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There are 13942 results for: content related to: Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

  1. Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver


    Volume 64, Issue 3, September 2016, Pages: 966–976, Nam-On Ku, Pavel Strnad, Heike Bantel and M. Bishr Omary

    Version of Record online : 4 APR 2016, DOI: 10.1002/hep.28493

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    PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin–myosin binding


    Volume 62, Issue 6, December 2015, Pages: 1858–1869, Raymond Kwan, Lu Chen, Koksun Looi, Guo-Zhong Tao, Sujith V. Weerasinghe, Natasha T. Snider, Mary Anne Conti, Robert S. Adelstein, Qing Xie and M. Bishr Omary

    Version of Record online : 25 AUG 2015, DOI: 10.1002/hep.27965

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    Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation


    Volume 62, Issue 3, September 2015, Pages: 876–886, Nurdan Guldiken, Qin Zhou, Ozlem Kucukoglu, Melanie Rehm, Kateryna Levada, Annika Gross, Raymond Kwan, Laura P. James, Christian Trautwein, M. Bishr Omary and Pavel Strnad

    Version of Record online : 3 JUL 2015, DOI: 10.1002/hep.27891

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    Target biomarker profile for the clinical management of paracetamol overdose

    British Journal of Clinical Pharmacology

    Volume 80, Issue 3, September 2015, Pages: 351–362, A. D. Bastiaan Vliegenthart, Daniel J. Antoine and James W. Dear

    Version of Record online : 29 JUL 2015, DOI: 10.1111/bcp.12699

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    High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8


    Volume 60, Issue 1, July 2014, Pages: 169–178, Ozlem Kucukoglu, Nurdan Guldiken, Yu Chen, Valentyn Usachov, Amin El-Heliebi, Johannes Haybaeck, Helmut Denk, Christian Trautwein and Pavel Strnad

    Version of Record online : 27 MAY 2014, DOI: 10.1002/hep.27068

  6. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts

    Liver International

    Volume 34, Issue 3, March 2014, Pages: 367–378, Petra Thulin, Gunnar Nordahl, Marcus Gry, Getnet Yimer, Eleni Aklillu, Eyasu Makonnen, Getachew Aderaye, Lars Lindquist, C. Mikael Mattsson, Björn Ekblom, Daniel J. Antoine, B. Kevin Park, Stig Linder, Alison H. Harrill, Paul B. Watkins, Björn Glinghammar and Ina Schuppe-Koistinen

    Version of Record online : 14 OCT 2013, DOI: 10.1111/liv.12322

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    Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: Role of E2F1 and transcription factor dimerization partner 2


    Volume 59, Issue 2, February 2014, Pages: 555–566, Bo Wang, Shu-hao Hsu, Xinmei Wang, Huban Kutay, Hemant Kumar Bid, Jianhua Yu, Ramesh K. Ganju, Samson T. Jacob, Mariia Yuneva and Kalpana Ghoshal

    Version of Record online : 20 DEC 2013, DOI: 10.1002/hep.26712

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    Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells


    Volume 59, Issue 1, January 2014, Pages: 78–88, Anne Frentzen, Anggakusuma, Engin Gürlevik, Kathrin Hueging, Sarah Knocke, Corinne Ginkel, Richard J.P. Brown, Markus Heim, Michael T. Dill, Andrea Kröger, Ulrich Kalinke, Lars Kaderali, Florian Kuehnel and Thomas Pietschmann

    Version of Record online : 18 NOV 2013, DOI: 10.1002/hep.26626

  9. The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry


    Volume 64, Issue 5, November 2016, Pages: 1623–1636, Alina Simerzin, Elina Zorde-Khvalevsky, Mila Rivkin, Revital Adar, Jessica Zucman-Rossi, Gabrielle Couchy, Tania Roskams, Olivier Govaere, Moshe Oren, Hilla Giladi and Eithan Galun

    Version of Record online : 25 JUL 2016, DOI: 10.1002/hep.28679

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    Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins

    The EMBO Journal

    Volume 17, Issue 7, April 1, 1998, Pages: 1892–1906, Nam-On Ku, Jian Liao and M.Bishr Omary

    Version of Record online : 1 APR 1998, DOI: 10.1093/emboj/17.7.1892

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    Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells


    Volume 58, Issue 5, November 2013, Pages: 1681–1692, Kyoungsub Song, Chang Han, Jinqiang Zhang, Dongdong Lu, Srikanta Dash, Mark Feitelson, Kyu Lim and Tong Wu

    Version of Record online : 17 SEP 2013, DOI: 10.1002/hep.26514

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    CD73 (ecto-5′-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation


    Volume 58, Issue 5, November 2013, Pages: 1790–1800, Natasha T. Snider, Nicholas W. Griggs, Amika Singla, David S. Moons, Sujith V.W. Weerasinghe, Anna S. Lok, Chunhai Ruan, Charles F. Burant, Hari S. Conjeevaram and M. Bishr Omary

    Version of Record online : 26 AUG 2013, DOI: 10.1002/hep.26525

  13. You have full text access to this OnlineOpen article
    The Effects of Heparins on the Liver: Application of Mechanistic Serum Biomarkers in a Randomized Study in Healthy Volunteers

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 2, August 2012, Pages: 214–220, A H Harrill, J Roach, I Fier, J S Eaddy, C L Kurtz, D J Antoine, D M Spencer, T K Kishimoto, D S Pisetsky, B K Park and P B Watkins

    Version of Record online : 27 JUN 2012, DOI: 10.1038/clpt.2012.40

  14. MicroRNA-122 regulates polyploidization in the murine liver


    Volume 64, Issue 2, August 2016, Pages: 599–615, Shu-hao Hsu, Evan R. Delgado, P. Anthony Otero, Kun-yu Teng, Huban Kutay, Kolin M. Meehan, Justin B. Moroney, Jappmann K. Monga, Nicholas J. Hand, Joshua R. Friedman, Kalpana Ghoshal and Andrew W. Duncan

    Version of Record online : 12 MAY 2016, DOI: 10.1002/hep.28573

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    The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice


    Volume 50, Issue 3, September 2009, Pages: 893–899, Peter Fickert, Andrea Fuchsbichler, Martin Wagner, Dagmar Silbert, Kurt Zatloukal, Helmut Denk and Michael Trauner

    Version of Record online : 11 MAY 2009, DOI: 10.1002/hep.23068

  16. Keratin 18 provides resistance to Fas-mediated liver failure in mice

    European Journal of Clinical Investigation

    Volume 39, Issue 6, June 2009, Pages: 481–488, L. Leifeld, S. Kothe, G. Söhl, M. Hesse, T. Sauerbruch, T. M. Magin and U. Spengler

    Version of Record online : 9 APR 2009, DOI: 10.1111/j.1365-2362.2009.02133.x

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    Keratin 18 overexpression but not phosphorylation or filament organization blocks mouse Mallory body formation


    Volume 45, Issue 1, January 2007, Pages: 88–96, Masaru Harada, Pavel Strnad, Evelyn Z. Resurreccion, Nam-On Ku and M. Bishr Omary

    Version of Record online : 22 DEC 2006, DOI: 10.1002/hep.21471

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    Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome


    Volume 60, Issue 4, October 2014, Pages: 1336–1345, Mitchell R. McGill, Vincent S. Staggs, Matthew R. Sharpe, William M. Lee, Hartmut Jaeschke and Acute Liver Failure Study Group

    Version of Record online : 25 AUG 2014, DOI: 10.1002/hep.27265

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    K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase

    The FEBS Journal

    Volume 272, Issue 16, August 2005, Pages: 4249–4259, Keyna Kobza, Gabriela Camporeale, Brian Rueckert, Alice Kueh, Jacob B. Griffin, Gautam Sarath and Janos Zempleni

    Version of Record online : 3 AUG 2005, DOI: 10.1111/j.1742-4658.2005.04839.x

  20. Monitoring of epithelial cell caspase activation via detection of durable keratin fragment formation

    The Journal of Pathology

    Volume 215, Issue 2, June 2008, Pages: 164–174, G-Z Tao, DH Li, Q Zhou, DM Toivola, P Strnad, N Sandesara, RC Cheung, A Hong and MB Omary

    Version of Record online : 27 FEB 2008, DOI: 10.1002/path.2344