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There are 7023177 results for: content related to: Whole gene deletion and splicing mutations expand the PINK1 genotypic spectrum

  1. You have full text access to this OnlineOpen article
    PINK1 function in health and disease

    EMBO Molecular Medicine

    Volume 1, Issue 3, June 2009, Pages: 152–165, Emma Deas, Helene Plun-Favreau and Nicholas W. Wood

    Version of Record online : 12 JUN 2009, DOI: 10.1002/emmm.200900024

  2. Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1)

    Human Mutation

    Volume 33, Issue 10, October 2012, Pages: 1408–1422, Chou Hung Sim, Kipros Gabriel, Ryan D. Mills, Janetta G. Culvenor and Heung-Chin Cheng

    Version of Record online : 5 JUL 2012, DOI: 10.1002/humu.22127

  3. PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation

    Journal of Neuroscience Research

    Volume 93, Issue 5, May 2015, Pages: 722–735, Boram Min, Young-Chang Kwon, Kwang-Min Choe and Kwang Chul Chung

    Version of Record online : 29 DEC 2014, DOI: 10.1002/jnr.23535

  4. Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function

    European Journal of Neuroscience

    Volume 31, Issue 4, February 2010, Pages: 623–633, Yanwei Xi, Joel Ryan, Sandra Noble, Man Yu, Ayse E. Yilbas and Marc Ekker

    Version of Record online : 5 FEB 2010, DOI: 10.1111/j.1460-9568.2010.07091.x

  5. You have free access to this content
    Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)

    Journal of Neurochemistry

    Volume 105, Issue 1, April 2008, Pages: 18–33, Ryan D. Mills, Chou Hung Sim, Su San Mok, Terrence D. Mulhern, Janetta G. Culvenor and Heung-Chin Cheng

    Version of Record online : 22 JAN 2008, DOI: 10.1111/j.1471-4159.2008.05249.x

  6. You have full text access to this OnlineOpen article
    Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

    The EMBO Journal

    Volume 34, Issue 22, 12 November 2015, Pages: 2840–2861, Yu-Chiang Lai, Chandana Kondapalli, Ronny Lehneck, James B Procter, Brian D Dill, Helen I Woodroof, Robert Gourlay, Mark Peggie, Thomas J Macartney, Olga Corti, Jean-Christophe Corvol, David G Campbell, Aymelt Itzen, Matthias Trost and Miratul MK Muqit

    Version of Record online : 16 OCT 2015, DOI: 10.15252/embj.201591593

  7. Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson's disease

    Journal of Neuroscience Research

    Volume 93, Issue 11, November 2015, Pages: 1713–1727, Laura M. Grant, Cynthia A. Kelm-Nelson, Breanna L. Hilby, Katherine V. Blue, Eunice S. Paul Rajamanickam, Joshua D. Pultorak, Shelia M. Fleming and Michelle R. Ciucci

    Version of Record online : 31 JUL 2015, DOI: 10.1002/jnr.23625

  8. You have full text access to this OnlineOpen article
    Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

    EMBO Molecular Medicine

    Volume 1, Issue 2, May 2009, Pages: 99–111, Vanessa A. Morais, Patrik Verstreken, Anne Roethig, Joél Smet, An Snellinx, Mieke Vanbrabant, Dominik Haddad, Christian Frezza, Wim Mandemakers, Daniela Vogt-Weisenhorn, Rudy Van Coster, Wolfgang Wurst, Luca Scorrano and Bart De Strooper

    Version of Record online : 21 APR 2009, DOI: 10.1002/emmm.200900006

  9. PINK1 heterozygous mutations induce subtle alterations in dopamine-dependent synaptic plasticity

    Movement Disorders

    Volume 29, Issue 1, January 2014, Pages: 41–53, Graziella Madeo, Tommaso Schirinzi, Giuseppina Martella, E. Claudio Latagliata, Francesca Puglisi, Jie Shen, Enza Maria Valente, Mauro Federici, Nicola B. Mercuri, Stefano Puglisi-Allegra, Paola Bonsi and Antonio Pisani

    Version of Record online : 25 OCT 2013, DOI: 10.1002/mds.25724

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    Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

    The EMBO Journal

    Volume 31, Issue 14, July 18, 2012, Pages: 3038–3062, Nicole Exner, Anne Kathrin Lutz, Christian Haass and Konstanze F Winklhofer

    Version of Record online : 26 JUN 2012, DOI: 10.1038/emboj.2012.170

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    Phylogenetic and in silico structural analysis of the Parkinson disease-related kinase PINK1

    Human Mutation

    Volume 32, Issue 4, April 2011, Pages: 369–378, Fernando Cardona, Jose Vicente Sánchez-Mut, Hernán Dopazo and Jordi Pérez-Tur

    Version of Record online : 15 MAR 2011, DOI: 10.1002/humu.21444

  12. Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1

    European Journal of Neuroscience

    Volume 41, Issue 9, May 2015, Pages: 1113–1125, Celia van der Merwe, Zahra Jalali Sefid Dashti, Alan Christoffels, Ben Loos and Soraya Bardien

    Version of Record online : 11 MAR 2015, DOI: 10.1111/ejn.12872

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    Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

    Journal of Neurochemistry

    Volume 98, Issue 1, July 2006, Pages: 156–169, Miratul M. K. Muqit, Patrick M. Abou-Sleiman, Adrian T. Saurin, Kirsten Harvey, Sonia Gandhi, Emma Deas, Simon Eaton, Martin D. Payne Smith, Kerrie Venner, Antoni Matilla, Daniel G. Healy, William P. Gilks, Andrew J. Lees, Janice Holton, Tamas Revesz, Peter J. Parker, Robert J. Harvey, Nicholas W. Wood and David S. Latchman

    Version of Record online : 18 MAY 2006, DOI: 10.1111/j.1471-4159.2006.03845.x

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    The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

    Journal of Neurochemistry

    Volume 117, Issue 5, June 2011, Pages: 856–867, Cathrin Meissner, Holger Lorenz, Andreas Weihofen, Dennis J. Selkoe and Marius K. Lemberg

    Version of Record online : 13 APR 2011, DOI: 10.1111/j.1471-4159.2011.07253.x

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    The Parkinson's disease-associated gene PINK1 protects neurons from ischemic damage by decreasing mitochondrial translocation of the fission promoter Drp1

    Journal of Neurochemistry

    Volume 127, Issue 5, December 2013, Pages: 711–722, Yanxin Zhao, Fangzhe Chen, Shufen Chen, Xueyuan Liu, Mei Cui and Qiang Dong

    Version of Record online : 30 JUN 2013, DOI: 10.1111/jnc.12340

  16. You have free access to this content
    Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A

    Journal of Neurochemistry

    Volume 128, Issue 6, March 2014, Pages: 864–877, Ruben K. Dagda, Irene Pien, Ruth Wang, Jianhui Zhu, Kent Z. Q. Wang, Jason Callio, Tania Das Banerjee, Raul Y. Dagda and Charleen T. Chu

    Version of Record online : 13 NOV 2013, DOI: 10.1111/jnc.12494

  17. Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice

    Synapse

    Volume 70, Issue 6, June 2016, Pages: 223–230, Marco Feligioni, Dalila Mango, Sonia Piccinin, Paola Imbriani, Filomena Iannuzzi, Alessandra Caruso, Francesca De Angelis, Fabio Blandini, Nicola B. Mercuri, Antonio Pisani and Robert Nisticò

    Version of Record online : 29 FEB 2016, DOI: 10.1002/syn.21894

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    Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy

    EMBO reports

    Volume 15, Issue 1, January 2014, Pages: 86–93, Maja A. Fedorowicz, Rosa L. A. de Vries-Schneider, Cornelia Rüb, Dorothea Becker, Yong Huang, Chun Zhou, Dana M. Alessi Wolken, Wolfgang Voos, Yuhui Liu and Serge Przedborski

    Version of Record online : 18 DEC 2013, DOI: 10.1002/embr.201337294

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    PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

    FEBS Letters

    Volume 584, Issue 6, March 19, 2010, Pages: 1073–1079, Sumihiro Kawajiri, Shinji Saiki, Shigeto Sato, Fumiaki Sato, Taku Hatano, Hiroto Eguchi and Nobutaka Hattori

    Version of Record online : 12 FEB 2010, DOI: 10.1016/j.febslet.2010.02.016

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    Characterization of PINK1 processing, stability, and subcellular localization

    Journal of Neurochemistry

    Volume 106, Issue 1, July 2008, Pages: 464–474, William Lin and Un Jung Kang

    Version of Record online : 5 APR 2008, DOI: 10.1111/j.1471-4159.2008.05398.x