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There are 2199 results for: content related to: Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe

  1. You have free access to this content
    Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein

    Journal of Neurochemistry

    Volume 122, Issue 3, August 2012, Pages: 650–658, Jingwen Niu, Mei Yu, Chunyan Wang and Zhiheng Xu

    Version of Record online : 22 JUN 2012, DOI: 10.1111/j.1471-4159.2012.07809.x

  2. You have full text access to this OnlineOpen article
    Novel recruitment strategy to enrich for LRRK2 mutation carriers

    Molecular Genetics & Genomic Medicine

    Volume 3, Issue 5, September 2015, Pages: 404–412, Tatiana Foroud, Danielle Smith, Jacqueline Jackson, Jennifer Verbrugge, Cheryl Halter, Leah Wetherill, Katherine Sims, Winnie Xin, Vanessa Arnedo, Shirley Lasch, Kenneth Marek and the Parkinson's Progression Markers Initiative

    Version of Record online : 6 MAY 2015, DOI: 10.1002/mgg3.151

  3. LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease

    Movement Disorders

    Volume 25, Issue 15, 15 November 2010, Pages: 2536–2541, Rachel Saunders-Pullman, Matthew J. Barrett, Kaili M. Stanley, Marta San Luciano, Vicki Shanker, Lawrence Severt, Ann Hunt, Deborah Raymond, Laurie J. Ozelius and Susan B. Bressman

    Version of Record online : 3 SEP 2010, DOI: 10.1002/mds.23314

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    LRRK2 in Parkinson’s disease: in vivo models and approaches for understanding pathogenic roles

    The FEBS Journal

    Volume 276, Issue 22, November 2009, Pages: 6445–6454, Zhenyu Yue

    Version of Record online : 5 OCT 2009, DOI: 10.1111/j.1742-4658.2009.07343.x

  5. You have full text access to this OnlineOpen article
    Ten Years and Counting: Moving Leucine-Rich RepeatKinase 2 Inhibitors to the Clinic

    Movement Disorders

    Volume 30, Issue 2, February 2015, Pages: 180–189, Andrew B. West

    Version of Record online : 1 DEC 2014, DOI: 10.1002/mds.26075

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    Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER–Golgi export

    The EMBO Journal

    Volume 33, Issue 20, 16 October 2014, Pages: 2314–2331, Hyun Jin Cho, Jia Yu, Chengsong Xie, Parvathi Rudrabhatla, Xi Chen, Junbing Wu, Loukia Parisiadou, Guoxiang Liu, Lixin Sun, Bo Ma, Jinhui Ding, Zhihua Liu and Huaibin Cai

    Version of Record online : 8 SEP 2014, DOI: 10.15252/embj.201487807

  7. Disclosure of research results in genetic studies of Parkinson's disease caused by LRRK2 mutations

    Movement Disorders

    Volume 30, Issue 7, June 2015, Pages: 904–908, Claustre Pont-Sunyer, Susan Bressman, Deborah Raymond, Amanda Glickman, Eduardo Tolosa and Rachel Saunders-Pullman

    Version of Record online : 7 MAY 2015, DOI: 10.1002/mds.26250

  8. Cognitive profile of LRRK2-related Parkinson's disease

    Movement Disorders

    Volume 30, Issue 5, 15 April 2015, Pages: 728–733, Sindhu Srivatsal, Brenna Cholerton, James B. Leverenz, Zbigniew K. Wszolek, Ryan J. Uitti, Dennis W. Dickson, Daniel Weintraub, John Q. Trojanowski, Vivianna M. Van Deerlin, Joseph F. Quinn, Kathryn A. Chung, Amie L. Peterson, Stewart A. Factor, Cathy Wood-Siverio, Jennifer G. Goldman, Glenn T. Stebbins, Bryan Bernard, Beate Ritz, Rebecca Rausch, Alberto J. Espay, Fredy J. Revilla, Johnna Devoto, Liana S. Rosenthal, Ted M. Dawson, Marilyn S. Albert, Ignacio F. Mata, Shu-Ching Hu, Kathleen S. Montine, Catherine Johnson, Thomas J. Montine, Karen L. Edwards, Jing Zhang and Cyrus P. Zabetian

    Version of Record online : 4 FEB 2015, DOI: 10.1002/mds.26161

  9. Leucine-rich repeat kinase 2 and alternative splicing in Parkinson's disease

    Movement Disorders

    Volume 27, Issue 8, July 2012, Pages: 1004–1011, David A. Elliott, Woojin S. Kim, Sarsha Gorissen, Glenda M. Halliday and John B.J. Kwok

    Version of Record online : 23 APR 2012, DOI: 10.1002/mds.25005

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    Poster Presentations

    Movement Disorders

    Volume 27, Issue S1, June 2012, Pages: S1–S523,

    Version of Record online : 19 JUN 2012, DOI: 10.1002/mds.25051

  11. Low-variance RNAs identify Parkinson's disease molecular signature in blood

    Movement Disorders

    Volume 30, Issue 6, May 2015, Pages: 813–821, Maria D. Chikina, Christophe P. Gerald, Xianting Li, Yongchao Ge, Hanna Pincas, Venugopalan D. Nair, Aaron K. Wong, Arjun Krishnan, Olga G. Troyanskaya, Deborah Raymond, Rachel Saunders-Pullman, Susan B. Bressman, Zhenyu Yue and Stuart C. Sealfon

    Version of Record online : 18 MAR 2015, DOI: 10.1002/mds.26205

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    Cellular processes associated with LRRK2 function and dysfunction

    The FEBS Journal

    Volume 282, Issue 15, August 2015, Pages: 2806–2826, Rebecca Wallings, Claudia Manzoni and Rina Bandopadhyay

    Version of Record online : 9 MAY 2015, DOI: 10.1111/febs.13305

  13. Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)

    Human Mutation

    Volume 35, Issue 4, April 2014, Pages: 395–412, Ryan D. Mills, Terrence D. Mulhern, Fei Liu, Janetta G. Culvenor and Heung-Chin Cheng

    Version of Record online : 24 FEB 2014, DOI: 10.1002/humu.22515

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    Poster Presentations

    Movement Disorders

    Volume 30, Issue S1, June 2015, Pages: S1–S567,

    Version of Record online : 12 JUN 2015, DOI: 10.1002/mds.26295

  15. LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease

    Movement Disorders

    Volume 24, Issue 7, 15 May 2009, Pages: 1034–1041, Cyrus P. Zabetian, Mitsutoshi Yamamoto, Alexis N. Lopez, Hiroshi Ujike, Ignacio F. Mata, Yuishin Izumi, Ryuji Kaji, Hirofumi Maruyama, Hiroyuki Morino, Masaya Oda, Carolyn M. Hutter, Karen L. Edwards, Gerard D. Schellenberg, Debby W. Tsuang, Dora Yearout, Eric B. Larson and Hideshi Kawakami

    Version of Record online : 2 APR 2009, DOI: 10.1002/mds.22514

  16. Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutations

    Movement Disorders

    Volume 28, Issue 14, December 2013, Pages: 1966–1971, Roy N. Alcalay, Anat Mirelman, Rachel Saunders-Pullman, Ming-X Tang, Helen Mejia Santana, Deborah Raymond, Ernest Roos, Martha Orbe-Reilly, Tanya Gurevich, Anat Bar Shira, Mali Gana Weisz, Kira Yasinovsky, Maayan Zalis, Avner Thaler, Andres Deik, Matthew James Barrett, Jose Cabassa, Mark Groves, Ann L. Hunt, Naomi Lubarr, Marta San Luciano, Joan Miravite, Christina Palmese, Rivka Sachdev, Harini Sarva, Lawrence Severt, Vicki Shanker, Matthew Carrington Swan, Jeannie Soto-Valencia, Brooke Johannes, Robert Ortega, Stanley Fahn, Lucien Cote, Cheryl Waters, Pietro Mazzoni, Blair Ford, Elan Louis, Oren Levy, Llency Rosado, Diana Ruiz, Tsvyatko Dorovski, Michael Pauciulo, William Nichols, Avi Orr-Urtreger, Laurie Ozelius, Lorraine Clark, Nir Giladi, Susan Bressman and Karen S. Marder

    Version of Record online : 15 OCT 2013, DOI: 10.1002/mds.25647

  17. The neuropathology of genetic Parkinson's disease

    Movement Disorders

    Volume 27, Issue 7, June 2012, Pages: 831–842, Markos Poulopoulos, Oren A. Levy and Roy N. Alcalay

    Version of Record online : 26 MAR 2012, DOI: 10.1002/mds.24962

  18. Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death

    Human Mutation

    Volume 32, Issue 12, December 2011, Pages: 1390–1397, Dario C. Angeles, Bong-Hwa Gan, Luisa Onstead, Yi Zhao, Kah-Leong Lim, Justus Dachsel, Heather Melrose, Matt Farrer, Zbigniew K. Wszolek, Dennis W. Dickson and Eng-King Tan

    Version of Record online : 12 SEP 2011, DOI: 10.1002/humu.21582

  19. Clinical expression of LRRK2 G2019S mutations in the elderly

    Movement Disorders

    Volume 25, Issue 15, 15 November 2010, Pages: 2571–2576, Marta San Luciano, Richard B. Lipton, Cuiling Wang, Mindy Katz, Molly E. Zimmerman, Amy E. Sanders, Laurie J. Ozelius, Susan B. Bressman and Rachel Saunders-Pullman

    Version of Record online : 18 AUG 2010, DOI: 10.1002/mds.23330

  20. Motor and nonmotor heterogeneity of LRRK2-related and idiopathic Parkinson's disease

    Movement Disorders

    Connie Marras, Roy N. Alcalay, Chelsea Caspell-Garcia, Christopher Coffey, Piu Chan, John E. Duda, Maurizio F. Facheris, Rubén Fernández-Santiago, Javier Ruíz-Martínez, Tiago Mestre, Rachel Saunders-Pullman, Claustre Pont-Sunyer, Eduardo Tolosa, Bjorg Waro and the LRRK2 Cohort Consortium

    Version of Record online : 19 APR 2016, DOI: 10.1002/mds.26614