Search Results

There are 5770 results for: content related to: MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC)

  1. You have free access to this content
    Subcellular localization and cytoplasmic complex status of endogenous Keap1

    Genes to Cells

    Volume 12, Issue 10, October 2007, Pages: 1163–1178, Yoriko Watai, Akira Kobayashi, Hiroko Nagase, Mio Mizukami, Justina McEvoy, Jeffrey D. Singer, Ken Itoh and Masayuki Yamamoto

    Version of Record online : 26 SEP 2007, DOI: 10.1111/j.1365-2443.2007.01118.x

  2. FoxO3 inactivation promotes human cholangiocarcinoma tumorigenesis and chemoresistance through Keap1-Nrf2 signaling

    Hepatology

    Volume 63, Issue 6, June 2016, Pages: 1914–1927, Li Guan, Lei Zhang, Zhicheng Gong, Xiaonan Hou, Yuxiu Xu, Xinhua Feng, Hongyang Wang and Han You

    Version of Record online : 15 MAR 2016, DOI: 10.1002/hep.28496

  3. The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update

    Medicinal Research Reviews

    Meng-Chen Lu, Jian-Ai Ji, Zheng-Yu Jiang and Qi-Dong You

    Version of Record online : 18 MAY 2016, DOI: 10.1002/med.21396

  4. You have free access to this content
    Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

    Genes to Cells

    Volume 16, Issue 2, February 2011, Pages: 123–140, Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto

    Version of Record online : 20 JAN 2011, DOI: 10.1111/j.1365-2443.2010.01473.x

  5. Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

    Medicinal Research Reviews

    Volume 32, Issue 4, July 2012, Pages: 687–726, Sadagopan Magesh, Yu Chen and Longqin Hu

    Version of Record online : 1 MAY 2012, DOI: 10.1002/med.21257

  6. Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis

    Hepatology

    Volume 62, Issue 3, September 2015, Pages: 851–862, Patrizia Zavattari, Andrea Perra, Silvia Menegon, Marta Anna Kowalik, Annalisa Petrelli, Maria Maddalena Angioni, Antonia Follenzi, Luca Quagliata, Giovanna Maria Ledda-Columbano, Luigi Terracciano, Silvia Giordano and Amedeo Columbano

    Version of Record online : 22 APR 2015, DOI: 10.1002/hep.27790

  7. You have free access to this content
    NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

    Hepatology

    Volume 59, Issue 6, June 2014, Pages: 2371–2382, Keiichi Shirasaki, Keiko Taguchi, Michiaki Unno, Hozumi Motohashi and Masayuki Yamamoto

    Version of Record online : 25 APR 2014, DOI: 10.1002/hep.27020

  8. Molecular mechanisms of Nrf2-mediated antioxidant response

    Molecular Carcinogenesis

    Volume 48, Issue 2, February 2009, Pages: 91–104, Wenge Li and Ah-Ng Kong

    Version of Record online : 10 JUL 2008, DOI: 10.1002/mc.20465

  9. You have free access to this content
    Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells

    Genes to Cells

    Volume 19, Issue 3, March 2014, Pages: 239–253, Shohei Murakami, Ritsuko Shimizu, Paul-Henri Romeo, Masayuki Yamamoto and Hozumi Motohashi

    Version of Record online : 21 JAN 2014, DOI: 10.1111/gtc.12126

  10. Kinetic Analyses of Keap1–Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance

    Chemical Biology & Drug Design

    Volume 78, Issue 6, December 2011, Pages: 1014–1021, Yu Chen, Daigo Inoyama, Ah-Ng Tony Kong, Lesa J. Beamer and Longqin Hu

    Version of Record online : 31 OCT 2011, DOI: 10.1111/j.1747-0285.2011.01240.x

  11. You have free access to this content
    Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system

    Genes to Cells

    Volume 7, Issue 8, August 2002, Pages: 807–820, Makoto Kobayashi, Ken Itoh, Takafumi Suzuki, Hitoshi Osanai, Keizo Nishikawa, Yasutake Katoh, Yaeko Takagi and Masayuki Yamamoto

    Version of Record online : 7 AUG 2002, DOI: 10.1046/j.1365-2443.2002.00561.x

  12. Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin

    Journal of Pineal Research

    Volume 54, Issue 3, April 2013, Pages: 271–281, Rong-rong Tao, Ji-Yun Huang, Xue-jing Shao, Wei-feng Ye, Yun Tian, Mei-hua Liao, Kohji Fukunaga, Yi-jia Lou, Feng Han and Ying-mei Lu

    Version of Record online : 4 SEP 2012, DOI: 10.1111/jpi.12009

  13. Somatic mutations of the KEAP1 gene in common solid cancers

    Histopathology

    Volume 60, Issue 6, May 2012, Pages: 943–952, Nam Jin Yoo, Hyung Ran Kim, Yoo Ri Kim, Chang Hyeok An and Sug Hyung Lee

    Version of Record online : 20 FEB 2012, DOI: 10.1111/j.1365-2559.2012.04178.x

  14. You have free access to this content
    Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

    The EMBO Journal

    Volume 25, Issue 15, August 9, 2006, Pages: 3605–3617, Shih-Ching Lo, Xuchu Li, Michael T Henzl, Lesa J Beamer and Mark Hannink

    Version of Record online : 3 AUG 2006, DOI: 10.1038/sj.emboj.7601243

  15. You have free access to this content
    The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system

    Hepatology

    Volume 48, Issue 4, October 2008, Pages: 1292–1301, Ian M. Copple, Christopher E. Goldring, Rosalind E. Jenkins, Alvin J. L. Chia, Laura E. Randle, John D. Hayes, Neil R. Kitteringham and B. Kevin Park

    Version of Record online : 19 JUN 2008, DOI: 10.1002/hep.22472

  16. You have free access to this content
    Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1

    Journal of Neurochemistry

    Volume 104, Issue 4, February 2008, Pages: 1116–1131, Takumi Satoh, Kunio Kosaka, Ken Itoh, Akira Kobayashi, Masayuki Yamamoto, Yosuke Shimojo, Chieko Kitajima, Jiankun Cui, Joshua Kamins, Shu-ichi Okamoto, Masanori Izumi, Takuji Shirasawa and Stuart A. Lipton

    Version of Record online : 18 AUG 2008, DOI: 10.1111/j.1471-4159.2007.05039.x

  17. You have full text access to this OnlineOpen article
    UHRF1 regulation of the Keap1–Nrf2 pathway in pancreatic cancer contributes to oncogenesis

    The Journal of Pathology

    Volume 238, Issue 3, February 2016, Pages: 423–433, Wafa Abu-Alainin, Thompson Gana, Triantafillos Liloglou, Adedamola Olayanju, Lawrence N Barrera, Robert Ferguson, Fiona Campbell, Timothy Andrews, Christopher Goldring, Neil Kitteringham, Brian K Park, Taoufik Nedjadi, Michael C Schmid, Joseph R Slupsky, William Greenhalf, John P Neoptolemos and Eithne Costello

    Version of Record online : 30 NOV 2015, DOI: 10.1002/path.4665

  18. You have full text access to this OnlineOpen article
    Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation

    FEBS Open Bio

    Volume 5, Issue 1, January 01, 2015, Pages: 557–570, Mikiya Satoh, Hajime Saburi, Tomoyuki Tanaka, Yoshinori Matsuura, Hisashi Naitow, Rieko Shimozono, Naoyoshi Yamamoto, Hideki Inoue, Noriko Nakamura, Yoshitaka Yoshizawa, Takumi Aoki, Ryuji Tanimura and Naoki Kunishima

    Version of Record online : 30 JUN 2015, DOI: 10.1016/j.fob.2015.06.011

  19. You have free access to this content
    Nrf2 induces fibroblast growth factor 21 in diabetic mice

    Genes to Cells

    Volume 19, Issue 12, December 2014, Pages: 864–878, Yuki Furusawa, Akira Uruno, Yoko Yagishita, Chika Higashi and Masayuki Yamamoto

    Version of Record online : 1 OCT 2014, DOI: 10.1111/gtc.12186

  20. Role of growth hormone in maturation and activation of dendritic cells via miR-200a and the Keap1/Nrf2 pathway

    Cell Proliferation

    Volume 48, Issue 5, October 2015, Pages: 573–581, Qiu-Liang Liu, Jiao Zhang, Xin Liu and Jing-Yao Gao

    Version of Record online : 20 AUG 2015, DOI: 10.1111/cpr.12206