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There are 21876 results for: content related to: Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: An explanation for high acetaminophen dosage in humans without hepatic injury

  1. You have free access to this content
    Activation of autophagy protects against acetaminophen-induced hepatotoxicity

    Hepatology

    Volume 55, Issue 1, January 2012, Pages: 222–232, Hong-Min Ni, Abigail Bockus, Nikki Boggess, Hartmut Jaeschke and Wen-Xing Ding

    Version of Record online : 6 DEC 2011, DOI: 10.1002/hep.24690

  2. SIMULTANEOUS MODELLING OF THE MICHAELIS-MENTEN KINETICS OF PARACETAMOL SULPHATION AND GLUCURONIDATION

    Clinical and Experimental Pharmacology and Physiology

    Volume 36, Issue 1, January 2009, Pages: 35–42, David Reith, Natalie J Medlicott, Rohana Kumara De Silva, Lin Yang, Jeremy Hickling and Mathew Zacharias

    Version of Record online : 28 AUG 2008, DOI: 10.1111/j.1440-1681.2008.05029.x

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    A Pharmacokinetic Comparison of Acetaminophen Products (Tylenol Extended Relief vs Regular Tylenol)

    Academic Emergency Medicine

    Volume 3, Issue 8, August 1996, Pages: 740–744, Daniel R. Douglas, James B. Sholal and Martin J. Smilkstein

    Version of Record online : 29 SEP 2008, DOI: 10.1111/j.1553-2712.1996.tb03508.x

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    Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice

    Hepatology

    Volume 54, Issue 6, December 2011, Pages: 2208–2217, Simrat P.S. Saini, Bin Zhang, Yongdong Niu, Mengxi Jiang, Jie Gao, Yonggong Zhai, Jung Hoon Lee, Hirdesh Uppal, Hui Tian, Michael A. Tortorici, Samuel M. Poloyac, Wenxin Qin, Raman Venkataramanan and Wen Xie

    Version of Record online : 30 NOV 2011, DOI: 10.1002/hep.24646

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    Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity

    Hepatology

    Volume 56, Issue 1, July 2012, Pages: 281–290, Andrew D. Patterson, Yatrik M. Shah, Tsutomu Matsubara, Kristopher W. Krausz and Frank J. Gonzalez

    Version of Record online : 6 JUN 2012, DOI: 10.1002/hep.25645

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    Farnesyltransferase inhibitors reduce ras activation and ameliorate acetaminophen-induced liver injury in mice

    Hepatology

    Volume 50, Issue 5, November 2009, Pages: 1547–1557, Banishree Saha and Dipankar Nandi

    Version of Record online : 20 JUL 2009, DOI: 10.1002/hep.23180

  7. Spontaneous chemiluminescence production, lipid peroxidation, and covalent binding in rat hepatocytes exposed to acetaminophen

    Journal of Pharmaceutical Sciences

    Volume 87, Issue 5, May 1998, Pages: 640–646, Yoshiyuki Minamide, Toshiharu Horiea, Atsuko Tomaru and Shoji Awazu

    Version of Record online : 12 JUN 2000, DOI: 10.1021/js9701014

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    Dendritic cell depletion exacerbates acetaminophen hepatotoxicity

    Hepatology

    Volume 54, Issue 3, 2 September 2011, Pages: 959–968, Michael K. Connolly, Diego Ayo, Ashim Malhotra, Michael Hackman, Andrea S. Bedrosian, Junaid Ibrahim, Napoleon E. Cieza-Rubio, Andrew H. Nguyen, Justin R. Henning, Monica Dorvil-Castro, H. Leon Pachter and George Miller

    Version of Record online : 8 AUG 2011, DOI: 10.1002/hep.24429

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    Echinomycin Decreases Induction of Vascular Endothelial Growth Factor and Hepatocyte Regeneration in Acetaminophen Toxicity in Mice

    Basic & Clinical Pharmacology & Toxicology

    Volume 110, Issue 4, April 2012, Pages: 327–334, Alessandra Milesi-Hallé, Sandra McCullough, Jack A. Hinson, Richard C. Kurten, Laura W. Lamps, Aliza Brown and Laura P. James

    Version of Record online : 9 NOV 2011, DOI: 10.1111/j.1742-7843.2011.00812.x

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    Targeting mitochondria with methylene blue protects mice against acetaminophen-induced liver injury

    Hepatology

    Volume 61, Issue 1, January 2015, Pages: 326–336, Kang Kwang Lee, Naoki Imaizumi, Sally R. Chamberland, Nathan N. Alder and Urs A. Boelsterli

    Version of Record online : 15 DEC 2014, DOI: 10.1002/hep.27385

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    Chronic intermittent hypoxia and acetaminophen induce synergistic liver injury in mice

    Experimental Physiology

    Volume 94, Issue 2, February 2009, Pages: 228–239, Vladimir Savransky, Christian Reinke, Jonathan Jun, Shannon Bevans-Fonti, Ashika Nanayakkara, Jianguo Li, Allen C. Myers, Michael S. Torbenson and Vsevolod Y. Polotsky

    Version of Record online : 15 JAN 2009, DOI: 10.1113/expphysiol.2008.044883

  12. Acetaminophen-Associated Hepatic Injury: Evaluation of Acetaminophen Protein Adducts in Children and Adolescents With Acetaminophen Overdose

    Clinical Pharmacology & Therapeutics

    Volume 84, Issue 6, December 2008, Pages: 684–690, LP James, EV Capparelli, PM Simpson, L Letzig, D Roberts, JA Hinson, GL Kearns, JL Blumer, JE Sullivan and The Network of Pediatric Pharmacology Research Units, National Institutes of Child Health and Human Development

    Version of Record online : 15 OCT 2008, DOI: 10.1038/clpt.2008.190

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    Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

    FEBS Open Bio

    Volume 4, Issue 1, January 01, 2014, Pages: 777–787, Kenji Takemoto, Etsuro Hatano, Keiko Iwaisako, Masatoshi Takeiri, Naruto Noma, Saori Ohmae, Kan Toriguchi, Kazutaka Tanabe, Hirokazu Tanaka, Satoru Seo, Kojiro Taura, Keigo Machida, Norihiko Takeda, Shigehira Saji, Shinji Uemoto and Masataka Asagiri

    Version of Record online : 6 SEP 2014, DOI: 10.1016/j.fob.2014.08.007

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    Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity

    Hepatology

    Volume 54, Issue 4, October 2011, Pages: 1322–1332, Munzir M.E. Ahmed, Tao Wang, Yu Luo, Shuilong Ye, Qiao Wu, Zongsheng Guo, Bill D. Roebuck, Thomas R. Sutter and James Y. Yang

    Version of Record online : 6 SEP 2011, DOI: 10.1002/hep.24493

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    Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

    Hepatology

    Volume 58, Issue 6, December 2013, Pages: 2099–2108, Anup Ramachandran, Mitchell R. McGill, Yuchao Xie, Hong-Min Ni, Wen-Xing Ding and Hartmut Jaeschke

    Version of Record online : 11 OCT 2013, DOI: 10.1002/hep.26547

  16. Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress

    Journal of Pharmacy and Pharmacology

    Volume 67, Issue 7, July 2015, Pages: 980–989, Xuelin Zhou, Ching Mei Cheung, Jia-ming Yang, Penelope M.Y. Or, Wayne Y.W. Lee and John H.K. Yeung

    Version of Record online : 2 FEB 2015, DOI: 10.1111/jphp.12381

  17. Enhanced Physical Stability of Amorphous Drug Formulations via Dry Polymer Coating

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 6, June 2015, Pages: 2076–2084, Maxx Capece and Rajesh Davé

    Version of Record online : 22 APR 2015, DOI: 10.1002/jps.24451

  18. Prescription-acquired acetaminophen use and potential overuse patterns: 2001–2008

    Pharmacoepidemiology and Drug Safety

    Volume 21, Issue 2, February 2012, Pages: 226–230, Mugdha Gokhale and Bradley C. Martin

    Version of Record online : 13 SEP 2011, DOI: 10.1002/pds.2235

  19. Two-year outcomes in initial survivors with acute liver failure: results from a prospective, multicentre study

    Liver International

    Volume 35, Issue 2, February 2015, Pages: 370–380, Robert J. Fontana, Caitlyn Ellerbe, Valerie E. Durkalski, Amol Rangnekar, Rajender K. Reddy, Todd Stravitz, Brendan McGuire, Timothy Davern, Adrian Reuben, Iris Liou, Oren Fix, Daniel R. Ganger, Raymond T. Chung, Mike Schilsky, Steven Han, Linda S. Hynan, Corron Sanders, William M. Lee and forthe US Acute Liver Failure Study Group

    Version of Record online : 28 JUL 2014, DOI: 10.1111/liv.12632

  20. Acetaminophen Metabolism After Major Surgery: A Greater Challenge With Increasing Age

    Clinical Pharmacology & Therapeutics

    Volume 90, Issue 5, November 2011, Pages: 707–711, G Pickering, E Schneider, I Papet, E Pujos-Guillot, B Pereira, E Simen, C Dubray and P Schoeffler

    Version of Record online : 5 OCT 2011, DOI: 10.1038/clpt.2011.176