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There are 5050 results for: content related to: Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma

  1. You have free access to this content
    Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells

    Hepatology

    Volume 57, Issue 6, June 2013, Pages: 2358–2368, Martin Franz Sprinzl, Florian Reisinger, Andreas Puschnik, Marc Ringelhan, Kerstin Ackermann, Daniel Hartmann, Matthias Schiemann, Arndt Weinmann, Peter Robert Galle, Marcus Schuchmann, Helmut Friess, Gerd Otto, Mathias Heikenwalder and Ulrike Protzer

    Article first published online : 12 JUN 2013, DOI: 10.1002/hep.26328

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib

    Hepatology

    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Article first published online : 27 AUG 2012, DOI: 10.1002/hep.25872

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    Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice

    Hepatology

    Volume 59, Issue 4, April 2014, Pages: 1435–1447, Yunching Chen, Yuhui Huang, Thomas Reiberger, Annique M. Duyverman, Peigen Huang, Rekha Samuel, Lotte Hiddingh, Sylvie Roberge, Christina Koppel, Gregory Y. Lauwers, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

    Article first published online : 18 FEB 2014, DOI: 10.1002/hep.26790

  4. Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

    Hepatology

    Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Article first published online : 3 JUN 2015, DOI: 10.1002/hep.27859

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    Sorafenib rechallenge in patients with metastatic renal cell carcinoma

    BJU International

    Volume 110, Issue 6b, September 2012, Pages: E228–E234, Masahiro Nozawa, Yutaka Yamamoto, Takafumi Minami, Nobutaka Shimizu, Yuji Hatanaka, Hidenori Tsuji and Hirotsugu Uemura

    Article first published online : 14 FEB 2012, DOI: 10.1111/j.1464-410X.2011.10905.x

  6. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 12, December 2013, Pages: 1834–1841, Daisuke Miyaki, Hiroshi Aikata, Hiromi Kan, Hatsue Fujino, Ayako Urabe, Keiichi Masaki, Takayuki Fukuhara, Tomoki Kobayashi, Noriaki Naeshiro, Takashi Nakahara, Tomokazu Kawaoka, Akira Hiramatsu, Shoichi Takahashi, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama

    Article first published online : 22 NOV 2013, DOI: 10.1111/jgh.12311

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    Sorafenib inhibits transforming growth factor β1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes

    Hepatology

    Volume 53, Issue 5, May 2011, Pages: 1708–1718, Yue-Lei Chen, Jing Lv, Xiao-Lei Ye, Ming-Yu Sun, Qin Xu, Cheng-Hai Liu, Li-Hua Min, Hui-Ping Li, Ping Liu and Xiaoyan Ding

    Article first published online : 22 APR 2011, DOI: 10.1002/hep.24254

  8. You have full text access to this OnlineOpen article
    GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases

    Journal of Cellular Physiology

    Volume 230, Issue 10, October 2015, Pages: 2552–2578, Jane L. Roberts, Mehrad Tavallai, Aida Nourbakhsh, Abigail Fidanza, Tanya Cruz-Luna, Elizabeth Smith, Paul Siembida, Pascale Plamondon, Kelly A. Cycon, Christopher D. Doern, Laurence Booth and Paul Dent

    Article first published online : 23 JUN 2015, DOI: 10.1002/jcp.25014

  9. MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma

    Liver International

    Volume 35, Issue 3, March 2015, Pages: 1077–1086, Valentina Vaira, Massimo Roncalli, Carlo Carnaghi, Alice Faversani, Marco Maggioni, Claudia Augello, Lorenza Rimassa, Tiziana Pressiani, Gaia Spagnuolo, Luca Di Tommaso, Stefano Fagiuoli, Elena Rota Caremoli, Massimo Barberis, Roberto Labianca, Armando Santoro and Silvano Bosari

    Article first published online : 20 JUL 2014, DOI: 10.1111/liv.12636

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Article first published online : 5 AUG 2009, DOI: 10.1002/hep.23214

  11. CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice

    Hepatology

    Volume 61, Issue 5, May 2015, Pages: 1591–1602, Yunching Chen, Rakesh R. Ramjiawan, Thomas Reiberger, Mei R. Ng, Tai Hato, Yuhui Huang, Hiroki Ochiai, Shuji Kitahara, Elizabeth C. Unan, Tejaswini P. Reddy, Christopher Fan, Peigen Huang, Nabeel Bardeesy, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

    Article first published online : 20 MAR 2015, DOI: 10.1002/hep.27665

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    αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma

    Hepatology

    Volume 57, Issue 6, June 2013, Pages: 2235–2247, Xiao-Yong Huang, Ai-Wu Ke, Guo-Ming Shi, Xin Zhang, Chi Zhang, Ying-Hong Shi, Xiao-Ying Wang, Zhen-Bin Ding, Yong-Sheng Xiao, Jun Yan, Shuang-Jian Qiu, Jia Fan and Jian Zhou

    Article first published online : 14 MAY 2013, DOI: 10.1002/hep.26255

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    Effect of sorafenib on murine liver regeneration

    Hepatology

    Volume 53, Issue 2, February 2011, Pages: 577–586, Caroline Hora, Pamela Romanque and Jean-François F. Dufour

    Article first published online : 4 JAN 2011, DOI: 10.1002/hep.24037

  14. A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells

    International Journal of Cancer

    Volume 136, Issue 4, 15 February, 2015, Pages: E161–E172, Joan Fernando, Andrea Malfettone, Edgar B. Cepeda, Roser Vilarrasa-Blasi, Esther Bertran, Giulia Raimondi, Àngels Fabra, Alberto Alvarez-Barrientos, Pedro Fernández-Salguero, Conrado M. Fernández-Rodríguez, Gianluigi Giannelli, Patricia Sancho and Isabel Fabregat

    Article first published online : 4 AUG 2014, DOI: 10.1002/ijc.29097

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    Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

    International Journal of Cancer

    Volume 131, Issue 3, 1 August 2012, Pages: 548–557, Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita, Takahiro Kodama, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Naonobu Fujita, Tamotsu Yoshimori and Norio Hayashi

    Article first published online : 12 SEP 2011, DOI: 10.1002/ijc.26374

  16. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Article first published online : 11 JUN 2013, DOI: 10.1002/jcb.24530

  17. Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli

    Journal of Cellular Physiology

    Volume 227, Issue 4, April 2012, Pages: 1319–1325, Joan Fernando, Patricia Sancho, Conrado M. Fernández-Rodriguez, José L. Lledó, Laia Caja, Jean S. Campbell, Nelson Fausto and Isabel Fabregat

    Article first published online : 11 JAN 2012, DOI: 10.1002/jcp.22843

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    Cost-effectiveness of sorafenib treatment in field practice for patients with hepatocellular carcinoma

    Hepatology

    Volume 57, Issue 3, March 2013, Pages: 1046–1054, Calogero Cammà, Giuseppe Cabibbo, Salvatore Petta, Marco Enea, Massimo Iavarone, Antonio Grieco, Antonio Gasbarrini, Erica Villa, Claudio Zavaglia, Raffaele Bruno, Massimo Colombo, Antonio Craxì and on behalf of the WEF and the SOFIA study groups

    Article first published online : 12 FEB 2013, DOI: 10.1002/hep.26221

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Article first published online : 30 APR 2012, DOI: 10.1002/ijc.27604

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    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Article first published online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x