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There are 19181 results for: content related to: Novel thiopurine methyltransferase variant TPMT*28 results in a misdiagnosis of TPMT deficiency

  1. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 5 MAY 2015, DOI: 10.1111/bjh.13469

  2. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 29 NOV 2014, DOI: 10.1111/bjh.13240

  3. You have free access to this content
    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Version of Record online : 20 MAR 2014, DOI: 10.1111/bcp.12226

  4. Influence of the variable number of tandem repeats located in the promoter region of the thiopurine methyltransferase gene on enzymatic activity

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 2, August 2001, Pages: 165–174, Sandra Alves, António Amorim, Fátima Ferreira and Maria João Prata

    Version of Record online : 11 AUG 2001, DOI: 10.1067/mcp.2001.117284

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    Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

    British Journal of Clinical Pharmacology

    Volume 48, Issue 6, December 1999, Pages: 793–800, Dervieux, Médard, Baudouin, Maisin, Zhang, Broly, Loirat and Jacqz-Aigrain

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00087.x

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    Tracing the Origin of the Most Common Thiopurine Methyltransferase (TPMT) Variants: Preliminary Data from the Patterns of Haplotypic Association with Two CA Repeats

    Annals of Human Genetics

    Volume 68, Issue 4, July 2004, Pages: 313–323, S. Alves, J. Rocha, A. Amorim and M. J. Prata

    Version of Record online : 28 JUN 2004, DOI: 10.1046/j.1529-8817.2004.00104.x

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    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Version of Record online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  8. Thiopurine methyltransferase polymorphic tandem repeat: Genotype-phenotype correlation analysis

    Clinical Pharmacology & Therapeutics

    Volume 68, Issue 2, August 2000, Pages: 210–219, Lan Yan, Shuichen Zhang, Bianca Eiff, Carol L. Szumlanski, Melody Powers, John F. O'Brien and Richard M. Weinshilboum

    Version of Record online : 5 AUG 2000, DOI: 10.1067/mcp.2000.108674

  9. Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms

    Clinical Pharmacology & Therapeutics

    Volume 62, Issue 1, July 1997, Pages: 60–73, Diane Otterness, Carol Szumlanski, Lynne Lennard, Bjørg Klemetsdal, Jarle Aarbakke, Jeong Ok Park-Hah, Heiko Iven, Kjeld Schmiegelow, Earl Branum, John O'Brien and Richard Weinshilboum

    Version of Record online : 14 JUL 1997, DOI: 10.1016/S0009-9236(97)90152-1

  10. Detection of one single mutation predicts thiopurine S-methyltransferase activity in a population of Saami in northern Norway

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 2, August 2001, Pages: 183–188, Thrina Loennechen, Egil Utsi, Ingeborg Hartz, Roy Lysaa, Hanne Kildalsen and Jarle Aarbakke

    Version of Record online : 11 AUG 2001, DOI: 10.1067/mcp.2001.117445

  11. Normal thiopurine methyltransferase phenotype testing in a Crohn disease patient with azathioprine induced myelosuppression

    Internal Medicine Journal

    Volume 39, Issue 2, February 2009, Pages: 121–126, M. Leung, 1 I. Piatkov, 2 C. Rochester, 2 S. C. Boyages and 2 R. W. L. Leong 1

    Version of Record online : 31 MAR 2009, DOI: 10.1111/j.1445-5994.2008.01855.x

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    Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 16, Issue 10, October 2002, Pages: 1743–1750, A. Ansari, C. Hassan, J. Duley, A. Marinaki, E. -M. Shobowale-Bakre, P. Seed, J. Meenan, A. Yim and J. Sanderson

    Version of Record online : 19 SEP 2002, DOI: 10.1046/j.1365-2036.2002.01353.x

  13. Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: a meta-analysis of three genome-wide association studies

    Clinical Pharmacology & Therapeutics

    Accepted manuscript online: 22 OCT 2016, Riin Tamm, Reedik Mägi, Roman Tremmel, Stefan Winter, Evelin Mihailov, Alenka Smid, Anja Möricke, Kathrin Klein, Martin Schrappe, Martin Stanulla, Richard Houlston, Richard Weinshilboum, Irena Mlinarič Raščan, Andres Metspalu, Lili Milani, Matthias Schwab and Elke Schaeffeler

    DOI: 10.1002/cpt.540

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    Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 25, Issue 9, May 2007, Pages: 1069–1077, J. W. WINTER, D. GAFFNEY, D SHAPIRO, R. J. SPOONER, A. M. MARINAKI, J. D. SANDERSON and P. R. MILLS

    Version of Record online : 22 FEB 2007, DOI: 10.1111/j.1365-2036.2007.03301.x

  15. Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait

    Clinical Pharmacology & Therapeutics

    C Liu, W Yang, D Pei, C Cheng, C Smith, W Landier, L Hageman, Y Chen, JJ Yang, KR Crews, N Kornegay, SE Karol, FL Wong, S Jeha, JT Sandlund, RC Ribeiro, JE Rubnitz, ML Metzger, C-H Pui, WE Evans, S Bhatia and MV Relling

    Version of Record online : 18 NOV 2016, DOI: 10.1002/cpt.463

  16. Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans

    Clinical Pharmacology & Therapeutics

    Volume 64, Issue 1, July 1998, Pages: 46–51, Thrina Loennechen, Charles R. Yates, Michael Y. Fessing, Mary V. Relling, Eugene Y. Krynetski and William E. Evans

    Version of Record online : 11 JUL 1998, DOI: 10.1016/S0009-9236(98)90021-2

  17. Using HapMap Tools in Pharmacogenomic Discovery: The Thiopurine Methyltransferase Polymorphism

    Clinical Pharmacology & Therapeutics

    Volume 81, Issue 5, May 2007, Pages: 729–734, T S Jones, W Yang, W E Evans and M V Relling

    Version of Record online : 28 FEB 2007, DOI: 10.1038/sj.clpt.6100135

  18. Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis

    Human Mutation

    Volume 12, Issue 3, 1998, Pages: 177–185, Catherine Spire-Vayron de la Moureyre, Hervé Debuysère, Nadda Sabbagh, Delphine Marez, Elizabeth Vinner, Emmanuel Dany Chevalier, Jean-Marc Lo Guidice and Franck Broly

    Version of Record online : 7 JAN 1999, DOI: 10.1002/(SICI)1098-1004(1998)12:3<177::AID-HUMU5>3.0.CO;2-E

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    A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations

    British Journal of Haematology

    Volume 110, Issue 3, September 2000, Pages: 599–604, Sally A. Coulthard, Celia Rabello, Jill Robson, Christopher Howell, Lynne Minto, Peter G. Middleton, Maher K. Gandhi, Graham Jackson, Janet McLelland, Hugh O'brien, Stephen Smith, Michael M. Reid, Andrew D. J. Pearson and Andrew G. Hall

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2141.2000.02218.x

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    British Association of Dermatologists’ guidelines for the safe and effective prescribing of azathioprine 2011

    British Journal of Dermatology

    Volume 165, Issue 4, October 2011, Pages: 711–734, S.J. Meggitt, A.V. Anstey, M.F. Mohd Mustapa, N.J. Reynolds and S. Wakelin

    Version of Record online : 27 SEP 2011, DOI: 10.1111/j.1365-2133.2011.10575.x