN 2013, DOI: 10.1002/jcb.24530

  15. Inhibition of myeloid cell leukemia-1: Association with sorafenib-induced apoptosis in human mucoepidermoid carcinoma cells and tumor xenograft

    Head & Neck

    Volume 37, Issue 9, September 2015, Pages: 1326–1335, Hyun-Ju Yu, Ji-Ae Shin, Ji-Youn Jung, Jeong-Seok Nam, In-Sun Hong, Nam-Pyo Cho and Sung-Dae Cho

    Article first published online : 19 JUL 2014, DOI: 10.1002/hed.23749

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Article first published online : 30 APR 2012, DOI: 10.1002/ijc.27604

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    Poster Session 1: Cellular Immunobiology, Preservation, and Cell Transplantation in Transplant; Clinical: Hepatocellular Carcinoma and Cholangiocarcinoma

    Hepatology

    Volume 62, Issue S1, October 2015, Pages: 380A–456A,

    Article first published online : 7 OCT 2015, DOI: 10.1002/hep.28212

  18. You have full text access to this Open Access content
    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Article first published online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x

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    Sorafenib rechallenge in patients with metastatic renal cell carcinoma

    BJU International

    Volume 110, Issue 6b, September 2012, Pages: E228–E234, Masahiro Nozawa, Yutaka Yamamoto, Takafumi Minami, Nobutaka Shimizu, Yuji Hatanaka, Hidenori Tsuji and Hirotsugu Uemura

    Article first published online : 14 FEB 2012, DOI: 10.1111/j.1464-410X.2011.10905.x

  20. Sorafenib treatment following hematopoietic stem cell transplant in pediatric FLT3/ITD acute myeloid leukemia

    Pediatric Blood & Cancer

    Volume 62, Issue 6, June 2015, Pages: 1048–1054, Katherine Tarlock, Bill Chang, Todd Cooper, Thomas Gross, Sumit Gupta, Steven Neudorf, Kathleen Adlard, Phoenix A. Ho, Suzanne McGoldrick, Tanya Watt, Tina Templeman, India Sisler, Amy Garee, Blythe Thomson, Ann Woolfrey, Elihu Estey, Soheil Meshinchi and Jessica A. Pollard

    Article first published online : 8 FEB 2015, DOI: 10.1002/pbc.25437