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There are 1138 results for: content related to: Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease

  1. UNC51-like kinase 1, autophagic regulator and cancer therapeutic target

    Cell Proliferation

    Volume 47, Issue 6, December 2014, Pages: 494–505, Y. Chen, J. He, M. Tian, S.-Y. Zhang, M.-R. Guo, R. Kasimu, J.-H. Wang and L. Ouyang

    Article first published online : 20 OCT 2014, DOI: 10.1111/cpr.12145

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    Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma

    Cancer Science

    Volume 102, Issue 8, August 2011, Pages: 1568–1575, Shan Jiang, Yong Li, Ying-Hui Zhu, Xiao-Qi Wu, Jun Tang, Zheng Li, Gong-Kan Feng, Rong Deng, Dan-Dan Li, Rong-Zhen Luo, Mei-Fang Zhang, Wei Qin, Xin Wang, Wei-Hua Jia and Xiao-Feng Zhu

    Article first published online : 31 MAY 2011, DOI: 10.1111/j.1349-7006.2011.01964.x

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    Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1

    FEBS Journal

    Volume 281, Issue 17, September 2014, Pages: 3816–3827, Seung-Hyun Ro, Ian A. Semple, Haewon Park, Haeli Park, Hwan-Woo Park, Myungjin Kim, Jeong Sig Kim and Jun Hee Lee

    Article first published online : 28 JUL 2014, DOI: 10.1111/febs.12905

  4. AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

    Journal of Cellular Biochemistry

    Volume 113, Issue 2, February 2012, Pages: 695–710, Anthony MJ Sanchez, Alfredo Csibi, Audrey Raibon, Karen Cornille, Stéphanie Gay, Henri Bernardi and Robin Candau

    Article first published online : 5 JAN 2012, DOI: 10.1002/jcb.23399

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    ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

    EMBO reports

    Volume 15, Issue 5, May 2014, Pages: 566–575, Wenxian Wu, Weili Tian, Zhe Hu, Guo Chen, Lei Huang, Wen Li, Xingli Zhang, Peng Xue, Changqian Zhou, Lei Liu, Yushan Zhu, Xingliang Zhang, Longxuan Li, Liangqing Zhang, Senfang Sui, Bin Zhao and Du Feng

    Article first published online : 26 MAR 2014, DOI: 10.1002/embr.201438501

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    Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC

    The EMBO Journal

    Volume 31, Issue 8, April 18, 2012, Pages: 1931–1946, Nicole C McKnight, Harold B J Jefferies, Endalkachew A Alemu, Rebecca E Saunders, Michael Howell, Terje Johansen and Sharon A Tooze

    Article first published online : 21 FEB 2012, DOI: 10.1038/emboj.2012.36

  7. Alteration of Upstream Autophagy-Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease

    Brain Pathology

    Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi and Koichi Wakabayashi

    Article first published online : 8 SEP 2015, DOI: 10.1111/bpa.12297

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    Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

    The EMBO Journal

    Volume 31, Issue 18, September 12, 2012, Pages: 3691–3703, Claudine Kraft, Monika Kijanska, Eyal Kalie, Edyta Siergiejuk, Sung Sik Lee, Giuseppe Semplicio, Ingrid Stoffel, Andrea Brezovich, Mayanka Verma, Isabella Hansmann, Gustav Ammerer, Kay Hofmann, Sharon Tooze and Matthias Peter

    Article first published online : 10 AUG 2012, DOI: 10.1038/emboj.2012.225

  9. Early and Sustained Activation of Autophagy in Degenerating Axons after Spinal Cord Injury

    Brain Pathology

    Volume 25, Issue 2, March 2015, Pages: 157–170, Vinicius Toledo Ribas, Bianca Schnepf, Malleswari Challagundla, Jan Christoph Koch, Mathias Bähr and Paul Lingor

    Article first published online : 12 SEP 2014, DOI: 10.1111/bpa.12170

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    Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of mTORC1 complex components in human cancer cells

    FEBS Journal

    Volume 281, Issue 20, October 2014, Pages: 4644–4658, Pramod Aryal, Kijoong Kim, Pil-Hoon Park, Seongho Ham, Junghee Cho and Kyung Song

    Article first published online : 11 SEP 2014, DOI: 10.1111/febs.12969

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    Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

    Arthritis & Rheumatism

    Volume 62, Issue 3, March 2010, Pages: 791–801, Beatriz Caramés, Noboru Taniguchi, Shuhei Otsuki, Francisco J. Blanco and Martin Lotz

    Article first published online : 25 FEB 2010, DOI: 10.1002/art.27305

  12. Transcription factors and cognate signalling cascades in the regulation of autophagy

    Biological Reviews

    Vemika Chandra, Ella Bhagyaraj, Raman Parkesh and Pawan Gupta

    Article first published online : 4 FEB 2015, DOI: 10.1111/brv.12177

  13. KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation

    The EMBO Journal

    Volume 34, Issue 19, 1 October 2015, Pages: 2441–2464, Craig R Brooks, Melissa Y Yeung, Yang S Brooks, Hui Chen, Takaharu Ichimura, Joel M Henderson and Joseph V Bonventre

    Article first published online : 17 AUG 2015, DOI: 10.15252/embj.201489838

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    Post-translationally-modified structures in the autophagy machinery: an integrative perspective

    FEBS Journal

    Volume 282, Issue 18, September 2015, Pages: 3474–3488, Hana Popelka and Daniel J. Klionsky

    Article first published online : 16 JUL 2015, DOI: 10.1111/febs.13356

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    Autophagy plays a protective role as an anti-oxidant system in human T cells and represents a novel strategy for induction of T-cell apoptosis

    European Journal of Immunology

    Volume 44, Issue 8, August 2014, Pages: 2508–2520, Ryu Watanabe, Hiroshi Fujii, Tsuyoshi Shirai, Shinichiro Saito, Tomonori Ishii and Hideo Harigae

    Article first published online : 16 JUN 2014, DOI: 10.1002/eji.201344248

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    Atg1-mediated myosin II activation regulates autophagosome formation during starvation-induced autophagy

    The EMBO Journal

    Volume 30, Issue 4, February 16, 2011, Pages: 636–651, Hong-Wen Tang, Yu-Bao Wang, Shiu-Lan Wang, Mei-Hsuan Wu, Shu-Yu Lin and Guang-Chao Chen

    Article first published online : 17 DEC 2010, DOI: 10.1038/emboj.2010.338

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    Translational repression stabilizes messenger RNA of autophagy-related genes

    Genes to Cells

    Volume 16, Issue 8, August 2011, Pages: 857–867, Bilon Khambu, Motonari Uesugi and Yoshinori Kawazoe

    Article first published online : 25 JUL 2011, DOI: 10.1111/j.1365-2443.2011.01532.x

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    FIP200 regulates targeting of Atg16L1 to the isolation membrane

    EMBO reports

    Volume 14, Issue 3, March 2013, Pages: 284–291, Taki Nishimura, Takeshi Kaizuka, Ken Cadwell, Mayurbhai H Sahani, Tatsuya Saitoh, Shizuo Akira, Herbert W Virgin and Noboru Mizushima

    Article first published online : 8 FEB 2013, DOI: 10.1038/embor.2013.6

  19. Unravelling the multifaceted roles of Atg proteins to improve cancer therapy

    Cell Proliferation

    Volume 47, Issue 2, April 2014, Pages: 105–112, Y. Chen, X.-R. Liu, Y.-Q. Yin, C.-J. Lee, F.-T. Wang, H.-Q. Liu, X.-T. Wu and J. Liu

    Article first published online : 23 FEB 2014, DOI: 10.1111/cpr.12095

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    Trafficking and signaling in mammalian autophagy

    IUBMB Life

    Volume 62, Issue 7, July 2010, Pages: 503–508, Sharon A. Tooze, Harold B. J. Jefferies, Eyal Kalie, Andrea Longatti, Fiona E. Mcalpine, Nicole C. Mcknight, Andrea Orsi, Hannah E. J. Polson, Minoo Razi, Deborah J. Robinson and Jemma L. Webber

    Article first published online : 26 APR 2010, DOI: 10.1002/iub.334