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There are 4143 results for: content related to: Cancer Risks for MLH 1 and MSH 2 Mutation Carriers

  1. A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

    Human Mutation

    Volume 34, Issue 1, January 2013, Pages: 200–209, Bryony A. Thompson, David E. Goldgar, Carol Paterson, Mark Clendenning, Rhiannon Walters, Sven Arnold, Michael T. Parsons, Walsh Michael D., Steven Gallinger, Robert W. Haile, John L. Hopper, Mark A. Jenkins, Loic LeMarchand, Noralane M. Lindor, Polly A. Newcomb, Stephen N. Thibodeau, Colon Cancer Family Registry, Joanne P. Young, Daniel D. Buchanan, Sean V. Tavtigian and Amanda B. Spurdle

    Version of Record online : 11 OCT 2012, DOI: 10.1002/humu.22213

  2. Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining

    The Journal of Pathology

    Volume 207, Issue 4, December 2005, Pages: 385–395, Elisabeth Mangold, Constanze Pagenstecher, Waltraut Friedl, Hans-Peter Fischer, Sabine Merkelbach-Bruse, Maike Ohlendorf, Nicolaus Friedrichs, Stefan Aretz, Reinhard Buettner, Peter Propping and Micaela Mathiak

    Version of Record online : 10 OCT 2005, DOI: 10.1002/path.1858

  3. You have full text access to this OnlineOpen article
    Lynch Syndrome Associated with Two MLH1 Promoter Variants and Allelic Imbalance of MLH1 Expression

    Human Mutation

    Volume 36, Issue 6, June 2015, Pages: 622–630, Luke B. Hesson, Deborah Packham, Chau-To Kwok, Andrea C. Nunez, Benedict Ng, Christa Schmidt, Michael Fields, Jason W.H. Wong, Mathew A. Sloane and Robyn L. Ward

    Version of Record online : 17 APR 2015, DOI: 10.1002/humu.22785

  4. Genetic Testing for Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

    Unit

    Current Protocols in Human Genetics

    10:10.12.1–10.12.28

    Madhuri R. Hegde and Benjamin B. Roa

    Published Online : 1 APR 2009, DOI: 10.1002/0471142905.hg1012s61

  5. Germ line MLH1 and MSH2 mutations in Taiwanese Lynch syndrome families: characterization of a founder genomic mutation in the MLH1 gene

    Clinical Genetics

    Volume 75, Issue 4, April 2009, Pages: 334–345, R Tang, C Hsiung, J-Y Wang, C-H Lai, H-T Chien, L-L Chiu, C-T Liu, H-H Chen, H-M Wang, S-X Chen, L-L Hsieh and the TCOG HNPCC Consortium

    Version of Record online : 15 APR 2009, DOI: 10.1111/j.1399-0004.2009.01162.x

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    Analysis of telomere dynamics in peripheral blood cells from patients with Lynch syndrome

    Cancer

    Volume 117, Issue 18, 15 September 2011, Pages: 4325–4335, Cristina Bozzao, Patrizia Lastella, Maurizio Ponz de Leon, Monica Pedroni, Carmela Di Gregorio, Francesco D. D'Ovidio, Nicoletta Resta, Fernando Prete, Ginevra Guanti and Alessandro Stella

    Version of Record online : 8 MAR 2011, DOI: 10.1002/cncr.26022

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    Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas

    International Journal of Cancer

    Volume 120, Issue 9, 1 May 2007, Pages: 1922–1929, Andrew Kaz, Young-Ho Kim, Slavomir Dzieciatkowski, Henry Lynch, Patrice Watson, Mary Kay Washington, Li Lin and William M. Grady

    Version of Record online : 2 FEB 2007, DOI: 10.1002/ijc.22544

  8. You have free access to this content
    Characterization of components of the mismatch repair machinery in Trypanosoma brucei

    Molecular Microbiology

    Volume 51, Issue 1, January 2004, Pages: 159–173, Joanna S. Bell, Timothy I. Harvey, Anne-Marie Sims and Richard McCulloch

    Version of Record online : 11 NOV 2003, DOI: 10.1046/j.1365-2958.2003.03804.x

  9. Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome

    Genes, Chromosomes and Cancer

    Volume 48, Issue 8, August 2009, Pages: 737–744, Renée C. Niessen, Robert M. W. Hofstra, Helga Westers, Marjolijn J. L. Ligtenberg, Krista Kooi, Paul O. J. Jager, Marloes L. de Groote, Trijnie Dijkhuizen, Maran J. W. Olderode-Berends, Harry Hollema, Jan H. Kleibeuker and Rolf H. Sijmons

    Version of Record online : 19 MAY 2009, DOI: 10.1002/gcc.20678

  10. Evidence of constitutional MLH1 epimutation associated to transgenerational inheritance of cancer susceptibility

    Human Mutation

    Volume 33, Issue 1, January 2012, Pages: 180–188, Michel Crépin, Marie-Claire Dieu, Sophie Lejeune, Fabienne Escande, Denis Boidin, Nicole Porchet, Gilles Morin, Sylvie Manouvrier, Michèle Mathieu and Marie-Pierre Buisine

    Version of Record online : 31 OCT 2011, DOI: 10.1002/humu.21617

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    Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain

    International Journal of Cancer

    Volume 98, Issue 5, 10 April 2002, Pages: 774–779, Trinidad Caldes, Javier Godino, Miguel de la Hoya, Iciar Garcia Carbonero, Pedro Perez Segura, Charis Eng, Manuel Benito and Eduardo Diaz-Rubio

    Version of Record online : 31 JAN 2002, DOI: 10.1002/ijc.10240

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    Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice

    International Journal of Cancer

    Volume 115, Issue 4, 1 July 2005, Pages: 666–669, Omar Kabbarah, Andrea K. Sotelo, Mary Ann Mallon, Erin L. Winkeler, Ming-Yu Fan, John D. Pfeifer, Darryl Shibata, David H. Gutmann and Paul J. Goodfellow

    Version of Record online : 7 FEB 2005, DOI: 10.1002/ijc.20918

  13. Clinical and molecular characteristics of hereditary non-polyposis colorectal cancer families in Southeast Asia

    Clinical Genetics

    Volume 68, Issue 2, August 2005, Pages: 137–145, S-C Lee, J-Y Guo, R Lim, R Soo, E Koay, M Salto-Tellez, A Leong and B-C Goh

    Version of Record online : 23 MAY 2005, DOI: 10.1111/j.1399-0004.2005.00469.x

  14. Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study)

    Clinical Genetics

    Volume 69, Issue 1, January 2006, Pages: 40–47, G Kurzawski, J Suchy, M Lener, E Kłujszo-Grabowska, J Kładny, K Safranow, K Jakubowska, A Jakubowska, T Huzarski, T Byrski, T Dębniak, C Cybulski, J Gronwald, O Oszurek, D Oszutowska, E Kowalska, S Góźdź, S Niepsuj, R Słomski, A Pławski, A Łącka-Wojciechowska, A Rozmiarek, Ł Fiszer-Maliszewska, M Bębenek, D Sorokin, MM Sąsiadek, A Stembalska, Z Grzebieniak, E Kilar, M Stawicka, D Godlewski, P Richter, I Brożek, B Wysocka, J Limon, A Jawień, Z Banaszkiewicz, H Janiszewska, J Kowalczyk, D Czudowska, RJ Scott and J Lubiński

    Version of Record online : 13 DEC 2005, DOI: 10.1111/j.1399-0004.2006.00550.x

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    Large genomic rearrangements and germline epimutations in Lynch syndrome

    International Journal of Cancer

    Volume 124, Issue 10, 15 May 2009, Pages: 2333–2340, Annette Gylling, Maaret Ridanpää, Outi Vierimaa, Kristiina Aittomäki, Kristiina Avela, Helena Kääriäinen, Hannele Laivuori, Minna Pöyhönen, Satu-Leena Sallinen, Carina Wallgren-Pettersson, Heikki J. Järvinen, Jukka-Pekka Mecklin and Paivi Peltomäki

    Version of Record online : 18 DEC 2008, DOI: 10.1002/ijc.24230

  16. You have full text access to this OnlineOpen article
    Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants

    Human Mutation

    Volume 32, Issue 1, January 2011, Pages: 107–115, Minttu Kansikas, Reetta Kariola and Minna Nyström

    Version of Record online : 22 DEC 2010, DOI: 10.1002/humu.21409

  17. You have free access to this content
    Evidence for breast cancer as an integral part of lynch syndrome

    Genes, Chromosomes and Cancer

    Volume 51, Issue 1, January 2012, Pages: 83–91, Nicole Buerki, Lucienne Gautier, Michal Kovac, Giancarlo Marra, Mauro Buser, Hansjakob Mueller and Karl Heinimann

    Version of Record online : 27 OCT 2011, DOI: 10.1002/gcc.20935

  18. You have free access to this content
    Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: A population-based study in northern Sweden

    International Journal of Cancer

    Volume 109, Issue 3, 10 April 2004, Pages: 370–376, Kristina Cederquist, Monica Emanuelsson, Ingela Göransson, Elke Holinski-Feder, Yvonne Müller-Koch, Irina Golovleva and Henrik Grönberg

    Version of Record online : 9 JAN 2004, DOI: 10.1002/ijc.11718

  19. Understanding the Pathogenicity of Noncoding Mismatch Repair Gene Promoter Variants in Lynch Syndrome

    Human Mutation

    Volume 37, Issue 5, May 2016, Pages: 417–426, Qing Liu, Bryony A. Thompson, Robyn L. Ward, Luke B. Hesson and Mathew A. Sloane

    Version of Record online : 18 MAR 2016, DOI: 10.1002/humu.22971

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    Combined analysis of three lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers

    International Journal of Cancer

    Volume 132, Issue 7, 1 April 2013, Pages: 1556–1564, Bente A. Talseth-Palmer, Juul T. Wijnen, Ingvild S. Brenne, Shantie Jagmohan-Changur, Daniel Barker, Katie A. Ashton, Carli M. Tops, Tiffany-Jane Evans, Mary McPhillips, Claire Groombridge, Janina Suchy, Grzegorz Kurzawski, The Dutch Cancer Genetics Group, Allan Spigelman, Pål Møller, Hans M. Morreau, Tom Van Wezel, Jan Lubinski, Hans F.A. Vasen and Rodney J. Scott

    Version of Record online : 11 OCT 2012, DOI: 10.1002/ijc.27843