Search Results

There are 8507 results for: content related to: Pathological mechanisms in NAFLD

  1. Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

    Medicinal Research Reviews

    Volume 32, Issue 4, July 2012, Pages: 687–726, Sadagopan Magesh, Yu Chen and Longqin Hu

    Version of Record online : 1 MAY 2012, DOI: 10.1002/med.21257

  2. A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions

    Cell Motility and the Cytoskeleton

    Volume 51, Issue 3, March 2002, Pages: 147–164, Michaella Velichkova, Julian Guttman, Carmen Warren, Lily Eng, Katie Kline, A. Wayne Vogl and Tama Hasson

    Version of Record online : 15 MAR 2002, DOI: 10.1002/cm.10025

  3. Somatic mutations of the KEAP1 gene in common solid cancers


    Volume 60, Issue 6, May 2012, Pages: 943–952, Nam Jin Yoo, Hyung Ran Kim, Yoo Ri Kim, Chang Hyeok An and Sug Hyung Lee

    Version of Record online : 20 FEB 2012, DOI: 10.1111/j.1365-2559.2012.04178.x

  4. You have free access to this content
    The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system


    Volume 48, Issue 4, October 2008, Pages: 1292–1301, Ian M. Copple, Christopher E. Goldring, Rosalind E. Jenkins, Alvin J. L. Chia, Laura E. Randle, John D. Hayes, Neil R. Kitteringham and B. Kevin Park

    Version of Record online : 19 JUN 2008, DOI: 10.1002/hep.22472

  5. Keap1 in adhesion complexes

    Cell Motility and the Cytoskeleton

    Volume 56, Issue 2, October 2003, Pages: 109–119, Michaella Velichkova and Tama Hasson

    Version of Record online : 14 AUG 2003, DOI: 10.1002/cm.10138

  6. You have free access to this content
    NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice


    Volume 59, Issue 6, June 2014, Pages: 2371–2382, Keiichi Shirasaki, Keiko Taguchi, Michiaki Unno, Hozumi Motohashi and Masayuki Yamamoto

    Version of Record online : 25 APR 2014, DOI: 10.1002/hep.27020

  7. You have free access to this content
    Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system

    Genes to Cells

    Volume 7, Issue 8, August 2002, Pages: 807–820, Makoto Kobayashi, Ken Itoh, Takafumi Suzuki, Hitoshi Osanai, Keizo Nishikawa, Yasutake Katoh, Yaeko Takagi and Masayuki Yamamoto

    Version of Record online : 7 AUG 2002, DOI: 10.1046/j.1365-2443.2002.00561.x

  8. Structural analysis of the complex of Keap1 with a prothymosin α peptide

    Acta Crystallographica Section F

    Volume 64, Issue 4, April 2008, Pages: 233–238, Balasundaram Padmanabhan, Yoshihiro Nakamura and Shigeyuki Yokoyama

    DOI: 10.1107/S1744309108004995

  9. Molecular mechanisms of natural products in chemoprevention: Induction of cytoprotective enzymes by Nrf2

    Molecular Nutrition & Food Research

    Volume 52, Issue S1, June 2008, Pages: S84–S94, Aimee L. Eggler, Kelly A. Gay and Andrew D. Mesecar

    Version of Record online : 25 APR 2008, DOI: 10.1002/mnfr.200700249

  10. You have full text access to this OnlineOpen article
    Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation

    FEBS Open Bio

    Volume 5, Issue 1, January 01, 2015, Pages: 557–570, Mikiya Satoh, Hajime Saburi, Tomoyuki Tanaka, Yoshinori Matsuura, Hisashi Naitow, Rieko Shimozono, Naoyoshi Yamamoto, Hideki Inoue, Noriko Nakamura, Yoshitaka Yoshizawa, Takumi Aoki, Ryuji Tanimura and Naoki Kunishima

    Version of Record online : 30 JUN 2015, DOI: 10.1016/j.fob.2015.06.011

  11. Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer

    Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling

    Masanobu Morita, Hozumi Motohashi, Pages: 63–82, 2011

    Published Online : 7 NOV 2011, DOI: 10.1002/9781118148143.ch5

  12. Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis


    Volume 62, Issue 3, September 2015, Pages: 851–862, Patrizia Zavattari, Andrea Perra, Silvia Menegon, Marta Anna Kowalik, Annalisa Petrelli, Maria Maddalena Angioni, Antonia Follenzi, Luca Quagliata, Giovanna Maria Ledda-Columbano, Luigi Terracciano, Silvia Giordano and Amedeo Columbano

    Version of Record online : 22 APR 2015, DOI: 10.1002/hep.27790

  13. Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1

    Journal of Biochemical and Molecular Toxicology

    Volume 25, Issue 5, September/October 2011, Pages: 320–329, Qiuqiong Cheng, Keiko Taguchi, Lauren M. Aleksunes, José E. Manautou, Nathan J. Cherrington, Masayuki Yamamoto and Angela L. Slitt

    Version of Record online : 2 MAY 2011, DOI: 10.1002/jbt.20392

  14. Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1

    Journal of Synchrotron Radiation

    Volume 15, Issue 3, May 2008, Pages: 273–276, Balasundaram Padmanabhan, Kit I. Tong, Akira Kobayashi, Masayuki Yamamoto and Shigeyuki Yokoyama

    DOI: 10.1107/S090904950705114X

  15. Activation of the Nrf2–ARE signaling pathway: a promising strategy in cancer prevention


    Volume 28, Issue 2, February 2006, Pages: 169–181, Aldo Giudice and Maurizio Montella

    Version of Record online : 24 JAN 2006, DOI: 10.1002/bies.20359

  16. You have free access to this content
    Identification and Characterization of Novel Nrf2 Inducers Designed to Target the Intervening Region of Keap1

    Chemical Biology & Drug Design

    Volume 75, Issue 5, May 2010, Pages: 475–480, Jian H. Wu, Weimin Miao, Liang G. Hu and Gerald Batist

    Version of Record online : 12 MAR 2010, DOI: 10.1111/j.1747-0285.2010.00955.x

  17. The Helicobacter Pylori Protein HspB Interferes With Nrf2/Keap1 Pathway Altering The Antioxidant Response of Ags Cells


    Volume 17, Issue 6, December 2012, Pages: 417–425, Elisabetta Buommino, Giovanna Donnarumma, Lucrezia Manente, Anna De Filippis, Francesco Silvestri, Salvatore Iaquinto, Maria Antonietta Tufano and Antonio De Luca

    Version of Record online : 11 JUL 2012, DOI: 10.1111/j.1523-5378.2012.00973.x

  18. You have free access to this content
    Nrf2 induces fibroblast growth factor 21 in diabetic mice

    Genes to Cells

    Volume 19, Issue 12, December 2014, Pages: 864–878, Yuki Furusawa, Akira Uruno, Yoko Yagishita, Chika Higashi and Masayuki Yamamoto

    Version of Record online : 1 OCT 2014, DOI: 10.1111/gtc.12186

  19. Arsenic-Mediated Activation of the Nrf2-Keap1 Antioxidant Pathway

    Journal of Biochemical and Molecular Toxicology

    Volume 27, Issue 2, February 2013, Pages: 99–105, Alexandria Lau, Samantha A. Whitman, Melba C. Jaramillo and Donna D. Zhang

    Version of Record online : 27 NOV 2012, DOI: 10.1002/jbt.21463

  20. Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer

    Head & Neck

    Volume 37, Issue 5, May 2015, Pages: 727–734, Victor D. Martinez, Emily A. Vucic, Kelsie L. Thu, Larissa A. Pikor, Stephen Lam and Wan L. Lam

    Version of Record online : 18 JUN 2014, DOI: 10.1002/hed.23663