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There are 22719 results for: content related to: EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

  1. You have free access to this content
    MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway

    The EMBO Journal

    Volume 28, Issue 13, July 8, 2009, Pages: 1926–1939, Francesca Mancini, Giusy Di Conza, Marsha Pellegrino, Cinzia Rinaldo, Andrea Prodosmo, Simona Giglio, Igea D'Agnano, Fulvio Florenzano, Lara Felicioni, Fiamma Buttitta, Antonio Marchetti, Ada Sacchi, Alfredo Pontecorvi, Silvia Soddu and Fabiola Moretti

    Version of Record online : 11 JUN 2009, DOI: 10.1038/emboj.2009.154

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    The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis

    The Journal of Pathology

    Volume 241, Issue 4, March 2017, Pages: 501–510, Shunbin Xiong, Vinod Pant, Yun Zhang, Neeraj K Aryal, M James You, Donna Kusewitt and Guillermina Lozano

    Version of Record online : 6 JAN 2017, DOI: 10.1002/path.4854

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    The Mdm Network and Its Regulation of p53 Activities: A Rheostat of Cancer Risk

    Human Mutation

    Volume 35, Issue 6, June 2014, Pages: 728–737, Christine M. Eischen and Guillermina Lozano

    Version of Record online : 6 MAR 2014, DOI: 10.1002/humu.22524

  4. You have full text access to this Open Access content
    S-MDM4 mRNA overexpression indicates a poor prognosis and marks a potential therapeutic target in chronic lymphocytic leukemia

    Cancer Science

    Volume 103, Issue 12, December 2012, Pages: 2056–2063, Ling Liu, Lei Fan, Cheng Fang, Zhi-Jian Zou, Shu Yang, Li-Na Zhang, Jian-Yong Li and Wei Xu

    Version of Record online : 10 OCT 2012, DOI: 10.1111/cas.12008

  5. MDM4 is a rational target for treating breast cancers with mutant p53

    The Journal of Pathology

    Volume 241, Issue 5, April 2017, Pages: 661–670, Panimaya Jeffreena Miranda, Daniel Buckley, Dinesh Raghu, Jia-Min B Pang, Elena A Takano, Reshma Vijayakumaran, Amina FAS Teunisse, Atara Posner, Tahlia Procter, Marco J Herold, Cristina Gamell, Jean-Christophe Marine, Stephen B Fox, Aart Jochemsen, Sue Haupt and Ygal Haupt

    Version of Record online : 1 MAR 2017, DOI: 10.1002/path.4877

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    MDM4 regulation by the let-7 miRNA family in the DNA damage response of glioma cells

    FEBS Letters

    Volume 589, Issue 15, July 08, 2015, Pages: 1958–1965, Chen Xie, Wei Chen, Mengdie Zhang, Qiuxian Cai, Weiyi Xu, Xiaodi Li and Songshan Jiang

    Version of Record online : 27 MAY 2015, DOI: 10.1016/j.febslet.2015.05.030

  7. Mouse double minute 4 variants modify susceptibility to risk of recurrence in patients with squamous cell carcinoma of the oropharynx

    Molecular Carcinogenesis

    Volume 57, Issue 3, March 2018, Pages: 361–369, Zhongming Lu, Erich M. Sturgis, Lijun Zhu, Hua Zhang, Ye Tao, Peng Wei, Qingyi Wei and Guojun Li

    Version of Record online : 13 NOV 2017, DOI: 10.1002/mc.22760

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    Modifying effect of MDM4 variants on risk of HPV16-associated squamous cell carcinoma of oropharynx


    Volume 118, Issue 6, 15 March 2012, Pages: 1684–1692, Hongping Yu, Erich M. Sturgis, Zhensheng Liu, Li-E. Wang, Qingyi Wei and Guojun Li

    Version of Record online : 5 AUG 2011, DOI: 10.1002/cncr.26423

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    Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target

    International Journal of Cancer

    Volume 104, Issue 6, 10 May 2003, Pages: 752–757, Markus J. Riemenschneider, Christiane B. Knobbe and Guido Reifenberger

    Version of Record online : 6 FEB 2003, DOI: 10.1002/ijc.11023

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    MDM4 binds ligands via a mechanism in which disordered regions become structured

    FEBS Letters

    Volume 584, Issue 14, July 16, 2010, Pages: 3035–3041, Maria C. Sanchez, Jonathan G. Renshaw, Gareth Davies, Paul N. Barlow and Martin Vogtherr

    Version of Record online : 31 MAY 2010, DOI: 10.1016/j.febslet.2010.05.058

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    TP53 pathway analysis in paediatric Burkitt lymphoma reveals increased MDM4 expression as the only TP53 pathway abnormality detected in a subset of cases

    British Journal of Haematology

    Volume 158, Issue 6, September 2012, Pages: 763–771, Vasiliki Leventaki, Vladimir Rodic, Sheryl R. Tripp, Michael G. Bayerl, Sherrie L. Perkins, Phillip Barnette, Joshua D. Schiffman and Rodney R. Miles

    Version of Record online : 27 JUL 2012, DOI: 10.1111/j.1365-2141.2012.09243.x

  12. You have full text access to this OnlineOpen article
    MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk

    Cancer Medicine

    Volume 4, Issue 12, December 2015, Pages: 1901–1907, Liv B. Gansmo, Pål Romundstad, Einar Birkeland, Kristian Hveem, Lars Vatten, Stian Knappskog and Per Eystein Lønning

    Version of Record online : 16 OCT 2015, DOI: 10.1002/cam4.555

  13. Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models

    The Journal of Pathology

    Volume 224, Issue 4, August 2011, Pages: 540–552, Tamara Terzian, Melissa Dumble, Farinaz Arbab, Christina Thaller, Lawrence A Donehower, Guillermina Lozano, Monica J Justice, Dennis R Roop and Neil F Box

    Version of Record online : 14 JUN 2011, DOI: 10.1002/path.2891

  14. Protein–Protein Interactions as Drug Discovery Targets

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Alexander Dömling

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc129

  15. Observation and modelling of main-sequence star chromospheres – XVIII. Observations of the Ca ii resonance lines and Hα line for dM4 stars and dK5 stars

    Monthly Notices of the Royal Astronomical Society

    Volume 421, Issue 4, April 2012, Pages: 3189–3205, E. R. Houdebine

    Version of Record online : 13 MAR 2012, DOI: 10.1111/j.1365-2966.2012.20649.x

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    Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility

    FEBS Letters

    Volume 590, Issue 16, August 2016, Pages: 2566–2574, Gabriel Livera, Rustem Uzbekov, Peggy Jarrier, Sophie Fouchécourt, Clotilde Duquenne, Anne-Simone Parent, Jean-Christophe Marine and Philippe Monget

    Version of Record online : 18 JUL 2016, DOI: 10.1002/1873-3468.12275

  17. Influence of MDM2 and MDM4 on development and survival in hereditary retinoblastoma

    Pediatric Blood & Cancer

    Volume 59, Issue 1, 15 July 2012, Pages: 39–43, Adriana Helena de Oliveira Reis, Ivna Néria Silva Ribamar de Carvalho, Paula Batista de Sousa Damasceno, Sima Esther Ferman, Evandro Lucena, Jorge Santiago Lopez-Camelo, Héctor N. Seuánez and Fernando Regla Vargas

    Version of Record online : 16 DEC 2011, DOI: 10.1002/pbc.24014

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    The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers

    The Journal of Pathology

    Volume 220, Issue 4, March 2010, Pages: 419–434, Tarek M Abdel-Fatah, Desmond G Powe, Johnson Agboola, Martyna Adamowicz-Brice, Roger W Blamey, Maria A Lopez-Garcia, Andrew R Green, Jorge S Reis-Filho and Ian O Ellis

    Version of Record online : 17 NOV 2009, DOI: 10.1002/path.2663

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    Etiology-dependent molecular mechanisms in human hepatocarcinogenesis


    Volume 47, Issue 2, February 2008, Pages: 511–520, Christof Schlaeger, Thomas Longerich, Claudia Schiller, Peter Bewerunge, Arianeb Mehrabi, Grischa Toedt, Jörg Kleeff, Volker Ehemann, Roland Eils, Peter Lichter, Peter Schirmacher and Bernhard Radlwimmer

    Version of Record online : 26 DEC 2007, DOI: 10.1002/hep.22033

  20. You have full text access to this Open Access content
    Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells

    Cancer Science

    Volume 102, Issue 3, March 2011, Pages: 605–613, Shinji Endo, Kenji Yamato, Sachiko Hirai, Toshikazu Moriwaki, Kuniaki Fukuda, Hideo Suzuki, Masato Abei, Ichiro Nakagawa and Ichinosuke Hyodo

    Version of Record online : 12 JAN 2011, DOI: 10.1111/j.1349-7006.2010.01821.x