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There are 5409 results for: content related to: Functional characterization of splicing and ligand-binding domain variants in the LDL receptor

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    The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR

    Traffic

    Volume 8, Issue 6, June 2007, Pages: 718–732, Nasha Nassoury, Daniel A. Blasiole, Angie Tebon Oler, Suzanne Benjannet, Josée Hamelin, Vivianne Poupon, Peter S. McPherson, Alan D. Attie, Annik Prat and Nabil G. Seidah

    Version of Record online : 25 APR 2007, DOI: 10.1111/j.1600-0854.2007.00562.x

  2. You have full text access to this OnlineOpen article
    Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum

    FEBS Open Bio

    Volume 4, Issue 1, January 01, 2014, Pages: 321–327, Thea Bismo Strøm, Kristian Tveten, Jon K. Laerdahl and Trond P. Leren

    Version of Record online : 19 MAR 2014, DOI: 10.1016/j.fob.2014.03.007

  3. Functional Characterization and Classification of Frequent Low-Density Lipoprotein Receptor Variants

    Human Mutation

    Volume 36, Issue 1, January 2015, Pages: 129–141, Aitor Etxebarria, Asier Benito-Vicente, Lourdes Palacios, Marianne Stef, Ana Cenarro, Fernando Civeira, Helena Ostolaza and Cesar Martin

    Version of Record online : 27 NOV 2014, DOI: 10.1002/humu.22721

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    Low-Density Lipoprotein Receptor Gene Familial Hypercholesterolemia Variant Database: Update and Pathological Assessment

    Annals of Human Genetics

    Volume 76, Issue 5, September 2012, Pages: 387–401, Ebele Usifo, Sarah E. A. Leigh, Ros A. Whittall, Nicholas Lench, Alison Taylor, Corin Yeats, Christine A. Orengo, Andrew C. R. Martin, Jacopo Celli and Steve E. Humphries

    Version of Record online : 10 AUG 2012, DOI: 10.1111/j.1469-1809.2012.00724.x

  5. You have full text access to this OnlineOpen article
    β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cells

    The FEBS Journal

    Volume 282, Issue 14, July 2015, Pages: 2682–2696, Amanda E. Starr, Valérie Lemieux, Jenny Noad, Jasmine I. Moore, Thilina Dewpura, Angela Raymond, Michel Chrétien, Daniel Figeys and Janice Mayne

    Version of Record online : 18 MAY 2015, DOI: 10.1111/febs.13309

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    Novel LDLR Variants in Patients with Familial Hypercholesterolemia: In Silico Analysis as a Tool to Predict Pathogenic Variants in Children and Their Families

    Annals of Human Genetics

    Volume 77, Issue 5, September 2013, Pages: 426–434, Vasiliki Mollaki, Pavlos Progias and Euridiki Drogari

    Version of Record online : 2 JUL 2013, DOI: 10.1111/ahg.12032

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    Role of low-density lipoprotein receptor in the hepatitis C virus life cycle

    Hepatology

    Volume 55, Issue 4, April 2012, Pages: 998–1007, Anna Albecka, Sandrine Belouzard, Anne Op de Beeck, Véronique Descamps, Lucie Goueslain, Justine Bertrand-Michel, François Tercé, Gilles Duverlie, Yves Rouillé and Jean Dubuisson

    Version of Record online : 27 MAR 2012, DOI: 10.1002/hep.25501

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    Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR

    The EMBO Journal

    Volume 26, Issue 14, July 25, 2007, Pages: 3273–3282, Peter Michaely, Zhenze Zhao, Wei-Ping Li, Rita Garuti, Lily J Huang, Helen H Hobbs and Jonathan C Cohen

    Version of Record online : 21 JUN 2007, DOI: 10.1038/sj.emboj.7601769

  9. You have full text access to this OnlineOpen article
    Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia

    Arthritis & Rheumatism

    Volume 64, Issue 8, August 2012, Pages: 2707–2718, Myles J. Lewis, Talat H. Malik, Liliane Fossati-Jimack, Daniele Carassiti, H. Terence Cook, Dorian O. Haskard and Marina Botto

    Version of Record online : 27 JUL 2012, DOI: 10.1002/art.34451

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    Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes

    British Journal of Pharmacology

    Volume 172, Issue 5, March 2015, Pages: 1379–1394, F Cerrato, M E Fernández-Suárez, R Alonso, M Alonso, C Vázquez, O Pastor, P Mata, M A Lasunción and D Gómez-Coronado

    Version of Record online : 8 JAN 2015, DOI: 10.1111/bph.13016

  11. Functional analysis of LDLR promoter and 5′ UTR mutations in subjects with clinical diagnosis of familial hypercholesterolemia

    Human Mutation

    Volume 32, Issue 8, August 2011, Pages: 868–872, Isabel De Castro-Orós, Sandra Pampín, Alfonso Bolado-Carrancio, Aguirre De Cubas, Lourdes Palacios, Nuria Plana, Jose Puzo, Esperanza Martorell, Marianne Stef, Luis Masana, Fernando Civeira, Jose Carlos Rodríguez-Rey and Miguel Pocoví

    Version of Record online : 12 JUL 2011, DOI: 10.1002/humu.21520

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    Identification of human low-density lipoprotein receptor as a novel target gene regulated by liver X receptor alpha

    FEBS Letters

    Volume 580, Issue 20, September 04, 2006, Pages: 4929–4933, Kenji Ishimoto, Keisuke Tachibana, Mikako Sumitomo, Shiho Omote, Ikuko Hanano, Daisuke Yamasaki, Yuichiro Watanabe, Toshiya Tanaka, Takao Hamakubo, Juro Sakai, Tatsuhiko Kodama and Takefumi Doi

    Version of Record online : 14 AUG 2006, DOI: 10.1016/j.febslet.2006.08.010

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    MMP-2 inhibits PCSK9-induced degradation of the LDL receptor in Hepa1-c1c7 cells

    FEBS Letters

    Volume 589, Issue 4, February 13, 2015, Pages: 490–496, Xiang Wang, Evan Berry, Samuel Hernandez-Anzaldo, Difei Sun, Ayinuer Adijiang, Liang Li, Dawei Zhang and Carlos Fernandez-Patron

    Version of Record online : 19 JAN 2015, DOI: 10.1016/j.febslet.2015.01.007

  14. Proprotein Convertases Subtilisin/Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶—枯草溶菌素/蛋白酶K,一种酶转变的护送蛋白:在肝脏与肝外的功能)

    Journal of Diabetes

    Volume 5, Issue 4, December 2013, Pages: 391–405, Majambu Mbikay, Janice Mayne and Michel Chrétien

    Version of Record online : 8 JUL 2013, DOI: 10.1111/1753-0407.12064

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    PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression

    Hepatology

    Volume 50, Issue 1, July 2009, Pages: 17–24, Patrick Labonté, Syntia Begley, Carl Guévin, Marie-Claude Asselin, Nasha Nassoury, Gaétan Mayer, Annik Prat and Nabil G. Seidah

    Version of Record online : 18 FEB 2009, DOI: 10.1002/hep.22911

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    The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome

    FEBS Letters

    Volume 589, Issue 23, November 30, 2015, Pages: 3534–3540, Juan Martínez-Oliván, Xabier Arias-Moreno, Ramón Hurtado-Guerrero, José Alberto Carrodeguas, Laura Miguel-Romero, Alberto Marina, Pierpaolo Bruscolini and Javier Sancho

    Version of Record online : 23 OCT 2015, DOI: 10.1016/j.febslet.2015.10.014

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    Mutation detection in Croatian patients with Familial Hypercholesterolemia

    Annals of Human Genetics

    Volume 77, Issue 1, January 2013, Pages: 22–30, Ivan Pećin, Ros Whittall, Marta Futema, Jadranka Sertić, Željko Reiner, Sarah E. A. Leigh and Steve E. Humphries

    Version of Record online : 6 NOV 2012, DOI: 10.1111/j.1469-1809.2012.00735.x

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    Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant

    Journal of Neurochemistry

    Volume 115, Issue 3, November 2010, Pages: 614–624, I-Fang Ling, Rangaraj K. Gopalraj, James F. Simpson and Steven Estus

    Version of Record online : 28 SEP 2010, DOI: 10.1111/j.1471-4159.2010.06972.x

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    Update and Analysis of the University College London Low Density Lipoprotein Receptor Familial Hypercholesterolemia Database

    Annals of Human Genetics

    Volume 72, Issue 4, July 2008, Pages: 485–498, S. E. A. Leigh, A. H. Foster, R. A. Whittall, C. S. Hubbart and S. E. Humphries

    Version of Record online : 5 MAR 2008, DOI: 10.1111/j.1469-1809.2008.00436.x

  20. Atorvastatin increases expression of low-density lipoprotein receptor mRNA in human circulating mononuclear cells

    Clinical and Experimental Pharmacology and Physiology

    Volume 37, Issue 4, April 2010, Pages: 471–476, Anothai Pocathikorn, Roger R Taylor and Cyril DS Mamotte

    Version of Record online : 23 NOV 2009, DOI: 10.1111/j.1440-1681.2009.05337.x